阅读说明：本技术 一种用于单细胞转录组测序技术的细胞分离装置 (Cell separation device for single cell transcriptome sequencing technology ) 是由 齐先佳 齐媛 李丽 于 2021-01-15 设计创作，主要内容包括：本发明公开了一种用于单细胞转录组测序技术的细胞分离装置,包括设备外壳,所述设备外壳的顶部外壁上安装有顶盖,且设备外壳的正面壳壁上设有控制面板,所述设备外壳的内部设有横板,且横板与设备外壳的底部内壁之间焊接有多个竖板,两个所述竖板相互远离的一侧焊接有位于设备外壳内部的隔板,所述设备外壳的底部内壁上固定连接有电机,且电机的输出端安装有转轴,所述转轴上通过螺栓连接有主动锥齿轮。本发明通过各种结构的组合使得本装置在使用过程中不需要另外的驱动装置实现对设备内部的风力散热,减少结构,节约成本,且本装置在实现风力散热的同时同步实现对散热板的灰尘清理,防止其粘附大量的灰尘而堵塞,延长设备的使用寿命。(The invention discloses a cell separation device for a unicellular transcriptome sequencing technology, which comprises an equipment shell, wherein a top cover is installed on the outer wall of the top of the equipment shell, a control panel is arranged on the wall of the front shell of the equipment shell, a transverse plate is arranged inside the equipment shell, a plurality of vertical plates are welded between the transverse plate and the inner wall of the bottom of the equipment shell, a partition plate positioned inside the equipment shell is welded on one side, away from each other, of the two vertical plates, a motor is fixedly connected to the inner wall of the bottom of the equipment shell, a rotating shaft is installed at the output end of the motor, and a driving bevel gear is connected to the rotating shaft. According to the invention, through the combination of various structures, the device does not need an additional driving device to realize wind power heat dissipation in the equipment in the use process, the structure is reduced, the cost is saved, the device realizes wind power heat dissipation and synchronously realizes dust cleaning of the heat dissipation plate, the blockage caused by adhesion of a large amount of dust is prevented, and the service life of the equipment is prolonged.)

1. A cell separation device for a unicellular transcriptome sequencing technology comprises an equipment shell (1) and is characterized in that a top cover (2) is installed on the outer wall of the top of the equipment shell (1), a control panel (3) is arranged on the front shell wall of the equipment shell (1), a transverse plate (4) is arranged inside the equipment shell (1), a plurality of vertical plates (5) are welded between the transverse plate (4) and the inner wall of the bottom of the equipment shell (1), a partition plate (6) positioned inside the equipment shell (1) is welded on one side, far away from each other, of the two vertical plates (5), a motor (7) is fixedly connected onto the inner wall of the bottom of the equipment shell (1), a rotating shaft (8) is installed at the output end of the motor (7), a driving bevel gear (9) is connected onto the rotating shaft (8) through bolts, and driven bevel gears (10) are arranged on the front side and the back side, two worm (11) are installed to the one side that driven bevel gear (10) kept away from each other, every worm (11)'s below all is equipped with worm wheel (12), and has transmission shaft (13) through bolted connection on worm wheel (12), every equal swing joint has cleaning plate (14) on transmission shaft (13), and the below swing joint of cleaning plate (14) has dust collection box (15) that are located equipment shell (1) inside.

2. The cell separation device for the single cell transcriptome sequencing technology according to claim 1, wherein the top ends of the plurality of partition plates (6) are welded on the horizontal plate (4), the bottom ends of the partition plates (6) are welded on the inner wall of the bottom of the equipment housing (1), the inner wall of the middle part of the bottom of the equipment housing (1) is connected with the motor (7) through a bolt, and the top end of the rotating shaft (8) passes through the horizontal plate (4).

3. The cell separation device for the single-cell transcriptome sequencing technology according to claim 2, wherein one end of the worm (11) far away from the driven bevel gear (10) passes through the vertical plate (5) and is rotatably connected to the partition plate (6), and the driving bevel gear (9) and the driven bevel gear (10) are in mesh transmission.

4. The cell separation device for the single cell transcriptome sequencing technology of claim 3, wherein each worm (11) is installed with a fan blade, the worm (11) and the worm wheel (12) are also in meshed transmission, each partition plate (6) is provided with a first slot hole, and a filter screen plate is fixedly connected in the first slot hole.

5. The cell separation device for the single-cell transcriptome sequencing technology according to claim 4, wherein the front and back shell walls of the equipment housing (1) are respectively provided with a second slot hole, a heat dissipation plate is fixedly connected in the second slot hole, and two ends of the transmission shaft (13) are respectively rotatably connected to the inner walls of two sides of the equipment housing (1).

