阅读说明：本技术 一种防侧漏抗菌卫生巾及其制备方法 (Side-leakage-preventing antibacterial sanitary towel and preparation method thereof ) 是由 李伟伟 于 2021-01-22 设计创作，主要内容包括：本发明属于卫生用品技术领域,具体是一种防侧漏抗菌卫生巾的制备方法,包括从上到下依次复合的亲肤层、导流层、棉芯层和托层,托层的两侧还设置有用于防止侧漏的护翼；亲肤层与导流层之间还设有护理层,护理层由无纺布浸泡在均匀吸附有混合药剂的卫生巾绒毛浆之后取出干燥而成；混合药剂由下列重量份的原料混合制成：茶叶提取物6～10份、果皮提取物10～14份、果肉提取物3～5份和中草药提取物6～12份。本发明可有效的延长卫生巾的保质期,同时制备的卫生巾具有消菌杀毒的效果。与现有的同类卫生巾相比,不但保留了同类卫生巾的不产生抗药性,自然施药等的优点,而且可不变卫生巾的原有性能和加工工艺,具有实际的生产的意义和价值。(The invention belongs to the technical field of sanitary articles, and particularly relates to a preparation method of an anti-side-leakage antibacterial sanitary towel, which comprises a skin-friendly layer, a flow guide layer, a cotton core layer and a support layer which are sequentially compounded from top to bottom, wherein two sides of the support layer are also provided with protective wings for preventing side leakage; a nursing layer is arranged between the skin-friendly layer and the diversion layer, and is formed by soaking non-woven fabrics in sanitary towel fluff pulp uniformly adsorbed with mixed medicament, taking out and drying; the mixed medicament is prepared by mixing the following raw materials in parts by weight: 6-10 parts of tea extract, 10-14 parts of peel extract, 3-5 parts of pulp extract and 6-12 parts of Chinese herbal medicine extract. The invention can effectively prolong the shelf life of the sanitary towel, and the prepared sanitary towel has the effects of sterilization and disinfection. Compared with the prior similar sanitary napkins, the sanitary napkins not only keep the advantages of the similar sanitary napkins such as no drug resistance, natural drug application and the like, but also can not change the original performance and processing technology of the sanitary napkins, and have the significance and value of actual production.)

1. A preparation method of an anti-side-leakage antibacterial sanitary towel is characterized by comprising a skin-friendly layer, a flow guide layer, a cotton core layer and a support layer which are sequentially compounded from top to bottom, wherein two sides of the support layer are also provided with protective wings for preventing side leakage;

a nursing layer is arranged between the skin-friendly layer and the diversion layer, and is formed by soaking non-woven fabrics in sanitary towel fluff pulp uniformly adsorbed with mixed medicament, taking out and drying;

the mixed medicament is prepared by mixing the following raw materials in parts by weight: 6-10 parts of tea extract, 10-14 parts of peel extract, 3-5 parts of pulp extract and 6-12 parts of Chinese herbal medicine extract.

2. The method for preparing an antibacterial sanitary napkin for preventing side leakage according to claim 1, wherein the method for preparing the tea extract comprises the following steps: crushing 8-15 parts of Java tea, 5-12 parts of Pu' er tea and 3-5 parts of Saina leaves to 30-70 meshes, adding deionized water in an amount which is 4-6 times the weight of the tea, performing microwave pretreatment for 10-20 min, performing water bath extraction for 30-45 min, filtering, combining the filtrates after two times of extraction, cooling to 50-60 ℃, concentrating, and performing vacuum freeze drying for 24-48 h to obtain the tea extract.

3. The method for preparing an antibacterial sanitary napkin for preventing side leakage according to claim 1, wherein the method for preparing the pericarp extract comprises the following steps: purifying, extracting and drying 3-5 parts of pomegranate peel and 15-25 parts of gamboge peel, then crushing to 80-100 meshes, adding deionized water in an amount which is 6-8 times the weight of pomegranate peel, carrying out countercurrent extraction for 30-60 min at an ultrasonic frequency of 50-100 KHz and a temperature of 30-50 ℃, filtering, concentrating and drying to obtain the peel extract.

4. The method for preparing an antibacterial sanitary napkin for preventing side leakage according to claim 1, wherein the method for preparing the pulp extract comprises the following steps: squeezing 6-10 parts of banana pulp and 5-8 parts of kiwi fruit pulp into juice, heating the juice to 80-90 ℃ within 3-5 min, adding pectinase which is 0.05-0.12 times of the weight of the juice, carrying out constant-temperature enzymolysis for 20-30 min, carrying out enzymolysis with pH of 3.5-4.5 and temperature of 48-52 ℃, filtering with filter cloth with the aperture of 0.01-0.1 mm, centrifuging the filtrate, collecting supernatant, and concentrating the supernatant into paste under the conditions of temperature of 46-58 ℃ and vacuum degree of 0.02-0.03 MPa to obtain the pulp extract.

