阅读说明：本技术 样本复检方法及样本分析仪 (Sample reinspection method and sample analyzer ) 是由 史立波 刘洋 肖培瑞 武振兴 刘鹤 王婧敏 于 2019-04-26 设计创作，主要内容包括：本发明提供一种样本复检方法及样本分析仪。该样本复检方法应用于样本分析仪,所述样本分析仪包括样本检测装置、第一进样装置、第二进样装置以及用于控制所述装置的控制器；所述第一进样装置将具有样本的样本容器输送至所述样本检测装置,所述样本检测装置检测所述样本得到第一检测结果；所述样本复检方法包括如下步骤：所述第二进样装置接受新放置的样本容器；所述控制器判断所述第二进样装置上样本容器中的样本为复检样本,所述第二进样装置将所述样本容器输送至所述样本检测装置,所述样本检测装置检测所述样本得到第二检测结果,所述控制器将所述第二检测结果作为所述样本的复检结果。实现复检样本的优先检测,缩短复检样本的等待时间。(The invention provides a sample reinspection method and a sample analyzer. The sample reinspection method is applied to a sample analyzer, wherein the sample analyzer comprises a sample detection device, a first sample introduction device, a second sample introduction device and a controller for controlling the devices; the first sample introduction device conveys a sample container with a sample to the sample detection device, and the sample detection device detects the sample to obtain a first detection result; the sample reinspection method comprises the following steps: the second sample introduction device receives a newly placed sample container; the controller judges that the sample in the sample container on the second sample introduction device is the reinspection sample, the second sample introduction device conveys the sample container to the sample detection device, the sample detection device detects the sample to obtain a second detection result, and the controller takes the second detection result as the reinspection result of the sample. The priority detection of the reinspection sample is realized, and the waiting time of the reinspection sample is shortened.)

1. The sample reinspection method is characterized by being applied to a sample analyzer, wherein the sample analyzer comprises a sample detection device, a first sample introduction device, a second sample introduction device and a controller for controlling the devices;

the first sample introduction device conveys a sample container with a sample to the sample detection device, and the sample detection device detects the sample to obtain a first detection result;

The second sample introduction device receives a newly placed sample container;

the controller judges that the sample in the sample container on the second sample introduction device is the reinspection sample, the second sample introduction device conveys the sample container to the sample detection device, the sample detection device detects the sample to obtain a second detection result, and the controller takes the second detection result as the reinspection result of the sample.

2. The method for retesting samples according to claim 1, wherein the sample analyzer includes a sample reading device;

the controller judges that the sample in the sample container on the second sample introduction device is a reinspection sample, and the method comprises the following steps:

the controller controls the sample reading device to read the identifier on the sample container on the second sample introduction device so as to obtain a sample ID corresponding to the sample;

and the controller judges that the sample is a retest sample according to the sample ID.

3. The method for retesting samples according to claim 2, wherein the controller determines the samples as retesting samples according to the sample IDs, comprising the steps of:

and the controller matches the sample ID in the detected sample data, and judges the sample as a retest sample corresponding to the sample ID after the matching is successful.

4. The method for reinspecting a sample according to claim 3, wherein the second sample introduction device further comprises, before receiving the newly placed sample container, the steps of: and the controller determines a sample ID corresponding to the sample needing to be retested from the detected sample data according to the user instruction, and enters a retesting program.

5. The method for reinspecting a sample according to claim 3, wherein the second sample introduction device further comprises, before receiving the newly placed sample container, the steps of: the controller establishes a new sample according to a user instruction, determines the corresponding position of the new sample in the second sample introduction device, and enters a detection program of the new sample;

the controller controls the sample reading device to read the identifier on the sample container on the second sample introduction device so as to obtain the sample ID corresponding to the sample, and the method comprises the following steps: the controller controls the sample reading device to read the identifier on the sample container at the corresponding position to obtain a sample ID corresponding to the sample, and the sample ID is used as the ID of the new sample.

6. The method for reinspecting a sample according to claim 1, wherein the controller determines that the sample in the sample container of the second sample feeding device is an reinspection sample, comprising the steps of: and the controller judges the sample in the sample container at the position corresponding to the second sample introduction device as a reinspection sample.

7. The method for reinspecting a sample according to claim 6, wherein before the second sample introduction device receives the newly placed sample container, the method further comprises the steps of: and the controller determines a sample ID corresponding to the sample needing to be retested in the detected sample data according to a user instruction, modifies the original position information of the sample needing to be retested into the corresponding position, and enters a retesting program.

8. The method for reinspecting a sample according to claim 6, wherein before the second sample introduction device receives the newly placed sample container, the method further comprises the steps of: and the controller establishes a new sample according to a user instruction, determines the corresponding position of the new sample in the second sample introduction device, takes the sample ID corresponding to the sample needing to be retested as the ID of the new sample according to the user instruction, and enters a detection program of the new sample.