6. The cell separation device for the single-cell transcriptome sequencing technology according to claim 4, wherein a movable groove is opened on an outer surface of each transmission shaft (13), a connecting rod is slidably connected in the movable groove, a sliding groove located on the partition plate (6) is opened below the first groove hole, a sliding block is slidably connected in the sliding groove, and one end of the connecting rod far away from the transmission shaft (13) is welded on the sliding block.

7. The cell separation device for single-cell transcriptome sequencing technology of claim 6, wherein a fixed rod is welded on one side of each slide block far away from the connecting rod, and a cleaning plate (14) is welded on one end of each fixed rod far away from the slide block.

Technical Field

The invention relates to the technical field of cell separation, in particular to a cell separation device for a single-cell transcriptome sequencing technology.

Background

Centrifuges are machines that utilize centrifugal force to separate components of a mixture of liquid and solid particles or liquid and liquid. Sequencing of transcriptomes of single cells during biological studies requires their cell separation by the action of a centrifuge.

Centrifuge of cell separation can produce a large amount of heats at the in-process that uses, and current equipment relies on the installation fan to carry out wind-force heat dissipation basically in the processing that carries out the heat dissipation, and such heat dissipation mode not only structure is comparatively complicated, and the cost is higher, and the louvre of equipment needs the manual work to remove dust and clears up, and is comparatively troublesome. Therefore, how to process the cell separation apparatus becomes a problem to be solved urgently.

Disclosure of Invention

Objects of the invention

The invention provides a cell separation device for a single cell transcriptome sequencing technology, which realizes wind power heat dissipation on the interior of equipment without an additional driving device in the use process through the combination of various structures, reduces the structure, saves the cost, synchronously realizes dust cleaning on a heat dissipation plate while realizing the wind power heat dissipation, prevents the heat dissipation plate from being blocked due to adhesion of a large amount of dust, and prolongs the service life of the equipment.

(II) technical scheme

The invention provides a cell separation device for a unicellular transcriptome sequencing technology, which comprises an equipment shell, wherein a top cover is installed on the outer wall of the top of the equipment shell, a control panel is arranged on the wall of the front side of the equipment shell, a transverse plate is arranged inside the equipment shell, a plurality of vertical plates are welded between the transverse plate and the inner wall of the bottom of the equipment shell, a partition plate positioned inside the equipment shell is welded on one side, away from each other, of the two vertical plates, a motor is fixedly connected on the inner wall of the bottom of the equipment shell, a rotating shaft is installed at the output end of the motor, a driving bevel gear is connected on the rotating shaft through a bolt, driven bevel gears are respectively arranged on the front side and the back side of the driving bevel gear, worms are installed on one side, away from each other, a worm wheel is arranged below each, each transmission shaft is movably connected with a cleaning plate, and a dust collecting box positioned in the equipment shell is movably connected below the cleaning plate.

Preferably, it is a plurality of the top of baffle all welds on the diaphragm, and the bottom of baffle welds on equipment housing's bottom inner wall, there is the motor through bolted connection on the middle part inner wall of equipment housing bottom, the diaphragm is passed on the top of pivot.

Preferably, one end of the worm, which is far away from the driven bevel gear, penetrates through the vertical plate and is rotatably connected to the partition plate, and the driving bevel gear and the driven bevel gear are in meshing transmission.

Preferably, each worm is provided with a fan blade, the worm and the worm wheel are also in meshed transmission, each partition plate is provided with a first slotted hole, and the first slotted hole is fixedly connected with a filter screen plate.

Preferably, the front and back shell walls of the equipment shell are both provided with second slotted holes, the second slotted holes are fixedly connected with heat dissipation plates, and two ends of the transmission shaft are respectively rotatably connected to the inner walls of two sides of the equipment shell.

Preferably, every the surface of transmission shaft has all seted up the activity groove, and sliding connection has the connecting rod in the activity groove, the spout that is located on the baffle is seted up to the below of first slotted hole, and the inside sliding connection of spout has the slider, the one end that the transmission shaft was kept away from to the connecting rod welds on the slider.

Preferably, each slide block is kept away from one side of connecting rod and all welded the dead lever, and the dead lever is kept away from the one end welding of slide block and is had the clearance board.

Compared with the prior art, the technical scheme of the invention has the following beneficial technical effects:

1, make this device need not other drive arrangement in the use realize the wind-force heat dissipation to equipment inside through the combination of erection equipment shell, top cap, control panel, diaphragm, riser, baffle, motor, pivot, drive bevel gear and driven bevel gear isotructure, reduce the structure, practice thrift the cost.

2, make this device realize wind-force radiating while synchronous realization to the dust clearance of heating panel through the combination of installation worm, worm wheel, transmission shaft, cleaning plate and dust collection box isotructure, prevent that a large amount of dusts of its adhesion from blockking up, the life of extension equipment.

