阅读说明：本技术 充气膜结构病毒检测实验室、生物安全实验室、覆土结构病毒检测实验室 (Aerated film structure virus detection laboratory, biological safety laboratory and soil covering structure virus detection laboratory ) 是由 苏运升 尹烨 陈堃 陈戊荣 李若羽 李雯琪 王知然 曾昊 于 2020-04-16 设计创作，主要内容包括：一种充气膜结构病毒检测实验室、生物安全实验室、覆土结构病毒检测实验室。该实验室包括：充气膜结构,充气膜结构在充气后能形成洁净区、缓冲单元、高污染区；入口设备集成模块包括入口门；出口设备集成模块包括垃圾传递箱；还包括双向热交换新风机,可使高污染区为负压环境。通过设置入口和出口设备集成模块,可实现实验室的模块化设计,有利于对设备进行集中化管理,且充气膜结构通过充气可形成屋体或管状体,有利于实现充气膜结构病毒检测实验室的快速搭建,使充气膜结构病毒检测实验室尽快投入使用；此外,高污染区为负压环境,有利于保证检测病毒时的使用安全性。(An aerated membrane structure virus detection laboratory, a biological safety laboratory and an earth covering structure virus detection laboratory. The laboratory includes: the inflatable membrane structure can form a clean area, a buffer unit and a high-pollution area after being inflated; the inlet device integration module includes an inlet door; the outlet device integration module comprises a garbage transfer box; the device also comprises a bidirectional heat exchange fresh air fan, so that a high-pollution area can be in a negative pressure environment. The modular design of a laboratory can be realized by arranging the inlet and outlet equipment integrated module, the centralized management of equipment is facilitated, and the inflatable membrane structure can form a room body or a tubular body by inflating, so that the rapid construction of the inflatable membrane structure virus detection laboratory is facilitated, and the inflatable membrane structure virus detection laboratory can be put into use as soon as possible; in addition, the high pollution area is in a negative pressure environment, so that the use safety in virus detection is guaranteed.)

1. An air-filled membrane structure virus detection laboratory, comprising: an inflatable membrane structure (1) which can be inflated to form a house body or a tubular body;

the inflatable membrane structure (1) can form a functional space (19) after being inflated, a clean area (2), one or more buffer units (3) used as auxiliary functional areas and a high pollution area (4) used as a main functional area are arranged in the functional space (19), the buffer units (3) are limited by the inflatable membrane structure (1), the buffer units (3) separate the clean area (2) from the high pollution area (4), and the buffer units (3) are provided with inner opening and closing doors (33) which are hermetically separated from or communicated with the clean area (2) and the high pollution area (4);

an inlet equipment integration module (5), wherein the inlet equipment integration module (5) is arranged at one end of the functional space (19) and at least comprises an inlet door (51), and the inlet door (51) is hermetically isolated from or communicated with the clean area (2);

an outlet device integration module (6), the outlet device integration module (6) being arranged at the other end of the functional space (19) and comprising at least a waste transfer bin (61);

at least one of the inlet device integrated module (5) and the outlet device integrated module (6) further comprises a bidirectional heat exchange fresh air fan with a filtering device for delivering gas to the functional space (19) or withdrawing gas from the functional space (19);

by means of the bidirectional heat exchange fresh air fan, the high pollution area (4) can be in a negative pressure environment.

2. The air-filled membrane structure virus detection laboratory according to claim 1, wherein the buffer unit (3) and the clean area (2) are both in a negative pressure environment, and the pressure relationship among the clean area (2), the buffer unit (3) and the high pollution area (4) is as follows: the clean zone (2) > the buffer unit (3) > the high-pollution zone (4).

3. The air-filled membrane structure virus detection laboratory of claim 2, further comprising: at least one air column air pipe (71) with one end extending into the functional space (19), and the other end of the air column air pipe (71) is connected with the corresponding bidirectional heat exchange fresh air machine.

4. The air-filled membrane structure virus detection laboratory according to claim 3, wherein a first air duct opening communicated with the clean zone (2), a second air duct opening communicated with the buffer unit (3) and a third air duct opening communicated with the highly polluted zone (4) are formed in the air column air duct (71).

5. The air-filled membrane structure virus detection laboratory according to claim 1, wherein said bi-directional heat exchange ventilator comprises: an inlet side bidirectional heat exchange fresh air fan (52) belonging to the inlet equipment integration module (5) and an outlet side bidirectional heat exchange fresh air fan (62) belonging to the outlet equipment integration module (6).

6. The air-filled membrane structure virus detection laboratory according to claim 5, wherein at least one of the inlet device integration module (5) and the outlet device integration module (6) further comprises an outdoor unit of an air conditioner, and an indoor unit (72) of an air conditioner is disposed in the functional space (19).

7. The laboratory for detecting viruses of claim 6, wherein said outdoor unit of air conditioner comprises: an inlet side air conditioning outdoor unit (53) belonging to the inlet device integration module (5) and an outlet side air conditioning outdoor unit (63) belonging to the outlet device integration module (6).

8. The air-filled membrane structure virus detection laboratory according to claim 7, wherein said inlet device integration module (5) further comprises: and an inlet equipment frame (54), wherein the inlet side outdoor air conditioner unit (53) and the inlet side bidirectional heat exchange fresh air fan (52) are placed on the inlet equipment frame (54).

9. The air-filled membrane structure virus detection laboratory according to claim 8, wherein said inlet device integration module (5) further comprises: a sterilizing and disinfecting sump (55), the sterilizing and disinfecting sump (55) being placed on the inlet equipment rack (54).

10. The air-filled membrane structure virus detection laboratory according to claim 1, wherein the entrance door (51) is an intelligent interactive entrance door, and the entrance door (51) is opened and closed in a non-contact manner.

11. The air-filled membrane structure virus detection laboratory according to claim 7, wherein said outlet device integration module (6) further comprises: and the garbage transfer box (61), the outlet side air conditioner outdoor unit (63) and the outlet side bidirectional heat exchange fresh air fan (62) are placed on the outlet equipment frame (64).

12. The air-filled membrane structure virus detection laboratory according to claim 1, wherein said outlet device integration module (6) further comprises: the fire-fighting escape emergency door (65), wherein the fire-fighting escape emergency door (65) is hermetically separated from or communicated with the high pollution area (4).

13. Gas-filled membrane structure virus detection laboratory according to claim 1, characterized in that at least one of the zones clean (2), buffer (3), high contamination (4) is provided with a smoke alarm system.

14. Air-filled membrane structure virus detection laboratory according to claim 1, characterized in that at least one area of the clean zone (2), the buffer unit (3), the high contamination zone (4) is provided with a dry powder fire extinguisher.

15. Air-filled membrane structure virus detection laboratory according to claim 1, characterized in that one or more air disinfection devices (73) are provided inside said high contamination zone (4), said air disinfection devices (73) comprising: any one or combination of a plurality of plasma disinfectors, ultraviolet ozonizers and dry fog type hydrogen peroxide sterilizers.

16. The air-filled membrane structure virus detection laboratory according to claim 1, wherein the buffer unit (3) comprises: a first changing room (31) and a second changing room (32) independent from each other, the first changing room (31) and the second changing room (32) each having the inner opening/closing door (33).

17. The air-filled membrane structure virus detection laboratory according to claim 16, wherein an inlet passage is formed among the inlet door (51), the inner opening door (33) between the first changing room (31) and the clean zone (2), and the inner opening door (33) between the first changing room (31) and the high-contamination zone (4), and an outlet passage is formed among the inner opening door (33) between the second changing room (32) and the high-contamination zone (4), the inner opening door (33) between the second changing room (32) and the clean zone (2), and the inlet door (51).

18. The air-filled membrane structure virus detection laboratory according to claim 1, wherein the opening and closing manner of the inner opening and closing door (33) comprises: any one or combination of a plurality of zippers, magnetic adsorption, sticking, hooks and buckles.

19. The laboratory for detecting viruses of pneumatic membrane structures according to claim 1, wherein a lighting strip (74) is arranged in the functional space (19), and the lighting strip (74) is fixed on the pneumatic membrane structure (1) through a magic tape and/or a bandage.

20. The inflatable membrane structure virus detection laboratory according to claim 1, wherein the inflatable membrane structure (1) comprises an inflatable membrane dome structure and an inflatable membrane isolation structure, the functional space (19) being defined by the inflatable membrane dome structure after inflation, and the buffer unit (3) being defined by the inflatable membrane isolation structure.

21. The aerated film structure virus detection laboratory of claim 20, wherein the aerated film dome structure comprises: a plurality of closely arranged arch-shaped air inflation rings (14), and the air inflation rings (14) are air inflation rings (14) with positive pressure air film space (17) inside.

22. The air-filled membrane structure virus detection laboratory according to claim 21, characterized in that the inside of the air-filled ring (14) is covered with a single membrane (13).

