阅读说明：本技术 用于制备3α-羟基-5α-孕烷-20-酮(布瑞诺龙)的工艺 (Process for the preparation of 3 alpha-hydroxy-5 alpha-pregnan-20-one (breynolone) ) 是由 克劳迪奥·德尔弗拉特 达维德·里加蒙蒂 迪·博雷利 罗伯托·莱纳 于 2019-10-21 设计创作，主要内容包括：本发明涉及用于合成3α-羟基-5α-孕烷-20-酮的新工艺,3α-羟基-5α-孕烷-20-酮通常被称为布瑞诺龙,其中式(IV)的相应的环状20-缩酮化合物或环状20-酮缩硫醇化合物在有机溶剂中使用碘进行脱保护。(The present invention relates to a novel process for the synthesis of 3 α -hydroxy-5 α -pregnan-20-one, commonly known as breynolone, wherein the corresponding cyclic 20-ketal compound or cyclic 20-ketothioketal compound of formula (IV) is deprotected with iodine in an organic solvent.)