9. The method for reinspecting a sample according to any one of claims 1 to 8, wherein the second sample feeding device further comprises, before the step of transporting the sample container to the sample testing device: the controller acquires the reinspection parameters input by a user;

the sample detection device detects the sample to obtain a second detection result, and comprises the following steps: and the sample detection device detects the sample according to the reinspection parameter and obtains the second detection result.

10. The method for retesting samples according to claim 9, wherein the retest parameters include one or more of sample size, reagent amount, dilution factor, and concentration factor.

11. The method of claim 9, wherein the user-entered review parameters are applicable to a plurality of review samples.

12. A sample analyzer, wherein the sample analyzer applies the sample reinspection method according to any one of claims 1 to 11, and the sample analyzer comprises a sample detection device, a first sample introduction device, a second sample introduction device, and a controller for controlling the devices;

the first sample introduction device and the second sample introduction device respectively convey a sample container with a sample to the sample detection device, and the sample detection device detects the sample.

Technical Field

The invention relates to the technical field of sample detection, in particular to a sample reinspection method and a sample analyzer.

Background

The blood coagulation detection has important reference value in auxiliary diagnosis of hemorrhagic diseases, thrombotic diseases, DIC and serious liver and kidney diseases, and also has important function in the detection of anticoagulation quality and preoperative examination, so that a blood coagulation analyzer becomes an indispensable examination device in clinical examination rooms such as hospitals and examination centers.

As the number of test items and test samples increases year by year, the accuracy and timeliness of tests required by doctors and patients are also increasing. To improve the efficiency of testing and the degree of automation of the instruments, these instruments have used a transport device that automatically sequentially transports the samples to the analysis area. The device generally comprises a loading area and an unloading area, wherein a user puts a sample in the loading area, the instrument automatically transports the sample to an analysis area of the instrument, and after the sample sampling is finished, the instrument automatically removes the sample and moves the sample to the next sample, so that the cycle is repeated until all samples are tested, and all samples are in the unloading area after the testing is finished.

Normally, the above-mentioned method is an efficient test method, but after being interfered by the sample itself and the abnormal factors of the analyzer itself, the test result may not be credible, for example, the sample concentration is too high and exceeds the measurement range of the analyzer, and the measurement needs to be re-performed after dilution, for example, when a reagent is added, air bubbles are introduced, which results in no result, and the like, in this case, a re-inspection may need to be performed, and then the user may determine the final report result according to the re-inspection result. However, the sample may have been removed by the sample transport device, so that the sample with a problem can be rechecked only after the batch of samples is tested, which results in that the sample cannot be reported in time, the detection time is too long, the rechecking efficiency is low, and a fatal risk may exist in serious cases.

Disclosure of Invention

Therefore, it is necessary to provide a sample retesting method and a sample analyzer capable of rapidly detecting a retested sample, aiming at the problem of too long waiting time of the retested sample at present.

The above purpose is realized by the following technical scheme:

a sample reinspection method is applied to a sample analyzer, and the sample analyzer comprises a sample detection device, a first sample introduction device, a second sample introduction device and a controller for controlling the devices;

the first sample introduction device conveys a sample container with a sample to the sample detection device, and the sample detection device detects the sample to obtain a first detection result;

the second sample introduction device receives a newly placed sample container;

the controller judges that the sample in the sample container on the second sample introduction device is the reinspection sample, the second sample introduction device conveys the sample container to the sample detection device, the sample detection device detects the sample to obtain a second detection result, and the controller takes the second detection result as the reinspection result of the sample.

In one embodiment, the sample analyzer comprises a sample reading device;

The controller judges that the sample in the sample container on the second sample introduction device is a reinspection sample, and the method comprises the following steps:

the controller controls the sample reading device to read the identifier on the sample container on the second sample introduction device so as to obtain a sample ID corresponding to the sample;

and the controller judges that the sample is a retest sample according to the sample ID.

In one embodiment, the controller determines that the sample is a retest sample according to the sample ID, including:

and the controller matches the sample ID in the detected sample data, and judges the sample as a retest sample corresponding to the sample ID after the matching is successful.

In one embodiment, before the second sample introduction device receives the newly placed sample container, the method further comprises the following steps: and the controller determines a sample ID corresponding to the sample needing to be retested from the detected sample data according to the user instruction, and enters a retesting program.

In one embodiment, before the second sample introduction device receives the newly placed sample container, the method further comprises the following steps: the controller establishes a new sample according to a user instruction, determines the corresponding position of the new sample in the second sample introduction device, and enters a detection program of the new sample;

The controller controls the sample reading device to read the identifier on the sample container on the second sample introduction device so as to obtain the sample ID corresponding to the sample, and the method comprises the following steps: the controller controls the sample reading device to read the identifier on the sample container at the corresponding position to obtain a sample ID corresponding to the sample, and the sample ID is used as the ID of the new sample.