23. The aerated film structure virus detection laboratory of claim 20, wherein the aerated film dome structure comprises: the support frame (15) that are located the outside and be located inboard single membrane (13) or bilayer membrane, single membrane (13) be suitable for with form between support frame (15) and be full of the air film space (17) of malleation, the bilayer membrane is the bilayer membrane that has malleation air film space (17) inside.

24. The aerated film structure virus detection laboratory of claim 20, wherein the aerated film dome structure comprises: support gas column frame (16), support gas column frame (16) are built by many inside support gas columns (161) that have positive pressure gas film space (17) and form, just the outside of supporting gas column frame (16) covers single-layer film (13) or has the bilayer membrane of positive pressure gas film space (17).

25. The laboratory for detecting viruses in an inflatable membrane structure according to claim 1, wherein the inflatable membrane structure (1) has a membrane space (17) and a membrane structure filling port and a membrane structure air outlet (18) which are communicated with the membrane space (17), the air blower is communicated with the membrane structure filling port and blows air into the membrane space (17), and the air inlet amount at the membrane structure filling port is greater than the air outlet amount at the membrane structure air outlet (18), so that the membrane space (17) is a positive pressure membrane space.

26. The gas-filled membrane structure virus detection laboratory according to claim 1, characterized in that the high-pollution zone (4) is provided with a humidifier to meet humidity requirements; and/or one or more skylights are arranged at the top of the high pollution area (4) for lighting or ventilation, and an inward unidirectional filtering device is arranged at each skylight.

27. Air-filled membrane structure virus detection laboratory according to any one of claims 1 to 26, characterized in that the high contamination zone (4) has a first transfer port (41) and a second transfer port (42), where a transfer unit is adapted to be arranged at the first transfer port (41) and the second transfer port (42).

28. The air-filled membrane structure virus detection laboratory according to claim 27, wherein the transfer unit is a material transfer box and/or a personnel access box.

29. The air-filled membrane structure virus detection laboratory according to claim 28, wherein each of the transfer unit and the garbage transfer box (61) comprises an inner door facing the high pollution area (4) and an outer door facing the outside, and each of the transfer unit and the garbage transfer box (61) adopts intelligent interaction technology, so that the inner door and the outer door form an intelligent interlocking structure to ensure that the inner door and the outer door cannot be opened simultaneously.

30. The inflatable membrane structure virus detection laboratory according to claim 28, wherein the inflatable membrane structure (1) is collapsible for storage by gas extraction.

31. The laboratory for detecting viruses in aerated film structures according to claim 28, wherein the outer surface of the aerated film structure (1) can be upgraded or modified into a permanent structure by spraying any one or more of construction industry materials, pouring concrete, and covering vegetation.

32. A biosafety laboratory, comprising: a plurality of air-filled membrane structure virus detection laboratories as claimed in any one of claims 27 to 31, wherein the second transfer port (42) of one air-filled membrane structure virus detection laboratory is aligned with the first transfer port (41) of an adjacent one of the air-filled membrane structure virus detection laboratories and is connected by the transfer unit.

33. The biosafety laboratory according to claim 32, wherein there are two inflatable membrane virus detection laboratories, and the second transfer port (42) of the first inflatable membrane virus detection laboratory (10) is aligned with the first transfer port (41) of the second inflatable membrane virus detection laboratory (20) and connected by the transfer unit.

34. The biosafety laboratory according to claim 33, wherein said highly contaminated zone (4) of said first air-filled membrane structure virus detection laboratory (10) is a sample receiving and preparation zone and said highly contaminated zone (4) of said second air-filled membrane structure virus detection laboratory (20) is an amplification zone.

35. The biosafety laboratory according to claim 34, wherein the first transfer port (41) of the first air-filled membrane structure virus detection laboratory (10) is a first sample inlet, and the second transfer port (42) of the second air-filled membrane structure virus detection laboratory (20) is a second sample inlet.

36. The biosafety laboratory according to claim 35, wherein a sample inactivation zone, a sample unpacking and information verification zone, a sample tube rotating plate zone and a sample preparation zone are arranged in the high-pollution zone (4) of the first air-filled membrane structure virus detection laboratory (10) so as to meet the requirements of a sample receiving and preparation process.

37. The biosafety laboratory according to claim 36, characterized in that a drying oven (101) is provided at said sample inactivation zone, wherein the sample is inactivated within said drying oven (101); a first biological safety cabinet (102) is arranged at the sample unpacking and information verification area, and the sample is unpacked and information verified in the first biological safety cabinet (102); a second biological safety cabinet (103) is arranged at the sample tube rotating plate area, and a sample tube is rotated in the second biological safety cabinet (103); a sample nucleic acid extractor (104) is disposed at the sample preparation area for automated extraction of sample nucleic acid.

38. The biosafety laboratory according to claim 33 or 37, wherein any one or more of a centrifuge (81), a refrigerator (82), a printer (83) and a vibrator (84) are further arranged in the high-pollution zone (4) of the first air-filled membrane structure virus detection laboratory (10).

39. The biosafety laboratory according to claim 37, characterized in that said drying box (101) is arranged adjacent to said first sample inlet.

40. The biosafety laboratory according to claim 37, characterized in that a nucleic acid amplification instrument (201) is arranged in the high-pollution area (4) of the second air-filled membrane structure virus detection laboratory (20) to satisfy the amplification process of the sample.

41. The biosafety laboratory according to claim 33 or 40, wherein any one or more of a centrifuge (81), a refrigerator (82) and a shaker (84) are further arranged in the high-pollution zone (4) of the second air-filled membrane structure virus detection laboratory (20).

42. The biosafety laboratory according to claim 40, characterized in that said drying cabinet (101), said first biosafety cabinet (102), said second biosafety cabinet (103), said sample nucleic acid extractor (104), said nucleic acid amplifier (201) are used in sequence.

43. The biosafety laboratory according to claim 33, characterized in that said highly contaminated zone (4) of said first and second air-filled membrane structure virus detection laboratories (10, 20) is further provided with an autoclave (85) for sterilizing medical waste.

44. The biosafety laboratory according to claim 34, characterized in that the side of the first air-filled membrane structure virus detection laboratory (10) facing away from the second air-filled membrane structure virus detection laboratory (20) is provided with at least one first auxiliary air-filled membrane structure virus detection laboratory for assisting the sample receiving and preparation process;

at least one second auxiliary inflatable membrane structure virus detection laboratory for assisting an amplification process is arranged on one side, away from the first inflatable membrane structure virus detection laboratory (10), of the second inflatable membrane structure virus detection laboratory (20);

the first auxiliary inflatable membrane structure virus detection laboratory and the second auxiliary inflatable membrane structure virus detection laboratory are both the inflatable membrane structure virus detection laboratory.

45. An earth-covered structure virus detection laboratory, comprising: the virus detection laboratory of any one of claims 1 to 31, wherein the outer surface of the inflatable membrane structure (1) is formed by spraying any one or more of construction industry materials, pouring concrete and covering vegetation, so that the virus detection laboratory of the inflatable membrane structure becomes a permanent covering structure building.

46. An earth-covered structure virus detection laboratory, comprising: the biosafety laboratory of any one of claims 32 to 44, wherein said outer surface of said aerated membrane structure (1) is constructed by any one or more of spraying construction industry materials, pouring concrete, and covering vegetation to make said biosafety laboratory a permanent earthing structure.

Technical Field

The utility model relates to a building field is kept apart in the protection, particularly relates to an aerify membrane structure virus and detect laboratory, have the above-mentioned biological safety laboratory who aerifys membrane structure virus and detect the laboratory, have the above-mentioned earthing structure virus that aerifys membrane structure virus and detect the laboratory, have the earthing structure virus detection laboratory of above-mentioned biological safety laboratory.

Background

In addition to the great demand for epidemic prevention hospitals, shelter hospitals and isolation places in China after the outbreak of a large-scale epidemic situation in China in the early 2020, a virus detection laboratory (or a biological safety laboratory) for virus detection and research has serious defects.

A bio-safety laboratory is a laboratory built by standard laboratory design, configuration of experimental equipment, use of individual protective equipment, and the like. When sudden epidemic situations or related events occur, relevant samples (including human bodies, animals, environments and the like) collected on site are rapidly sent to a biological safety protection laboratory for detection and identification (detection) of potential biological risk factors (pathogens, toxins and the like) so as to effectively support site scientific decision and rapid response.

Most of traditional virus detection laboratories adopt traditional prefabricated building structures, and need to provide an indoor negative pressure system to treat polluted air, so that the problems of high implementation cost, long construction period, difficulty in dismantling after construction, incapability of being packaged and stored in advance, difficulty in site selection and the like are caused. When the virus epidemic situation is outbreak on a large scale, the traditional virus detection laboratory or the traditional biological safety laboratory can obviously not meet the flexible and timely construction requirement.

Therefore, a virus detection site which can be fast, simple and meet higher biological safety level is needed.

Disclosure of Invention

The present application aims to solve at least to some extent one of the above-mentioned technical problems of the prior art. For this reason, this application provides an aerify membrane structure virus detection laboratory, integrates the higher and can realize putting up fast of degree.

The application also provides a biological safety laboratory with the gas-filled membrane structure virus detection laboratory.

