阅读说明：本技术 基于多生理信号融合实时监测的针灸刺激评估方法及系统 (Acupuncture stimulation evaluation method and system based on multi-physiological signal fusion real-time monitoring ) 是由 任韦燕 刘红梅 李增勇 栾会芹 樊瑜波 于 2021-07-06 设计创作，主要内容包括：本发明公开了一种基于多生理信号融合实时监测的针灸刺激评估方法及系统,方法：通过脑血氧含量、皮肤血氧饱和度、皮肤血流量、皮肤电活动值和皮肤温度对针灸效果进行评估；系统：包括治疗床,治疗床的一侧设有计算机,计算机通过脑血氧信号处理器连接近红外光谱探头,计算机通过皮肤血氧信号处理器连接第一皮肤血氧探头和第二皮肤血氧探头,计算机通过皮肤血流信号处理器连接第一皮肤血流探头和第二皮肤血流探头,计算机通过电生理信号处理器连接皮肤电导传感器和皮肤温度传感器,皮肤电导传感器有两个。本发明具有可对针灸之于人体多种生理参数的影响进行评估的优点,有助于医生理解明针灸治疗幻肢痛的作用机理,并提供依据。(The invention discloses an acupuncture stimulation evaluation method and system based on multi-physiological signal fusion real-time monitoring, wherein the method comprises the following steps: evaluating acupuncture effect through cerebral blood oxygen content, skin blood oxygen saturation, skin blood flow, skin electrical activity value and skin temperature; the system comprises the following steps: including the treatment bed, one side of treatment bed is equipped with the computer, the computer passes through brain blood oxygen signal processor and connects near infrared spectrum probe, the computer passes through skin blood oxygen signal processor and connects first skin blood oxygen probe and second skin blood oxygen probe, the computer passes through skin blood flow signal processor and connects first skin blood flow probe and second skin blood flow probe, the computer passes through electrophysiological signal processor and connects skin conductance sensor and skin temperature sensor, skin conductance sensor has two. The invention has the advantage of evaluating the influence of acupuncture on various physiological parameters of human bodies, is helpful for doctors to understand the action mechanism of acupuncture for treating phantom limb pain and provides basis.)

1. An acupuncture stimulation evaluation method based on multi-physiological signal fusion real-time monitoring is characterized in that: the acupuncture effect is evaluated by the cerebral blood oxygen content, the skin blood oxygen saturation, the skin blood flow, the skin electrical activity value and the skin temperature.

2. The system for assessing acupuncture stimulation based on multi-physiological signal fusion real-time monitoring according to claim 1, wherein: including treatment bed (1), one side of treatment bed (1) is equipped with computer (13), near infrared spectrum probe (3) are connected through brain blood oxygen signal processor (2) in computer (13), first skin blood oxygen probe (5) and second skin blood oxygen probe (6) are connected through skin blood oxygen signal processor (4) in computer (13), first skin blood flow probe (8) and second skin blood flow probe (9) are connected through skin blood flow signal processor (7) in computer (13), skin conductivity sensor (11) and skin temperature sensor (12) are connected through electrophysiology signal processor (10) in computer (13), skin conductivity sensor (11) have two.

3. The system for assessing acupuncture stimulation based on multi-physiological signal fusion real-time monitoring according to claim 2, wherein: the near infrared spectrum probe (3) comprises twelve brain blood oxygen signal channels (32).

4. The system for assessing acupuncture stimulation based on multi-physiological signal fusion real-time monitoring according to claim 2, wherein: and the near infrared spectrum probe (3) is attached to the forehead region of the head of the patient to obtain a brain blood oxygen content fluctuation signal of the head of the patient, and the brain blood oxygen signal processor (2) processes the brain blood oxygen content fluctuation signal to form a brain blood oxygen content fluctuation curve which is displayed on a display of a computer (13).

5. The system for assessing acupuncture stimulation based on multi-physiological signal fusion real-time monitoring according to claim 2, wherein: attaching a first skin blood oxygen probe (5) to an acupuncture position, attaching a second skin blood oxygen probe (6) to the limb part opposite to the acupuncture position, or attaching the first skin blood oxygen probe (5) to the acupuncture position, and attaching the second skin blood oxygen probe (6) to the far end part of the acupuncture position to obtain two skin blood oxygen saturation fluctuation signals; the skin blood oxygen signal processor (4) processes the two skin blood oxygen saturation fluctuation signals to form two skin blood oxygen saturation fluctuation curves which are displayed on a display of the computer (13).

