阅读说明：本技术 一种含有猴面包树果肉提取物的抗衰老提亮组合物和抗衰老提亮精华液及其制备方法 (Anti-aging brightening composition and anti-aging brightening essence containing Paeonia suffruticosa pulp extract and preparation method thereof ) 是由 刘青 连恩杨 徐靖 谢聪 于 2021-07-29 设计创作，主要内容包括：本发明属于美容护肤技术领域,尤其涉及一种含有猴面包树果肉提取物的抗衰老提亮组合物和抗衰老提亮精华液及其制备方法。本发明所述的含有猴面包树果肉提取物的抗衰老提亮组合物包括以下组分：猴面包树果肉提取物、棕榈酰三肽-1、乙酰基六肽-8。本发明含有猴面包树果肉提取物的抗衰老提亮组合物可以强化肌肤屏障,帮助肌肤组织结构重建并减少皱纹、细纹,提亮皮肤,可作为添加剂应用于化妆品中,添加护肤品常用的机制或载体,可制成精华液、面霜、乳液等化妆品。(The invention belongs to the technical field of beauty and skin care, and particularly relates to an anti-aging brightening composition containing a Paeonia suffruticosa pulp extract, an anti-aging brightening essence and a preparation method thereof. The anti-aging brightening composition containing the Adansonia dubia pulp extract comprises the following components: the extract comprises Palmaria Adinandra pulp extract, palmitoyl tripeptide-1 and acetyl hexapeptide-8. The anti-aging brightening composition containing the Adansonia dubia pulp extract can strengthen skin barriers, help skin tissue structure reconstruction, reduce wrinkles and fine lines and brighten skin, can be applied to cosmetics as an additive, and can be prepared into cosmetics such as essence, cream, emulsion and the like by adding a common mechanism or a carrier of skin care products.)

1. An anti-aging and brightening composition containing an extract of the pulp of Adansonia dubia, characterized by comprising the following components: the extract comprises Palmaria Adinandra pulp extract, palmitoyl tripeptide-1 and acetyl hexapeptide-8.

2. The anti-aging lightening composition comprising extract of the pulp of Adansonia dubia according to claim 1, comprising the following components: an aqueous solution of Paeonia suffruticosa pulp extract (5%), an aqueous solution of palmitoyl tripeptide-1 (100ppm), and an aqueous solution of acetyl hexapeptide-8 (500 ppm).

3. The anti-aging and brightening composition containing the extract of the fruit flesh of the Adansonia dubia of claim 2, comprising the following components in parts by weight: 5-25 parts of an aqueous solution (5%) of the extract of the fruit flesh of the Paeonia suffruticosa, 1 part of an aqueous solution (100ppm) of palmitoyl tripeptide-1, 1 part of an aqueous solution (500ppm) of acetyl hexapeptide-8, and the balance of water.

4. An article of manufacture comprising the anti-aging lightening composition of any one of claims 1 to 3, wherein the anti-aging lightening composition is present in the article of manufacture in an amount of 0.1 to 10% by weight.

5. The article of claim 4, wherein the anti-aging lightening composition is present in an amount of 6 wt%.

6. The article according to claim 4, characterized in that it is selected from skincare or cosmetic products.

7. The anti-aging brightening essence is characterized by comprising the following components:

A. the anti-aging lightening composition of any one of claims 1 to 3;

B. an oil phase component;

C. an aqueous phase component;

D. a neutralizer component;

E. and (3) an auxiliary component.

8. The anti-aging brightening essence of claim 7, comprising the following components:

A. the anti-aging lightening composition of any one of claims 1 to 3;

B. oil phase components:

hydrogenated lecithin,

Cyclic polydimethyl siloxane,

Polydimethylsiloxane;

C. water phase components:

glycerin, glycerin,

1, 2-butanediol,

Pentanediol, a,

EDTA disodium salt,

Sodium acrylate/sodium acryloyldimethyl taurate copolymer,

Betaine,

Carbomer,

Water;

D. the components of a neutralizer:

triethanolamine;

E. auxiliary agent components:

phenoxyethanol,

And (4) essence.

9. The anti-aging brightening essence of claim 8, characterized by comprising the following components in parts by weight:

A. 0-10 parts of the anti-aging lightening composition of any one of claims 1 to 3;

B. oil phase components:

0.5 to 1.5 portions of hydrogenated lecithin,

1.25-2.5 parts of cyclopolydimethylsiloxane,

1.25-2.5 parts of polydimethylsiloxane;

F. water phase components:

1-5 parts of glycerol,

1-1.5 parts of 1, 2-butanediol,

1-2 parts of pentanediol,

0.05 part of EDTA disodium,

0.1 to 0.3 portion of sodium acrylate/acryloyl dimethyl taurate copolymer,

1-1.5 parts of betaine,

0.15 portion of carbomer,

The balance of water;

G. the components of a neutralizer:

0.1-0.5 part of triethanolamine;

H. auxiliary agent components:

0.5 part of phenoxyethanol,

0.1 part of essence.

