阅读说明：本技术 普瑞巴林内酰胺亚甲基二聚物及其制备方法 (Pregabalin lactam methylene dimer and preparation method thereof ) 是由 林金生 刘晓飞 李丹 王静 李月 朱文泉 陈文斌 李敏 于 2018-11-06 设计创作，主要内容包括：本申请提供了普瑞巴林内酰胺亚甲基二聚物及其制备方法,该方法包括将普瑞巴林溶解于在反应溶剂中,在酸性体系下与醛反应并经分离得到目标产物普瑞巴林内酰胺亚甲基二聚物。本申请所提供的普瑞巴林内酰胺亚甲基二聚物制备方法收率操作简单,产品收率高、纯度好并且成本低。(The method comprises the steps of dissolving pregabalin in a reaction solvent, reacting with aldehyde under an acid system, and separating to obtain a target product pregabalin lactam methylene dimer. The preparation method of the pregabalin lactam methylene dimer, provided by the application, has the advantages of simple yield operation, high product yield, good purity and low cost.)