阅读说明：本技术 一种药用粉剂的抗静电高阻隔的阴阳包装袋及其制备方法 (Antistatic high-barrier yin-yang packaging bag for medicinal powder and preparation method thereof ) 是由 高红军 郑永森 王树钊 周利辉 何展华 杨泓 薛奕鑫 蔡晓琳 于 2020-06-06 设计创作，主要内容包括：本发明涉及包装袋生产技术领域,公开了一种药用粉剂的抗静电高阻隔的阴阳包装袋及其制备方法,其制备方法包括以下步骤：S1、把乙烯和醋酸乙烯共聚得到乙烯—醋酸乙烯共聚物；S2、将乙烯—醋酸乙烯共聚物基醇解成乙烯—乙烯醇共聚物；S3、把S2得到的乙烯—乙烯醇共聚物研磨成粉料；S4、把S3得到粉料加工成塑料薄膜；S5、喷镀防静电剂Ⅱ形成透明层；S6、把铝箔卷裁喷涂导电油墨形成铝箔层。本发明通过把乙烯—醋酸乙烯共聚物中的乙酰基醇解成羟基,得到乙烯—乙烯醇共聚物,使其具有高阻隔性能,通过在乙烯—乙烯醇共聚物内添加防静电剂I以及表面喷涂防静电剂Ⅱ,可以大大提高透明层的抗静电效果,通过在铝箔层的表面喷涂导电油墨,使其具有良好防静电性能。(The invention relates to the technical field of packaging bag production, and discloses an antistatic high-barrier yin-yang packaging bag of medicinal powder and a preparation method thereof, wherein the preparation method comprises the following steps: s1, copolymerizing ethylene and vinyl acetate to obtain an ethylene-vinyl acetate copolymer; s2, alcoholysis of the ethylene-vinyl acetate copolymer base to obtain ethylene-vinyl alcohol copolymer; s3, grinding the ethylene-vinyl alcohol copolymer obtained in the step S2 into powder; s4, processing the powder obtained in the step S3 into a plastic film; s5, spraying an antistatic agent II to form a transparent layer; and S6, cutting the aluminum foil roll and spraying conductive ink to form the aluminum foil layer. According to the invention, acetyl in the ethylene-vinyl acetate copolymer is alcoholyzed into hydroxyl to obtain the ethylene-vinyl alcohol copolymer, so that the ethylene-vinyl alcohol copolymer has high barrier property, the antistatic agent I is added into the ethylene-vinyl alcohol copolymer, and the antistatic agent II is sprayed on the surface of the ethylene-vinyl alcohol copolymer, so that the antistatic effect of the transparent layer can be greatly improved, and the conductive ink is sprayed on the surface of the aluminum foil layer, so that the aluminum foil layer has good antistatic property.)

1. The utility model provides an antistatic high resistant negative and positive wrapping bag of pharmaceutical powder and preparation method thereof, includes aluminium foil layer (1) and welds stratum lucidum (3) in aluminium foil layer (1) upper end through the hot melt mode, the inboard of handing-over department of aluminium foil layer (1) and stratum lucidum (3) is provided with self-supporting zip fastener (2), and the one end of aluminium foil layer (1) and stratum lucidum (3) is close to the front end of self-supporting zip fastener (2) and has seted up hand tear mouth (4), its characterized in that, its preparation method includes following step:

s1, mixing ethylene and vinyl acetate according to a ratio of 25:75, taking methanol as a solvent, and carrying out free radical copolymerization on the vinyl acetate and the ethylene as monomers in a reaction kettle to obtain an ethylene-vinyl acetate copolymer;

s2, adding methanol, sodium hydroxide and the ethylene-vinyl acetate copolymer into a reaction kettle according to the ratio of 55:8:37, filling nitrogen into the reaction kettle to discharge oxygen in the reaction kettle, then, starting a vacuum pump to pump the reaction kettle to form negative pressure, heating and stirring the reaction kettle, properly supplementing the methanol in the heating process, continuously pumping the vacuum pump to ensure that the negative pressure in the reaction kettle is not changed, discharging methanol steam and byproducts through the vacuum pump, and carrying out alcoholysis on acetyl in the ethylene-vinyl acetate copolymer to form hydroxyl so as to obtain the ethylene-vinyl alcohol copolymer;

s3, filtering, cleaning and drying the ethylene-vinyl alcohol copolymer obtained in the step S2, adding an additive, a plasticizer, an antistatic agent I and ethylene-vinyl alcohol into the copolymer according to the proportion of 3:14:5:78, mixing, and grinding into powder;

s4, putting the powder obtained in the step S3 into an internal mixer for plastication and mixing to form plastic slices, processing the plastic slices into plastic particles through a double-screw extruder, and processing the plastic particles into a plastic film through a film blowing machine;

s5, spraying an antistatic agent II on the plastic film obtained in the step S4 through a film plating machine, and cutting the plastic film into a set shape to form a transparent layer (3);

s6, cutting the aluminum foil roll into the size same as that of the transparent layer, spraying conductive ink on the surface to form an aluminum foil layer (1), respectively adhering the self-standing zipper (2) on the aluminum foil layer (1) and the transparent layer (3), and welding the transparent layer (3) and the aluminum foil layer (1) together to form the yin-yang packaging bag.