In one embodiment, the controller determines that the sample in the sample container on the second sample introduction device is a retest sample, and includes the following steps: and the controller judges the sample in the sample container at the position corresponding to the second sample introduction device as a reinspection sample.

In one embodiment, before the second sample introduction device receives the newly placed sample container, the method further comprises the following steps: and the controller determines a sample ID corresponding to the sample needing to be retested in the detected sample data according to a user instruction, modifies the original position information of the sample needing to be retested into the corresponding position, and enters a retesting program.

In one embodiment, before the second sample introduction device receives the newly placed sample container, the method further comprises the following steps: and the controller establishes a new sample according to a user instruction, determines the corresponding position of the new sample in the second sample introduction device, takes the sample ID corresponding to the sample needing to be retested as the ID of the new sample according to the user instruction, and enters a detection program of the new sample.

In one embodiment, before the second sample introduction device delivers the sample container to the sample detection device, the method further comprises the following steps: the controller acquires the reinspection parameters input by a user;

the sample detection device detects the sample to obtain a second detection result, and comprises the following steps: and the sample detection device detects the sample according to the reinspection parameter and obtains the second detection result.

In one embodiment, the review parameters include one or more of sample size, reagent amount, dilution factor, and concentration factor.

In one embodiment, the user-entered review parameters are applicable to a plurality of review samples.

A sample analyzer, which applies the sample reinspection method according to any one of the above technical features, the sample analyzer comprising a sample detection device, a first sample introduction device, a second sample introduction device, and a controller for controlling the devices;

the first sample introduction device and the second sample introduction device respectively convey a sample container with a sample to the sample detection device, and the sample detection device detects the conveyed sample.

After the technical scheme is adopted, the invention at least has the following technical effects:

According to the sample reinspection method and the sample analyzer, the controller is used for judging whether the sample in the sample container of the second sample introduction device is the reinspection sample or not, then the sample detection device is used for detecting the sample in the sample container of the second sample introduction device to obtain a second detection result, and the controller is used for taking the second detection result as the reinspection result of the sample. The sample reinspection method realizes the prior detection of the reinspection sample by multiplexing the second sample feeding device, effectively solves the problem of overlong waiting time of the reinspection sample at present, ensures that the detection priority of the reinspection sample is higher than that of other samples, shortens the waiting time of the reinspection sample, ensures that the second detection result can be obtained in time, and avoids fatal risks caused by overlong detection time.

Drawings

FIG. 1 is a top view of a sample analyzer according to one embodiment of the present invention;

FIG. 2 is a flow chart of a sample review method according to an embodiment;

FIG. 3 is a flow chart of a sample review method according to another embodiment;

FIG. 4 is a schematic illustration of an interface for operation of the sample analyzer according to one embodiment, wherein the sample analyzer is shown in situ with a review sample;

FIG. 5 is a schematic view of an exemplary embodiment of an interface for operating a sample analyzer, wherein the view shows a new review sample;

FIG. 6 is a schematic diagram illustrating a first test result and a second test result displayed on an operation interface according to an embodiment;

FIG. 7 is a schematic view of an operation interface according to an embodiment, wherein the first detection result is taken as the detection result of the sample;

FIG. 8 is a schematic view of an operation interface according to an embodiment, wherein the second detection result is taken as the detection result of the sample;

fig. 9 is a schematic diagram of setting a review parameter displayed on an operation interface according to an embodiment.

Wherein:

100-a sample analyzer;

110-a first sample introduction device;

120-a second sample introduction device;

130-a sample detection device;

140-a sample reading device;

150-a sample loading zone;

160-sample unloading zone;

170-industrial personal computer.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more clearly apparent, the sample retesting method and the sample analyzer of the present invention are further described in detail by the following embodiments with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects as described, and does not have any sequential or technical meaning. The term "connected" and "coupled" when used in this application, unless otherwise indicated, includes both direct and indirect connections (couplings). In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations or positional relationships based on the orientations or positional relationships illustrated in the drawings, are only for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention.

In the present invention, unless otherwise expressly stated or limited, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through an intermediate. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.

Referring to fig. 1 to 3, the present invention provides a sample retest method, which is applied to a sample analyzer 100 for retesting a sample. It can be understood that, when the sample analyzer 100 performs analysis and detection on a sample to be detected, a detection result corresponding to the sample can be obtained, and the use requirement can be met. When the parameters of the sample are abnormal, such as the parameter values are higher and lower, the sample needs to be detected again, namely, the sample is subjected to rechecking, so that the deviation of the sample detection result caused by detection errors is avoided, and the accuracy of the sample detection result is ensured. The sample reinspection method can realize rapid reinspection of the sample to be reinspected, shorten the waiting time of the reinspection sample, timely obtain the detection result of the reinspection sample and avoid fatal risks caused by overlong detection time.