5. The method for preparing an antibacterial sanitary towel for preventing the side leakage according to claim 1, wherein the method for preparing the Chinese herbal medicine extract comprises the following steps: decocting 3-7 parts of evening primrose and 5-10 parts of motherwort in deionized water 6-8 times of the weight of the whole plant, filtering, and spray drying to obtain the Chinese herbal medicine extract.

6. The method for preparing the anti-side leakage antibacterial sanitary towel according to claim 4, wherein the pectinase is selected from food grade, and the enzyme activity is 15000U/g.

7. The method for preparing an antibacterial side-leakage-preventing sanitary napkin as claimed in claim 4, wherein the density of the pasty pulp extract is 3.15-5.2 g/cm³。

8. The preparation method of the side-leakage-preventing antibacterial sanitary towel as claimed in claim 5, wherein the air inlet temperature of spray drying is 120-140 ℃, the air outlet temperature is 100-110 ℃, and the feeding speed is 2-3 ml/min.

9. The method for preparing the lateral leakage preventing antibacterial sanitary towel according to claim 1, wherein the thickness of the skin-friendly layer is 1-2 mm, the thickness of the care layer is 1.2-2 mm, the thickness of the flow guide layer is 1-2 mm, the thickness of the cotton core layer is 3-6 mm, and the thickness of the support layer is 0.4-0.6 mm.

10. The anti-side leakage antibacterial sanitary towel prepared by the preparation method of any one of claims 1 to 9.

Technical Field

The invention belongs to the technical field of sanitary products, and particularly relates to an anti-side-leakage antibacterial sanitary towel and a preparation method thereof.

Background

Along with social progress, the sanitary towel is used as a daily necessity of women, and sanitary towel products with different specifications and types and special performance are invented aiming at preventing and treating various menstrual symptoms. The special medicinal sanitary towel is characterized in that natural Chinese herbal medicines are picked according to the physiological and pathological characteristics of the female menstrual period, and the special medicinal sanitary towel can play the curative effects of resisting bacteria, diminishing inflammation, warming the channels and relieving pain through scientific preparation; the Chinese and western medicines with the effects of killing and inhibiting pathogenic microorganisms, diminishing inflammation and relieving pain are formulated, so that the discomfort symptoms of pruritus vulvae, burning pain, much secretion, stinking smell and the like caused by female menstrual infection can be obviously optimized. However, the following aspects to be further optimized exist:

(1) the side leakage of the sanitary towel is easy to occur, which leads to the embarrassment of women in menstrual period.

(2) The preparation method of the conventional medicinal sanitary towel is that after materials are selected, the medicines and other components are ground into fine powder and uniformly spread on a cotton board of the sanitary towel, which may have adverse stimulation and toxic and side effects; the sanitary towel with the antibacterial function is added with the bactericidal chemical liquid, so that the problems of poor stability, precipitation and the like exist, and the existing antibacterial sanitary towel has a better antibacterial effect on escherichia coli but has a poor antibacterial effect on staphylococcus aureus.

(3) Has short shelf life and is easy to agglomerate to influence the using effect.

Disclosure of Invention

The invention aims to overcome the defects of the prior art and provide the side-leakage-preventing antibacterial sanitary towel which has long shelf life and antibacterial and disinfection effects.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows:

a preparation method of an anti-side-leakage antibacterial sanitary towel comprises a skin-friendly layer, a flow guide layer, a cotton core layer and a support layer which are sequentially compounded from top to bottom, wherein protective wings for preventing side leakage are arranged on two sides of the support layer;

a nursing layer is arranged between the skin-friendly layer and the diversion layer, and is formed by soaking non-woven fabrics in sanitary towel fluff pulp uniformly adsorbed with mixed medicament, taking out and drying;

the mixed medicament is prepared by mixing the following raw materials in parts by weight: 6-10 parts of tea extract, 10-14 parts of peel extract, 3-5 parts of pulp extract and 6-12 parts of Chinese herbal medicine extract.

Preferably, the preparation method of the tea extract comprises the following steps: crushing 8-15 parts of Java tea, 5-12 parts of Pu' er tea and 3-5 parts of Saina leaves to 30-70 meshes, adding deionized water in an amount which is 4-6 times the weight of the tea, performing microwave pretreatment for 10-20 min, performing water bath extraction for 30-45 min, filtering, combining the filtrates after two times of extraction, cooling to 50-60 ℃, concentrating, and performing vacuum freeze drying for 24-48 h to obtain the tea extract.