6. The system for assessing acupuncture stimulation based on multi-physiological signal fusion real-time monitoring according to claim 2, wherein: a first skin blood flow probe (8) is attached to an acupuncture part, a second skin blood flow probe (9) is attached to the limb part opposite to the acupuncture part, or the first skin blood flow probe (8) is attached to the acupuncture part, the second skin blood flow probe (9) is attached to the far end part of the acupuncture part, two skin blood flow fluctuation signals are obtained, and a skin blood flow signal processor (7) processes the two skin blood flow fluctuation signals to form two skin blood flow curves which are displayed on a display of a computer (13).

7. The system for assessing acupuncture stimulation based on multi-physiological signal fusion real-time monitoring according to claim 2, wherein: one skin conductance sensor (11) is connected with the index finger abdomen of the patient, the other skin conductance sensor (11) is connected with the middle finger abdomen of the patient to obtain skin electrical activity signals, and the electrophysiological signal processor (10) processes the skin electrical activity signals to form a skin electrical activity value curve which is displayed on a display of a computer (13).

8. The system for assessing acupuncture stimulation based on multi-physiological signal fusion real-time monitoring according to claim 2, wherein: the skin temperature sensor (12) is connected with the abdomen of the ring finger of the patient to obtain a skin temperature signal, and the electrophysiological signal processor (10) processes the skin temperature signal to form a skin temperature curve which is displayed on the display of the computer (13).

9. The system for assessing acupuncture stimulation based on multi-physiological signal fusion real-time monitoring according to claim 2, wherein: the treatment bed (1) comprises a bed plate, a first support (21) is arranged below one end of the bed plate, a first driving mechanism for driving one end of the bed plate to lift is arranged on the first support (21), a second support (23) is arranged below the other end of the bed plate, and the second support (23) is hinged to the other end of the bed plate.

10. The system for assessing acupuncture stimulation based on multi-physiological signal fusion real-time monitoring according to claim 9, wherein: the bed board comprises three rotating plates (20) which are connected in series, a gap is formed between every two adjacent rotating plates (20), an elastic band (22) for filling the gap is arranged between every two adjacent rotating plates (20), and a second driving mechanism is arranged between every two adjacent rotating plates (20).

Technical Field

The invention relates to an acupuncture stimulation evaluation method and system based on multi-physiological signal fusion real-time monitoring.

Background

Phantom limb pain is one of the most common postoperative complications for amputees. Amputated limbs of patients are often accompanied by pain of varying degrees and characteristics, which seriously affects the quality of life of amputees. Acupuncture is a conservative treatment, and its efficacy is given certainty. However, the action mechanism of acupuncture for treating phantom limb pain is not clearly explained, and how acupuncture stimulation is to relieve the sensation of phantom limb pain is also lack of basis, so that doctors have difficulty in further improving the acupuncture mode in a targeted manner, thereby improving the treatment effect of acupuncture. Therefore, there is a need for an evaluation method to evaluate the effects of acupuncture stimulation on various physiological parameters of the human body, so as to help doctors understand the action mechanism of acupuncture therapy for phantom limb pain and provide the basis.

Disclosure of Invention

The invention aims to provide an acupuncture stimulation evaluation method and system based on multi-physiological signal fusion real-time monitoring. The invention has the advantage of evaluating the influence of acupuncture on various physiological parameters of human bodies, is helpful for doctors to understand the action mechanism of acupuncture for treating phantom limb pain and provides basis.

The technical scheme of the invention is as follows: an acupuncture stimulation evaluation method based on multi-physiological signal fusion real-time monitoring is used for evaluating acupuncture effects through cerebral blood oxygen content, skin blood oxygen saturation, skin blood flow, skin electrical activity values and skin temperature.

Aforementioned acupuncture stimulation evaluation system based on many physiological signal fuse real-time supervision, including the treatment bed, one side of treatment bed is equipped with the computer, the computer passes through brain blood oxygen signal processor and connects near infrared spectrum probe, the computer passes through skin blood oxygen signal processor and connects first skin blood oxygen probe and second skin blood oxygen probe, the computer passes through skin blood flow signal processor and connects first skin blood flow probe and second skin blood flow probe, the computer passes through electrophysiological signal processor and connects skin conductance sensor and skin temperature sensor, skin conductance sensor has two.

In the aforementioned acupuncture stimulation evaluation system based on multi-physiological signal fusion real-time monitoring, the near infrared spectrum probe includes twelve brain blood oxygen signal channels in total.

