Stem cell storage device
阅读说明:本技术 一种干细胞储藏设备 (Stem cell storage device ) 是由 陈龙刚 于 2020-08-13 设计创作,主要内容包括:本发明公开了一种干细胞储藏设备,属于干细胞储藏技术领域,包括储藏筒、输气装置、转动装置、旋转装置、升降装置和拿取开关装置,所述储藏筒的顶部设有开口,所述输气装置设置在储藏筒的旁侧,所述输气装置的一端贯穿储藏筒的顶部,所述转动装置设置在储藏筒的内底部,所述旋转装置设置在转动装置上,所述旋转装置与转动装置转动配合,所述升降装置设置在储藏筒的内侧壁上,所述升降装置的一端贯穿储藏筒且升降装置与储藏筒滑动配合,所述拿取开关装置设置在储藏筒的顶部,所述拿取开关装置与储藏筒转动配合。本发明通过提供一种干细胞储藏装置,使干细胞冻存更加均匀,同时在对干细胞拿取和摆放时,不再需要把手伸进深低温的储藏箱内。(The invention discloses stem cell storage equipment, which belongs to the technical field of stem cell storage and comprises a storage barrel, a gas transmission device, a rotating device, a lifting device and a taking switch device, wherein an opening is formed in the top of the storage barrel, the gas transmission device is arranged beside the storage barrel, one end of the gas transmission device penetrates through the top of the storage barrel, the rotating device is arranged at the inner bottom of the storage barrel, the rotating device is arranged on the rotating device, the rotating device is in rotating fit with the rotating device, the lifting device is arranged on the inner side wall of the storage barrel, one end of the lifting device penetrates through the storage barrel, the lifting device is in sliding fit with the storage barrel, the taking switch device is arranged at the top of the storage barrel, and the taking switch device is in rotating fit with the storage barrel. The stem cell storage device provided by the invention enables the stem cells to be frozen more uniformly, and meanwhile, when the stem cells are taken and placed, a handle is not required to extend into a storage box at a deep low temperature.)
1. The stem cell storage equipment is characterized by comprising a storage barrel (1), a gas transmission device (2), a rotating device (3), a rotating device (4), a lifting device (5) and a taking switch device (6), wherein the storage barrel (1) is vertically placed on the ground, the interior of the storage barrel (1) is of a hollow structure, an opening is formed in the top of the storage barrel (1), the gas transmission device (2) is arranged beside the storage barrel (1), one end of the gas transmission device (2) penetrates through the top of the storage barrel (1), the rotating device (3) is arranged at the inner bottom of the storage barrel (1), the rotating device (4) is arranged on the rotating device (3), the rotating device (4) is in rotating fit with the rotating device (3), the lifting device (5) is arranged on the inner side wall of the storage barrel (1), one end of the lifting device (5) penetrates through the storage barrel (1) and the lifting device (5) and the storage barrel (1) The storage barrel is in sliding fit, the taking switch device (6) is arranged at the top of the storage barrel (1), and the taking switch device (6) is in running fit with the storage barrel (1).
2. A stem cell storage device as defined in claim 1, wherein: gas transmission device (2) are including liquid nitrogen case (21), defeated nitrogen pipe (22), support frame (23) and aspiration pump (24), liquid nitrogen case (21) set up the side at storage cylinder (1), the one end and liquid nitrogen case (21) of defeated nitrogen pipe (22) are linked together, the other end of defeated nitrogen pipe (22) runs through storage cylinder (1), be equipped with a plurality of air vents on the other end of defeated nitrogen pipe (22), support frame (23) are vertical places subaerial, the top at support frame (23) is installed in aspiration pump (24).
3. A stem cell storage device as defined in claim 1, wherein: rotating device (3) include rolling disc (31), running gear (32) and first rotation motor (33), rolling disc (31) set up the inside at storage cylinder (1), rolling disc (31) and storage cylinder (1) normal running fit, running gear (32) set up the bottom at rolling disc (31), running gear (32) and rolling disc (31) fixed connection, the trailing end connection of first rotation motor (33) is in the interior bottom of storage cylinder (1), the one end of first rotation motor (33) runs through running gear (32) and both transmissions are connected, the main shaft and the rolling disc (31) of first rotation motor (33) are connected.
