阅读说明：本技术 一种带有闭合功能的口服解毒活性炭 (Oral detoxification activated carbon with closing function ) 是由 李芝宏 于 2020-04-29 设计创作，主要内容包括：一种带有闭合功能的口服解毒活性炭,包括活性炭微粒、闭合涂层、吸附孔隙,所述活性炭微粒用于吸附有害物质,所述闭合涂层用于闭合活性炭空隙,所述吸附孔隙用于容纳有害物质。一种防止吸附的有害物质重新释放的口服解毒活性炭用于提高口服解毒活性炭的疗效。(The oral detoxification activated carbon with the closing function comprises activated carbon particles, a closing coating and adsorption pores, wherein the activated carbon particles are used for adsorbing harmful substances, the closing coating is used for closing the activated carbon pores, and the adsorption pores are used for containing the harmful substances. An oral detoxication activated carbon for preventing the re-release of adsorbed harmful substances is used to improve the curative effect of the oral detoxication activated carbon.)

1. The oral detoxification activated carbon with the closing function comprises activated carbon particles, a closing coating and adsorption pores, wherein the activated carbon particles are used for adsorbing harmful substances, the closing coating is used for closing the activated carbon pores, and the adsorption pores are used for containing the harmful substances.

2. The activated carbon particle of claim 1 having a porous structure therein for adsorbing and containing a harmful substance.

3. The closure coating of claim 1 wherein the primary component is precipitated silica.

4. The detoxified charcoal for oral administration with occlusive function as claimed in claim 1, wherein the detoxified charcoal is orally available.

5. The detoxified activated carbon for oral administration with a closing function as claimed in claim 1, wherein the detoxified activated carbon is encapsulated in a capsule and administered orally.

6. The oral detoxification activated carbon with the closing function is characterized in that a closing coating which swells when meeting water is arranged on the surface of activated carbon particles, the activated carbon particles swell after absorbing target substances, and the expanded closing coating blocks and closes adsorption pores on the surface of the activated carbon particles.

7. The oral detoxification activated carbon with a closing function according to claim 6, wherein the activated carbon particles are soaked in liquid precipitated silica, and after being taken out, the dried activated carbon particles are dried to solidify and shrink the precipitated silica at the pore edges of the activated carbon particles, and the dried and shrunk precipitated silica adheres to the pore edges of the surfaces of the activated carbon particles and exposes the adsorption pores of the surfaces of the activated carbon particles.

8. The oral detoxification activated carbon with the closing function is characterized in that a closing coating layer can not seal adsorption pores on the surfaces of activated carbon particles under a dry environment, the closing coating layer is distributed along the edges of the pores of the activated carbon particles, reaction expansion can be carried out only after water is met, and the adsorption pores on the surfaces of the activated carbon particles are closed after the volume of the expanded closing coating layer is increased.

9. The oral detoxification activated carbon with a closing function according to claim 8, wherein the precipitated silica is disposed on the surface of the activated carbon particles, and the adsorption pores on the surface of the activated carbon particles are reserved, and after entering the body, the precipitated silica reacts with gastric juice and gastric acid in the body and expands, and the expanded precipitated silica coating volume is increased to close the adsorption pores on the surface of the activated carbon particles to close the adsorption pores of the activated carbon particles.

10. An oral detoxication active carbon with a closing function is characterized in that a closing coating is used for blocking adsorption pores of active carbon particles and preventing harmful substances adsorbed by the pores of the active carbon particles from being absorbed when entering the alimentary canal of the next stage.

Technical Field

The invention relates to an oral detoxification activated carbon with a closing function.

Background

Activated carbon has long been used as an oral medicine, and is a use method which utilizes the activated carbon to adsorb toxic substances in digestive organs and discharge the toxic substances out of the body along with excrement. Is mainly used for preventing the absorption of various poisons clinically and has good effect on the treatment of gastrointestinal diseases. The active carbon can be used as oral medicine for treating various diseases, such as poisoning, emesis, nausea, diarrhea, intestinal flatulence, etc.