This application has provided the earthing structure virus detection laboratory who aerifys membrane structure virus detection laboratory again of one kind above-mentioned.

The application provides an earthing structure virus detection laboratory who has above-mentioned biological safety laboratory again.

An air-filled membrane structure virus detection laboratory according to an embodiment of the first aspect of the present application comprises: the inflatable membrane structure which can form a house body or a tubular body by inflation; the inflatable membrane structure can form a functional space after being inflated, and the functional space is internally provided with a clean area, one or more buffer units used as auxiliary functional areas and a high-pollution area used as a main functional area, wherein the buffer units are limited by the inflatable membrane structure, the buffer units separate the clean area from the high-pollution area, and the buffer units are provided with inner opening and closing doors which are hermetically separated from or communicated with the clean area and the high-pollution area; the inlet equipment integration module is arranged at one end of the functional space and at least comprises an inlet door, and the inlet door is hermetically separated from or communicated with the clean area; the outlet equipment integration module is arranged at the other end of the functional space and at least comprises a garbage transfer box; at least one of the inlet equipment integration module and the outlet equipment integration module further comprises a bidirectional heat exchange fresh air fan with a filtering device, wherein the bidirectional heat exchange fresh air fan is used for conveying gas to the functional space or extracting gas from the functional space; by means of the bidirectional heat exchange fresh air fan, the high-pollution area can be in a negative pressure environment.

According to the inflatable membrane structure virus detection laboratory, the modular design of the laboratory can be realized by arranging the inlet equipment integration module and the outlet equipment integration module, centralized management of equipment is facilitated, and the inflatable membrane structure can form a room body or a tubular body by inflating, so that the inflatable membrane structure virus detection laboratory can be quickly built, and the inflatable membrane structure virus detection laboratory can be put into use as soon as possible; in addition, the high pollution area is in a negative pressure environment, so that the use safety in virus detection is guaranteed.

According to some embodiments of the present application, the buffer unit and the clean area are both in a negative pressure environment, and the pressure relationship among the clean area, the buffer unit and the high pollution area is as follows: the clean area is larger than the buffer unit and is larger than the high-pollution area.

According to some embodiments of the present application, the aerated membrane structure virus detection laboratory further comprises: and at least one air column air pipe with one end extending into the functional space, wherein the other end of the air column air pipe is connected with the corresponding bidirectional heat exchange fresh air fan.

Furthermore, a first air pipe opening communicated with the clean area, a second air pipe opening communicated with the buffer unit and a third air pipe opening communicated with the high-pollution area are formed in the air column air pipe.

According to some embodiments of the application, the bidirectional heat exchange fresh air machine comprises: an inlet side bidirectional heat exchange fresh air fan belonging to the inlet equipment integration module and an outlet side bidirectional heat exchange fresh air fan belonging to the outlet equipment integration module.

Further, at least one of the inlet device integration module and the outlet device integration module further comprises an air conditioner outdoor unit, and an air conditioner indoor unit is arranged in the functional space.

Specifically, the outdoor unit of an air conditioner includes: an inlet side air conditioner outdoor unit belonging to the inlet device integration module and an outlet side air conditioner outdoor unit belonging to the outlet device integration module.

Further, the inlet device integration module further comprises: and the inlet side air conditioner outdoor unit and the inlet side bidirectional heat exchange fresh air fan are arranged on the inlet equipment frame.

According to some embodiments of the present application, the inlet device integration module further comprises: and the sterilizing sewage tank is placed on the inlet equipment frame.

According to some embodiments of the application, the entrance door is a smart interactive entrance door, and the entrance door is opened and closed in a non-contact manner.

According to some embodiments of the present application, the exit device integration module further comprises: and the garbage transfer box, the outlet side air conditioner outdoor unit and the outlet side bidirectional heat exchange fresh air machine are placed on the outlet equipment frame.

According to some embodiments of the present application, the exit device integration module further comprises: and the fire-fighting escape emergency door is hermetically separated or communicated with the high-pollution area.

According to some embodiments of the present application, at least one area of the clean zone, the buffer unit, the high contamination zone is provided with a smoke alarm system.

According to some embodiments of the present application, at least one area of the clean zone, the buffer unit, the high contamination zone is provided with a dry powder fire extinguisher.

According to some embodiments of the application, one or more air disinfection devices are disposed within the high contamination zone, the air disinfection devices comprising: any one or combination of a plurality of plasma disinfectors, ultraviolet ozonizers and dry fog type hydrogen peroxide sterilizers.

According to some embodiments of the present application, the buffer unit includes: the first dressing room and the second dressing room are independent of each other, and the inner opening and closing door is arranged in each of the first dressing room and the second dressing room.

Furthermore, an inlet channel is formed among the inlet door, the inner opening and closing door between the first changing room and the clean area, and the inner opening and closing door between the first changing room and the high-pollution area, and an outlet channel is formed among the inlet door, the inner opening and closing door between the second changing room and the high-pollution area, the inner opening and closing door between the second changing room and the clean area, and the inlet door.

According to some embodiments of the present application, the opening and closing manner of the inner opening and closing door comprises: any one or combination of a plurality of zippers, magnetic adsorption, sticking, hooks and buckles.

According to some embodiments of the application, be provided with the light area in the functional space, the light area passes through the magic subsides and/or the bandage is fixed on the membrane structure of aerifing.

According to some embodiments of the present application, the inflatable membrane structure comprises an inflatable membrane dome structure and an inflatable membrane isolation structure, the functional space is defined by the inflatable membrane dome structure after inflation, and the cushioning unit is defined by the inflatable membrane isolation structure.

According to some embodiments of the present application, the inflatable membrane dome structure comprises: a plurality of closely arranged arch-shaped air inflation rings, just the air inflation ring is the air inflation ring that has the positive pressure air film space inside.

Further, the inner side of the air filled ring is covered with a single layer film.

According to some embodiments of the present application, the inflatable membrane dome structure comprises: the single-layer film is suitable for forming a positive-pressure air film space between the support frames, and the double-layer film is a double-layer film with a positive-pressure air film space inside.

According to some embodiments of the present application, the inflatable membrane dome structure comprises: support gas column frame, support gas column frame is built by many inside support gas columns that have malleation air film space and is formed, just the outside of supporting gas column frame covers the single-layer film or has the bilayer membrane in malleation air film space.

According to some embodiments of this application, aerify the membrane structure have the air film space and with membrane structure fill mouth and membrane structure air outlet of membrane space intercommunication, the air-blower with membrane structure fill mouthful be linked together and to blast air in the air film space, the intake of membrane structure fill mouth department is greater than the air output of membrane structure air outlet department, so that the air film space is malleation air film space.

According to some embodiments of the present application, the high contamination zone is provided with a humidifier to meet humidity requirements; and/or one or more skylights are arranged at the top of the high pollution area for lighting or ventilation, and an inward unidirectional filtering device is arranged at each skylight.

According to some embodiments of the present application, the high contamination zone has a first transfer port and a second transfer port, the first transfer port and the second transfer port being adapted for arranging a transfer unit.

Optionally, the transfer unit is a material transfer box and/or a personnel access box.

According to some embodiments of the application, the transfer unit the rubbish transfer box all include towards the interior door in high contamination district and towards outside outer door, the transfer unit the rubbish transfer box all adopts intelligent interaction technique, makes interior door with outer door forms intelligent interlocking structure, in order to ensure that interior door with outer door can not open simultaneously.

According to some embodiments of the application, the inflatable membrane structure enables folding stowing by gas extraction.

According to some embodiments of the present application, the outer surface of the inflatable membrane structure can be upgraded or modified into a permanent structure by any one or more of spraying construction industry materials, pouring concrete, and covering vegetation.

A biosafety laboratory according to an embodiment of the second aspect of the application, comprising: a plurality of air-filled membranous virus detection laboratories as described in embodiments of the first aspect of the present application, wherein the second transfer port of one air-filled membranous virus detection laboratory is aligned with the first transfer port of an adjacent one of said air-filled membranous virus detection laboratories and connected by said transfer unit.

According to some embodiments of the present application, the number of the air-filled membrane structure virus detection laboratories is two, and the second transfer port of the first air-filled membrane structure virus detection laboratory is aligned with the first transfer port of the second air-filled membrane structure virus detection laboratory and connected through the transfer unit.

According to some embodiments of the present application, the high-contamination zone of the first air-filled membrane structure virus detection laboratory is a sample receiving and preparation zone, and the high-contamination zone of the second air-filled membrane structure virus detection laboratory is an amplification zone.

According to some embodiments of the present application, the first transfer port of the first air-filled membrane structure virus detection laboratory is a first sample inlet, and the second transfer port of the second air-filled membrane structure virus detection laboratory is a second sample inlet.

Specifically, a sample inactivation area, a sample unpacking and information verification area, a sample tube rotating plate area and a sample preparation area are arranged in the high-pollution area of the first laboratory for detecting viruses with aerated membrane structures, so as to meet the requirements of the receiving and preparation processes of the samples.