10. The method for preparing the anti-aging brightening essence of any one of claims 7 to 9, comprising the steps of:

(1) heating the phase C to 80 ℃, keeping the temperature to 80 ℃, and stirring to dissolve completely;

(2) heating the phase B to 80 ℃, and stirring to dissolve completely;

(3) pumping the phase C into an emulsifying pot, slowly pumping the phase B into the emulsifying pot, homogenizing for 5 minutes, preserving heat, stirring for 10 minutes, and vacuumizing for cooling;

(4) cooling to 55 deg.C, adding phase D, homogenizing for 3 min, and stirring;

(5) adding A, E phase when the temperature is reduced to 50 ℃, keeping the temperature and stirring for 3 minutes, vacuumizing and reducing the temperature;

(6) cooling to 35 ℃ to obtain the anti-aging brightening essence.

Technical Field

The invention belongs to the technical field of beauty and skin care, and particularly relates to an anti-aging brightening composition containing a Paeonia suffruticosa pulp extract, an anti-aging brightening essence and a preparation method thereof.

Background

The Paeonia suffruticosa, also known as a living tree in Africa, is a long-lived tree species that is thought to survive for more than 2000 years. The Palmaria Adinosa pulp extract mainly contains saccharide, oil, protein, cellulose and a large amount of vitamin C, and has excellent antioxidant and anti-aging effects.

With the rapid development of society, more and more people want to seek improvement of life quality. People pay more and more attention to the problems of aging, aging and darkness of facial skin, and hope to solve the problems of aging, aging and darkness of facial skin by using an anti-aging product. Therefore, it is necessary to produce a safe product with anti-aging and brightening functions.

Disclosure of Invention

Aiming at the related technical requirements, the invention provides an anti-aging brightening composition containing a Palmaria Adanserina pulp extract, which can strengthen the skin barrier, help the skin tissue structure to rebuild, reduce wrinkles and fine lines and brighten the skin.

In order to achieve the purpose, the invention adopts the following technical scheme:

an anti-aging and lightening composition comprising extract of the pulp of Adansonia dubia, comprising the following components: the extract comprises Palmaria Adinandra pulp extract, palmitoyl tripeptide-1 and acetyl hexapeptide-8.

In the present invention, the anti-aging lightening component is a main functional additive. Wherein:

the Palmaria Adinosa pulp extract mainly contains saccharide, oil, protein, cellulose and a large amount of vitamin C, and has excellent antioxidant and anti-aging effects.

Palmitoyl tripeptide-1 is a small molecule peptide with high specificity and bioactivity. Can penetrate dermis, stimulate proliferation of collagen, elastic fiber and hyaluronic acid, increase water content and water locking degree of skin, increase skin thickness and reduce fine lines.

Acetyl hexapeptide-8 is a bioactive polypeptide that reduces muscle contraction by inhibiting the release of the neurotransmitter acetylcholine, thereby achieving a reduction in the production of dynamic and expression striations. The acetyl hexapeptide-8 can reduce the existing facial wrinkles and can effectively prevent the generation of new wrinkles.

The anti-aging brightening composition containing the Adansonia dubia pulp extract can strengthen skin barriers, help skin tissue structure reconstruction, reduce wrinkles and fine lines and brighten skin, can be applied to cosmetics as an additive, and can be prepared into cosmetics such as essence, cream, emulsion and the like by adding a common mechanism or a carrier of skin care products.

Preferably, the anti-aging and brightening composition containing the Adansonia dubia pulp extract comprises the following components: an aqueous solution of Paeonia suffruticosa pulp extract (5%), an aqueous solution of palmitoyl tripeptide-1 (100ppm), and an aqueous solution of acetyl hexapeptide-8 (500 ppm).

Preferably, the anti-aging brightening composition containing the Adinandra millettii pulp extract comprises the following components in parts by weight: 5-25 parts of an aqueous solution (5%) of the extract of the fruit flesh of the Paeonia suffruticosa, 1 part of an aqueous solution (100ppm) of palmitoyl tripeptide-1, 1 part of an aqueous solution (500ppm) of acetyl hexapeptide-8, and the balance of water.