4. A stem cell storage device as claimed in claim 3, wherein: the rotating device (4) comprises six rotating assemblies (41), each rotating assembly (41) is arranged around a rotating gear (32) and comprises a rotating gear (42), a bearing circular seat (43), four supporting rods (44), four fixing springs (45) and four arc-shaped plates (46), the rotating gear (42) comprises a bottom end arranged on a rotating disc (31), the rotating gear (42) is meshed with the rotating gear (32), the bearing circular seat (43) is arranged on the rotating disc (31), one end of the bearing circular seat (43) is in transmission connection with the rotating gear (42) and the other end of the bearing circular seat (43) penetrates through the rotating disc (31), the bearing circular seat (43) is in running fit with the rotating disc (31), and the supporting rods (44) are arranged on the top end of the bearing circular seat (43), four the one end of fixed spring (45) is horizontal connection respectively on the top inner wall of four bracing pieces (44), four arc (46) are connected respectively at the other end of four fixed spring (45), four still be equipped with four sheets of rubber on the lateral wall of arc (46).
5. A stem cell storage device as defined in claim 1, wherein: the lifting device (5) comprises a lifting base (51), a lifting threaded rod (52), a lifting motor (53), a lifting moving base (54), a clamping fixing base (55), a clamping motor (56), two hinging blocks (57), two clamping gears (58) and two annular clamping rings (59), wherein the lifting base (51) is fixedly arranged on the inner wall of the storage barrel (1), the two ends of the lifting threaded rod (52) are rotatably connected with the two ends of the lifting base (51), the lifting motor (53) is arranged at the top of the storage barrel (1), a main shaft of the lifting motor (53) penetrates through the storage barrel (1) and the lifting base (51), the main shaft of the lifting motor (53) is in transmission connection with the lifting threaded rod (52), the lifting moving base (54) is arranged on the lifting threaded rod (52), and the lifting moving base (54) is in threaded connection with the lifting threaded rod (52), the lifting moving seat (54) is in sliding fit with the lifting base (51), the hinging blocks (57) are arranged on two sides of the top of the lifting moving seat (54), the annular clamp taking rings (59) are hinged to the hinging blocks (57) respectively, the clamping gears (58) are connected to the bottoms of the rotating ends of the annular clamp taking rings (59) in a transmission mode respectively, the clamping gears (58) are meshed with each other, the clamping fixing seat (55) is arranged at the bottom of the lifting moving seat (54), the tail end of the clamping motor (56) is connected to the bottom of the clamping fixing seat (55) and the main shaft of the clamping motor (56) is arranged upwards, and the main shaft of the clamping motor (56) is in transmission connection with one of the clamping gears (58).
6. A stem cell storage device as defined in claim 1, wherein: the taking switch device (6) comprises a sliding rod (61), a switch fixing seat (62), a second rotating motor (63), a rotating wheel (64), two hinged rod assemblies (65), two pulleys (66), two fan-shaped blocks (651), two connecting ropes (67), a plurality of sliding rings (652) and a plurality of closed springs (68), wherein the sliding rod (61) is horizontally arranged at the side of an opening, the two hinged rod assemblies (65) are connected to the sliding rod (61) through the plurality of sliding rings (652), one ends of the two hinged rod assemblies (65) are respectively connected to the two ends of the sliding rod (61), the two hinged rod assemblies (65) are composed of a plurality of hinged rods which are hinged in pairs, the sliding rings (652) are in sliding fit with the sliding rod (61), and the plurality of closed springs (68) are respectively arranged between the two hinged rods which are hinged in pairs, the two fan-shaped blocks (651) are respectively connected to a sliding ring (652) connected with the other ends of the two hinge rod assemblies (65), the two fan-shaped blocks (651) are in sliding fit with the storage barrel (1), the rotating wheel (64) is arranged on the storage barrel (1), the rotating wheel (64) is in rotating fit with the storage barrel (1), the switch fixing seat (62) is arranged at the top of the storage barrel (1), the tail end of the second rotating motor (63) is arranged on the inner wall of the top of the switch fixing seat (62), the main shaft of the second rotating motor (63) is connected to the rotating wheel (64), the two pulleys (66) are arranged at the top end of the storage barrel (1) and located on two sides of the sliding rod (61), the two pulleys (66) are in sliding fit with the storage barrel (1), one end of the two connecting ropes (67) is respectively connected with the other ends of the two hinge rod assemblies (65), the other end of two connecting rope (67) is connected in rotating wheel (64) through two pulley (66) respectively, two connecting rope (67) are at the same time contract and relax under the rotation of rotating wheel (64).
