阅读说明：本技术 一种抗皱化妆品及其制备方法 (Anti-wrinkle cosmetic and preparation method thereof ) 是由 张庆 孔令超 于 2021-08-12 设计创作，主要内容包括：本发明涉及化妆品技术领域,具体涉及一种抗皱化妆品及其制备方法。所述抗皱化妆品中含有枫叶提取物、小球藻提取物、欧蓍草提取物、假交替单胞菌发酵产物提取物、生育酚乙酸酯、寡肽-1、寡肽-2、寡肽-5等多种活性成分,具有多重美容护肤作用,对肌肤皱纹具有协同增效的抗皱效果,能够促进皮肤细胞新陈代谢,有效对抗不同类型的肌肤衰老、减轻皱纹,使肌肤白皙水嫩、富有弹性和光泽。本发明的抗皱化妆品性质温和无刺激,长期使用安全性高且无副作用。此外,本发明的抗皱化妆品制备方法简单便捷,利于大规模的生产应用。(The invention relates to the technical field of cosmetics, in particular to an anti-wrinkle cosmetic and a preparation method thereof. The anti-wrinkle cosmetic contains various active ingredients such as maple leaf extract, chlorella extract, yarrow extract, pseudoalteromonas fermentation product extract, tocopherol acetate, oligopeptide-1, oligopeptide-2, oligopeptide-5 and the like, has multiple skin-beautifying and skin-protecting effects, has a synergistic anti-wrinkle effect on skin wrinkles, can promote skin cell metabolism, effectively resist different types of skin aging, alleviate wrinkles and make the skin white, tender, elastic and glossy. The anti-wrinkle cosmetic disclosed by the invention is mild in property, free of stimulation, high in safety after long-term use and free of side effects. In addition, the preparation method of the anti-wrinkle cosmetic is simple and convenient, and is beneficial to large-scale production and application.)

1. The anti-wrinkle cosmetic composition is characterized by comprising the following raw material components in parts by weight: 8-12 parts of maple leaf extract, 6-10 parts of chlorella extract, 6-10 parts of yarrow extract, 4-8 parts of pseudoalteromonas fermentation product extract, 3-7 parts of tocopherol acetate, 11-3 parts of oligopeptide-11, 21-3 parts of oligopeptide-21 and 51-3 parts of oligopeptide-51.

2. The anti-wrinkle cosmetic composition according to claim 1, comprising the following raw material components in parts by weight: 9-11 parts of maple leaf extract, 7-9 parts of chlorella extract, 7-9 parts of yarrow extract, 5-7 parts of pseudoalteromonas fermentation product extract, 4-6 parts of tocopherol acetate, 11.5-2.5 parts of oligopeptide-21.5-2.5 parts of oligopeptide-51.5-2.5 parts of oligopeptide.

3. The anti-wrinkle cosmetic composition according to claim 2, comprising the following raw material components in parts by weight: 10 parts of maple leaf extract, 8 parts of chlorella extract, 8 parts of yarrow extract, 6 parts of pseudoalteromonas fermentation product extract, 3 parts of tocopherol acetate, 12 parts of oligopeptide-22 parts of oligopeptide-52 parts of oligopeptide.

4. The anti-wrinkle cosmetic is characterized by comprising the following raw material components in parts by weight: 28-50 parts of the anti-wrinkle cosmetic composition as defined in any one of claims 1-3, 10-20 parts of emulsifier, 5-10 parts of humectant, 5-10 parts of thickener, 0-5 parts of preservative, 0.5-2 parts of chelating agent and 80-120 parts of deionized water.

5. The anti-wrinkle cosmetic according to claim 4, wherein the emulsifier is selected from at least one of hydrogenated lecithin, cetearyl alcohol, sodium laureth sulfate, PEG-40 stearate, steareth-21.

6. The anti-wrinkle cosmetic according to claim 4, wherein the moisturizer is selected from at least one of glycerin, butylene glycol, trehalose, pentylene glycol, and sodium hyaluronate.