Gastric lavage is widely used as the first means of rescuing poisoning, but studies of the results of clinical treatment of patients taking overdose of medication also clearly show no beneficial effect. In recent years, activated carbon has been widely recognized as an inexpensive, convenient, nontoxic, and effective oral antidote, and particularly when poisoning by any poison is not known, the use of activated carbon as an antidote is not replaced by any medicine. The activated carbon is mainly used for detoxifying toxic symptoms such as morphine, atropine, mercurous chloride and the like, and when excessive poisoning occurs, the activated carbon is taken to prevent the absorption of medicines and poisons. Because of the limited dosage of activated carbon, the ideal treatment would be to first empty the stomach and then adsorb it with activated carbon. However, after the stomach adsorbs harmful substances, the activated carbon enters the digestive tract of the next stage along the digestive system. After the active carbon adsorbing harmful substances enters the digestive tract of the next stage, the harmful substances are released under the action of body fluid and a digestive system again, so that the harmful substances are absorbed by a human body, and the detoxification effect is greatly reduced. An oral detoxication activated carbon for preventing adsorbed harmful substances from being released again when entering the digestive system of the next stage is used for improving the curative effect of the oral detoxication activated carbon and has great significance on medical application.

Disclosure of Invention

The technical problem to be solved by the invention is to provide the oral detoxification activated carbon which prevents adsorbed harmful substances from being released again when entering the digestive system of the next stage.

The technical scheme for solving the technical problems is as follows:

the oral detoxification activated carbon with the closing function comprises activated carbon particles, a closing coating and adsorption pores, wherein the activated carbon particles are used for adsorbing harmful substances, the closing coating is used for closing the activated carbon pores, and the adsorption pores are used for containing the harmful substances.

The active carbon particles have porous structures and are used for adsorbing and containing harmful substances.

The main component of the closed coating is precipitated silica.

The oral detoxification activated carbon with the closing function is characterized by playing a role in oral administration.

The oral detoxification activated carbon with the closing function is characterized in that the oral detoxification activated carbon is encapsulated by capsules and is taken orally.

The oral detoxification activated carbon with the closing function is characterized in that a closing coating which swells when meeting water is arranged on the surface of activated carbon particles, the activated carbon particles swell after absorbing target substances, and the expanded closing coating blocks and closes adsorption pores on the surface of the activated carbon particles.

The oral detoxification activated carbon with the closing function is characterized in that activated carbon particles are soaked in liquid precipitated silica, the liquid precipitated silica is taken out and dried to enable the precipitated silica to be solidified and shrunk at the pore edges of the activated carbon particles, and the shrunk precipitated silica is attached to the pore edges of the surfaces of the activated carbon particles after drying treatment and exposes adsorption pores on the surfaces of the activated carbon particles.

The oral detoxification activated carbon with the closing function is characterized in that a closing coating layer can not seal adsorption pores on the surfaces of activated carbon particles under a dry environment, the closing coating layer is distributed along the edges of the pores of the activated carbon particles, reaction expansion can be carried out only after water is met, and the adsorption pores on the surfaces of the activated carbon particles are closed after the volume of the expanded closing coating layer is increased.

The oral detoxification activated carbon with the closing function is characterized in that precipitated silica is arranged on the surface of activated carbon particles, adsorption pores on the surface of the activated carbon particles are reserved, the precipitated silica reacts with gastric juice and gastric acid in vivo after entering the body and expands, and the expanded precipitated silica coating closes the adsorption pores on the surface of the activated carbon particles after the volume of the precipitated silica coating is increased to seal the adsorption pores of the activated carbon particles.

An oral detoxication active carbon with a closing function is characterized in that a closing coating is used for blocking adsorption pores of active carbon particles and preventing harmful substances adsorbed by the pores of the active carbon particles from being absorbed when entering the alimentary canal of the next stage.

The invention has the beneficial effects that: after the active carbon enters the human body and adsorbs harmful substances, the closed coating expands and closes pores of the active carbon, so that the harmful substances are locked in the adsorption pores of the active carbon particles, and the active carbon particles are prevented from being released and absorbed again when passing through other digestive tracts. Greatly improves the curative effect of the high-oral detoxification activated carbon.

Furthermore, the invention can also be applied to other scenes in which the release of the activated carbon after adsorption needs to be prevented, and the adsorption effect of the activated carbon is greatly improved.

According to one aspect of the invention, the oral detoxification activated carbon with the closing function is characterized in that a closing coating which swells when meeting water is arranged on the surface of activated carbon particles, the activated carbon particles swell after adsorbing a target substance, and the expanded closing coating blocks and closes adsorption pores on the surface of the activated carbon particles. The process is simple, the cost is low, the closing effect after expansion is good, as long as the activated carbon particles are still in the body, the closed coating is always in an expansion state under the internal moisture environment, and the harmful substances can be firmly locked in the activated carbon particles to prevent the harmful substances from being released and absorbed again.