Technical Field
The invention relates to the technical field of stem cell storage, in particular to stem cell storage equipment.
Background
Stem cells are a type of pluripotent cells with self-renewal ability, and are a type of primitive cells with self-replication and multipotentiality, i.e., stem cells that maintain an unoriented differentiation state and have proliferation ability, and under appropriate conditions or given appropriate signals, can differentiate into various functional cells or tissue organs, which are called "universal cells" in medical science.
In the stem cell storage, the stem cells are separated and cultured from different human tissues, and then are detected and identified, and then are frozen at the deep low temperature of-196 ℃, so that the stem cells can be revived for reinfusion to patients when clinically needed, and the purpose of treating diseases is achieved.
When the stem cells are stored at low temperature, the stem cells are often taken and placed at the temperature of-196 ℃ by carrying tools, the convenience is low, the danger degree is extremely high, and meanwhile, the stem cells cannot be fully frozen under the protection of a vessel during the storage of the stem cells.
Disclosure of Invention
The invention aims to provide stem cell storage equipment to solve the technical problems that stem cells are not uniformly frozen and a handle needs to be stretched into a deep low temperature when the stem cells are taken and placed in the prior art.
In order to solve the technical problems, the invention provides the following technical scheme: the utility model provides a stem cell storage equipment, includes storage section of thick bamboo, gas transmission device, rotating device, rotary device, elevating gear and the switching device of taking, storage section of thick bamboo is vertical places subaerial, storage section of thick bamboo inside is hollow structure, storage section of thick bamboo's top is equipped with the opening, gas transmission device sets up the side at storage section of thick bamboo, gas transmission device's one end runs through storage section of thick bamboo's top, rotating device sets up the interior bottom at storage section of thick bamboo, rotary device sets up on rotating device, rotary device and rotating device normal running fit, elevating gear sets up on storage section of thick bamboo's inside wall, storage section of thick bamboo and elevating gear and storage section of thick bamboo sliding fit are run through to elevating gear's one end, the switching device of taking sets up at storage section of thick bamboo's top, switching device and storage section of thick bamboo normal running fit take.
Further, the gas transmission device comprises a liquid nitrogen box, a nitrogen transmission pipe, a support frame and an air pump, wherein the liquid nitrogen box is arranged beside the storage barrel, one end of the nitrogen transmission pipe is communicated with the liquid nitrogen box, the other end of the nitrogen transmission pipe penetrates through the storage barrel, a plurality of air holes are formed in the other end of the nitrogen transmission pipe, the support frame is vertically placed on the ground, and the air pump is arranged at the top of the support frame.
Further, rotating device includes rolling disc, rolling gear and first rotation motor, the rolling disc sets up the inside at a storage section of thick bamboo, rolling disc and storage section of thick bamboo normal running fit, rolling gear sets up the bottom at the rolling disc, rolling gear and rolling disc fixed connection, the trailing end connection of first rotation motor is in the interior bottom of a storage section of thick bamboo, the one end of first rotation motor runs through rolling gear and both transmission are connected, the main shaft and the rolling disc of first rotation motor are connected.
Further, the rotating device comprises six rotating assemblies, each rotating assembly is arranged around a rotating gear, each rotating assembly comprises a rotating gear, a bearing circular seat, four supporting rods, four fixed springs and four arc-shaped plates, the rotating gear comprises a gear body which is arranged at the bottom end of the rotating disc and is meshed with the rotating gear, the bearing circular seat is arranged on the rotating disc, one end of the bearing circular seat is connected to the rotating gear in a transmission way, the other end of the bearing circular seat penetrates through the rotating disc, bear circle seat and rolling disc normal running fit, four the bracing piece all is around setting up on the top of bearing the circle seat, four fixed spring's one end difference horizontal connection is on the top inner wall of four bracing pieces, four the arc is connected respectively at four fixed spring's the other end, four still be equipped with four rubber sheets on the lateral wall of arc.