Further, a drying box is arranged at the sample inactivation area, and the sample is inactivated in the drying box; a first biological safety cabinet is arranged in the sample unpacking and information verifying area, and unpacking and information verifying are carried out on the sample in the first biological safety cabinet; a second biological safety cabinet is arranged at the sample tube rotating plate area, and a sample tube is rotated in the second biological safety cabinet; and a sample nucleic acid extractor is arranged at the sample preparation area and used for automatically extracting sample nucleic acid.

Optionally, any one or more combinations of a centrifuge, a refrigerator, a printer and a vibrator are further arranged in the high-pollution area of the first air-filled membrane structure virus detection laboratory.

Optionally, the drying box is disposed adjacent to the first sample inlet.

According to some embodiments of the present application, a nucleic acid amplification instrument is disposed in the high-contamination area of the second air-filled membrane structure virus detection laboratory to satisfy the amplification process of the sample.

Optionally, any one or more of a centrifuge, a refrigerator and a shaker are further arranged in the high-pollution area of the second air-filled membrane structure virus detection laboratory.

According to some embodiments of the present application, the drying oven, the first biosafety cabinet, the second biosafety cabinet, the sample nucleic acid extractor, the nucleic acid amplifier are used sequentially.

Optionally, an autoclave for sterilizing medical waste is further arranged in the high-pollution area of the first air-filled membrane structure virus detection laboratory and the second air-filled membrane structure virus detection laboratory.

According to some embodiments of the present application, a side of the first air-filled membrane structure virus detection laboratory facing away from the second air-filled membrane structure virus detection laboratory is provided with at least one first auxiliary air-filled membrane structure virus detection laboratory for assisting in sample receiving and preparation processes;

at least one second auxiliary inflatable membrane structure virus detection laboratory for assisting an amplification process is arranged on one side of the second inflatable membrane structure virus detection laboratory, which is far away from the first inflatable membrane structure virus detection laboratory;

the first auxiliary inflatable membrane structure virus detection laboratory and the second auxiliary inflatable membrane structure virus detection laboratory are both the inflatable membrane structure virus detection laboratory.

According to the biosafety laboratory of the embodiment of the second aspect of the present application, the functional regions are physically separated by the transfer unit, which is beneficial to improve the safety of the biosafety laboratory, for example, in case of leakage of nucleic acid diffused in the amplification region, the leaked nucleic acid can be prevented from entering the sample receiving and preparation region.

According to the third aspect of the application, the virus detection laboratory of the casing structure comprises: according to the virus detection laboratory with the inflatable membrane structure, the outer surface of the inflatable membrane structure is formed into a long-lasting soil covering structure building by spraying any one or more of building industrial materials, pouring concrete and covering vegetation.

According to this application fourth aspect embodiment's earthing structure virus detection laboratory includes: the biosafety laboratory according to the embodiment of the second aspect of the present application, the outer surface of the inflatable membrane structure is formed by any one or more of spraying construction industry materials, pouring concrete and covering vegetation, so that the biosafety laboratory becomes a permanent covering soil structure building.

Additional aspects and advantages of the present application will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the present application.

Drawings

FIG. 1 is a schematic diagram of a biosafety laboratory;

FIG. 2 is a schematic view of a biosafety laboratory with the gas-filled membrane structure removed;

FIG. 3 is a schematic internal view of a biosafety laboratory;

FIG. 4 is a schematic cross-sectional view of a first embodiment of an inflatable membrane dome structure;

FIG. 5 is a schematic cross-sectional view of a second embodiment of an inflatable membrane dome structure;

FIG. 6 is a schematic cross-sectional view of a third embodiment of an inflatable membrane dome structure;

FIG. 7 is a top view of a third embodiment of an inflatable membrane dome structure;

FIG. 8 is a schematic representation of the streamlines of a stream of people for a biosafety laboratory;

FIG. 9 is a schematic flow diagram of the equipment of the biosafety laboratory;

FIG. 10 is a schematic of the material flow lines of the biosafety laboratory;

fig. 11 is a schematic view of another embodiment of a biosafety laboratory.

Reference numerals:

the air-inflated membrane structure 1, the inner membrane 11, the outer membrane 12, the single-layer membrane 13, the air-inflated ring 14, the support frame 15, the support air column frame 16, the support air column 161, the air membrane space 17, the membrane structure air outlet 18, the functional space 19, the clean area 2, the buffer unit 3, the first changing room 31, the second changing room 32, the inner opening and closing door 33, the high pollution area 4, the first transfer opening 41, the second transfer opening 42, the intermediate material transfer box 43, the feeding transfer box 44, the personnel passage box 45, the entrance equipment integration module 5, the entrance door 51, the entrance side bidirectional heat exchange fresh air fan 52, the entrance side air conditioner outdoor unit 53, the entrance equipment frame 54, the disinfection and sterilization sewage box 55, the blower frame 56, the exit equipment integration module 6, the garbage transfer box 61, the exit side bidirectional heat exchange fresh air fan 62, the exit side air conditioner outdoor unit 63, the exit equipment frame 64, the fire escape emergency door 65, the air column 71, the air duct 72, the, The device comprises an air disinfection device 73, a lighting strip 74, a centrifuge 81, a refrigerator 82, a printer 83, an oscillator 84, an autoclave 85, a first air-filled membrane structure virus detection laboratory 10, a drying box 101, a first biosafety cabinet 102, a second biosafety cabinet 103, a sample nucleic acid extractor 104, a second air-filled membrane structure virus detection laboratory 20 and a nucleic acid amplification instrument 201.

Detailed Description

Reference will now be made in detail to embodiments of the present application, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary and intended to be used for explaining the present application and should not be construed as limiting the present application.

In this application, unless expressly stated or limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can include, for example, fixed connections, removable connections, or integral parts; can be mechanically connected, electrically connected or can communicate with each other; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art as appropriate.

The building system with the inflatable membrane structure is an innovative construction technology developed in the years, is high in construction speed and cost performance, convenient to store daily, high in volume compression ratio and transport, convenient to allocate resources among various cities, and convenient to use an existing production system to produce and construct on a large scale in time.

An air-filled membrane structure virus detection laboratory according to an embodiment of the present application is described in detail below with reference to fig. 1 to 11.

Referring to fig. 1-3, an air-filled membrane structure virus detection laboratory according to an embodiment of the first aspect of the present application may include: the inflatable membrane structure 1, the inlet device integration module 5 and the outlet device integration module 6, which are inflated to form a house body or a tubular body, are provided.

Referring to fig. 2-3, the inflatable membrane structure 1 can form a functional space 19 after being inflated, and an experimenter can perform virus detection work and other auxiliary work (such as replacing protective clothing and the like) in the functional space 19. The inflatable membrane structure 1 can be formed after being inflated, which is beneficial to quickly building the functional space 19. For areas with large detection quantity, the detection pressure can be greatly relieved in a short time by using an inflatable membrane structure virus detection laboratory which can be built and molded quickly. In addition, the inflatable membrane structure 1 can be removed after being deflated, so that after the detection task is completed, the virus detection laboratory of the inflatable membrane structure can be removed to release the space.

Referring to fig. 2-3, a clean area 2, a high-pollution area 4, one or more buffer units 3 are arranged in the functional space 19, and the buffer units 3 are used as auxiliary functional areas, for example, the replacement of protective clothing can be performed in the buffer units 3; the high contamination zone 4 is used as a main functional area, and for example, the receiving, preparation, amplification, etc. of the sample can be operated in the high contamination zone 4.

Referring to fig. 3, the buffer unit 3 may be defined by the inflatable membrane structure 1, the buffer unit 3 separating the clean zone 2 from the highly contaminated zone 4, and the buffer unit 3 having an inner opening-closing door 33 in airtight partition or communication with the clean zone 2 and the highly contaminated zone 4. Thereby realizing the physical isolation of the three areas of the clean area 2, the buffer unit 3 and the high pollution area 4.

As shown in fig. 1 to 3, the inlet equipment integrated module 5 is disposed at one end of the functional space 19, and the inlet equipment integrated module 5 includes at least an inlet door 51, and the inlet door 51 is hermetically isolated from or communicated with the clean zone 2.

In a specific embodiment, the entrance door 51 may be a single-layer door, and when the entrance door 51 is opened, the clean zone 2 may communicate with the outside; when the entrance door 51 is closed, the clean zone 2 may be isolated from the outside.

In other alternative embodiments, the access door 51 may be a double door, and the double door includes an inner door and an outer door, in which case the access door 51 may be configured as a smart interactive access door, such as a light interactive access door, such that the inner door and the outer door are intelligently interlocked, i.e., the inner door and the outer door are configured to be incapable of being opened simultaneously, so as to isolate the clean zone 2 from the outside. For example, when the inner door of the entrance door 51 is opened and the outer door is closed, the inner space of the entrance door 51 communicates with the clean zone 2 and is isolated from the outside; when the outer door of the entrance door 51 is opened and the inner door is closed, the inner space of the entrance door 51 communicates with the outside and is isolated from the clean zone 2.