In the acupuncture stimulation evaluation system based on multi-physiological signal fusion real-time monitoring, the near infrared spectrum probe is attached to the forehead region of the head of the patient to obtain a brain blood oxygen content fluctuation signal of the head of the patient, and the brain blood oxygen signal processor processes the brain blood oxygen content fluctuation signal to form a brain blood oxygen content fluctuation curve which is displayed on a display of a computer.

In the aforementioned acupuncture stimulation evaluation system based on multi-physiological signal fusion real-time monitoring, the first skin blood oxygen probe is attached to the acupuncture site, the second skin blood oxygen probe is attached to the opposite limb of the acupuncture site, or the first skin blood oxygen probe is attached to the acupuncture site, and the second skin blood oxygen probe is attached to the distal end of the acupuncture site, so as to obtain two fluctuation signals of the skin blood oxygen saturation; the skin blood oxygen signal processor processes the two skin blood oxygen saturation fluctuation signals to form two skin blood oxygen saturation fluctuation curves which are displayed on a display of a computer.

In the acupuncture stimulation evaluation system based on multi-physiological signal fusion real-time monitoring, the first skin blood flow probe is attached to the acupuncture position, the second skin blood flow probe is attached to the opposite limb position of the acupuncture position, or the first skin blood flow probe is attached to the acupuncture position, and the second skin blood flow probe is attached to the far end position of the acupuncture position, so that two skin blood flow fluctuation signals are obtained, and the two skin blood flow fluctuation signals are processed by the skin blood flow signal processor to form two skin blood flow curves which are displayed on a display of a computer.

In the acupuncture stimulation evaluation system based on multi-physiological signal fusion real-time monitoring, one of the skin conductance sensors is connected with the index finger abdomen of the patient, the other skin conductance sensor is connected with the middle finger abdomen of the patient to obtain skin electrical activity signals, and the skin electrical activity signals are processed by the electrophysiological signal processor to form a skin electrical activity value curve which is displayed on a display of a computer.

In the acupuncture stimulation evaluation system based on multi-physiological signal fusion real-time monitoring, the skin temperature sensor is connected with the finger abdomen of the ring finger of the patient to obtain a skin temperature signal, and the electrophysiological signal processor processes the skin temperature signal to form a skin temperature curve which is displayed on a display of a computer.

In the acupuncture stimulation evaluation system based on multi-physiological signal fusion real-time monitoring, the treatment bed comprises a bed plate, a first support is arranged below one end of the bed plate, a first driving mechanism for driving one end of the bed plate to ascend and descend is arranged on the first support, a second support is arranged below the other end of the bed plate, and the second support is hinged to the other end of the bed plate.

In the acupuncture stimulation evaluation system based on multi-physiological signal fusion real-time monitoring, the bed plate and the bed plate are composed of three rotating plates connected in series, a gap is formed between every two adjacent rotating plates, an elastic band for filling the gap is arranged between every two adjacent rotating plates, and a second driving mechanism is arranged between every two adjacent rotating plates.

Compared with the prior art, the invention judges the effect of acupuncture on the brain area through the change of the brain blood oxygen content, judges the effect of acupuncture on the microcirculation oxygen supply level through the change of the skin blood oxygen saturation and the skin blood flow volume, judges the effect of acupuncture on the sweat gland function through the change of the skin electrical activity value, and judges the effect of acupuncture on the blood circulation of the periphery of a human body through the change of the skin temperature, thereby being beneficial to doctors to understand the action mechanism of acupuncture for treating phantom limb pain and providing a basis.

Drawings

Fig. 1 is a schematic structural view of the present invention.

Fig. 2 is a front view of the treatment couch.

The labels in the figures are: 1-treatment bed, 2-cerebral blood oxygen signal processor, 3-near infrared spectrum probe, 4-skin blood oxygen signal processor, 5-first skin blood oxygen probe, 6-second skin blood oxygen probe, 7-skin blood flow signal processor, 8-first skin blood flow probe, 9-second skin blood flow probe, 10-electrophysiological signal processor, 11-skin conductance sensor, 12-skin temperature sensor, 13-computer, 20-rotating plate, 21-first bracket, 22-elastic band, 23-second bracket, 24-first electric cylinder, 25-first rotating plate, 26-second rotating plate, 27-second electric cylinder, 28-sphere and 29-hinge.

Detailed Description

The invention is further illustrated by the following figures and examples, which are not to be construed as limiting the invention.

Examples are given. An acupuncture stimulation evaluation method based on multi-physiological signal fusion real-time monitoring is used for evaluating acupuncture effects through cerebral blood oxygen content, skin blood oxygen saturation, skin blood flow, skin electrical activity values and skin temperature.