An article of manufacture comprising the anti-aging lightening composition of any one of the preceding claims, wherein the article of manufacture comprises 0.1 to 10 wt% of the anti-aging lightening composition. The product is selected from skin care products or cosmetics such as essence, face cream, eye cream, emulsion and the like.

The invention also discloses anti-aging brightening essence which comprises the following components in parts by weight:

A. 0-10 parts of the anti-aging lightening composition of any one of claims 1 to 3;

B. oil phase components:

0.5 to 1.5 portions of hydrogenated lecithin,

1.25-2.5 parts of cyclopolydimethylsiloxane,

1.25-2.5 parts of polydimethylsiloxane;

F. water phase components:

1-5 parts of glycerol,

1-1.5 parts of 1, 2-butanediol,

1-2 parts of pentanediol,

0.05 part of EDTA disodium,

0.1 to 0.3 portion of sodium acrylate/acryloyl dimethyl taurate copolymer,

1-1.5 parts of betaine,

0.15 portion of carbomer,

The balance of water;

G. the components of a neutralizer:

0.1-0.5 part of triethanolamine;

H. auxiliary agent components:

0.5 part of phenoxyethanol,

0.1 part of essence.

The invention also discloses a preparation method of the anti-aging brightening essence, which comprises the following steps:

(1) heating the phase C to 80 ℃, keeping the temperature to 80 ℃, and stirring to dissolve completely;

(2) heating the phase B to 80 ℃, and stirring to dissolve completely;

(3) pumping the phase C into an emulsifying pot, slowly pumping the phase B into the emulsifying pot, homogenizing for 5 minutes, preserving heat, stirring for 10 minutes, and vacuumizing for cooling;

(4) cooling to 55 deg.C, adding phase D, homogenizing for 3 min, and stirring;

(5) adding A, E phase when the temperature is reduced to 50 ℃, keeping the temperature and stirring for 3 minutes, vacuumizing and reducing the temperature;

(6) cooling to 35 ℃ to obtain the anti-aging brightening essence.

Advantageous effects

The anti-aging brightening composition prepared by the invention can effectively remove excessive free radicals in vivo, strengthen skin barriers, help tissue structure reconstruction, relieve wrinkles, remove melanin and brighten skin. The anti-aging brightening composition uses natural safe components, and does not cause irritation to skin and generate adverse reaction. In addition, the dosage form of the anti-aging brightening composition containing the Adansonia dubia pulp provided by the invention is not limited, and the anti-aging brightening composition can be applied to cosmetics and skin care products in all dosage forms such as cream, essence, emulsion and the like.

Detailed Description

Hereinafter, the present invention will be described in detail. Before the description is made, it should be understood that the terms used in the present specification and the appended claims should not be construed as limited to general and dictionary meanings, but interpreted based on the meanings and concepts corresponding to technical aspects of the present invention on the basis of the principle that the inventor is allowed to define terms appropriately for the best explanation. Accordingly, the description proposed herein is just a preferable example for the purpose of illustrations only, not intended to limit the scope of the invention, so it should be understood that other equivalents and modifications could be made thereto without departing from the spirit and scope of the invention.

The following examples are given by way of illustration of embodiments of the invention and are not to be construed as limiting the invention, and it will be understood by those skilled in the art that modifications may be made without departing from the spirit and scope of the invention. Unless otherwise specified, reagents and equipment used in the following examples are commercially available products.

Example 1

An anti-aging brightening composition containing a Palmaria championii pulp extract comprises the following components in parts by mass: 5 parts of 5% aqueous solution of the extract of the fruit pulp of the Adina panorana, 1 part of aqueous solution (100ppm) of palmitoyl tripeptide-1, 1 part of aqueous solution (500ppm) of acetyl hexapeptide-8 and the balance of water.

Example 2

An anti-aging brightening composition containing a Palmaria championii pulp extract comprises the following components in parts by mass: 10 parts of 5% aqueous solution of the extract of the fruit pulp of the Adina rubescens, 1 part of palmitoyl tripeptide-1 aqueous solution (100ppm), 1 part of acetyl hexapeptide-8 aqueous solution (500ppm) and the balance of water.

Example 3 parts

An anti-aging brightening composition containing a Palmaria championii pulp extract comprises the following components in parts by mass: 15 parts of 5% aqueous solution of the extract of the fruit pulp of the Adina mulosa, 1 part of palmitoyl tripeptide-1 (100ppm), 1 part of acetyl hexapeptide-8 (500ppm) and the balance of water.

Example 4

An anti-aging brightening composition containing a Palmaria championii pulp extract comprises the following components in parts by mass: 20 parts of 5% aqueous solution of the extract of the fruit pulp of the Adina europaea, 1 part of palmitoyl tripeptide-1 (100ppm), 1 part of acetyl hexapeptide-8 (500ppm) and the balance of water.