As shown in fig. 1 to 3, the outlet device integration module 6 is provided at the other end of the functional space 19, and the outlet device integration module 6 includes at least a trash receptacle 61. The waste generated in the functional space 19 can be transferred from the waste transfer box 61 to the outside after being sterilized.

At least one of the inlet device integrated module 5 and the outlet device integrated module 6 further comprises a bidirectional heat exchange fresh air fan with a filtering device, the bidirectional heat exchange fresh air fan is used for supplying air to the functional space 19 or extracting air from the functional space 19, that is, the bidirectional heat exchange fresh air fan can realize air suction and air supply functions. The number of the bidirectional heat exchange fresh air fans can be set to be multiple, and the working modes can also have multiple combination modes, for example, when one part of the bidirectional heat exchange fresh air fans pump air out of the functional space 19, the other part of the bidirectional heat exchange fresh air fans convey air to the functional space 19; or all the two-way heat exchange fresh air fans simultaneously supply air to the functional space 19 for a period of time, and then switch to simultaneously extract air from the functional space 19, and the air supply and extraction can be alternately performed.

Through the action of air suction and air supply of the bidirectional heat exchange fresh air fan, the directional flow of air can be formed inside the functional space 19, and the bidirectional heat exchange fresh air fan is provided with the filtering device, so that an air inlet and an air outlet are efficiently filtered, the phenomenon that substances such as dust and particles in the outside air are brought into the functional space 19 is avoided, the phenomenon that viruses in the functional space 19 are brought to the outside is also avoided, and the high use safety of an inflatable membrane structure virus detection laboratory is ensured.

The high pollution area 4 can be in a negative pressure environment by means of the bidirectional heat exchange fresh air fan. For example, when the amount of gas delivered to the highly polluted region 4 by the two-way heat exchange fresh air fan is smaller than the amount of gas extracted from the highly polluted region 4 by the two-way heat exchange fresh air fan, the inside of the highly polluted region 4 is in a negative pressure environment. By setting the high pollution zone 4 to a negative pressure environment, pathogenic microorganisms in the high pollution zone 4 can be effectively prevented from diffusing into the external environment.

In some optional embodiments, the amount of gas delivered to the high pollution area 4 by the bidirectional heat exchange fresh air fan is larger than the amount of gas extracted from the high pollution area 4 by the bidirectional heat exchange fresh air fan, and at this time, a positive pressure environment exists in the high pollution area 4.

Alternatively, the Filter device may be a multi-layer HEPA (High efficiency particulate air Filter) High efficiency Filter screen, which is a Filter screen meeting the HEPA standard, and has an effective rate of 99.7% for 0.1 micron and 0.3 micron, and the HEPA screen is characterized in that air can pass through but fine particles cannot pass through. It can remove more than 99.97% of particles with diameter of 0.3 micrometer (1/200 of hair diameter), and is the most effective filtering medium for smoke, dust and bacteria. HEPA divides five materials of PP filter paper, glass fiber, compound PP PET filter paper, melt-blown polyester non-woven fabrics and melt-blown glass fiber. The method is characterized in that: the wind resistance is large, the dust holding capacity is large, the filtering precision is high, the filter can be processed into various sizes and shapes according to the requirements of customers, and the filter is suitable for different machine types.

According to the inflatable membrane structure virus detection laboratory provided by the embodiment of the application, the modular design of the inflatable membrane structure virus detection laboratory can be realized by arranging the inlet equipment integration module 5 and the outlet equipment integration module 6, equipment on the inlet side is integrated in the inlet equipment integration module 5, equipment on the outlet side is integrated in the outlet equipment integration module 6, centralized management of the equipment is facilitated, the shape of the laboratory is concise and attractive, a room body or a tubular body can be formed by inflating the inflatable membrane structure 1, quick building of the inflatable membrane structure virus detection laboratory is facilitated, the time consumed by the inflatable membrane structure virus detection laboratory from building to use is greatly shortened, and the inflatable membrane structure virus detection laboratory can be put into use as soon as possible; in addition, the high pollution area 4 is a negative pressure environment, which is beneficial to ensuring the use safety when detecting viruses, so that the laboratory can meet the corresponding biological safety level specification.

In some embodiments, the high contamination area 4, the buffer unit 3 and the clean area 2 are all negative pressure environments, that is, negative pressure environments are provided in the functional space 19, so that when the entrance door 51 is opened and the clean area 2 is communicated with the outside, air flows only from the outside to the clean area 2, and air in the clean area 2 does not flow to the outside, which is beneficial to improving the use safety performance of the laboratory for detecting viruses in an inflatable membrane structure.

The clean area 2, the buffer unit 3 and the high pollution area 4 form an air pressure difference, and the pressure relationship among the clean area 2, the buffer unit 3 and the high pollution area 4 is as follows: the clean area 2 is larger than the buffer unit 3 and is larger than the high-pollution area 4, namely the negative pressure of the clean area 2 is the weakest, and the negative pressure of the high-pollution area 4 is the strongest. Thus, when the clean area 2 is communicated with the buffer unit 3, air flows from the clean area 2 with a relatively low negative pressure to the buffer unit 3, but cannot flow from the buffer unit 3 to the clean area 2, and the phenomenon that the clean area 2 is polluted because the air in the buffer unit 3 flows to the clean area 2 is avoided. And when the buffer unit 3 is communicated with the high pollution area 4, the air flows from the buffer unit 3 with weak negative pressure to the high pollution area 4 only, but cannot flow from the high pollution area 4 to the buffer unit 3, so that the problem that unclean gas in the high pollution area 4 flows to the buffer unit 3 to cause the buffer unit 3 to be polluted is avoided. The negative pressure at the high pollution area 4 is strongest, so that the outward diffusion of pathogenic microorganisms in the high pollution area 4 can be effectively prevented, and the use safety performance of an aerated membrane structure virus detection laboratory can be further improved.

Referring to fig. 2, the gas-filled membrane structure virus detection laboratory may further include: at least one air column air pipe 71 with one end extending into the functional space 19, and the other end of the air column air pipe 71 is connected with a corresponding bidirectional heat exchange fresh air fan.

Furthermore, a first air duct opening communicated with the clean area 2, a second air duct opening communicated with the buffer unit 3 and a third air duct opening communicated with the high pollution area 4 are formed in the air column air duct 71. When the bidirectional heat exchange fresh air machine works, the air can be conveyed to the corresponding clean area 2, the buffer unit 3 and the high pollution area 4 through the first air pipe opening, the second air pipe opening and the third air pipe opening on the air column air pipe 71, or the air can be pumped out from the corresponding clean area 2, the buffer unit 3 and the high pollution area 4.

The air column air pipes 71 correspond to the bidirectional heat exchange fresh air fans one by one.

In the present application, the terms "first", "second" and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implying any number of technical features indicated. Thus, features defined as "first", "second", "third" may explicitly or implicitly include one or more of the features. In the description of the present application, "plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.

In the embodiment of fig. 1-2, the bi-directional heat exchange fresh air machine may include: an inlet side bidirectional heat exchange fresh air fan 52 belonging to the inlet equipment integration module 5 and an outlet side bidirectional heat exchange fresh air fan 62 belonging to the outlet equipment integration module 6. As shown in fig. 2, the inlet-side bidirectional heat exchange fresh air fan 52 is connected to the inlet-side air column duct 71, and the outlet-side bidirectional heat exchange fresh air fan 62 is connected to the outlet-side air column duct 71.

In some embodiments, the inlet side bi-directional heat exchange ventilator 52 may be configured as a ventilator that delivers air to the functional space 19 and the outlet side bi-directional heat exchange ventilator 62 may be configured as a ventilator that withdraws air from the functional space 19. The two-way heat exchange fresh air fan 52 on the inlet side and the two-way heat exchange fresh air fan 62 on the outlet side may be provided in plural, so as to improve the air suction and supply efficiency.

Further, at least one of the inlet device integration module 5 and the outlet device integration module 6 further includes an outdoor unit of an air conditioner, and an indoor unit 72 of the air conditioner is disposed in the functional space 19. The outdoor unit and the indoor unit 72 constitute an air conditioning system for adjusting the temperature in the functional space 19.

Specifically, as shown in fig. 1 to 2, the outdoor unit of an air conditioner includes: an inlet side air conditioner outdoor unit 53 belonging to the inlet device integration module 5 and an outlet side air conditioner outdoor unit 63 belonging to the outlet device integration module 6.

Further, the inlet device integration module 5 further includes: an inlet equipment rack 54, an inlet side outdoor unit 53, and an inlet side bidirectional heat exchange fresh air fan 52 are placed on the inlet equipment rack 54.