2. The antistatic high-barrier yin-yang packaging bag for medicinal powder and the preparation method thereof according to claim 1, wherein the pressure in the reaction kettle is controlled at 2-3 MPa, and the heating temperature of the reaction kettle is 120-130 ℃.

3. The antistatic high-barrier yin-yang packaging bag for medicinal powder and the preparation method thereof according to claim 1, wherein the temperature for grinding the powder is not higher than 80 ℃, and the fineness index of the powder is 60-80 μm.

4. The antistatic high-barrier yin-yang packaging bag of medicinal powder and the preparation method thereof according to claim 1, wherein the additive is a mixture of a fatty acid amino compound and hydroquinone in a ratio of 6:4, and the plasticizer is epoxidized soybean oil.

5. The antistatic high-barrier yin-yang packaging bag for medicinal powder and the preparation method thereof according to claim 1, wherein the antistatic agent I is a mixture of alkenyl sulfonate and alkylamine polyethylene derivative according to a ratio of 7:3, and the antistatic agent II is a polythiophene conductive polymer.

6. The antistatic high-barrier yin-yang packaging bag for medicinal powder and the preparation method thereof according to claim 1, wherein the aluminum foil layer (1) and the transparent layer (3) are fixedly connected by a double-layer hot-melt welding method.

Technical Field

The invention relates to the technical field of packaging bag production, in particular to an antistatic high-barrier yin-yang packaging bag of medicinal powder and a preparation method thereof.

Background

When the film is used for packaging medicinal powder, the sealing strength is reduced greatly due to the electrostatic attraction of the heat sealing surface, so that the medicinal powder fails due to damage in the processes of storage and transportation, and the transparency of the packaging bag is reduced due to electrostatic dust absorption of the medicinal powder packaged in the transparent packaging bag, thereby causing poor visual effect.

Chinese patent disclosesAntistatic reinforced PP plastic and preparation method thereof(Notification No. 2CN105504492A) According to the patent technology, through reasonable proportioning, the types and the using amounts of inorganic fillers and antistatic agents suitable for improving the mechanical property of PP are preferably selected, the antistatic property and the strength are improved, but the barrier effect is poor, and the package in the bag is easy to damp and lose efficacy. Therefore, the person skilled in the art provides an antistatic high-barrier yin-yang packaging bag for medicinal powder and a preparation method thereof, so as to solve the problems in the background art.

Disclosure of Invention

The invention aims to provide an antistatic high-barrier yin-yang packaging bag of medicinal powder and a preparation method thereof, so as to solve the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme:

the utility model provides an antistatic high resistant negative and positive wrapping bag of separation of medicinal powder and preparation method thereof, includes the aluminium foil layer and welds the stratum lucidum in aluminium foil layer upper end through the hot melt mode, the inboard of handing-over department of aluminium foil layer and stratum lucidum is provided with the self-supporting zip fastener, and the one end of aluminium foil layer and stratum lucidum is close to the front end of self-supporting zip fastener and has seted up the hand and tear the mouth, and its preparation method includes following step:

s1, mixing ethylene and vinyl acetate according to a ratio of 25:75, taking methanol as a solvent, and carrying out free radical copolymerization on the vinyl acetate and the ethylene as monomers in a reaction kettle to obtain an ethylene-vinyl acetate copolymer;

s2, adding methanol, sodium hydroxide and the ethylene-vinyl acetate copolymer into a reaction kettle according to the ratio of 55:8:37, filling nitrogen into the reaction kettle to discharge oxygen in the reaction kettle, then, starting a vacuum pump to pump the reaction kettle to form negative pressure, heating and stirring the reaction kettle, properly supplementing the methanol in the heating process, continuously pumping the vacuum pump to ensure that the negative pressure in the reaction kettle is not changed, discharging methanol steam and byproducts through the vacuum pump, and carrying out alcoholysis on acetyl in the ethylene-vinyl acetate copolymer to form hydroxyl so as to obtain the ethylene-vinyl alcohol copolymer;

s3, filtering, cleaning and drying the ethylene-vinyl alcohol copolymer obtained in the step S2, adding an additive, a plasticizer, an antistatic agent I and ethylene-vinyl alcohol into the copolymer according to the proportion of 3:14:5:78, mixing, and grinding into powder;