Drawings

FIG. 1 is a schematic structural diagram of a cell separation device for single-cell transcriptome sequencing technology according to the present invention.

FIG. 2 is a schematic side view, partially in section, of a cell separation device for single-cell transcriptome sequencing according to the present invention.

FIG. 3 is a schematic perspective view of a cell separation device for single-cell transcriptome sequencing according to the present invention.

Reference numerals: 1. an equipment housing; 2. a top cover; 3. a control panel; 4. a transverse plate; 5. a vertical plate; 6. a partition plate; 7. a motor; 8. a rotating shaft; 9. a drive bevel gear; 10. a driven bevel gear; 11. a worm; 12. a worm gear; 13. a drive shaft; 14. cleaning the plate; 15. a dust collecting box.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

As shown in FIGS. 1-3, the cell separation device for the single-cell transcriptome sequencing technology provided by the invention comprises an equipment housing 1, a top cover 2 is installed on the outer wall of the top of the equipment housing 1, a control panel 3 is arranged on the front shell wall of the equipment housing 1, a transverse plate 4 is arranged inside the equipment housing 1, a plurality of vertical plates 5 are welded between the transverse plate 4 and the inner wall of the bottom of the equipment housing 1, a partition plate 6 positioned inside the equipment housing 1 is welded on one side, away from each other, of the two vertical plates 5, a motor 7 is fixedly connected on the inner wall of the bottom of the equipment housing 1, a rotating shaft 8 is installed at the output end of the motor 7, a driving bevel gear 9 is connected on the rotating shaft 8 through bolts, driven bevel gears 10 are respectively arranged on the front surface and the back surface of the driving bevel gear 9, worms 11 are installed on one side, away from each driven bevel, and the worm wheel 12 is connected with transmission shafts 13 through bolts, each transmission shaft 13 is movably connected with a cleaning plate 14, and a dust collecting box 15 positioned in the equipment shell 1 is movably connected below the cleaning plate 14.

In an optional embodiment, the top ends of the partition plates 6 are welded on the transverse plate 4, the bottom ends of the partition plates 6 are welded on the inner wall of the bottom of the equipment shell 1, the motor 7 is connected to the inner wall of the middle of the bottom of the equipment shell 1 through a bolt, and the top end of the rotating shaft 8 penetrates through the transverse plate 4.

In an alternative embodiment, one end of the worm 11 far away from the driven bevel gear 10 penetrates through the vertical plate 5 and is rotatably connected to the partition plate 6, and the driving bevel gear 9 and the driven bevel gear 10 are in meshing transmission.

In an alternative embodiment, each worm 11 is provided with a fan blade, the worm 11 and the worm wheel 12 are in meshed transmission, each partition plate 6 is provided with a first slot hole, and a filter screen plate is fixedly connected in the first slot hole.

In an alternative embodiment, the front and back casing walls of the equipment casing 1 are respectively provided with a second slot, the second slot is fixedly connected with a heat dissipation plate, and two ends of the transmission shaft 13 are respectively rotatably connected to the inner walls of two sides of the equipment casing 1.

In an optional embodiment, an outer surface of each transmission shaft 13 is provided with a movable groove, the movable groove is slidably connected with a connecting rod, a sliding groove located on the partition board 6 is formed below the first groove hole, a sliding block is slidably connected inside the sliding groove, and one end, far away from the transmission shaft 13, of the connecting rod is welded on the sliding block.

In an alternative embodiment, a fixed rod is welded to one side of each slider away from the connecting rod, and a cleaning plate 14 is welded to one end of the fixed rod away from the slider.

The working principle is as follows: when equipment needs to be used, after preparation work is completed, the top cover 2 is closed, the motor 7 is started through the control panel 3, the rotating shaft 8 is driven to rotate, the driving bevel gear 9 rotates, meshing transmission is performed between the driving bevel gear 9 and the driven bevel gear 10, rotation of the worm 11 is further achieved, rotation of the fan blades is driven, air blowing is achieved, meshing transmission is performed between the worm 11 and the worm wheel 12, rotation of the transmission shaft 13 is driven, reciprocating motion of the cleaning plate 14 is achieved through combination of the connecting rod, the sliding block and the fixing plate through rotation of the transmission shaft 13, dust cleaning of the heat dissipation plate is achieved, part of dust cleaned on the heat dissipation plate is blown out of the outer portion of the equipment shell 1 through air blowing of the fan blades, and part of dust falls into the dust collection box 15, and the dust is cleaned through regular cleaning of the dust collection box 15.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used only for convenience of description and simplicity of description, and do not indicate or imply that the equipment or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be considered as limiting the present invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.