Preferably, the preparation method of the pericarp extract comprises the following steps: purifying, extracting and drying 3-5 parts of pomegranate peel and 15-25 parts of gamboge peel, then crushing to 80-100 meshes, adding deionized water in an amount which is 6-8 times the weight of pomegranate peel, carrying out countercurrent extraction for 30-60 min at an ultrasonic frequency of 50-100 KHz and a temperature of 30-50 ℃, filtering, concentrating and drying to obtain the peel extract.

Preferably, the preparation method of the pulp extract comprises the following steps: squeezing 6-10 parts of banana pulp and 5-8 parts of kiwi fruit pulp into juice, heating the juice to 80-90 ℃ within 3-5 min, adding pectinase which is 0.05-0.12 times of the weight of the juice, carrying out constant-temperature enzymolysis for 20-30 min, carrying out enzymolysis with pH of 3.5-4.5 and temperature of 48-52 ℃, filtering with filter cloth with the aperture of 0.01-0.1 mm, centrifuging the filtrate, collecting supernatant, and concentrating the supernatant into paste under the conditions of temperature of 46-58 ℃ and vacuum degree of 0.02-0.03 MPa to obtain the pulp extract.

Preferably, the preparation method of the Chinese herbal medicine extract comprises the following steps: decocting 3-7 parts of evening primrose and 5-10 parts of motherwort in deionized water 6-8 times of the weight of the whole plant, filtering, and spray drying to obtain the Chinese herbal medicine extract.

Preferably, the pectinase is selected from food grade, and the enzyme activity is 15000U/g.

Preferably, the density of the pasty pulp extract is 3.15-5.2 g/cm³。

Preferably, the air inlet temperature of the spray drying is 120-140 ℃, the air outlet temperature is 100-110 ℃, and the feeding speed is 2-3 ml/min.

Preferably, the thickness of the skin-friendly layer is 1-2 mm, the thickness of the nursing layer is 1.2-2 mm, the thickness of the flow guide layer is 1-2 mm, the thickness of the cotton core layer is 3-6 mm, and the thickness of the support layer is 0.4-0.6 mm.

Based on one general inventive concept, another object of the present invention is to protect the side-leakage prevention antibacterial sanitary napkin prepared by the above method.

The java tea has obvious curative effect on edema, also has strong antibacterial and anti-inflammatory effects, promotes the elimination of toxic metabolites and has protective effect on the peroxidation injury of biological membranes; the bioactive components contained in the Pu' er tea have the effects of reducing blood fat, losing weight, inhibiting bacteria, aiding digestion, warming stomach, promoting the production of body fluid, quenching thirst, relaxing bowels and the like, are beneficial to losing weight, restoring normal functions of intestines and stomach and solving the problems of acne and the like caused by constipation; the senna leaf has mild characteristics, has the effects of clearing away toxic materials and relaxing the bowels, and is widely applied all over the world; the pomegranate peel contains total flavonoids, alkaloids and the like, and has strong oxidation resistance, good antibacterial effect and anticancer property; the main effective component of the gamboge pericarp is HCA (Hydroxy Citric acid; hydroxycitric acid) which is used as a pH value regulator, thus avoiding the side effect on human body caused by the adoption of chemical extracting agents such as Citric acid and the like; the main functions of the hydroxycitric acid are to obstruct the synthesis of fat and stimulate the satiety center, so that the human body does not have a fasting feeling easily, and the hydroxycitric acid can promote the combustion of fatty acid and reduce the intake of food by inhibiting the synthesis of fat, so as to achieve the effects of slimming and losing weight by combining the following three functions: when human glucose is converted into fat, one of ATP Citrate lyase enzymes is inhibited, fatty acid cannot be synthesized, and Glycolysis (Glycolysis) is inhibited; evening primrose oil has effects of promoting fat metabolism, moistening skin, reducing weight, and regulating insomnia, amnesia, pachylosis, mottle, facial wrinkle, and sallow complexion caused by female estrogen level; herba Leonuri has effects of promoting blood circulation, regulating menstruation, inducing diuresis, and relieving swelling, and can be used for treating menoxenia, dysmenorrhea, amenorrhea, and acute nephritis edema; bananas and kiwi fruits contain rich vitaminsVitamin B, including vitamin B₁Vitamin B₂Vitamin B₆Vitamin B₁₂The vitamin B group acts on the nervous system of the human body to promote the body to generate energy, can relieve and inhibit anxiety and nervous tension, contains abundant cellulose and is beneficial to gastrointestinal peristalsis.