It should be noted that the specific type of sample to be tested is not limited, and in some embodiments, the sample to be tested includes a solid sample or a liquid sample. It can be understood that the liquid sample needs to be placed on the sample holder for detection. Further liquid samples include, but are not limited to, blood samples. When a blood sample is tested using the sample analyzer 100 of the present invention, the blood sample is stored in a sample container and sequentially placed on a sample rack. The sample analyzer 100 may be one of a coagulation analyzer, a hemocyte analyzer, a biochemical analyzer, and an immunoassay analyzer.

The sample analyzer 100 includes a sample detection device 130, a first sample introduction device 110, a second sample introduction device 120, and a controller (not shown) for controlling the devices. The controller may comprise a central processing unit CPU. In the present embodiment, the sample review method includes steps S10 to S30.

Step S10: the first sample introduction device 110 conveys the sample container with the sample to the sample detection device 130, and the sample detection device 130 detects the sample to obtain a first detection result. The sample analyzer 100 also has a sample loading area 150 and a sample unloading area 160. The sample loading zone 150 is used to carry a sample to be tested. It will be appreciated that the sample container carries the sample to be tested and that the sample container with the sample to be tested is carried by the sample rack. Optionally, one or more sample containers may be carried on the sample rack. Illustratively, a sample rack may carry five or ten sample containers. The first sample introduction device 110 is used for conveying the sample rack in the sample loading area 150, so as to realize the automatic conveying of the sample to be measured.

The sample detection device 130 is used for processing the sample in the sample container, detecting the sample, and obtaining a first detection result. Specifically, the sample testing device 130 may transfer the sample in the sample container at the sample sucking position (180 or 190), incubate the sample, and perform the testing on the sample. The sample detection device 130 illustratively includes a dispensing device 131, a sample incubation device 132, a detection device 133, and the like, wherein the dispensing device 131 transfers the sample transferred by the first sample introduction device 110 into a sample cup of the sample incubation device 132, incubates the sample by the sample incubation device 132, transfers the sample cup with the sample into the detection device 133, and detects the sample by the detection device 133 to obtain a detection result of the sample, and records the detection result as the first detection result. After the sample in the sample container on the first sample introduction device 110 is dispensed by the dispensing device 131 at the sample suction position 190, the sample rack is transferred to the sample unloading area 160, and the detected sample container is stored in the sample unloading area 160. In this embodiment, the dispensing device 131 includes a pipette needle, the sample incubation device 132 includes an incubation disk and a sample cup, and the detection device 133 includes a coagulation detector based on an optical method and/or a magnetic bead method.

If the first detection result of the sample is abnormal, the user can perform retest on the sample corresponding to the abnormal first detection result.

Step S20: the second sample introduction device 120 receives the newly placed sample container.

When the sample needs to be retested, the sample container corresponding to the sample stored in the sample unloading area 160 is transferred to the second sample injection device 120, and the sample to be tested is conveyed through the second sample injection device 120. It will be appreciated that the sample containers may be transferred manually, or may be transferred automatically, such as by automated transfer means such as a gripper. The second sample introduction device 120 may convey a retest sample, an emergency sample, or a mixture of the retest sample and the emergency sample.

The priority of the sample in the second sample introduction device 120 is higher than that of the sample in the first sample introduction device 110, and when the second sample introduction device 120 conveys the sample container, the first sample introduction device 110 stops conveying the sample container, so that the sample in the sample container of the second sample introduction device 120 can be preferentially detected, the detection efficiency is improved, and meanwhile, the interference between the first sample introduction device 110 and the second sample introduction device 120 is also avoided. In the sample reinspection method in this embodiment, the second sample injection device 120 (e.g., an emergency treatment module) for conveying the emergency treatment sample can be adopted to convey the reinspection sample, so that multiplexing of the second sample injection device 120 is realized, and no additional structure is required to be added while reinspecting the sample.

Step S30: the controller determines that the sample in the sample container on the second sample introduction device 120 is the retest sample, the second sample introduction device 120 conveys the sample container to the sample detection device 130, the sample detection device 130 detects the sample to obtain a second detection result, and the controller takes the second detection result as the retest result of the sample.

In the process of conveying the sample by the second sample introduction device 120, the controller determines whether the sample in the sample container of the second sample introduction device 120 is a retest sample. If the controller determines that the sample in the sample container of the second sample introduction device 120 is the retest sample, the second sample introduction device 120 conveys the sample container to the sample detection device 130, the sample detection device 130 transfers, incubates, detects, etc. the sample in the sample container to obtain a second detection result of the sample, and the controller takes the second detection result as the retest result of the sample. The position where the sample detection device 130 transfers the sample in the sample container on the second sample introduction device 120 is the sample sucking position 180.

If the controller determines that the sample in the sample container on the second sample injection device 120 is not a retest sample but an emergency new sample, at this time, the second sample injection device 120 conveys the sample container corresponding to the emergency new sample to the sample detection device 130, and the sample detection device 130 transfers, incubates, detects, etc. the emergency new sample in the sample container to obtain a detection result of the emergency new sample.

The sample reinspection method of the above embodiment implements reinspection of the reinspected sample by multiplexing the second sample introduction device 120, and since the priority of the sample in the second sample introduction device 120 is higher than the priority of the sample in the first sample introduction device 110, the first sample introduction device 110 stops conveying while the second sample introduction device 120 conveys the sample container, so as to perform rapid detection on the reinspected sample. The problem that the waiting time of the current reinspection sample is too long is effectively solved, so that the detection priority of the reinspection sample is higher than that of other common samples, the waiting time of the reinspection sample is shortened, the reinspection efficiency is improved, the second detection result can be obtained in time, and the fatal risk caused by the overlong detection time is avoided.

It is understood that the sample retest method of the present invention can determine whether the sample is a retest sample by the sample reading device 140; when the sample reading device 140 is not used or can not be used (for example, the sample container lacks an identifier such as a barcode), the retest sample can also be determined by the position information, and the following two cases are described separately:

in case 1, the controller determines whether or not the sample in the sample container is a retest sample by the sample reading device 140, as will be described below. In one embodiment, the sample analyzer 100 includes a sample reading device 140; the controller determines that the sample in the sample container on the second sample introduction device 120 is a retest sample, and the method comprises the following steps: the controller controls the sample reading device 140 to read the identifier on the sample container on the second sample introduction device 120 to obtain the sample ID (identification number) corresponding to the sample; and the controller judges the sample to be a rechecking sample according to the sample ID.

The sample reading device 140 may illustratively be a scanner for reading indicia on the sample container, it being understood that the indicia may be a bar code, two-dimensional code, or other identifiable indicia.

In the process of conveying the sample container by the second sample introduction device 120, the controller controls the identifier of the sample container of the sample reading device 140, and can obtain the sample ID corresponding to the sample according to the identifier, and then the controller determines whether the sample is the retest sample according to the sample ID. If so, when the sample detection device 130 detects the sample, the controller takes the detection result as a second detection result of the sample; if not, when the sample detection device 130 detects the sample, the controller takes the detection result as the first detection result of the sample.

In an embodiment, the step of determining, by the controller, that the sample is a retest sample according to the sample ID specifically includes the steps of: and the controller matches the sample ID in the detected sample data, and judges the sample as a retest sample corresponding to the sample ID after the matching is successful.

After the controller obtains the sample ID, the controller searches and matches the detected sample data, if the sample ID can be matched, the sample is indicated to be a retest sample, and the sample is judged to be the retest sample corresponding to the sample ID; if the sample ID cannot be matched, the sample is a new sample, for example, an emergency sample.

The user operates through the user operation interface, the sample needing to be retested can be set as the retest sample, a new sample can be created, and then the new sample is associated with the sample needing to be retested. The following examples are given.

A case where a sample requiring review is set as a review sample will be described. In one embodiment, before the second sample introduction device 120 receives the newly placed sample container, the method further includes the following steps: and the controller determines a sample ID corresponding to the sample needing to be retested from the detected sample data according to the user instruction, and enters a retesting program. After entering the rechecking procedure, the second sample introduction device 120 receives the newly placed sample container; the controller determines that the sample in the sample container on the second sample introduction device 120 is the retest sample, the second sample introduction device 120 conveys the sample container to the sample detection device 130, the sample detection device 130 detects the sample to obtain a second detection result, and the controller takes the second detection result as the retest result of the sample.

In this embodiment, the user may directly set the sample corresponding to the first detection result as the review sample through operation. Before transferring the sample container in the sample unloading area 160 to the second sample injection device 120, the user may mark the sample with the abnormal first detection result as a review sample on the user operation interface, and then transfer the sample container corresponding to the sample to the second sample injection device 120. Specifically, the sample to be retested is marked as a retest sample in situ on the operator interface of the sample analyzer 100. As shown in fig. 4, the abnormal first detection result is found, the sample corresponding to the first detection result is clicked, and then the review button is clicked to enter the review program. It can be understood that the operation interface of the sample analyzer 100 is displayed by the industrial personal computer 170 of the sample analyzer 100, and the user can input a corresponding program through the industrial personal computer 170 to control the operation of the sample analyzer 100.