Example 5

An anti-aging brightening composition containing a Palmaria championii pulp extract comprises the following components in parts by mass: 25 parts of 5% aqueous solution of the extract of the fruit pulp of the Adina rubescens, 1 part of palmitoyl tripeptide-1 (100ppm), 1 part of acetyl hexapeptide-8 (500ppm) and the balance of water.

Example 6

Essence 1 to 8 containing the anti-aging and lightening composition according to the present invention was prepared using the raw material components and weight percentages shown in table 1.

TABLE 1 anti-aging and brightening essence 1-8 ingredient table

Experimental example 1 DPPH radical scavenging test

Respectively preparing 0.01mg/mL aqueous solution of the anti-aging brightening essence 1-8 prepared in the example 6 by using deionized water, transferring 2mL into a 10mL test tube with a plug, taking 0.15g of DPPH (1, 1-diphenyl-2-trinitrophenylhydrazine) powder, taking 1000mL of ethanol to prepare solution, uniformly mixing, stirring in the dark at the rotation speed of 250rpm for 12 hours at normal temperature, taking 2mL of DPPH solution into the test tube with the plug, standing for 30 minutes at room temperature, and then measuring the absorbance A with the wavelength of 517nm by using a spectrophotometer₅₁₇(ii) a Simultaneously, the absorbance A of 2mL of the solution dissolved in the example mixed with 2mL of ethanol was measured₀Absorbance C after 2mL of water mixed with 2mL of DPPH ethanol solution and absorbance C after 2mL of water mixed with 2mL of ethanol solution₀. The measurements were performed in triplicate and averaged to calculate the free radical clearance according to the following formula, the greater the clearance, the greater the antioxidant capacity of the examples.

DPPH radical scavenging ratio (%) - (A)₅₁₇-A₀)/(C-C₀)]×100％

The results are shown in Table 2.

TABLE 2 DPPH radical scavenging test results of anti-aging brightening essence

As can be seen from table 2, the anti-aging lightening essence 4 prepared from example 6 has the best DPPH radical scavenging rate, i.e., the best anti-oxidation effect. The optimum addition amount of the anti-aging brightening composition in the cosmetics is 6 wt% according to the DPPH free radical clearance rate results of the anti-aging brightening essences 4, 6 and 7, and the anti-aging brightening essence 8 is the anti-aging brightening essence prepared only from basic components, and has no obvious DPPH free radical clearance effect.

Experimental example 2 wrinkle removal test

The test population: 70 healthy female volunteers between the ages of 30-50 are divided into seven groups according to the ages, 10 persons in each group have the average age of 35 +/-3 years.

The experimental method comprises the following steps: 1-8 (about 1mL) of the anti-aging brightening essence prepared in example 6 was used in the canthus crow's feet area; it is administered in the morning and evening for 4 weeks. The depth and length reduction of wrinkles and fine lines in the crow's feet area were evaluated using the face imaging system Vi sa-CR, and the results are shown in table 3.

TABLE 3 wrinkle test results recording Table

As can be seen from the test results in table 3, the obtained anti-aging lightening essence 4 was most reduced in wrinkles and fine lines in the anti-aging lightening composition configured in example 6. The results of 4, 6 and 7 show that the anti-aging brightening essence provided by the invention is optimally added into the cosmetics in an amount of 6 wt%. After the anti-aging brightening essence provided by the invention is continuously used, the quantity of wrinkles and fine lines can be obviously reduced, and the skin aging can be delayed.

Experimental example 3 skin lightening experiment

The skin color difference test probe and the multifunctional skin test system (CL400 and MPA9) are adopted to test the change of the skin brightness ITA DEG before and after the anti-aging and brightening essence prepared by the invention is used by a test subject, the ITA DEG is the skin individual type angle, and is a test for representing the skin brightness related to L, a and b. The greater the ITA value, the brighter and whiter the skin; conversely, the darker the skin.

The test population: the test person was required to be the same as in experimental example 2.

The results of the experiment are shown in table 4.

TABLE 4 skin brightness change recording sheet

As can be seen from table 4, the anti-aging brightening essence 4 has an optimal brightening effect on skin brightness, and when the anti-aging brightening composition prepared in example 4 is prepared in the essence at a higher concentration, the obtained skin brightening effect is obvious, but the adverse reactions such as allergy and the like occur in a tested population, and the proportion of the anti-aging brightening composition in the anti-aging brightening essence should be properly reduced for safety.

The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that various changes may be made and equivalents may be substituted for elements thereof; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions.