阅读说明：本技术 血小板模拟粒子及其制备方法以及含该模拟粒子的质控物或校准物 (Platelet simulation particle, preparation method thereof and quality control substance or calibrator containing the simulation particle ) 是由 孙思祥 谢键 于 2018-12-25 设计创作，主要内容包括：一种制备血小板模拟粒子的方法,其中使用三氟甲基类化合物对动物红细胞进行修饰处理,以制成能结合荧光染料的血小板模拟粒子。该方法能使血小板模拟粒子与荧光染料分子简单、有效地结合。还涉及另一种制备血小板模拟粒子的方法,其中使用单宁酸和醛类对动物红细胞进行固定处理,以制成血小板模拟粒子。该方法能提高血小板模拟粒子的稳定性。此外还涉及按照该方法制备的血小板模拟粒子及含有该血小板模拟粒子的质控物或校准物。(A method for producing platelet-mimetic particles, wherein animal erythrocytes are subjected to a modification treatment with a trifluoromethyl compound to produce platelet-mimetic particles capable of binding a fluorescent dye. The method can simply and effectively combine the platelet simulation particles with the fluorescent dye molecules. Also relates to another method for preparing platelet-mimetic particles, in which animal erythrocytes are subjected to a fixation treatment using tannic acid and aldehydes to prepare platelet-mimetic particles. The method can improve stability of platelet-simulated particle. Also disclosed are platelet-simulating particles produced by the method, and a quality control material or calibrator containing the platelet-simulating particles.)