7. The anti-wrinkle cosmetic according to claim 4, wherein the thickener is at least one selected from xanthan gum, carrageenan, hydroxyethyl cellulose, and acryloyldimethyl tauride/VP copolymer.

8. The anti-wrinkle cosmetic according to claim 4, wherein the preservative is selected from at least one of phenoxyethanol, ethylhexyl glycerin, and methylparaben.

9. The anti-wrinkle cosmetic according to claim 4, wherein the chelating agent is EDTA-2 Na.

10. The process for the preparation of an anti-wrinkle cosmetic according to any one of claims 4 to 9, comprising the steps of:

(1) weighing the raw material components in parts by weight for later use;

(2) adding a thickening agent into deionized water, and stirring to completely disperse the thickening agent to obtain a material A;

(3) adding a humectant, a preservative and a chelating agent into the material A, heating to 60-65 ℃, and uniformly stirring to obtain a material B;

(4) naturally cooling, adding the emulsifier and the anti-wrinkle cosmetic composition into the material B, homogenizing at 30-35 deg.C and 3000rpm for 5-10 min to completely emulsify, mixing, and discharging to obtain the anti-wrinkle cosmetic.

Technical Field

The invention relates to the technical field of cosmetics, in particular to an anti-wrinkle cosmetic and a preparation method thereof.

Background

The skin is directly affected by the surrounding environment and gradually ages, with symptoms of wrinkles, age spots, darkness, laxity, etc. The most immediate outward manifestation of skin aging is the formation of wrinkles. The wrinkles refer to small fine lines and wrinkles formed by the skin affected by external environment, which form free radicals, the free radicals destroy collagen and active substances in normal cell membrane tissues and oxidize cells. Facial wrinkles are divided into two types, atrophied wrinkles and hypertrophic wrinkles. Atrophic wrinkles refer to wrinkles that appear on thin, chapped and dry skin, such as countless fine wrinkles around the eyes; the hypertrophic wrinkles indicate wrinkles appearing on oily skin, which are not numerous and dense and deep in texture, such as wrinkles on the forehead, around the lips, and in the chin. Considering the reason of wrinkle formation and the characteristic types of the wrinkles, the wrinkle resistance and the aging resistance are realized by comprehensively matching active substances such as muscle contraction relieving and skin collagen supplementing in various aspects. When developing anti-wrinkle cosmetics, the reason of wrinkles appearing on skin needs to be comprehensively considered, and the ideal anti-wrinkle effect can be achieved only by simultaneously acting from multiple ways. At present, most of anti-wrinkle cosmetics on the market are products with simple superposed effect components, and some anti-wrinkle cosmetics even cause allergy phenomena such as acne and the like due to overhigh concentration, so the anti-wrinkle skin care effect and the use safety of the products need to be further improved.

Disclosure of Invention

In order to solve the technical problems, the invention provides an anti-wrinkle cosmetic and a preparation method thereof, the anti-wrinkle cosmetic has a remarkable anti-wrinkle effect, can keep the skin of a human body tender, elastic and glossy through reasonable compatibility of various active ingredients, and has no side effect after long-term use.

In order to achieve the purpose, the invention adopts the technical scheme that:

the anti-wrinkle cosmetic composition comprises the following raw material components in parts by weight: 8-12 parts of maple leaf extract, 6-10 parts of chlorella extract, 6-10 parts of yarrow extract, 4-8 parts of pseudoalteromonas fermentation product extract, 3-7 parts of tocopherol acetate, 11-3 parts of oligopeptide-11, 21-3 parts of oligopeptide-21 and 51-3 parts of oligopeptide-51.

Preferably, the anti-wrinkle cosmetic composition comprises the following raw material components in parts by weight: 9-11 parts of maple leaf extract, 7-9 parts of chlorella extract, 7-9 parts of yarrow extract, 5-7 parts of pseudoalteromonas fermentation product extract, 4-6 parts of tocopherol acetate, 11.5-2.5 parts of oligopeptide-21.5-2.5 parts of oligopeptide-51.5-2.5 parts of oligopeptide.