Compared with the prior art, the invention can effectively prolong the shelf life of the sanitary towel, and the prepared sanitary towel has the effects of sterilization and disinfection. The pharmacological functions of the traditional Chinese medicine composition have the functions of clearing heat, drying dampness, removing dirt with aromatics, detoxifying, killing insects, dispelling wind, relieving itching, inhibiting bacteria in a broad spectrum, diminishing inflammation, relieving pain and the like. The raw materials of the medicine are sterilized by ultraviolet rays, the functional substances are uniformly adsorbed in the fluff pulp, and the shelf life of the prepared medicinal sanitary towel is five years. Compared with the prior similar sanitary napkins, the medicinal sanitary napkin of the invention not only keeps the advantages of the similar sanitary napkins of no drug resistance, natural application and the like, but also has excellent curative effect on dysmenorrhea with effective rate of about 90 percent through clinical verification due to reasonable administration, and can improve the general symptoms of patients. In addition, the invention unexpectedly achieves remarkable synergistic effect in relaxing bowels and slimming, and has the effects of beautifying and nursing particularly suitable for women. The sanitary towel prepared by the method of the invention has the advantages of unchanged original performance and processing technology, and practical production significance and value.

Detailed Description

The present invention will be further described with reference to specific embodiments for making the objects, technical solutions and advantages of the present invention more apparent, but the present invention is not limited to these examples. It should be noted that, without conflict, any combination between the embodiments or technical features described below may form a new embodiment. In the invention, all parts and percentages are mass units, and the adopted equipment, raw materials and the like can be purchased from the market or are commonly used in the field. The methods in the following examples are conventional in the art unless otherwise specified.

Example 1

An anti-side-leakage antibacterial sanitary towel comprises a skin-friendly layer, a flow guide layer, a cotton core layer and a support layer which are sequentially compounded from top to bottom, wherein protective wings for preventing side leakage are arranged on two sides of the support layer;

a nursing layer is arranged between the skin-friendly layer and the diversion layer, and is formed by soaking non-woven fabrics in sanitary towel fluff pulp uniformly adsorbed with mixed medicament, taking out and drying;

the mixed medicament is prepared by mixing the following raw materials in parts by weight: 8 parts of tea extract, 12 parts of pericarp extract, 4 parts of pulp extract and 9 parts of Chinese herbal medicine extract.

The preparation method of the tea extract comprises the following steps: pulverizing 12 parts of Java tea, 8 parts of Pu' er tea and 4 parts of Saina leaf into 50 meshes, adding 5 times of deionized water, performing microwave pretreatment for 15min, leaching in water bath for 36min, filtering, combining filtrates after leaching twice, cooling to 55 ℃, concentrating, and performing vacuum freeze drying for 36h to obtain the tea extract.

The preparation method of the pericarp extract comprises the following steps: purifying, extracting and drying 4 parts of pomegranate peel and 20 parts of gamboge peel, then crushing to 90 meshes, adding deionized water with the weight being 7 times that of the pomegranate peel, carrying out countercurrent extraction for 45min at the ultrasonic frequency of 75KHz and the temperature of 40 ℃, filtering, concentrating and drying to obtain the peel extract.

The preparation method of the pulp extract comprises the following steps: squeezing 8 parts of banana pulp and 6.5 parts of kiwi fruit pulp into juice, heating the juice to 85 ℃ within 4min, adding food-grade pectase (enzyme activity 15000U/g) which is 0.08 times of the weight of the juice, carrying out enzymolysis at constant temperature for 25min, carrying out enzymolysis at pH 4.0 and temperature 50 ℃, filtering with filter cloth with pore diameter of 0.05mm, centrifuging the filtrate, collecting supernatant, and concentrating the supernatant to density 4.08g/cm under the conditions of temperature 52 ℃ and vacuum degree of 0.025MPa³And (4) obtaining a pulp extract.

The preparation method of the Chinese herbal medicine extract comprises the following steps: decocting 5 parts of evening primrose and 7.5 parts of motherwort in deionized water in an amount which is 7 times of the weight of the whole plant, filtering, and spray-drying to obtain a Chinese herbal medicine extract;

wherein the air inlet temperature of the spray drying is 130 ℃, the air outlet temperature is 105 ℃, and the feeding speed is 2.5 ml/min.

The thickness of the skin-friendly layer is 1.5mm, the thickness of the care layer is 1.6mm, the thickness of the flow guide layer is 1.5mm, the thickness of the cotton core layer is 4.5mm, and the thickness of the support layer is 0.5 mm.

Example 2

An anti-side-leakage antibacterial sanitary towel comprises a skin-friendly layer, a flow guide layer, a cotton core layer and a support layer which are sequentially compounded from top to bottom, wherein protective wings for preventing side leakage are arranged on two sides of the support layer;

a nursing layer is arranged between the skin-friendly layer and the diversion layer, and is formed by soaking non-woven fabrics in sanitary towel fluff pulp uniformly adsorbed with mixed medicament, taking out and drying;

the mixed medicament is prepared by mixing the following raw materials in parts by weight: 10 parts of tea extract, 10 parts of pericarp extract, 5 parts of pulp extract and 6 parts of Chinese herbal medicine extract.

The preparation method of the tea extract comprises the following steps: crushing 15 parts of java tea, 5 parts of puer tea and 5 parts of senna leaf into 30 meshes, adding deionized water with the weight of 6 times, carrying out microwave pretreatment for 10min, carrying out water bath extraction for 45min, filtering, combining the filtrates after two extractions, cooling to 50 ℃, concentrating, and carrying out vacuum freeze drying for 48h to obtain the tea extract.

The preparation method of the pericarp extract comprises the following steps: purifying, extracting and drying 5 parts of pomegranate peel and 15 parts of gamboge peel, then crushing to 100 meshes, adding deionized water with 6 times of weight, carrying out countercurrent extraction for 60min at the ultrasonic frequency of 100KHz and the temperature of 30 ℃, filtering, concentrating and drying to obtain the peel extract.

The preparation method of the pulp extract comprises the following steps: squeezing 10 parts of banana meat and 5 parts of kiwi fruit meat to obtain juice, heating the juice to 80 deg.C within 5min, adding food grade pectase (enzyme activity 15000U/g) 0.12 times of the juice weight, performing enzymolysis at constant temperature for 20min, performing enzymolysis at pH 4.5 and temperature 48 deg.C, filtering with filter cloth with pore diameter of 0.1mm, centrifuging the filtrate, collecting supernatant, and collecting the supernatantConcentrating at 46 deg.C under vacuum degree of 0.02MPa to density of 5.12g/cm³And (4) obtaining a pulp extract.

The preparation method of the Chinese herbal medicine extract comprises the following steps: decocting 7 parts of evening primrose and 5 parts of motherwort with deionized water in an amount which is 8 times the weight of the whole plant, filtering, and spray-drying to obtain a Chinese herbal medicine extract;

wherein the air inlet temperature of the spray drying is 140 ℃, the air outlet temperature is 100 ℃, and the feeding speed is 3 ml/min.

The thickness of the skin-friendly layer is 2mm, the thickness of the nursing layer is 1.2mm, the thickness of the flow guide layer is 2mm, the thickness of the cotton core layer is 3mm, and the thickness of the support layer is 0.6 mm.

Example 3

An anti-side-leakage antibacterial sanitary towel comprises a skin-friendly layer, a flow guide layer, a cotton core layer and a support layer which are sequentially compounded from top to bottom, wherein protective wings for preventing side leakage are arranged on two sides of the support layer;

a nursing layer is arranged between the skin-friendly layer and the diversion layer, and is formed by soaking non-woven fabrics in sanitary towel fluff pulp uniformly adsorbed with mixed medicament, taking out and drying;

the mixed medicament is prepared by mixing the following raw materials in parts by weight: 6 parts of tea extract, 14 parts of pericarp extract, 3 parts of pulp extract and 12 parts of Chinese herbal medicine extract.

The preparation method of the tea extract comprises the following steps: crushing 8 parts of java tea, 12 parts of puer tea and 3 parts of senna leaves to 70 meshes, adding deionized water with the weight of 4 times of the weight of the java tea, pretreating by microwave for 20min, leaching in water bath for 30min, filtering, combining the filtrates after leaching twice, cooling to 60 ℃, concentrating, and carrying out vacuum freeze drying for 24h to obtain the tea extract.

The preparation method of the pericarp extract comprises the following steps: purifying, extracting and drying 3 parts of pomegranate peel and 25 parts of gamboge peel, then crushing to 80 meshes, adding 8 times of deionized water by weight, carrying out countercurrent extraction for 30min at an ultrasonic frequency of 50KHz and a temperature of 50 ℃, filtering, concentrating and drying to obtain a peel extract.

The preparation method of the pulp extract comprises the following steps: mixing 6 parts of banana pulpSqueezing fructus Actinidiae chinensis with 8 parts of pulp to obtain juice, heating the juice to 90 deg.C within 3min, adding food grade pectase (enzyme activity 15000U/g) 0.05 times of the weight of the juice, performing enzymolysis at constant temperature for 30min, pH 3.5 and temperature 52 deg.C, filtering with filter cloth with pore diameter 0.01mm, centrifuging the filtrate, collecting supernatant, concentrating the supernatant at 58 deg.C and vacuum degree 0.02MPa to density 3.15g/cm³And (4) obtaining a pulp extract.

The preparation method of the Chinese herbal medicine extract comprises the following steps: decocting 3 parts of evening primrose and 10 parts of motherwort with deionized water 6 times of the total weight of the plants, filtering, and spray drying to obtain a Chinese herbal medicine extract;

wherein the air inlet temperature of the spray drying is 120 ℃, the air outlet temperature is 110 ℃, and the feeding speed is 2 ml/min.