Next, a case will be described in which a new sample is created and then the new sample is associated with a sample that needs to be reviewed. In another embodiment, before the second sample introduction device 120 receives the newly placed sample container, the method further comprises the following steps: the controller establishes a new sample according to the user instruction, determines the corresponding position of the new sample in the second sample introduction device 120, and enters a detection procedure for the new sample. After entering the detection procedure for the new sample, the second sample introduction device 120 receives the newly placed sample container; the controller determines that the sample in the sample container on the second sample introduction device 120 is the retest sample, the second sample introduction device 120 conveys the sample container to the sample detection device 130, the sample detection device 130 detects the sample to obtain a second detection result, and the controller takes the second detection result as the retest result of the sample. In this case, the controller controls the sample reading device 140 to read the identifier on the sample container on the second sample introduction device 120 to obtain the sample ID corresponding to the sample, which specifically includes the following steps: the controller controls the sample reading device 140 to read the identifier on the sample container at the corresponding position to obtain the sample ID corresponding to the sample, and uses the sample ID as the ID of the new sample.

In this embodiment, a new sample is created as a retest sample, and the retest sample is associated with a sample with an abnormal first detection result. Before the sample container in the sample unloading area 160 is transferred to the second sample introduction device 120, a new sample is created according to the user's instruction. As shown in fig. 5, a user creates a new sample (for example, the sample with serial number 1 in fig. 5) on the operation interface of the sample analyzer 100, and at this time, the controller automatically generates the position information of the new sample in the second sample injection device 120 (for example, the position information I in the sample with serial number 1 in fig. 5), so that the user can place the sample container to be retested at the position of the second sample injection device.

The sample container corresponding to the sample in the sample unloading area 160 is transferred to the second sample injection device 120, and during the process of transporting the sample container by the second sample injection device 120, the sample reading device 140 reads the identifier of the sample container at the corresponding position of the second sample injection device 120 to obtain the corresponding sample ID. Then, the controller automatically fills the sample ID into the new sample location as the new sample ID of the new sample (e.g. the sample number information in fig. 5 is consistent with the sample number corresponding to serial number 96 to be retested), and then the user clicks the test button (not shown in the figure) to test the sample to be retested on the second sample injection device 120. In this way, the detection result of the sample needing to be retested on the second sample injection device 120 can be displayed at the new sample on the operation interface of the sample analyzer 100. The sample ID of the sample needing to be retested is the same as the new sample ID, which indicates that the detection result of the new sample is the retest result of the original sample.

In case 2, when the sample reading device 140 is not in use or is not usable (e.g., the sample container lacks an identifier such as a barcode), the controller determines the retest sample from the position information, as illustrated below.

In one embodiment, the controller determines that the sample in the sample container of the second sample feeding device 120 is a retest sample, including the steps of: the controller determines the sample in the sample container located at the position corresponding to the second sample introduction device 120 as the retest sample. Similar to the above embodiment, in this embodiment, the user operates through the user operation interface, and may set the sample to be retested as the retest sample, or create a new sample, and then associate the new sample with the sample to be retested. The following examples are given.

A case where a sample requiring review is set as a review sample will be described.

In one embodiment, before the second sample introduction device 120 receives the newly placed sample container, the method further includes the following steps: and the controller determines a sample ID corresponding to the sample needing to be retested from the detected sample data according to the user instruction, modifies the original position information of the sample needing to be retested into a corresponding position, and enters a retesting program. After entering the rechecking procedure, the second sample introduction device 120 receives the newly placed sample container; the controller determines that the sample in the sample container on the second sample introduction device 120 is the retest sample, the second sample introduction device 120 conveys the sample container to the sample detection device 130, the sample detection device 130 detects the sample to obtain a second detection result, and the controller takes the second detection result as the retest result of the sample.

That is, the sample ID corresponding to the sample to be retested is determined in the detected sample data, the user directly modifies the original position information (e.g., sample position 16-9 with serial number 96 in fig. 4) of the sample to be retested into the corresponding position that the user of the second sample injection device 120 wants to place on the operation interface of the sample analyzer 100, and then clicks the retest button to enter the retest procedure. Then, the controller controls the sample container at the corresponding position on the second sample introduction device 120 to the sample detection device 130, and the sample detection device 130 detects and obtains a second detection result. Finally, the second detection result is attributed to the sample ID. At this time, the sample ID has two detection results, which are the first detection result and the second detection result, respectively, and the user can compare the first detection result with the second detection result and determine that the first detection result or the second detection result is used as the detection result of the sample ID. As shown in fig. 6, the history review interface shows that the sample ID has two detection results, namely a first detection result (result 1) and a second detection result (result 2). If the user takes the first detection result as the final detection result of the sample ID, the operation is performed as shown in FIG. 7, and the numerical value selection box corresponding to the click result 1 is reported; if the user uses the second detection result as the final detection result of the sample ID, the operation is performed as shown in fig. 8, and the numerical value selection box corresponding to the click result 2 is reported.