Preferably, the anti-wrinkle cosmetic composition comprises the following raw material components in parts by weight: 10 parts of maple leaf extract, 8 parts of chlorella extract, 8 parts of yarrow extract, 6 parts of pseudoalteromonas fermentation product extract, 3 parts of tocopherol acetate, 12 parts of oligopeptide-22 parts of oligopeptide-52 parts of oligopeptide.

Further, the invention also provides an anti-wrinkle cosmetic which comprises the following raw material components in parts by weight: 28-50 parts of the anti-wrinkle cosmetic composition, 10-20 parts of an emulsifier, 5-10 parts of a humectant, 5-10 parts of a thickener, 0-5 parts of a preservative, 0.5-2 parts of a chelating agent and 80-120 parts of deionized water.

Preferably, the emulsifier is at least one selected from the group consisting of hydrogenated lecithin, cetearyl alcohol, sodium laureth sulfate, PEG-40 stearate, and steareth-21.

Preferably, the humectant is at least one selected from glycerin, butanediol, trehalose, pentanediol and sodium hyaluronate.

Preferably, the thickener is at least one selected from xanthan gum, carrageenan, hydroxyethyl cellulose and acryloyl dimethyl tauryl/VP copolymer.

Preferably, the preservative is at least one selected from phenoxyethanol, ethylhexyl glycerol and methyl paraben.

Preferably, the chelating agent is EDTA-2 Na.

Further, the invention also provides a preparation method of the anti-wrinkle cosmetic, which comprises the following steps:

(1) weighing the raw material components in parts by weight for later use;

(2) adding a thickening agent into deionized water, and stirring to completely disperse the thickening agent to obtain a material A;

(3) adding a humectant, a preservative and a chelating agent into the material A, heating to 60-65 ℃, and uniformly stirring to obtain a material B;

(4) naturally cooling, adding the emulsifier and the anti-wrinkle cosmetic composition into the material B, homogenizing at 30-35 deg.C and 3000rpm for 5-10 min to completely emulsify, mixing, and discharging to obtain the anti-wrinkle cosmetic.

The maple leaf extract is rich in compounds that prevent wrinkle formation and will tighten human skin like botulium. The maple leaf extract can inhibit elastase activity, thereby preventing wrinkle formation. In addition, maple leaf extract also prevents skin irritation, lightening dark spots such as age spots.

The chlorella extract can help skin to promote collagen leukorrhea and elastin synthesis, and has repairing and anti-aging effects. The collagen of chlorella can help reduce the depth of wrinkles, promote the renewal of skin after free radicals and sunlight irradiation, and can regenerate damaged tissues to restore the loose skin to a young state, thereby playing a role in removing wrinkles.

The extract of Achillea millefolium has strong antibacterial property, and can be used for treating acne by combining its antiinflammatory effect. The Achillea millefolium extract has effects of inhibiting elastase, proliferating epidermal keratinocyte, restoring elasticity of skin fiber tissue, balancing and promoting skin cell metabolism, and can be used in anti-wrinkle cosmetics. The Achillea millefolium extract also has certain whitening effect.

The pseudoalteromonas ferment product extract is an extracellular polymeric substance (ECPS) obtained in marine unicellular genus by biotechnology, and is most suitable for oily and mixed skin. The biological component can reduce excessive oil and sebum, shrink pores, and reduce speckle.

The tocopherol acetate belongs to a derivative of vitamin E, is commonly used as an antioxidant in cosmetics, is an oil-soluble natural substance, is a good nutritional moistening agent for skin, can avoid rancidity oxidation of oil and stabilize the oil when added into a care product. It has excellent effects in moisturizing and maintaining connective tissues, and protecting skin from ultraviolet rays, and it makes skin feel soft and retains moisture.

Oligopeptide-1 is used as skin conditioner in cosmetics. Oligopeptide-1 is prepared by combining wheat and soy protein, and the component can stimulate collagen synthesis. Oligopeptide-1 is composed of 3 amino acids such as glycine, histidine, lysine, etc.