As shown in fig. 2, the inlet device integration module 5 further includes: and the sterilizing and disinfecting sewage tank 55, wherein the sterilizing and disinfecting sewage tank 55 is placed on the inlet equipment frame 54. The inlet equipment rack 54 may be constructed as a multi-layered rack, whereby the inlet side air conditioner outdoor unit 53, the inlet side bidirectional heat exchange fresh air fan 52, and the disinfecting and sterilizing sewage tank 55 may be arranged in layers, for example, the inlet side bidirectional heat exchange fresh air fan 52 may be arranged at the uppermost layer, facilitating the connection of the inlet side bidirectional heat exchange fresh air fan 52 with the air column duct 71; the sterilizing and disinfecting waste water tank 55 is heavy and can be arranged at the bottommost layer to ensure good placing stability. Meanwhile, the layered arrangement is beneficial to saving space and further realizing the integrated design of a laboratory.

Optionally, the entrance door 51 is a smart interactive entrance door, and the entrance door 51 is opened and closed in a non-contact manner. Thus, the laboratory worker can enter and exit the entrance door 51 without touching the entrance door 51. In some alternative embodiments, the entrance door 51 may be a light interactive entrance door, and the entrance door 51 is opened or closed by means of a flashlight of a mobile phone or a flashing ring. In other alternative embodiments, the entrance door 51 may also be a voice interactive entrance door, and the opening or closing of the entrance door 51 is realized by voice instructions. In this way, it is ensured that contactless control of the entrance door 51 can be achieved without using face scanning even when the laboratory worker wears the protective clothing.

As shown in fig. 2, the outlet device integration module 6 further includes: the outlet equipment frame 64, the waste transfer box 61, the outlet side outdoor air conditioner 63 and the outlet side two-way heat exchange fresh air fan 62 are placed on the outlet equipment frame 64. The outlet equipment rack 64 may be constructed as a multi-layer rack, whereby the garbage transfer box 61, the outlet side air conditioner outdoor unit 63, and the outlet side bidirectional heat exchange fresh air fan 62 may be arranged in layers, for example, the outlet side bidirectional heat exchange fresh air fan 62 may be arranged at the uppermost layer, facilitating the connection of the outlet side bidirectional heat exchange fresh air fan 62 with the air column duct 71; the waste transfer box 61 can be disposed at the bottommost layer due to frequent use, and can prevent the waste passing through the waste transfer box 61 from falling on the outlet side outdoor air conditioner 63 and the outlet side bidirectional heat exchange fresh air fan 62. Meanwhile, the layered arrangement is beneficial to saving space and further realizing the integrated design of a laboratory.

Referring to fig. 2-3, 8, the outlet device integration module 6 further includes: the fire-fighting escape emergency door 65 and the fire-fighting escape emergency door 65 are hermetically separated from or communicated with the high pollution area 4. When a dangerous condition occurs in the high pollution area 4, the experimenter can realize quick escape through the fire escape emergency door 65. The escape streamline is shown as B streamline in FIG. 8.

In some embodiments, at least one of the clean area 2, the buffer unit 3 and the high pollution area 4 is provided with a smoke alarm system, for example, the smoke alarm system can be arranged in the high pollution area 4, and the smoke alarm system can also be arranged in three areas of the clean area 2, the buffer unit 3 and the high pollution area 4. Through being equipped with smog alarm system, can play the warning effect when the condition of a fire takes place in the laboratory to promote the fire control security performance who aerifys membrane structure virus detection laboratory, guarantee its safety in utilization.

In some embodiments, at least one of the clean area 2, the buffer unit 3 and the high-pollution area 4 is provided with a dry powder fire extinguisher, for example, the dry powder fire extinguisher may be provided in the high-pollution area 4, or the dry powder fire extinguisher may be provided in three areas of the clean area 2, the buffer unit 3 and the high-pollution area 4. Through being equipped with the dry powder fire extinguisher, can put out the small fire, prevent that the intensity of a fire from stretching to further promote the fire control security performance who aerifys membrane structure virus detection laboratory, guarantee its safe in utilization.

As shown in fig. 3, one or more air sterilizing devices 73 are disposed in the high pollution zone 4, and the air sterilizing devices 73 include: any one or combination of a plurality of plasma disinfectors, ultraviolet ozonizers and dry fog type hydrogen peroxide sterilizers. Through setting up air degassing unit 73, can reduce the content of harmful air in high pollution zone 4, from the personal safety of guaranteeing the experiment personnel in high pollution zone 4. The air disinfection device 73 may be a uv vehicle so that the air disinfection device 73 may move freely within the high contamination zone 4 to facilitate disinfection of the air in the respective zones.

As shown in fig. 3, the buffer unit 3 includes: the first and second changerooms 31 and 32 are independent of each other, and each of the first and second changerooms 31 and 32 has an inner opening/closing door 33.

Further, as shown in fig. 3 and 8, an entrance door 51, an inner opening/closing door 33 between the first changing room 31 and the clean area 2, and an entrance passage are formed between the first changing room 31 and the inner opening/closing door 33 between the high-contamination area 4, and an exit passage is formed between the second changing room 32 and the high-contamination area 4, and an inner opening/closing door 33 between the second changing room 32 and the clean area 2, and an entrance door 51. The personnel flow line of the laboratory personnel at the aerated membrane structure virus detection laboratory can be shown as flow line a in fig. 8, namely: the experimenter enters the high pollution area 4 through the entrance door 51, the inner opening and closing door 33 between the first changing room 31 and the clean area 2, the first changing room 31, the inner opening and closing door 33 between the first changing room 31 and the high pollution area 4, and then exits through the inner opening and closing door 33 between the second changing room 32 and the high pollution area 4, the second changing room 32, the inner opening and closing door 33 between the second changing room 32 and the clean area 2, and the entrance door 51.

The first changing room 31 is positioned in the inlet passage, and an experimenter can replace the pollution-free protective clothing in the first changing room 31; the second changing room 32 is located in the exit passage, and the laboratory worker can take off the contaminated protective clothing in the second changing room 32.

Optionally, the opening and closing manner of the inner opening and closing door 33 includes: the combination of any one or more of zip fastener, magnetic force absorption, paste, couple, buckle, these open and shut the mode simple, convenient, help the experimenter to open fast and close interior door 33 that opens and shuts to this intercommunication time that reduces between buffer unit 3 and the clean district 2, the intercommunication time between buffer unit 3 and the high contaminated district 4.

Referring to fig. 2, a lighting strip 74 is disposed in the functional space 19, and the lighting strip 74 is fixed on the inflatable membrane structure 1 by a hook and loop fastener and/or a strap. In the embodiment shown in fig. 2, the light strip 74 is configured as an arched strip, and the arched strip follows the inner surface of the inflatable membrane structure 1, thereby increasing the aesthetic appearance of the light strip 74. In some embodiments, not shown, the light strip 74 may be configured in other shapes, such as a linear strip, and extend along the length of the air-filled membrane virus detection laboratory to increase the length of the light strip 74 and extend the illumination range.

In some embodiments, the inflatable membrane structure 1 comprises an inflatable membrane dome structure and an inflatable membrane insulation structure, the functional space 19 being defined by the inflatable membrane dome structure after inflation, and the cushioning unit 3 being defined by the inflatable membrane insulation structure. The inflatable membrane isolation structure may be connected to, or independent of, the air membrane space 17 within the inflatable membrane dome structure.

In the embodiment shown in fig. 1, 4, the inflatable membrane dome structure comprises: a plurality of closely packed arch-shaped air filled rings 14, and the air filled ring 14 is the air filled ring 14 with a positive pressure air film space 17 inside. In other words, the gas film space 17 inside the gas filled ring 14 is a positive pressure environment, which ensures that the gas filled ring 14 has a greater rigidity and can support outside the functional space 19, so that the spatial shape of the functional space 19 is maintained.

Referring to fig. 4, the air ring 14 includes an inner membrane 11 and an outer membrane 12, and an air membrane space 17 is formed between the inner membrane 11 and the outer membrane 12. Preferably, the membrane spaces 17 within each of the inflatable rings 14 are independent of each other so that, after a failure of one of the inflatable rings 14, the other inflatable rings 14 can be used without requiring immediate replacement of the entire inflatable membrane structure 1 and repair of the failed inflatable ring 14 can be performed for continued use. Of course, the film spaces 17 of adjacent plural air-filled rings 14 may be communicated with each other.

Further, the inner side of the inflatable ring 14 is covered with the single-layer film 13, the single-layer film 13 shields the inflatable ring 14 from the inner side, the inner surface of the single-layer film 13 is flat, and a gap between two adjacent inflatable rings 14 is avoided, so that the top of the functional space 19 is flat, the defect that the appearance is not attractive due to the fact that a gap between two adjacent inflatable rings 14 is exposed is avoided, and meanwhile, the single-layer film 13 can enable the inflatable film dome structure to have better sealing performance.

In the embodiment shown in fig. 5(a), the inflatable membrane dome structure comprises: a support frame 15 positioned at the outer side and a single-layer film 13 positioned at the inner side, wherein an air film space 17 filled with positive pressure is formed between the single-layer film 13 and the support frame 15. The supporting frame 15 can be a multi-section supporting frame, the single-layer film 13 is attached to the edge of each section of the supporting frame, the middle of each section of the supporting frame is separated, and gas is filled between the single-layer film 13 and each section of the supporting frame, so that the inflatable film dome structure has the performances of heat preservation, heat insulation and the like. Meanwhile, a plurality of air film spaces 17 are formed between the single-layer film 13 and each section of the supporting frame, and when one air film space 17 is damaged, other air film spaces 17 can be used normally.