Further, the lifting device comprises a lifting base, a lifting threaded rod, a lifting motor, a lifting moving seat, a clamping fixing seat, a clamping motor, two hinging blocks, two clamping gears and two annular clamping rings, the lifting base is fixedly arranged on the inner wall of the storage barrel, two ends of the lifting threaded rod are rotatably connected with two ends of the lifting base, the lifting motor is arranged at the top of the storage barrel, a main shaft of the lifting motor penetrates through the storage barrel and the lifting base, the main shaft of the lifting motor is in transmission connection with the lifting threaded rod, the lifting moving seat is arranged on the lifting threaded rod, the lifting moving seat is in threaded connection with the lifting threaded rod, the lifting moving seat is in sliding fit with the lifting base, the two hinging blocks are arranged at two sides of the top of the lifting moving seat, and the two annular clamping rings are respectively hinged on the two hinging blocks, two press from both sides the gear and connect in the bottom of the rotation end of two ring clamps ring of getting respectively the transmission, two press from both sides and get gear both intermeshing, press from both sides the bottom that the fixing base set up at the lift removal seat of getting, press from both sides the trailing end connection of getting the motor and press from both sides the bottom of getting the fixing base and press from both sides the main shaft of getting the motor and upwards set up, press from both sides the main shaft of getting the motor and press from both sides gear drive with one.
Furthermore, the taking switch device comprises a sliding rod, a switch fixing seat, a second rotating motor, a rotating wheel, two hinged rod assemblies, two pulleys, two fan-shaped blocks, two connecting ropes, a plurality of sliding rings and a plurality of closing springs, wherein the sliding rod is horizontally arranged beside the opening, the two hinged rod assemblies are connected to the sliding rod through the plurality of sliding rings, one ends of the two hinged rod assemblies are respectively connected to two ends of the sliding rod, the two hinged rod assemblies comprise a plurality of hinge rods hinged in pairs, the plurality of sliding rings are in sliding fit with the sliding rods, the plurality of closing springs are respectively arranged between the two hinge rods hinged in pairs, the two fan-shaped blocks are respectively connected to the sliding rings connected to the other ends of the two hinged rod assemblies, the two fan-shaped blocks are both in sliding fit with the storage barrel, the rotating wheel is arranged on the storage barrel, the utility model discloses a motor, including a storage section of thick bamboo, the rotation wheel and a storage section of thick bamboo, the switch fixing base sets up the top at the storage section of thick bamboo, the second rotates the tail end setting of motor on the top inner wall of switch fixing base, the second rotates the main shaft connection of motor and takes turns to, two on the rotation wheel the pulley setting just is located the both sides of slide bar, two on the top of storage section of thick bamboo pulley and storage section of thick bamboo sliding fit, two the other end of two articulated pole subassemblies is connected respectively, two to the one end of connecting rope connect in the rotation wheel through two pulleys respectively, two the connecting rope is simultaneously contracted and relaxed under the rotation of rotation wheel.
Compared with the prior art, the invention has the beneficial effects that:
firstly, when stem cells are stored, a first rotating motor starts to operate to drive a rotating gear to start to operate, and simultaneously a rotating disc starts to operate to drive a vessel containing the stem cells and stored in a storage cylinder to slowly rotate, so that the stem cells are uniformly frozen under the protection of the vessel by liquid nitrogen in the storage cylinder, the survival rate of the stem cells is improved, the economic efficiency is improved, the vessel containing the stem cells is fixed by four supporting rods and four arc plates under the coordination of four fixing springs, a rubber sheet prevents the vessel containing the stem cells from slipping, when a rotating device starts to rotate, the rotating gear drives the rotating gear and the rotating disc to do differential rotation, the rotating gear drives a bearing circular seat to slowly rotate, the four supporting rods and the four arc plates drive the vessel containing the stem cells to start to rotate under the coordination of the four fixing springs, the stem cells are evenly frozen by liquid nitrogen in the storage cylinder under the protection of the vessel, and the survival rate of the stem cells is improved.
Secondly, when the vessel containing the stem cells needs to be lifted, the lifting motor starts to operate to drive the lifting threaded rod to operate, the lifting moving seat starts to move up and down under the rotation of the lifting threaded rod, the clamping motor operates to drive the two clamping gears to rotate, the two clamping gears rotate to drive the two annular clamp rings to clamp, the vessel containing the stem cells is lifted automatically, the phenomenon that a human hand stretches into deep low temperature to operate is avoided, and the danger is reduced.
