阅读说明：本技术 用于用抗cd22免疫治疗来治疗癌症的组合物和方法 (Compositions and methods for treating cancer with anti-CD22 immunotherapy ) 是由 里马斯·J·奥伦塔什 迪娜·施奈德 博罗·德罗普利奇 迪米特尔·S·迪米特罗夫 朱忠玉 于 2018-10-16 设计创作，主要内容包括：公开了包含CD22抗原结合结构域的嵌合抗原受体(CAR)。还公开了涉及CAR的核酸、重组表达载体、宿主细胞、抗原结合片段和药物组合物。还公开了在对象中治疗或预防癌症的方法,以及制备CAR T细胞的方法。(Chimeric Antigen Receptors (CARs) comprising a CD22 antigen binding domain are disclosed. Also disclosed are nucleic acids, recombinant expression vectors, host cells, antigen-binding fragments, and pharmaceutical compositions that relate to the CARs. Also disclosed are methods of treating or preventing cancer in a subject, and methods of making CAR T cells.)