Acupuncture stimulation evaluation system based on many physiological signal fuse real-time supervision includes treatment bed 1, one side of treatment bed 1 is equipped with computer 13, computer 13 passes through brain blood oxygen signal processor 2 and connects near infrared spectrum probe 3, computer 13 passes through skin blood oxygen signal processor 4 and connects first skin blood oxygen probe 5 and second skin blood oxygen probe 6, computer 13 passes through skin blood flow signal processor 7 and connects first skin blood flow probe 8 and second skin blood flow probe 9, computer 13 passes through electrophysiological signal processor 10 and connects skin conductance sensor 11 and skin temperature sensor 12, skin conductance sensor 11 has two.

The near infrared spectrum probe 3 comprises four light source optical fibers 30 and six detector optical fibers 31, which form twelve brain blood oxygen signal channels 32.

And the near infrared spectrum probe 3 is attached to the forehead region of the head of the patient to obtain a brain blood oxygen content fluctuation signal of the head of the patient, and the brain blood oxygen signal processor 2 processes the brain blood oxygen content fluctuation signal to form a brain blood oxygen content fluctuation curve which is displayed on a display of the computer 13. The prefrontal lobe is a measurement area which reflects the best brain blood oxygen content, and when acupuncture is carried out, the brain blood oxygen content changes, namely the oxygen-containing hemoglobin value of the brain is increased or decreased, so that the change of the brain area metabolic level is proved, and the good and bad activation conditions of the brain area are reflected.

Attaching the first skin blood oxygen probe 5 to the acupuncture position and the second skin blood oxygen probe 6 to the opposite limb position of the acupuncture position through double faced adhesive tapes, or attaching the first skin blood oxygen probe 5 to the acupuncture position and the second skin blood oxygen probe 6 to the far end position of the acupuncture position to obtain two skin blood oxygen saturation fluctuation signals; the skin blood oxygen signal processor 4 processes the two skin blood oxygen saturation fluctuation signals to form two skin blood oxygen saturation fluctuation curves, and the two skin blood oxygen saturation fluctuation curves are displayed on a display of the computer 13. The oxygen saturation of the skin can reflect the oxygen supply level of microcirculation to the skin soft tissues, and if the oxygen saturation of the skin of a patient rises in the acupuncture process, the oxygen supply level of the microcirculation is increased, so that the effect of acupuncture on improving the microcirculation of the measurement area is reflected.

A first skin blood flow probe 8 is attached to an acupuncture part and a second skin blood flow probe 9 is attached to a limb part opposite to the acupuncture part through double faced adhesive tapes, or the first skin blood flow probe 8 is attached to the acupuncture part and the second skin blood flow probe 9 is attached to a far end part of the acupuncture part to obtain two skin blood flow fluctuation signals, and the two skin blood flow fluctuation signals are processed by a skin blood flow signal processor 7 to form two skin blood flow curves which are displayed on a display of a computer 13. The skin blood flow can reflect the blood flow supply level of microcirculation to skin soft tissues, and during the acupuncture process, if the skin blood flow of a patient is increased, the blood supply level of the microcirculation is increased, and the effect of acupuncture on improving the microcirculation of the measurement area is reflected.

One skin conductance sensor 11 is connected with the index finger abdomen of a patient through a finger stall, the other skin conductance sensor 11 is connected with the middle finger abdomen of the patient to obtain skin electrical activity signals, and the electrophysiological signal processor 10 processes the skin electrical activity signals to form a skin electrical activity value curve which is displayed on a display of a computer 13. The skin electrical activity value can reflect the sweat gland secretion condition of a human body and indirectly reflect the activity state of sympathetic nerves, and in the acupuncture process, the body of a patient can generate the condition of whole body heating when being stimulated, so that the skin electrical activity value is also changed (usually expressed as rising), which indicates that acupuncture has influence on nerve regulation and control activity, and the influence degree can be reflected by the size of the skin electrical activity value.

The skin temperature sensor 12 is connected with the abdomen of the ring finger of the patient to obtain a skin temperature signal, and the electrophysiological signal processor 10 processes the skin temperature signal to form a skin temperature curve which is displayed on the display of the computer 13. The peripheral blood circulation condition of the human body is reflected by measuring the temperature of the abdomen of the ring finger, and whether acupuncture treatment acts on the peripheral blood circulation of the human body or not can be reflected.