In the embodiment shown in fig. 5(b), the inflatable membrane dome structure comprises: the double-layer film is a double-layer film, a positive pressure air film space 17 is arranged in the double-layer film, and the supporting frame 15 is limited on the outer side of the double-layer film and plays a limiting role in the double-layer film.

The double layer membrane comprises an inner membrane 11, an outer membrane 12, the outer membrane 12 being located outside the inner membrane 11, and an air membrane space 17 being formed between the inner membrane 11 and the outer membrane 12. The support frame 15 can be a multi-section support frame, the outer film 12 of the double-layer film is suitable for being attached to each section of support frame, and the double-layer film can enable the inflatable film dome structure to have the performances of heat preservation, heat insulation and the like. Meanwhile, the air film spaces 17 may be divided into a plurality of spaces, and when one air film space 17 is damaged, the other air film spaces 17 can be used normally.

The support frame 15 may be a steel frame, or a frame structure such as a plastic frame or a composite frame, which can support.

In the embodiment shown in fig. 6-7, the inflatable membrane dome structure comprises: and a supporting air column frame 16, wherein the supporting air column frame 16 is formed by building a plurality of supporting air columns 161 with positive pressure air film spaces 17 inside, and the outer side of the supporting air column frame 16 is covered with a single-layer film 13 or a double-layer film with the positive pressure air film spaces 17. The supporting air column frame 16 can play a role in supporting the single-layer film 13 or the double-layer film, and the single-layer film 13 or the double-layer film is covered on the outer side of the supporting air column frame 16, so that the inflatable membrane dome structure has the performances of heat preservation, heat insulation and the like, and has good sealing performance. In some embodiments, there are multiple support air columns 161, and when one support air column 161 is damaged, the other support air columns 161 can be used normally.

The inner membrane 11, the outer membrane 12, the single-layer membrane 13, and the support air column 161 may be made of the same membrane material.

Referring to fig. 1, 3-5, the inflatable membrane structure 1 has a membrane space 17, and a membrane structure filling opening and a membrane structure air outlet 18 which are communicated with the membrane space 17, the blower is communicated with the membrane structure filling opening and blows air into the membrane space 17, and the air inlet amount at the membrane structure filling opening is larger than the air outlet amount at the membrane structure air outlet 18, so that the membrane space 17 is a positive pressure membrane space. The blower may be mounted on a blower frame 56 as shown in fig. 2, and the blower frame 56 may be fixedly attached to the inlet equipment rack 54 such that the blower frame 56 becomes part of the inlet equipment integration module 5.

The film material of the inflatable film structure 1 mainly includes glass fiber cloth, plastic film, metal woven fabric, etc., among which glass fiber cloth is preferable, and the surface thereof may be coated with polytetrafluoroethylene, etc., to increase durability and fire-proof property. In addition, after the inflatable membrane structure 1 is inflated and supported, the interior of the inflatable membrane structure 1 may be sprayed with architectural coatings to enhance the stability and physical protection characteristics, enhance the isolation strength, and the like, for example, polyurethane waterproof coatings may be sprayed in the inflatable membrane structure 1 to enhance the waterproof performance.

The inflatable membrane structure 1 also has a good toughness to avoid being easily damaged during installation or use. In addition, the inflatable membrane structure 1 may be transparent or may be a dark color that can be blocked to meet different requirements. In addition, the inflatable membrane structure 1 can flexibly select inflatable membranes with different thickness degrees according to the isolation period length of the epidemic latent period or the complexity of the terrain.

In some embodiments, not shown, the inflatable membrane structure 1 comprises an inner membrane, an outer membrane, and an air membrane space formed between the inner and outer membranes. The seams of the inner film and the outer film can adopt three forms of welding, bonding, sewing and the like. In some alternative embodiments, the air film space may be a complete sealed cavity; in other alternative embodiments, the gas film space may be divided into a plurality of continuous sealed cavities; after one of the chambers is broken, the other chambers can be used continuously without replacing the entire inflatable membrane structure 1 immediately, and the broken chamber can be repaired for continuous use. And an inflation inlet is arranged on the outer membrane corresponding to each sealed cavity for pre-inflation. In short, the inflatable membrane structure 1 is provided with two layers to enhance the protection of air tightness and improve the durability.

As shown in fig. 1, the air-filled rings 14 are provided with membrane structure air outlets 18, and each air-filled ring 14 has a membrane structure air outlet 18, or a plurality of air-filled rings 14 share the same membrane structure air outlet 18.

According to some embodiments of the present application, the highly contaminated zone 4 is provided with a humidifier to ensure that the humidity within the highly contaminated zone 4 meets the humidity requirements, i.e. to ensure that the humidity within the highly contaminated zone 4 is within the range required by the specifications.

According to some embodiments of the present application, one or more louvers are disposed at the top of the high pollution area 4 for lighting or ventilation, and an inward unidirectional filtering device is disposed at the louver, so that only external air is allowed to enter the high pollution area 4 through the unidirectional filtering device, and air in the high pollution area 4 is not allowed to escape through the unidirectional filtering device, thereby effectively preventing viruses in the high pollution area 4 from leaking out. In an actual scene, the lighting and ventilation requirements of the high pollution area 4 in the actual scene can be met through the skylight.

Referring to fig. 3, the high contamination zone 4 has a first transfer port 41 and a second transfer port 42, and transfer units are adapted to be disposed at the first transfer port 41 and the second transfer port 42.

Optionally, the transfer unit is a material transfer box and/or a personnel access box 45. The number of the first transfer opening 41 and the second transfer opening 42 may be one or more, and a material transfer box or a personnel access box 45 may be disposed at the first transfer opening 41 and the second transfer opening 42, or both the material transfer box and the personnel access box 45 may be disposed at the same time.

In the embodiment shown in fig. 3, the transfer unit is a material transfer box (e.g., an intermediate material transfer box 43, a feed material transfer box 44) through which the sample, reagent, or the like may be transferred to the interior of the high contamination zone 4.

In some embodiments, not shown, the transfer unit is a personnel access box 45 for laboratory personnel to enter and exit.

In the embodiment shown in fig. 11, the transfer units are a material transfer box and a personnel access box 45, and the sample or reagent can be transferred to the inside of the high-pollution area 4 through the material transfer box, or can be carried by the experimenter and transferred to the inside of the high-pollution area 4 through the personnel access box 45.

In some embodiments, the transferring unit and the garbage transferring box 61 each include an inner door facing the high pollution area 4 and an outer door facing the outside, and the transferring unit and the garbage transferring box 61 all adopt intelligent interaction technology, so that the inner door and the outer door form an intelligent interlocking structure, and the inner door and the outer door cannot be opened simultaneously, thereby ensuring that the transferring unit and the garbage transferring box 61 can play an isolation role, and the inner side of the inner door cannot be communicated with the outer side of the outer door, so as to ensure the use safety of the gas-filled membrane virus detection laboratory. In some optional embodiments, the intelligent interaction technology may be an optical interaction technology, so that the inner door and the outer door become an optical interaction door, and the inner door and the outer door are instructed to be opened or closed by using a mobile phone flash lamp or a flashing ring. In other alternative embodiments, the inner door and the outer door may also be voice interactive doors, and the opening or closing of the inner door and the outer door is realized by using voice instructions. Thus, it is ensured that the transfer unit and the trash transfer box 61 can be controlled without using the face scan even when the test person wears the protective clothing.

In some embodiments, the inflatable membrane structure 1 enables folding stowing by gas extraction. The inflatable membrane structure 1 has high volume compression ratio, can store a large amount of folded inflatable membrane structures 1 in a limited space, can transport a large amount of folded inflatable membrane structures 1 at one time, and is favorable for realizing quick construction of a laboratory. When an epidemic situation outbreak occurs, the inflatable membrane structure virus detection laboratory can be used as a temporary building to be close to an epidemic situation outbreak place for emergency use. And after epidemic situation peak period passed, this application aerify membrane structure virus detection laboratory and can take out gas, will aerify membrane structure 1 disinfection and retrieve, make things convenient for follow-up to transfer it to new address and splice again.

The outer surface of the inflatable membrane structure 1 can be upgraded or transformed into a permanent building by spraying any one or combination of more of building industry materials, pouring concrete and covering vegetation.

Referring to fig. 3, 8-11, a biosafety laboratory according to an embodiment of the second aspect of the present application comprises: a plurality of air-filled membrane structure virus detection laboratories as described in the embodiments of the first aspect of the present application, wherein the second transfer port 42 of one air-filled membrane structure virus detection laboratory is aligned with the first transfer port 41 of an adjacent air-filled membrane structure virus detection laboratory and connected by a transfer unit.

