阅读说明：本技术 针对骨硬化蛋白的适体的诊断用途 (Diagnostic use of aptamers against sclerostin ) 是由 何伊欣 于媛媛 倪帅健 张戈 于 2019-02-11 设计创作，主要内容包括：一种适体及其在诊断骨硬化蛋白相关疾病中的应用,所述适体包含与SEQ ID NO:1-17中的任一具有至少大约90％相同性、至少大约91％相同性、至少大约92％相同性、至少大约93％相同性、至少大约94％相同性、至少大约95％相同性的核苷酸序列,或者,所述适体包含SEQ ID NO:1-17中的任一中的至少30个、至少35个、至少40个、至少45个、至少50个或更多个连续的核苷酸,所述适体特异性结合骨硬化蛋白。(An aptamer comprising a nucleotide sequence that is at least about 90% identical, at least about 91% identical, at least about 92% identical, at least about 93% identical, at least about 94% identical, at least about 95% identical to any one of SEQ ID NOs 1-17 or at least 30, at least 35, at least 40, at least 45, at least 50, or more contiguous nucleotides of any one of SEQ ID NOs 1-17 and its use in diagnosing a sclerostin-related disease, the aptamer specifically binding to sclerostin.)