Thirdly, when the opening needs to be opened and closed, the second rotating motor starts to operate to contract and open the two connecting ropes, so that the two hinged rod assemblies drive the fan-shaped blocks to close and open the opening under the action of the two connecting ropes, the two fan-shaped blocks have closed elastic potential energy under the action of the two hinged rod assemblies and the plurality of closing springs, and when the second rotating motor controls the rotating wheel to loosen the two connecting ropes, the two fan-shaped blocks are closed under the action of the two hinged rod assemblies and the plurality of closing springs.
Drawings
FIG. 1 is a schematic perspective view of the present invention;
FIG. 2 is a partial perspective view of the first embodiment of the present invention;
FIG. 3 is a partial perspective view of the second embodiment of the present invention;
FIG. 4 is a third schematic view of a partial perspective structure of the present invention;
FIG. 5 is a schematic perspective view of the lifting device of the present invention;
FIG. 6 is an enlarged view taken at A in FIG. 5;
fig. 7 is a schematic perspective view illustrating the pickup switch device of the present invention.
The reference numbers in the figures are:
the device comprises a storage cylinder 1, a gas conveying device 2, a
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
In the description of the present invention, it is to be understood that the terms "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, are merely for convenience of description of the present invention, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.
Referring to fig. 1 to 7, the present invention provides a stem cell storage device, including a storage barrel 1, a gas transmission device 2, a
The gas transmission device 2 comprises a
The rotating
The
The
The taking switch device 6 comprises a sliding rod 61, a switch fixing seat 62, a second rotating motor 63, a rotating wheel 64, two hinged rod assemblies 65, two pulleys 66, two fan-shaped blocks 651, two connecting ropes 67, a plurality of sliding rings 652 and a plurality of closing springs 68, wherein the sliding rod 61 is horizontally arranged at the side of an opening, the two hinged rod assemblies 65 are connected to the sliding rod 61 through the plurality of sliding rings 652, one end of each of the two hinged rod assemblies 65 is respectively connected to two ends of the sliding rod 61, each of the two hinged rod assemblies 65 is composed of a plurality of hinged rods hinged in pairs, the plurality of sliding rings 652 are in sliding fit with the sliding rod 61, the plurality of closing springs 68 are respectively arranged between the two hinged rod assemblies in pairs, the two fan-shaped blocks 651 are respectively connected to the sliding rings 652 connected to the other ends of the two hinged rod assemblies 65, and both the two fan-shaped blocks 651 are in sliding fit with the storage barrel 1, the rotating wheel 64 is arranged on the storage barrel 1, the rotating wheel 64 is in running fit with the storage barrel 1, the switch fixing seat 62 is arranged at the top of the storage barrel 1, the tail end of the second rotating motor 63 is arranged on the inner wall of the top of the switch fixing seat 62, the main shaft of the second rotating motor 63 is connected to the rotating wheel 64, the two pulleys 66 are arranged at the top end of the storage barrel 1 and located at two sides of the sliding rod 61, the two pulleys 66 are in running fit with the storage barrel 1, one end of each of the two connecting ropes 67 is connected with the other end of each of the two hinge rod assemblies 65, the other ends of the two connecting ropes 67 are connected to the rotating wheel 64 through the two pulleys 66, and the two connecting ropes 67 are simultaneously contracted and relaxed under the rotation of the rotating wheel 64; when the opening needs to be opened and closed, the second rotating motor 63 starts to operate to contract and open the two connecting ropes 67, so that the two hinged rod assemblies 65 drive the fan-shaped blocks 651 to close and open the opening under the action of the two connecting ropes 67, meanwhile, under the action of the two hinged rod assemblies 65 and the plurality of closing springs 68, the two fan-shaped blocks 651 have closed elastic potential energy, and when the second rotating motor 63 controls the rotating wheel 64 to loosen the two connecting ropes 67, the two fan-shaped blocks 651 are closed under the action of the two hinged rod assemblies 65 and the plurality of closing springs 68.
The working principle of the invention is as follows: liquid nitrogen is stored in the
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.
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