s4, putting the powder obtained in the step S3 into an internal mixer for plastication and mixing to form plastic slices, processing the plastic slices into plastic particles through a double-screw extruder, and processing the plastic particles into a plastic film through a film blowing machine;

s5, spraying the antistatic agent II on the plastic film obtained in the step S4 through a film plating machine, and cutting the plastic film into a set shape to form a transparent layer;

s6, cutting the aluminum foil roll into the size same as that of the transparent layer, spraying conductive ink on the surface to form an aluminum foil layer, respectively adhering the self-standing zipper on the aluminum foil layer and the transparent layer, and welding the transparent layer and the aluminum foil layer together to form the yin-yang packaging bag.

As a still further scheme of the invention: the pressure in the reaction kettle is controlled to be 2-3 MPa, and the heating temperature of the reaction kettle is 120-130 ℃.

As a still further scheme of the invention: the grinding temperature of the powder is not higher than 80 ℃, and the fineness index of the powder is 60-80 mu m.

As a still further scheme of the invention: the additive is a mixture of a fatty acid amino compound and hydroquinone in a ratio of 6:4, and the plasticizer is epoxidized soybean oil.

As a still further scheme of the invention: the antistatic agent I is a mixture of alkenyl sulfonate and alkylamine polyethylene derivatives according to a ratio of 7:3, and the antistatic agent II is a polythiophene conductive polymer.

As a still further scheme of the invention: the aluminum foil layer and the transparent layer are fixedly connected in a double-layer hot melting welding mode.

Compared with the prior art, the invention has the beneficial effects that:

vinyl acetate and ethylene are copolymerized to obtain ethylene-vinyl acetate copolymer, acetyl in the ethylene-vinyl acetate copolymer is alcoholyzed to obtain hydroxyl to obtain ethylene-vinyl alcohol copolymer with high barrier property, has blocking effect on gas, smell, solvent and the like, prevents external oxygen and moisture from entering the yin-yang packaging bag, improves the safety of medicinal powder, by adding an antistatic agent I into an ethylene-vinyl alcohol copolymer and spraying an antistatic agent II on the surface of the prepared plastic film, thereby greatly improving the antistatic effect of the transparent layer, ensuring that the surface resistivity of the aluminum foil layer is stable and the aluminum foil layer has good antistatic performance by spraying conductive ink on the surface of the aluminum foil layer, and the antistatic effect of the whole yin-yang packaging bag is further improved, so that the whole yin-yang packaging bag has antistatic and gas barrier properties.

Drawings

Fig. 1 is a structural schematic diagram of an antistatic high-barrier yin-yang packaging bag of medicinal powder and a preparation method thereof.

In the figure: 1. an aluminum foil layer; 2. a self-standing zipper; 3. a transparent layer; 4. tearing the mouth by hand.

Detailed Description

Referring to fig. 1, in an embodiment of the present invention, an antistatic high-barrier yin-yang packaging bag for pharmaceutical powder and a preparation method thereof include an aluminum foil layer 1 and a transparent layer 3 welded on an upper end of the aluminum foil layer 1 in a hot melting manner, a self-supporting zipper 2 is disposed on an inner side of a joint of the aluminum foil layer 1 and the transparent layer 3, and a hand tearing opening 4 is disposed at a front end of one end of the aluminum foil layer 1 and the transparent layer 3 close to the self-supporting zipper 2, and the preparation method includes the following steps:

s1, mixing ethylene and vinyl acetate according to a ratio of 25:75, taking methanol as a solvent, and carrying out free radical copolymerization on the vinyl acetate and the ethylene as monomers in a reaction kettle to obtain an ethylene-vinyl acetate copolymer;

s2, adding methanol, sodium hydroxide and the ethylene-vinyl acetate copolymer into a reaction kettle according to the ratio of 55:8:37, filling nitrogen into the reaction kettle to discharge oxygen in the reaction kettle, then, starting a vacuum pump to pump the reaction kettle to form negative pressure, heating and stirring the reaction kettle, properly supplementing the methanol in the heating process, continuously pumping the vacuum pump to ensure that the negative pressure in the reaction kettle is not changed, discharging methanol steam and byproducts through the vacuum pump, and carrying out alcoholysis on acetyl in the ethylene-vinyl acetate copolymer to form hydroxyl so as to obtain the ethylene-vinyl alcohol copolymer;

s3, filtering, cleaning and drying the ethylene-vinyl alcohol copolymer obtained in the step S2, adding an additive, a plasticizer, an antistatic agent I and ethylene-vinyl alcohol into the copolymer according to the proportion of 3:14:5:78, mixing, and grinding into powder;

