阅读说明：本技术 一种鳄鱼提取物在抗菌中的应用 (Application of crocodile extract in antibiosis ) 是由 张树华 于 2020-05-11 设计创作，主要内容包括：本发明提供一种鳄鱼提取物在制备抗菌药物中的应用方法,属于动物油脂精制技术领域,所述的鳄鱼提取物是鳄鱼油,鳄鱼油由以下方法制得,先通过对鳄鱼脂肪进行水解得到鳄鱼粗油,再对鳄鱼粗油使用碱性乙醇进行萃取,最后过滤和离心纯化得到鳄鱼精提油,具有制作流程简单、低成本和具有一定的抗菌活性的优点。(The invention provides an application method of crocodile extract in preparation of antibacterial drugs, which belongs to the technical field of refining of animal fat, wherein the crocodile extract is crocodile oil, and the crocodile oil is prepared by the following method, first, crocodile fat is hydrolyzed to obtain crocodile crude oil, then, the crocodile crude oil is extracted by using alkaline ethanol, and finally, crocodile refined oil is obtained by filtering and centrifugal purification.)

1. An application of crocodile extract in preparing antibacterial medicine is provided.

2. The use of crocodile extract according to claim 1, wherein the crocodile extract is crocodile essential oil.

3. The use of crocodile extract according to claim 2, wherein the crocodile essence oil is prepared by the steps of:

step S1, taking crocodile fat to hydrolyze to obtain crocodile crude oil;

step S2, extracting the crocodile crude oil prepared in the step S1 by using an alkaline ethanol solution, and filtering to obtain crocodile oil filtrate;

step S3, washing the crocodile oil filtrate obtained in step S2 with distilled water for multiple times;

and step S4, centrifuging and layering the crocodile oil filtrate washed in the step S3, and taking a grease layer to obtain crocodile essential oil.

4. The use of crocodile extract according to claim 3, wherein the alkaline ethanol in step S2 is an 80% ethanol solution with pH 9.0.

5. The use of crocodile extract according to claim 3, wherein 2 alkaline ethanol solution extractions are performed in step S2.

6. The use of crocodile extract according to claim 3, wherein the washing in step S3 is performed 3 times with distilled water.

Technical Field

The invention belongs to the technical field of animal fat refining, and particularly relates to an application of a crocodile extract in antibiosis.

Background

Crocodile is an amphibian reptile of the phylum chordata, class reptilia, order alligata and is one of the oldest animals that survive to date. The crocodile whole body is treasure, and has extremely high scientific research and development utilization values. The crocodile skin is a high-grade leather raw material, and tissues and organs such as crocodile meat, oil, blood, liver, gallbladder, nails, palms and the like have important medicinal health-care functions. Crocodiles are used as novel economic breeding animals and are bred artificially in a large amount in China, Guangdong provinces, Hainan provinces and the like. The comprehensive development and utilization of the artificially cultured crocodile have important economic, social and environmental benefits.

Alligator oil has been used for centuries in medicine for the treatment of a variety of conditions ranging from skin disorders to cancer. The compendium of materia Medica records: chinese alligator (crocodile) fat is used for treating dermatoses and malignant sore. Modern researches show that the crocodile oil has the effects of preventing frostbite, promoting skin wound healing, reducing scar formation, delaying skin aging, improving the activity of superoxide dismutase of skin cells, reducing the lipofuscin content of skin tissues and refreshing the brain. Therefore, the alligator oil has wide application in medical health care products and functional skin care products.

The different animal fat has larger component difference, and the required extraction and refining methods and processes thereof are different. Crocodile is a novel breeding economic animal developed in recent years, research on extraction and refinement methods and processes of crocodile oil is few, and particularly, the crocodile oil contains a large amount of polyene unsaturated fatty acids with medical and health care functions, is easy to oxidize and decompose, and the preparation of high-quality crocodile oil with complete bioactive components is very important for extraction and refinement of crocodile oil.

Disclosure of Invention

Based on the current situation, the invention provides an application method of an alligator extract in preparation of an antibacterial drug, wherein the alligator extract is crocodile oil, and the crocodile oil is prepared by the following method.

The invention achieves the above purpose through the following detailed technical scheme:

an application of crocodile extract in preparing antibacterial medicine is provided.

Wherein the crocodile extract is crocodile essential oil.

Wherein the crocodile essential oil is prepared by the following steps:

step S1, taking crocodile fat to hydrolyze to obtain crocodile crude oil;

step S2, extracting the crocodile crude oil prepared in the step S1 by using an alkaline ethanol solution, and filtering to obtain crocodile oil filtrate;

step S3, washing the crocodile oil filtrate obtained in step S2 with distilled water for multiple times;

and step S4, centrifuging and layering the crocodile oil filtrate washed in the step S3, and taking a grease layer to obtain crocodile essential oil.

Wherein the alkaline ethanol in the step S2 is 80% ethanol solution with pH of 9.0.

Wherein, the step S2 is carried out 2 times of alkaline ethanol solution extraction.

Wherein, the step S3 is performed by washing 3 times with distilled water.

The invention has the following beneficial effects: the crocodile essential oil has certain activity in the aspect of antibiosis, and the crocodile essential oil prepared by the method disclosed by the invention is applied to the preparation of an antibacterial drug, so that the preparation cost of the drug can be reduced.

Detailed Description

The present invention will be described in detail with reference to specific examples.