The thickness of the skin-friendly layer is 1mm, the thickness of the nursing layer is 2mm, the thickness of the flow guide layer is 1mm, the thickness of the cotton core layer is 6mm, and the thickness of the support layer is 0.4 mm.

Comparative example 1

The utility model provides a sanitary towel, includes from the top down complex parent's skin top layer, water conservancy diversion layer, absorbed layer and bottom in proper order, and the both sides of bottom still are provided with the flap that is used for preventing the edge leakage, still be provided with the nursing layer between parent's skin top layer and the water conservancy diversion layer, the nursing layer is soaked by the non-woven fabrics and is taken out the drying after the nursing liquid and form.

The soaking time is 7 hours, the drying temperature is 200 ℃, and the drying time is 130 minutes.

The care solution is prepared from the following raw materials in parts by weight:

polysorbate 1, sodium carboxymethylcellulose 2, graphene powder 4, tetrabutyl titanate 40, a traditional Chinese medicine composition 30, triethanolamine 8, stearic acid 7, dimethyl carbonate 20 and a catalyst 0.1.

The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight:

11 parts of baked ginger, 4 parts of cassia twig, 9 parts of clove, 40 parts of honeysuckle, 3 parts of oriental wormwood, 2 parts of common cnidium fruit, 14 parts of dandelion, 15 parts of coptis chinensis, 3 parts of motherwort, 11 parts of glabrous greenbrier rhizome and 30 parts of lightyellow sophora root.

The catalyst is p-toluenesulfonic acid.

The preparation method of the care solution comprises the following steps:

(1) heating stearic acid for softening, mixing with graphene powder, stirring uniformly, adding triethanolamine, feeding into a reaction kettle, introducing nitrogen, adding a catalyst, adjusting the temperature of the reaction kettle to 180 ℃, keeping the temperature and stirring for 40 hours, discharging and cooling to obtain esteramine modified graphene;

(2) adding polysorbate into dimethyl carbonate, and stirring to obtain ester dispersion liquid;

(3) adding the ester amine modified graphene into an ester dispersion liquid, uniformly stirring, keeping the temperature at 60 ℃ and stirring for 40 hours, discharging, and removing dimethyl carbonate by rotary evaporation to obtain water-dispersed modified graphene;

(4) grinding the traditional Chinese medicine composition into powder, mixing the powder with the water-dispersible modified graphene and the sodium carboxymethyl cellulose, uniformly stirring, adding the mixture into deionized water 50 times the weight of the mixture, raising the temperature to 95 ℃, keeping the temperature, stirring for 20 minutes, cooling to normal temperature, and adding tetrabutyl titanate to obtain the antibacterial solution.

Comparative example 2

An anti-side-leakage antibacterial sanitary towel comprises a skin-friendly layer, a flow guide layer, a cotton core layer and a support layer which are sequentially compounded from top to bottom, wherein protective wings for preventing side leakage are arranged on two sides of the support layer;

a nursing layer is arranged between the skin-friendly layer and the diversion layer, and is formed by soaking non-woven fabrics in sanitary towel fluff pulp uniformly adsorbed with Chinese herbal medicine extracts, taking out and drying;

the preparation method of the Chinese herbal medicine extract comprises the following steps: decocting 5 parts of evening primrose and 7.5 parts of motherwort in deionized water in an amount which is 7 times of the weight of the whole plant, filtering, and spray-drying to obtain a Chinese herbal medicine extract;

wherein the air inlet temperature of the spray drying is 130 ℃, the air outlet temperature is 105 ℃, and the feeding speed is 2.5 ml/min.

The thickness of the skin-friendly layer is 1.5mm, the thickness of the care layer is 1.6mm, the thickness of the flow guide layer is 1.5mm, the thickness of the cotton core layer is 4.5mm, and the thickness of the support layer is 0.5 mm.

Comparative example 3

An anti-side-leakage antibacterial sanitary towel comprises a skin-friendly layer, a flow guide layer, a cotton core layer and a support layer which are sequentially compounded from top to bottom, wherein protective wings for preventing side leakage are arranged on two sides of the support layer;

a nursing layer is arranged between the skin-friendly layer and the diversion layer, and is formed by soaking non-woven fabrics in sanitary towel fluff pulp uniformly adsorbed with mixed medicament, taking out and drying;

the mixed medicament is prepared by mixing the following raw materials in parts by weight: 8 parts of tea extract and 9 parts of Chinese herbal medicine extract.

The preparation method of the tea extract comprises the following steps: pulverizing 12 parts of Java tea, 8 parts of Pu' er tea and 4 parts of Saina leaf into 50 meshes, adding 5 times of deionized water, performing microwave pretreatment for 15min, leaching in water bath for 36min, filtering, combining filtrates after leaching twice, cooling to 55 ℃, concentrating, and performing vacuum freeze drying for 36h to obtain the tea extract.