In the embodiment shown in fig. 3, 8-10, the gas-filled membrane structure virus detection laboratories are two, namely the biosafety laboratory comprises: two air-filled membrane structure virus detection laboratories, the second delivery port 42 of the first air-filled membrane structure virus detection laboratory 10 is aligned with the first delivery port 41 of the second air-filled membrane structure virus detection laboratory 20, and the two are connected through a delivery unit. In the embodiment shown in fig. 3, the transfer unit between the second transfer port 42 of the first air-filled membrane structure virus detection laboratory 10 and the first transfer port 41 of the second air-filled membrane structure virus detection laboratory 20 is an intermediate material transfer box 43. The size of intermediate charge transfer box 43 is less, can make two aerify the distance between the membrane structure virus detection laboratory as far as possible little to reduce the space that biological safety laboratory occupied, thereby conveniently place a plurality of biological safety laboratory in limited space, thereby further improve the daily check and measure.

The high contamination zone 4 of the first air-filled membrane structure virus detection laboratory 10 is a sample receiving and preparation zone to highly integrate functions of sample receiving, sample preparation and the like, and the high contamination zone 4 of the second air-filled membrane structure virus detection laboratory 20 is an amplification zone. In the embodiment shown in FIG. 3, the nucleic acid sample prepared by the sample receiving and preparation zone can be delivered to the amplification zone via the intermediate transfer chamber 43 without requiring the laboratory personnel to access the amplification zone from the sample receiving and preparation zone.

The first transfer port 41 of the first air-filled membrane structure virus detection laboratory 10 is a first sample inlet, and the second transfer port 42 of the second air-filled membrane structure virus detection laboratory 20 is a second sample inlet. In the embodiment shown in fig. 3, the transfer units at the first and second sample inlets are feed transfer boxes 44. The material flow line of the biosafety laboratory is shown in fig. 10, and the sample collected at the sample collection area can be delivered to the first air-filled membrane structure virus detection laboratory 10 through the first sample inlet, as shown by the flow line D1 in fig. 10; reagents may be delivered into the second air-filled membrane structure virus detection laboratory 20 via the second sample inlet, as shown by the flow line D2 in fig. 10; the material flow line at the intermediate material transfer box 43 is shown as the D3 flow line in fig. 10.

The feed transfer box 44 is configured as a sterilization transfer box to improve safety in use.

Referring to fig. 3, a sample inactivation area, a sample unpacking and information verifying area, a sample tube rotating plate area and a sample preparation area are arranged in the high-pollution area 4 of the first air-filled membrane structure virus detection laboratory 10 so as to satisfy the sample receiving and preparation process.

Further, a drying box 101 is arranged at the sample inactivation area, and the sample is inactivated in the drying box 101; a first biological safety cabinet 102 is arranged at the sample unpacking and information verifying area, and the sample is unpacked and information verified in the first biological safety cabinet 102; a second biological safety cabinet 103 is arranged at the sample tube rotating plate area, and the sample tube is rotated in the second biological safety cabinet 103; a sample nucleic acid extractor 104 is provided at the sample preparation area for automated extraction of sample nucleic acid.

Optionally, any one or more of a centrifuge 81, a refrigerator 82, a printer 83 and a vibrator 84 are further arranged in the high pollution area 4 of the first air-filled membrane structure virus detection laboratory 10. The centrifuge 81 may be any one or a combination of a plate centrifuge, a palm centrifuge, and a high-speed centrifuge.

Optionally, the drying chamber 101 is disposed adjacent to the first sample inlet, whereby the sample coming from the first sample inlet can be placed in the drying chamber 101 for inactivation at a close distance, reducing the residence time of the sample in the first air-filled membrane structure virus detection laboratory 10.

The nucleic acid amplification instrument 201 is arranged in the high-pollution area 4 of the second air-filled membrane structure virus detection laboratory 20 to satisfy the amplification process of the sample. The nucleic acid amplification instrument 201 may be a fluorescence quantitative PCR instrument for realizing exponential amplification of nucleic acid.

Optionally, any one or more of a centrifuge 81, a refrigerator 82 and a shaker 84 are further disposed in the high contamination area 4 of the second air-filled membrane structure virus detection laboratory 20. The centrifuge 81 may be any one or a combination of a plate centrifuge, a palm centrifuge, and a high-speed centrifuge.

Centrifuge 81 may be used to centrifuge the sample, freezer 82 may refrigerate the sample, shaker 84 may oscillate the sample, and printer 83 may be used to print sample information, labels, etc.

Referring to fig. 3 and 9, the drying cabinet 101, the first biosafety cabinet 102, the second biosafety cabinet 103, the sample nucleic acid extractor 104, and the nucleic acid amplifier 201 are used in sequence. The plant usage flow line may be as shown by the C flow line in FIG. 9.

Optionally, an autoclave 85 for sterilizing medical waste is further disposed in the high pollution area 4 of the first and second air-filled membrane structure virus detection laboratories 10 and 20, and the sterilized waste is delivered to an external waste receiving device through the corresponding waste delivery box 61, so that it is ensured that the waste discharged from the biosafety laboratory is sterilized waste, and secondary pollution to the environment is prevented. The waste flow lines at the waste transfer box 61 are shown as E1 flow lines, E2 flow lines in fig. 10.

According to the biosafety laboratory of the embodiment of the second aspect of the application, the sample receiving and preparation area is separated from the amplification area through the transfer unit, so that the use safety of the biosafety laboratory is improved, and once the diffused nucleic acid in the amplification area leaks, the leaked nucleic acid can be prevented from entering the sample receiving and preparation area.

In the embodiment shown in fig. 11, the side of the first air-filled membrane structure virus detection laboratory 10 facing away from the second air-filled membrane structure virus detection laboratory 20 is provided with at least one first auxiliary air-filled membrane structure virus detection laboratory, such as laboratory 30, for assisting in the sample receiving and preparation process;

at least one second auxiliary gas-filled membrane structure virus detection laboratory for assisting the amplification process, such as laboratories 40 and 50, is arranged on the side of the second gas-filled membrane structure virus detection laboratory 20 away from the first gas-filled membrane structure virus detection laboratory 10;

the first auxiliary inflatable membrane structure virus detection laboratory 30 and the second auxiliary inflatable membrane structure virus detection laboratories 40 and 50 are both inflatable membrane structure virus detection laboratories. The circulation of materials or people can be realized between any two adjacent aerated membrane structure virus detection laboratories through the intermediate material transfer box 43 and/or the personnel access box 45.

Only the intermediate transfer box 43 may be provided between the first and second air-filled membrane structure virus detection laboratories 10 and 20, without the personnel access box 45, to reduce the tendency of the laboratory personnel to walk between the amplification zone of the second air-filled membrane structure virus detection laboratory 20 and the sample receiving and preparation zone of the first air-filled membrane structure virus detection laboratory 10.

An intermediate material transfer box 43 and a personnel passage box 45 can be arranged between the first aerated membrane structure virus detection laboratory 10 and the first auxiliary aerated membrane structure virus detection laboratory 30, and an intermediate material transfer box 43 and a personnel passage box 45 can be arranged between the second aerated membrane structure virus detection laboratory 20 and the second auxiliary aerated membrane structure virus detection laboratories 40 and 50.

According to the third aspect of the application, the virus detection laboratory of the casing structure comprises: according to the virus detection laboratory with the inflatable membrane structure of the embodiment of the first aspect of the application, the outer surface of the inflatable membrane structure 1 is coated with any one or more of construction industry materials, concrete pouring and vegetation covering, so that the virus detection laboratory with the inflatable membrane structure becomes a long-lasting soil covering structure building. The virus detection laboratory with the inflatable membrane structure is a single laboratory, and the virus detection laboratory with the soil covering structure, which comprises the virus detection laboratory with the inflatable membrane structure, is also a single laboratory.

According to this application fourth aspect embodiment's earthing structure virus detection laboratory includes: the outer surface of the inflatable membrane structure 1, as in the biosafety laboratory of the embodiment of the second aspect of the present application, is coated with any one or more of construction industry materials, poured concrete, and cover vegetation, so that the biosafety laboratory becomes a permanent soil-covered structure building. The biological safety laboratory is a plurality of laboratories, and the soil covering structure virus detection laboratory comprising the biological safety laboratory is also a plurality of laboratories.

According to some embodiments of the present application, the spraying or jetting of the outer surface of the inflatable membrane structure 1 may be achieved using one or more combinations of polyurethane spraying, steel fibre concrete spraying, EPS gypsum spraying, cement mortar spraying. Of course, other spraying means not mentioned in the present application may be used to spray the outer surface of the inflatable membrane structure 1.

In addition, the human flow (A, B), the material flow (D1, D2 and D3) and the garbage flow (E1 and E2) are strictly separated, so that the use safety of an aerated membrane virus detection laboratory, a biological safety laboratory and an earth covering structure virus detection laboratory is improved.

In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example" or "some examples" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the application. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples described in this specification can be combined and combined by those skilled in the art.

Although embodiments of the present application have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present application, and that variations, modifications, substitutions and alterations may be made to the above embodiments by those of ordinary skill in the art within the scope of the present application.