The oligopeptides-2 and-5 mainly play a role in cosmetics and skin care products as antioxidants, and small molecules consisting of 2-6 amino acids can be directly and effectively absorbed and utilized by cells to quickly supplement collagen, so that good conditioning effects such as promotion of metabolism, stimulation of cell regeneration, proliferation and collagen regeneration are achieved.

Compared with the prior art, the invention has the beneficial effects that: the anti-wrinkle cosmetic disclosed by the invention contains a plurality of natural plant extracts which are prepared according to a specific proportion, and meanwhile, the anti-wrinkle cosmetic is matched with a plurality of active ingredients such as pseudoalteromonas fermentation product extracts, tocopherol acetate, oligopeptide-1, oligopeptide-2, oligopeptide-5 and the like, so that the anti-wrinkle cosmetic has multiple skin-care effects, has a synergistic anti-wrinkle effect on skin wrinkles, can promote skin cell metabolism, effectively resist different types of skin aging, alleviate wrinkles and make the skin white, tender, elastic and glossy. The anti-wrinkle cosmetic disclosed by the invention is mild in property, free of stimulation, high in safety after long-term use and free of side effects. In addition, the preparation method of the anti-wrinkle cosmetic is simple and convenient, and is beneficial to large-scale production and application.

Detailed Description

The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention. The materials, reagents and the like used are, unless otherwise specified, commercially available reagents and materials.

Source of raw materials

Maple leaf extract purchased from Shanxi Xintianyuan Biotech limited

Chlorella extract purchased from Baoji Cheng biological development Co., Ltd

Achillea millefolium extract, available from West An Lvkang Biotech Ltd

Example 1

An anti-wrinkle cosmetic comprises the following raw material components in parts by weight: 12 parts of maple leaf extract, 10 parts of chlorella extract, 10 parts of yarrow extract, 8 parts of pseudoalteromonas fermentation product extract, 7 parts of tocopherol acetate, 11 parts of oligopeptide, 21 parts of oligopeptide, 51 parts of oligopeptide, 10 parts of hydrogenated lecithin, 10 parts of cetearyl alcohol, 10 parts of butanediol, 10 parts of hydroxyethyl cellulose, 3 parts of phenoxyethanol, 2 parts of EDTA-2Na and 120 parts of deionized water.

The preparation method of the anti-wrinkle cosmetic comprises the following steps:

(1) weighing the raw material components in parts by weight for later use;

(2) adding hydroxyethyl cellulose into deionized water, and stirring to completely disperse the hydroxyethyl cellulose to obtain a material A;

(3) adding butanediol, phenoxyethanol and EDTA-2Na into the material A, heating to 60 ℃, and uniformly stirring to obtain a material B;

(4) naturally cooling, adding hydrogenated lecithin, cetostearyl alcohol and an anti-wrinkle cosmetic composition (maple leaf extract, chlorella extract, milfoil extract, pseudoalteromonas fermentation product extract, tocopheryl acetate, oligopeptide-1, oligopeptide-2 and oligopeptide-5) into the material B, homogenizing at 35 ℃ and 3000rpm for 5 minutes to completely emulsify the mixture, uniformly mixing, and discharging to obtain the anti-wrinkle cosmetic.

Example 2

An anti-wrinkle cosmetic comprises the following raw material components in parts by weight: 8 parts of maple leaf extract, 6 parts of chlorella extract, 6 parts of yarrow extract, 4 parts of pseudoalteromonas fermentation product extract, 3 parts of tocopherol acetate, 12 parts of oligopeptide-22 parts of oligopeptide-52 parts of oligopeptide, 10 parts of sodium laureth sulfate, 2 parts of glycerol, 3 parts of trehalose, 5 parts of xanthan gum, 5 parts of ethylhexyl glycerol, 0.5 part of EDTA-2Na and 80 parts of deionized water.