The preparation method of the Chinese herbal medicine extract comprises the following steps: decocting 5 parts of evening primrose and 7.5 parts of motherwort in deionized water in an amount which is 7 times of the weight of the whole plant, filtering, and spray-drying to obtain a Chinese herbal medicine extract;

wherein the air inlet temperature of the spray drying is 130 ℃, the air outlet temperature is 105 ℃, and the feeding speed is 2.5 ml/min.

The thickness of the skin-friendly layer is 1.5mm, the thickness of the care layer is 1.6mm, the thickness of the flow guide layer is 1.5mm, the thickness of the cotton core layer is 4.5mm, and the thickness of the support layer is 0.5 mm.

Comparative example 4

An anti-side-leakage antibacterial sanitary towel comprises a skin-friendly layer, a flow guide layer, a cotton core layer and a support layer which are sequentially compounded from top to bottom, wherein protective wings for preventing side leakage are arranged on two sides of the support layer;

a nursing layer is arranged between the skin-friendly layer and the diversion layer, and is formed by soaking non-woven fabrics in sanitary towel fluff pulp uniformly adsorbed with mixed medicament, taking out and drying;

the mixed medicament is prepared by mixing the following raw materials in parts by weight: 8 parts of tea extract, 12 parts of pericarp extract and 9 parts of Chinese herbal medicine extract.

The preparation method of the tea extract comprises the following steps: pulverizing 12 parts of Java tea, 8 parts of Pu' er tea and 4 parts of Saina leaf into 50 meshes, adding 5 times of deionized water, performing microwave pretreatment for 15min, leaching in water bath for 36min, filtering, combining filtrates after leaching twice, cooling to 55 ℃, concentrating, and performing vacuum freeze drying for 36h to obtain the tea extract.

The preparation method of the pericarp extract comprises the following steps: purifying, extracting and drying 4 parts of pomegranate peel and 20 parts of gamboge peel, then crushing to 90 meshes, adding deionized water with the weight being 7 times that of the pomegranate peel, carrying out countercurrent extraction for 45min at the ultrasonic frequency of 75KHz and the temperature of 40 ℃, filtering, concentrating and drying to obtain the peel extract.

The preparation method of the Chinese herbal medicine extract comprises the following steps: decocting 5 parts of evening primrose and 7.5 parts of motherwort in deionized water in an amount which is 7 times of the weight of the whole plant, filtering, and spray-drying to obtain a Chinese herbal medicine extract;

wherein the air inlet temperature of the spray drying is 130 ℃, the air outlet temperature is 105 ℃, and the feeding speed is 2.5 ml/min.

The thickness of the skin-friendly layer is 1.5mm, the thickness of the care layer is 1.6mm, the thickness of the flow guide layer is 1.5mm, the thickness of the cotton core layer is 4.5mm, and the thickness of the support layer is 0.5 mm.

Toxicological test

1. Acute toxicity test

The medicine comprises the following components: the mixed medicament is decocted into decoction according to the invention, and then the decoction is placed in a refrigerator for storage and standby.

② testing animals: the weight of the white mouse is 30-50 g, and male and female mice are randomly selected.

③ method and results: taking 50 mice, dividing into 5 groups, feeding 10 mice each group after starvation for about 15 hours, feeding 20ml of medicine for each group, respectively feeding the medicines for 1, 2, 3, 4 and 5 groups within 24 hours for 1, 2, 3, 4 and 5 times, observing for 5 days, wherein the mice have normal activity, no toxic reaction and no death. Wherein, the dosage of the mice is calculated according to the dosage of kilogram body weight, which shows that the decoction has no acute toxicity and the clinical dosage is safe.

2. Long term toxicity test

The medicine comprises the following components: the mixed medicament is decocted into decoction according to the invention, and then the decoction is placed in a refrigerator for storage and standby.

② testing animals: the weight of the white rat is 120-130 g, and male white rats are selected.

③ method and results: taking 50 rats, dividing the rats into 5 groups, and dividing each group into 10 rats, wherein the 1 st, 2 nd, 3 th and 4 th groups are used as administration groups, each group is respectively filled with 20ml, 30ml, 40ml and 50ml of medicine, the fifth group is normally fed as a control group, the administration groups are continuously filled once a day for 90 days, the body weight is measured, the rats are killed after being decapitated 24 hours after the last administration, the routine blood, urine, liver function and kidney function are measured, the viscera such as heart and kidney are taken, the change of tissue morphology is observed, the effect of dosage is observed, the change of diet and activity is observed, the experiment proves that the administration groups and the control groups have no obvious change, and the dosage which is 50-200 times of clinical application according to kilogram body weight has no toxic reaction.