Next, a case will be described in which a new sample is created and then the new sample is associated with a sample that needs to be reviewed. Referring to fig. 1 to 3, in another embodiment, before the second sample introduction device 120 receives the newly placed sample container, the method further includes the steps of: the controller establishes a new sample according to the user instruction, determines the corresponding position of the new sample in the second sample introduction device 120, and enters a detection procedure for the new sample by taking the sample ID corresponding to the sample needing to be retested as the ID of the new sample according to the user instruction. After entering the detection procedure for the new sample, the second sample introduction device 120 receives the newly placed sample container; the controller determines that the sample in the sample container on the second sample introduction device 120 is the retest sample, the second sample introduction device 120 conveys the sample container to the sample detection device 130, the sample detection device 130 detects the sample to obtain a second detection result, and the controller takes the second detection result as the retest result of the sample.

In this embodiment, a new sample is created as a retest sample, and the retest sample is associated with a sample with an abnormal first detection result. Before the sample container in the sample unloading area 160 is transferred to the second sample introduction device 120, a new sample is created according to the user's instruction. As shown in fig. 5, a user creates a new sample (for example, the sample with serial number 1 in fig. 5) on the operation interface of the sample analyzer 100, and at this time, the controller automatically generates the position information of the new sample in the second sample introduction device 120 (for example, the position information I in the sample with serial number 1 in fig. 5), so that the user can place the sample container to be retested at this position.

The sample container corresponding to the sample in the sample unloading area 160 is transferred to the second sample injection device 120, and then the user fills the sample ID to be retested into the new sample ID by itself, and then clicks a test button (not shown) to test the sample to be retested on the second sample injection device 120. In this way, the detection result of the sample needing to be retested on the second sample injection device 120 can be displayed at the new sample on the operation interface of the sample analyzer 100. The ID of the sample needing to be retested is the same as the ID of the new sample, so that the detection result of the new sample is the retest result of the original sample.

Whether the sample needing to be retested is set as the retest sample or a new sample is created and then associated with the sample needing to be retested, the retest parameters can be set separately for the retest sample before the retest. The following examples are given.

In one embodiment, before the second sample introduction device 120 delivers the sample container to the sample detection device 130, the method further includes the steps of: the controller acquires the reinspection parameters input by the user. In this case, the step of detecting the sample by the sample detection device 130 to obtain the second detection result includes the following steps: the sample detection device 130 detects the sample according to the reinspection parameter and obtains a second detection result.

That is, the specimen subjected to the review operation can independently set the review parameters. For example, when the sample amount in the sample container is small, the sample amount and other related parameters can be modified, so that air suction or suction of other foreign matters influencing the test is avoided; for another example, when it is determined that the sample concentration is high, a corresponding dilution factor or the like may be set according to the first detection result, so that the report can be made after one retest. After the parameters of the sample for reinspection are independently set, the efficiency can be improved, and the cost can be saved.

Specifically, when the first detection result is determined to be abnormal, the user considers that the sample corresponding to the first detection result needs to be retested, the sample container corresponding to the sample is transferred to the second sample introduction device 120, the retest parameter corresponding to the sample is reset on the operation interface of the sample analyzer 100, then the retest button (corresponding to the case where the sample needing to be retested is set as the retest sample) or the detection button (corresponding to the case where a new sample is created and then the new sample is associated with the sample needing to be retested) is clicked, the second sample introduction device 120 starts to convey the sample, and the retest operation of the sample is realized. The sample detection device 130 performs detection according to the retest parameter corresponding to the sample to obtain a second detection result of the sample.

Optionally, the review parameters include one or more of sample size, reagent amount, dilution factor, and concentration factor. Of course, the review parameter may also be other detection parameters.

In one embodiment, the review parameters entered by the user are applicable to a plurality of review samples. The second sample introduction device 120 can deliver one review sample or a plurality of review samples at a time, and the user can apply the review parameters to the plurality of review samples through one input. It can be understood that, when a plurality of samples need to be retested at the same time, after all retested samples are set, the sample containers corresponding to the samples are transferred to the second sample injection device 120 at a time, and then the second sample injection device 120 is started. In addition, in the process of retest, a sample container with a retest sample or an emergency sample may be newly added to the second sample injection device 120.

As shown in fig. 9, when the parameters are set independently, a sample to be retested is selected from the operation interface of the sample analyzer 100, the sample and the information of the sample detection items (for example, the detection items such as APTT/PT/TT/FIB/D-D/FDP/AT-iii shown in the right column of fig. 4) are clicked, and then the parameter setting button is clicked to open the parameter setting interface, AT this time, the retest parameters of the sample can be adjusted according to the actual test requirements. For one sample, the user can select a plurality of detection items to be retested for retesting.

In the embodiment of the present invention, during a normal test process of the sample analyzer 100, the first sample introduction device 110 conveys the sample container to the sample detection device 130 for detection, so as to obtain a first detection result of the sample. When the user finds that the first detection result of the sample is abnormal and needs to be retested, the retest sample needs to be set first, and then the sample container corresponding to the retest sample is transferred to the second sample introduction device 120. And starting the second sample introduction device 120, stopping sample introduction by the first sample introduction device 110, and completing the detection of the samples on the second sample introduction device 120 one by the sample detection device 130. After the retest, the first sample injection device 110 resumes the sample injection and continues to perform the sample detection.