s4, putting the powder obtained in the step S3 into an internal mixer for plastication and mixing to form plastic slices, processing the plastic slices into plastic particles through a double-screw extruder, and processing the plastic particles into a plastic film through a film blowing machine;

s5, spraying the antistatic agent II on the plastic film obtained in the step S4 through a film plating machine, and cutting the plastic film into a set shape to form a transparent layer 3;

s6, cutting the aluminum foil roll into the size same as that of the transparent layer, spraying conductive ink on the surface to form an aluminum foil layer 1, respectively adhering the self-standing zipper 2 on the aluminum foil layer 1 and the transparent layer 3, and welding the transparent layer 3 and the aluminum foil layer 1 together to form the yin-yang packaging bag.

Preferentially, the pressure in the reaction kettle is controlled to be 2-3 MPa, and the heating temperature of the reaction kettle is 120-130 ℃.

Preferably, the temperature for grinding the powder is not higher than 80 ℃, and the fineness index of the powder is 60-80 mu m.

Preferably, the additive is a mixture of a fatty acid amino compound and hydroquinone in a ratio of 6:4, and the plasticizer is epoxidized soybean oil.

Preferably, the antistatic agent I is a mixture of alkenyl sulfonate and alkylamine polyethylene derivative according to a ratio of 7:3, and the antistatic agent II is a polythiophene conductive polymer.

Preferably, the aluminum foil layer 1 and the transparent layer 3 are fixedly connected by means of double-layer hot-melt welding.

First, the barrier properties (including air permeability and moisture permeability) of comparative examples and examples were examined

Comparative example: common PVDC films, nylon films, polyester films, PVC films and PP films on the market;

first, a PVDC film, a nylon film, a polyester film, a PVC film, and a PP film, all of which have the same thickness as that of the transparent layer in the examples and a thickness of 0.015 mm, were randomly purchased from the market, and the films were cut into small squares of 100 × 100cm, wherein 20 pieces of each film were taken;

the air permeability of each film was measured under the environment of 5 ℃, 10 ℃, 15 ℃, 20 ℃, 25 ℃, 30 ℃ and 35 ℃ respectively, and the unit of air permeability: cm3/(m2 d); the moisture permeability (the amount of water vapor permeating per unit surface area in unit time) of each film was measured at a temperature (40 ± 1) ° c and a relative humidity of 90% ± 2%, the unit of moisture permeability: gm/m2 d, and then the average air permeability and the average moisture permeability of each film were calculated.

The experimental data reported are as follows:

table 1: average air permeability and average moisture permeability analysis results of examples and comparative examples:

as can be analyzed from Table 1, the air permeabilities of the films of examples in the environments of 5 ℃, 10 ℃, 15 ℃, 20 ℃, 25 ℃, 30 ℃ and 35 ℃ were much smaller than those of the PVDC films, nylon films, polyester films, PVC films and PP films of comparative examples; the film of the example has a moisture permeability lower than that of the nylon film, the nylon film and the PVC film of the comparative example and a moisture permeability slightly higher than that of the PVDC film and the PP film of the comparative example in an environment of a temperature (40 ± 1) ° c and a relative humidity of 90% ± 2%, and further, as can be seen from a comprehensive comparison of the air permeability and the moisture permeability: the barrier properties of the films of examples were superior to those of the PVDC, nylon, polyester, PVC and PP films of the comparative examples.

Second, antistatic Properties (resistivity) of comparative examples and examples were measured

Comparative example: common polyethylene films, polytetrafluoroethylene films, chloroprene rubber films, epoxy resin films and polyester films on the market;

first, a polyethylene film, a polytetrafluoroethylene film, a chloroprene rubber film, an epoxy resin film and a polyester film were randomly purchased from the market, and the thicknesses thereof were the same as those of the transparent layers in the examples, and were all 0.015 mm, and the films were cut into small squares of 100 × 100cm, wherein 20 pieces of each film were taken;

under the same environment, detecting the surface resistivity and the volume resistivity of each film by a tester, and calculating the average surface resistivity and the average volume resistivity of each film, wherein the unit of the resistivity is as follows: omega.m.

The experimental data reported are as follows:

table 2: results of surface resistivity and volume resistivity analysis of examples and comparative examples:

from table 2, it can be analyzed that the surface resistivity and the volume resistivity of the example film are smaller than those of the polyethylene film, the polytetrafluoroethylene film, the chloroprene rubber film, the epoxy resin film and the polyester film in the comparative example, and further, it can be found that the antistatic property of the example film is superior to that of the polyethylene film, the polytetrafluoroethylene film, the chloroprene rubber film, the epoxy resin film and the polyester film in the comparative example.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention are equivalent to or changed within the technical scope of the present invention.