Performance testing

1. And (3) antibacterial property: with reference to appendix C4 of GB 15979-2012 'hygienic Standard for Disposable sanitary articles', the bacteriostatic rates of the sanitary napkins of examples 1-3 and comparative examples 1-4 after being inoculated with Escherichia coli and Staphylococcus aureus for 4h, 8h and 12h respectively were measured, wherein the bacteriostatic rate is greater than 99% and is recorded as A, the bacteriostatic rate is 95-99% and is recorded as B, the bacteriostatic rate is 85-95% and is not equal to 95% and is recorded as C, the bacteriostatic rate is 65-85% and is not equal to 85% and is recorded as D, the bacteriostatic rate is less than 65% and is recorded as E, and the test results are shown in Table 1 below.

2. And (3) stability of the antibacterial liquid: the mixed medicaments in the examples 1 to 3 are dissolved in ethanol and uniformly mixed to prepare the antibacterial solution, the care solution in the comparative example 1, the Chinese herbal medicine extract in the comparative example 2 are dissolved in ethanol and uniformly mixed to prepare the antibacterial solution, and the mixed medicaments in the comparative examples 3 to 4 are dissolved in ethanol and uniformly mixed to prepare the antibacterial solution, and the prepared antibacterial solution is respectively placed still at 25 ℃ for 6 months to observe whether the precipitation phenomenon occurs or not, wherein the test results are shown in the following table 1.

TABLE 1 Performance test results of sanitary napkins described in examples 1-3 and comparative examples 1-4

As can be seen from the comparison between examples 1 to 3 of Table 1 and comparative example 1, the sanitary napkin prepared by the method of the present invention has a stable antibacterial property, compared to the prior art, the antibacterial property of the herbal extract of the present invention is superior to that of the care solution of comparative example 1, compared to comparative example 2, the antibacterial property of the herbal extract of the present invention is further enhanced by the tea extract, compared to comparative example 3, the antibacterial property of the mixture of the herbal extract of the present invention and the tea extract is further enhanced by the fruit peel extract, compared to comparative example 3 and comparative example 4, the antibacterial property of the mixture of the herbal extract of the present invention and the tea extract is further enhanced by the fruit pulp extract, the antibacterial property of the mixture of tea extract and pericarp extract.

3. Shelf life: the sanitary napkins of the embodiments 1 to 3 and the comparative examples 1 to 4 are tested by a conventional method for detecting the shelf life of the sanitary napkins in the field, and the results show that the average shelf life of the sanitary napkins prepared in the embodiments 1 to 3 is about five years, the shelf life of the sanitary napkin in the comparative example 1 is three years, the shelf life of the sanitary napkin in the comparative example 2 is about four years, and the shelf life of the sanitary napkins in the comparative examples 3 to 4 is about five years, which indicates that the addition of the peel extract in the invention is helpful for remarkably improving the shelf life of the sanitary napkins. In addition, the SGS fluorescent agent-free test shows that the sanitary napkins in the embodiments 1-3 of the invention are all free of fluorescent whitening agents.

4. Comfort: the sanitary napkins of example 1 and comparative examples 1 to 4 were distributed to women aged 16 to 42, and divided into seven groups, each group of women having the same average age, and after fifteen menstrual cycles, the sanitary napkin was subjected to a questionnaire survey about the problems of the antibacterial property and the side leakage or not, and after the participants of the questionnaire survey tried the sanitary napkin of the present invention, the results of the evaluation about the antibacterial property and the side leakage or not, wherein 98% of questionnaire participants judge that the sanitary napkins of example 1 of the present invention are superior to those of comparative examples 1-4 in antibacterial and side leakage prevention aspects, the effects of the raw napkins of comparative examples 3-4 in terms of antibiosis and side leakage are significantly better than those of the sanitary napkins of comparative examples 1-2, and presumably due to the fact that the main effective component of the gamboge pericarp is HCA (Hydroxy Citric acid; hydroxycitric acid) which is used as a pH value regulator, side effects of chemical extraction agents such as Citric acid on human bodies are avoided. In addition, the questionnaire participants felt themselves that after use of example 1, the morbid lightness of the body, the symptoms of dysmenorrhea improved, and the users with constipation indicated the disappearance of the symptoms, presumably because java tea in the tea extract had a significant therapeutic effect on edema, promoted the elimination of toxic metabolites, and had a protective effect on the peroxidative damage of biological membranes; the bioactive components in the Pu' er tea have various effects of reducing blood fat, inhibiting bacteria, promoting digestion, relaxing bowels and the like, and solve the problems of acne and the like caused by constipation; the Saina leaf has mild property, and has effects of clearing away toxic materials and relieving constipation.

The above embodiments are merely preferred embodiments of the present invention, and any simple modification, modification and substitution changes made to the above embodiments according to the technical spirit of the present invention are within the scope of the technical solution of the present invention.