Referring to fig. 1 to 3, the present invention further provides a sample analyzer 100, the sample analyzer 100 employs the sample reinspection method in any of the above embodiments, and the sample analyzer 100 includes a sample detection device 130, a first sample introduction device 110, a second sample introduction device 120, and a controller for controlling these devices. The first sample introduction device 110 and the second sample introduction device 120 respectively convey a sample container with a sample to the sample detection device 130, the sample detection device 130 detects the sample to obtain a detection result, and the industrial personal computer 170 outputs the result according to the detection result.

The first sample introduction device 110 conveys the sample container with the sample to the sample detection device 130, and the sample detection device 130 detects the sample to obtain a first detection result. The sample analyzer 100 also has a sample loading area 150 and a sample unloading area 160. The sample loading zone 150 is used to carry a sample to be tested. The sample detection device 130 is used for processing the sample, detecting the sample, and obtaining a first detection result. It is understood that the structure and the working procedure of the sample detection device 130 have been mentioned above, and are not described herein again.

When the first detection result is abnormal, the user or the sample analyzer 100 transfers the sample container of the sample corresponding to the first detection result to the second sample injection device 120, and the second sample injection device 120 conveys the retest sample, and at the same time, the first sample injection device 110 stops injecting the sample, and the sample detection device 130 processes and detects the sample in the second sample injection device 120 to obtain a second detection result, and the second detection result is used as the retest result of the sample.

In one embodiment, when the sample analyzer 100 is started, it is first determined whether the second sample injection device 120 delivers the sample, and if so, the second sample injection device 120 performs the sample injection operation; if not, the first sample introduction device 110 performs a sample introduction operation. After the second sample introduction device 120 performs the sample introduction operation, the controller determines whether there is a measurable sample in the second sample introduction device 120, if so, the sample is tested by the sample detection device 130, and if not, the sample introduction is resumed by the first sample introduction device 110, and the sample introduction operation is performed. The controller determines whether there is a measurable sample in the first sample injection device 110, if so, the sample detection device 130 tests the sample, and if not, the test is terminated or whether the second sample injection device 120 performs sample injection is determined again. After the sample testing by the sample testing device 130 is completed, the sample analyzer 100 terminates the test.

The present application also provides a coagulation analyzer of an embodiment, wherein the sample analyzer of the above-mentioned embodiment is a coagulation analyzer for measuring and analyzing coagulation/anticoagulation and fibrinolysis/antifibrinolysis functions of a sample, and a coagulation time method is a measuring method for measuring a coagulation process of a sample as a change of transmitted light or a change of movement of magnetic beads in a sample under magnetic driving. The items measured by the coagulation time method include PT (prothrombin time), APTT (activated partial thrombin time), TT (thrombin time), FIB (fibrinogen amount), and the like.

Reference is made herein to various exemplary embodiments. However, those skilled in the art will recognize that changes and modifications may be made to the exemplary embodiments without departing from the scope hereof. For example, the various operational steps, as well as the components used to perform the operational steps, may be implemented in differing ways depending upon the particular application or consideration of any number of cost functions associated with operation of the system (e.g., one or more steps may be deleted, modified or incorporated into other steps).

Additionally, as will be appreciated by one skilled in the art, the principles herein may be reflected in a computer program product on a computer readable storage medium, which is pre-loaded with computer readable program code. Any tangible, non-transitory computer-readable storage medium may be used, including magnetic storage devices (hard disks, floppy disks, etc.), optical storage devices (CD-ROMs, DVDs, Blu Ray disks, etc.), flash memory, and/or the like. These computer program instructions may be loaded onto a general purpose computer, special purpose computer, or other programmable data processing apparatus to produce a machine, such that the instructions which execute on the computer or other programmable data processing apparatus create means for implementing the functions specified. These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including means for implementing the function specified. The computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified.

While the principles herein have been illustrated in various embodiments, many modifications of structure, arrangement, proportions, elements, materials, and components particularly adapted to specific environments and operative requirements may be employed without departing from the principles and scope of the present disclosure. The above modifications and other changes or modifications are intended to be included within the scope of this document.

The foregoing detailed description has been described with reference to various embodiments. However, one skilled in the art will recognize that various modifications and changes may be made without departing from the scope of the present disclosure. Accordingly, the disclosure is to be considered in an illustrative and not a restrictive sense, and all such modifications are intended to be included within the scope thereof. Also, advantages, other advantages, and solutions to problems have been described above with regard to various embodiments. However, the benefits, advantages, solutions to problems, and any element(s) that may cause any element(s) to occur or become more pronounced are not to be construed as a critical, required, or essential feature or element of any or all the claims. As used herein, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, system, article, or apparatus.

The technical features of the embodiments described above can be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the present invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.