阅读说明：本技术 双杂环取代的吡啶-2(1h)-酮衍生物、其制法与医药上的用途 (Biheterocyclic substituted pyridine-2 (1H) -ketone derivative, preparation method and medical application thereof ) 是由 胡斌 朱经峰 方志华 杨斐 林崇懒 华默嘉 刘洋 关慧平 于 2019-11-11 设计创作，主要内容包括：提供双杂环取代的吡啶-2(1H)-酮衍生物、其制法与医药上的用途。具体地,提供式(Ⅱ)化合物或其药学上可接受的盐、立体异构体或溶剂化物,及其制备方法和应用。<Image he="370" wi="700" file="DDA0002643286580000011.GIF" imgContent="drawing" imgFormat="GIF" orientation="portrait" inline="no"></Image>(Provides a bi-heterocyclic substituted pyridine-2 (1H) -ketone derivative, a preparation method and a medical application thereof. Specifically, provided are compounds of formula (II) or pharmaceutically acceptable salts, stereoisomers or solvates thereof, and methods of preparation and use thereof.)