According to one aspect of the invention, the oral detoxification activated carbon with the closing function is characterized in that the closing coating does not seal adsorption pores on the surfaces of activated carbon particles in a dry environment of the activated carbon, the closing coating is distributed along the edges of the pores of the activated carbon particles and undergoes reaction expansion after encountering water, and the expanded closing coating closes the adsorption pores on the surfaces of the activated carbon particles after increasing in volume. The adsorption capacity of the active carbon particles is kept in a dry state, and the active carbon particles expand and close adsorption pores after adsorption. The detoxification capability of the active carbon is maintained, and the closure can be continuously maintained in the environment with much moisture in the body.

According to one aspect of the present invention, an oral detoxication activated carbon with a closure function is characterized in that a closure coating is used to seal off pores of the activated carbon, thereby preventing harmful substances adsorbed by the pores of the activated carbon from being absorbed when entering the digestive tract of the next stage. After the active carbon adsorbs harmful substances, the adsorption pores are closed and blocked, the harmful substances are locked inside the active carbon particles, and the active carbon particles are prevented from being released and absorbed again when passing through other digestive tracts. Greatly improves the detoxification efficacy of the high oral detoxification activated carbon.

Drawings

FIG. 1 is an open schematic diagram schematically illustrating a preferred embodiment of the present invention;

FIG. 2 is a schematic diagram schematically illustrating a closed schematic of a preferred embodiment of the present invention;

the list of components represented by the various reference numbers in the figures is as follows:

(1) the coating comprises (1) a closed coating, (2) adsorption pores, (3) carbon, (4) closed gaps, (5) harmful substances, and (10) activated carbon particles with a closing function.

Detailed description of the invention

The principles and features of this invention are described below in conjunction with the following drawings, the examples of which are set forth to illustrate the invention and are not intended to limit the scope of the invention.

In part of the unclosed principle, as shown in fig. 1, the main component of the activated carbon particle 10 with the closed function is carbon 3, and the inside of the activated carbon particle 10 with the closed function is provided with a plurality of adsorption pores 2, and the adsorption pores 2 of the activated carbon particle 10 with the closed function have adsorption effect on other particles which can enter the pores. The method for coating the closed coating 1 on the outside of the activated carbon particle 10 with the closing function mainly comprises the steps of soaking the activated carbon particle 10 in liquid precipitated silica, taking out the liquid precipitated silica, drying the liquid precipitated silica to solidify and shrink the precipitated silica on the edge of the adsorption pore 2 on the surface of the activated carbon particle, adhering the dried and shrunk precipitated silica (the closed coating 1) to the edge of the pore on the surface of the activated carbon particle 10 with the closing function, and exposing the adsorption pore 2 on the surface of the activated carbon particle 10 with the closing function, wherein the dried activated carbon particle 10 with the closing function is in a dry state, so that the closed coating 1 is not expanded, the adsorption pore 2 retains the adsorption capacity, and the particles (harmful substances 5) capable of entering the adsorption pore 2 have the adsorption and retention effects. Partially based on the closed principle, as shown in fig. 2, after oral administration, the activated carbon particles 10 with the closed function enter the human body and are released in the stomach of the human body by matching with a capsule or other means for releasing the medicament at a fixed point, the activated carbon particles 10 with the closed function start to adsorb the harmful substances 5 through the adsorption effect of the adsorption pores 2 in the stomach, and the harmful substances 5 enter the adsorption pores 2 under the adsorption effect of the adsorption pores 2. The closed coating 1 is contacted with gastric juice and gastric acid water in a human body, a water absorption expansion effect is generated, the volume of the expanded closed coating 1 begins to increase, and the closed coating 1 with the increased volume forms a closed gap 4 to lock the harmful substances 5 in the adsorption pores 2. Because the closed coating 1 is made of the acid and alkali corrosion resistant precipitated silica material, the closed coating 1 can bear the corrosion and digestion of gastric acid and intestinal tract environment and still keeps a closed state, so that harmful substances 5 are prevented from being released again and absorbed by the intestinal tract when the activated carbon particles 10 with a closing function pass through a digestive system of the next stage, and the effect of enhancing the curative effect is further achieved.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and all such modifications, equivalents, improvements, etc. that are within the spirit and scope of the present invention are therefore intended to be included therein.