The preparation method of the anti-wrinkle cosmetic comprises the following steps:

(1) weighing the raw material components in parts by weight for later use;

(2) adding xanthan gum into deionized water, and stirring to completely disperse the xanthan gum to obtain a material A;

(3) adding glycerol, trehalose, ethylhexyl glycerol and EDTA-2Na into the material A, heating to 65 ℃, and uniformly stirring to obtain a material B;

(4) naturally cooling, adding sodium laureth sulfate and an anti-wrinkle cosmetic composition (maple leaf extract, chlorella extract, yarrow extract, pseudoalteromonas fermentation product extract, tocopherol acetate, oligopeptide-1, oligopeptide-2 and oligopeptide-5) into the material B, homogenizing at 30 ℃ and 3000rpm for 10 minutes to completely emulsify, uniformly mixing, and discharging to obtain the anti-wrinkle cosmetic.

Example 3

An anti-wrinkle cosmetic comprises the following raw material components in parts by weight: 10 parts of maple leaf extract, 8 parts of chlorella extract, 8 parts of yarrow extract, 6 parts of pseudoalteromonas fermentation product extract, 3 parts of tocopherol acetate, 13 parts of oligopeptide-23 parts of oligopeptide-53 parts of oligopeptide, 8 parts of PEG-40 stearate, 217 parts of steareth-217, 8 parts of sodium hyaluronate, 8 parts of acryloyldimethyl taurate/VP copolymer, 2 parts of methylparaben, 1 part of EDTA-2Na and 100 parts of deionized water.

The preparation method of the anti-wrinkle cosmetic comprises the following steps:

(1) weighing the raw material components in parts by weight for later use;

(2) adding acryloyl dimethyl tauric acid amine/VP copolymer into deionized water, and stirring to completely disperse the copolymer to obtain a material A;

(3) adding sodium hyaluronate, methyl paraben and EDTA-2Na into the material A, heating to 62 ℃, and uniformly stirring to obtain a material B;

(4) naturally cooling, adding PEG-40 stearate, steareth-21 and an anti-wrinkle cosmetic composition (maple leaf extract, chlorella extract, yarrow extract, pseudoalteromonas fermentation product extract, tocopherol acetate, oligopeptide-1, oligopeptide-2 and oligopeptide-5) into the material B, homogenizing at 32 ℃ and 3000rpm for 8 minutes to completely emulsify the materials, uniformly mixing, and discharging to obtain the anti-wrinkle cosmetic.

Comparative example 1 (in contrast to example 3, no extract of Achillea millefolium)

An anti-wrinkle cosmetic comprises the following raw material components in parts by weight: 14 parts of maple leaf extract, 12 parts of chlorella extract, 6 parts of pseudoalteromonas fermentation product extract, 3 parts of tocopherol acetate, 13 parts of oligopeptide, 23 parts of oligopeptide, 53 parts of oligopeptide, 8 parts of PEG-40 stearate, 8 parts of steareth-217, 8 parts of sodium hyaluronate, 8 parts of acrylamide-dimethyl taurate/VP copolymer, 2 parts of methylparaben, 1 part of EDTA-2Na and 100 parts of deionized water. An anti-wrinkle cosmetic was prepared according to the preparation method in example 3.

Comparative example 2 (compared to example 3, without Chlorella extract)

An anti-wrinkle cosmetic comprises the following raw material components in parts by weight: 14 parts of maple leaf extract, 12 parts of achillea millefolium extract, 6 parts of pseudoalteromonas fermentation product extract, 3 parts of tocopherol acetate, 13 parts of oligopeptide-13, 23 parts of oligopeptide, 53 parts of oligopeptide-40, 8 parts of PEG-40 stearate, 217 parts of steareth-217, 8 parts of sodium hyaluronate, 8 parts of acrylamide/VP copolymer, 2 parts of methylparaben, 1 part of EDTA-2Na and 100 parts of deionized water. An anti-wrinkle cosmetic was prepared according to the preparation method in example 3.