The computer 13 has the functions of starting, pausing, stopping, displaying in real time, adding mark points and evaluating, wherein the starting function is that four processors including the brain blood oxygen signal processor 2, the skin blood oxygen signal processor 4, the skin blood flow signal processor 7 and the electrophysiological signal processor 10 can start to acquire related physiological signals at the same time by clicking a screen button; the pause function means that the four processors can pause to acquire physiological signals simultaneously by clicking a screen pause button; the stopping function means that the four processors can stop collecting physiological signals simultaneously by clicking a screen stopping button; the real-time display function means that the physiological signal real-time monitoring and the computer 13 can display a plurality of physiological signals collected and transmitted by the four processors in real time, wherein the physiological signals comprise a brain blood oxygen content fluctuation curve, a skin blood oxygen saturation fluctuation curve, a skin blood flow curve, a skin electrical activity value curve and a skin temperature curve which change in real time; the function of adding the mark points refers to adding event marks on the time axis of the collected multiple physiological signal curves; the evaluation function refers to that the physiological signal real-time monitoring and computer 13 can analyze and display the mean value, the variance, the maximum value and the occurrence time, and the minimum value and the occurrence time of a plurality of physiological signals among the marked points after the collection is finished.

The greatest creativity of the invention lies in that the generation of phantom limb pain is related to five parameters of cerebral blood oxygen content, skin blood oxygen saturation, skin blood flow, skin electrical activity value and skin temperature. Through a plurality of tests, when acupuncture and moxibustion is used for stimulating certain specific amputation areas, acupuncture points and meridians and collaterals of a patient with phantom limb pain, five parameters of cerebral blood oxygen content, skin blood oxygen saturation, skin blood flow, skin electrical activity values and skin temperature are changed correspondingly; furthermore, the variation trend and variation of the five parameters have a certain correlation with the improvement degree of the phantom limb pain. Therefore, the therapeutic effect of acupuncture can be evaluated according to whether the patient's phantom limb pain is effectively relieved, and the variation characteristics of the five physiological parameters.

The treatment bed 1 comprises a bed plate, a first support 21 is arranged below one end of the bed plate, a first driving mechanism for driving one end of the bed plate to lift is arranged on the first support 21, a second support 23 is arranged below the other end of the bed plate, and the second support 23 is hinged to the other end of the bed plate. The first driving mechanism comprises a first electric cylinder 24, the fixed end of the first electric cylinder 24 is hinged with the first support 21, and the telescopic end of the first electric cylinder 24 is hinged with the bed board.

The bed board and the bed board are composed of three rotating plates 20 which are connected in series, the adjacent rotating plates 20 are hinged through hinges 29, gaps are formed between the adjacent rotating plates 20, elastic bands 22 for filling the gaps are arranged between the adjacent rotating plates 20, and a second driving mechanism is arranged between the adjacent rotating plates 20. The second driving mechanism comprises a first adapter plate 25 connected with one of the adapter plates 20 and a second adapter plate 26 connected with the other adapter plate 20, a second electric cylinder 27 is arranged on the first adapter plate 25, a sphere 28 is arranged at the telescopic end of the second electric cylinder 27, and the sphere 28 is in spherical hinge with the second adapter plate 26. The elastic bands 22 are used to prevent the skin of the patient from being injured by being sandwiched between the two rotating plates 20.

The working principle of the treatment bed is as follows: the whole inclination angle of the bed plate is changed by the expansion of the first electric cylinder 24, the angle between the adjacent rotating plates 20 is changed by the expansion of the second electric cylinder 27, and the inclination angle of each rotating plate 20 can be adjusted by the first actuating cylinder and the second actuating cylinder. When a patient lies on the treatment couch 1, two rotation points (knees and crotch) of the human body are respectively located above the elastic bands 22, i.e., the head and back are on one rotating plate 20, the thighs are on the other rotating plate 20, and the calves are on the remaining rotating plates 20, and the posture of the patient on the treatment couch 1 is changed by changing the inclination angle of each rotating plate 20, thereby evaluating what kind of changes may be generated by the same acupuncture method under different postures of the patient. Through a plurality of test tests, the patient is found that when the upper end of the back of the patient is inclined downwards by 5-10 degrees, the lower end of the thigh is inclined upwards by 20-25 degrees and the lower end of the shank is inclined downwards by 40-60 degrees on a treatment bed, the stimulation effect of acupuncture stimulation can be further improved, particularly three indexes of the cerebral blood oxygen content, the skin electrical activity value and the skin temperature are obviously increased, and the method helps doctors to understand the action mechanism of acupuncture treatment on phantom limb pain.

The invention has the advantage of evaluating the influence of acupuncture on various physiological parameters of human bodies, is helpful for doctors to understand the action mechanism of acupuncture for treating phantom limb pain and provides basis.