Comparative example 3 (compared to example 3, without maple leaf extract)

An anti-wrinkle cosmetic comprises the following raw material components in parts by weight: 13 parts of chlorella extract, 13 parts of achillea millefolium extract, 6 parts of pseudoalteromonas fermentation product extract, 3 parts of tocopherol acetate, 13 parts of oligopeptide-23 parts of oligopeptide-53 parts of oligopeptide-40, 8 parts of PEG-40 stearate, 8 parts of steareth-217, 8 parts of sodium hyaluronate, 8 parts of acrylamide/VP copolymer, 2 parts of methylparaben, 1 part of EDTA-2Na and 100 parts of deionized water. An anti-wrinkle cosmetic was prepared according to the preparation method in example 3.

Anti-wrinkle Effect test

60 healthy female subjects (divided into 6 groups of 10 persons) between the ages of 40 and 60 are selected, and have habit of using skin care products at ordinary times, and visible wrinkles or fine lines at the canthus. Female subjects fix half face every day, use the anti-wrinkle cosmetic of the invention once in the morning and evening, and use it for 8 weeks by continuous smearing. Other brands of anti-wrinkle type cosmetics were not used during the test. The test was performed 1 time at 0, 2, 4, 6 and 8 weeks, respectively, before each test, the subjects had to clean their faces with fresh water, dry the face water with a sterile paper towel, rest for at least half an hour in a resting state at a temperature of about 20 ℃ and a relative humidity of about 50%, and the measurements were performed by a professional.

The skin at the position of the tail of the left and right eyes was measured using a skin elasticity tester (Courage + Khazaka, Germany, model: MPA 580). The improvement effect of the anti-wrinkle cosmetic on the elasticity of the skin around the eyes was evaluated by using the values of the skin elasticity parameter R5 (the closer the value is to 1, the better the skin elasticity), and the tightening parameter F4 (the smaller the value, the tighter the skin). The skin at the left and right eye tail portions was measured three times each, and the average value was calculated. The results of the experiment are shown in table 1.

The skin of the left and right eye tails of female subjects was photographed by a facial image analyzer (Courage + Khazaka, germany, model: Visioface), the wrinkle visualization coefficient reduction rate (%) was calculated, and the improvement of the eye wrinkles before and after the use of the anti-wrinkle cosmetic was evaluated. The results of the experiment are shown in table 2.

TABLE 1 skin elasticity measurement results

TABLE 2 improvement of skin wrinkles

As can be seen from the experimental results of tables 1 to 2, after weeks 2, 4, 6 and 8 using the anti-wrinkle cosmetics prepared in examples 1 to 3, the values of the elasticity parameter R5 of the canthus skin showed a gradual rising trend, indicating that the skin elasticity was better and better; the tightening parameter F4 value is in a gradually decreasing trend, which shows that the skin tightness is obviously improved; the reduction rate of the wrinkle visualization coefficient is gradually increased, which shows that wrinkles of the skin at the canthus of the eyes of the subject are obviously reduced, and the skin texture is obviously improved. In contrast, after 2 weeks, 4 weeks, 6 weeks, and 8 weeks using the anti-wrinkle cosmetics prepared in comparative examples 1 to 3, the variation range of the above parameter values was narrow and the variation trend was gentle. The results show that the anti-wrinkle cosmetic provided by the invention contains a plurality of natural plant extracts which are prepared according to a specific proportion, and is matched with a plurality of active ingredients such as pseudoalteromonas fermentation product extract, tocopherol acetate, oligopeptide-1, oligopeptide-2, oligopeptide-5 and the like, so that the anti-wrinkle cosmetic has multiple skin-care effects, has a synergistic anti-wrinkle effect on skin wrinkles, can promote skin cell metabolism, effectively resist different types of skin aging, alleviate wrinkles, and make the skin white, tender, elastic and glossy.

The above description is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, several modifications or equivalents may be made to the technical solution without departing from the principle of the present invention, and these modifications or equivalents should also be regarded as the protection scope of the present invention.