阅读说明：本技术 一种农药组合物及其制备方法和应用 (Pesticide composition and preparation method and application thereof ) 是由 沈建良 凌江涛 钱海宾 丁菲 盛莹盈 于 2020-06-29 设计创作，主要内容包括：本发明公开了一种农药组合物及其制备方法和应用,涉及农药复配技术领域。本发明所述的农药组合物含有有效成分甲维盐和丙硫菌唑,该农药组合物能够同时杀菌杀虫,解决农业生产中遇到的作物中后期施药困难、后期用药效果不明显、反复用药的问题。能够很好的防治作物生长期,尤其是中后期的病虫害,且能够降低农药施用时的人工成本和用药成本,具有经济、高效、环保的特点。(The invention discloses a pesticide composition and a preparation method and application thereof, and relates to the technical field of pesticide compounding. The pesticide composition contains the effective components of emamectin benzoate and prothioconazole, can kill bacteria and kill insects simultaneously, and solves the problems of difficult pesticide application in the middle and later periods of crops, unobvious later-period pesticide application effect and repeated pesticide application in agricultural production. Can well prevent and treat plant diseases and insect pests in the crop growth period, particularly in the middle and later periods, can reduce the labor cost and the pesticide cost when the pesticide is applied, and has the characteristics of economy, high efficiency and environmental protection.)

1. A pesticidal composition characterized by: the pesticide composition comprises an effective component of emamectin benzoate and an effective component of prothioconazole; the total mass of the pesticide composition is 100%, wherein the sum of the mass fractions of the emamectin benzoate serving as the active ingredient and the prothioconazole serving as the active ingredient is 6-30%; the weight ratio of the emamectin benzoate as the effective component to the prothioconazole as the effective component is 1: 0.05-80.

2. The pesticidal composition according to claim 1, characterized in that: the total mass of the pesticide composition is 100%, wherein the sum of the mass fractions of the emamectin benzoate serving as the effective component and the prothioconazole serving as the effective component is 6-24%.

3. The pesticidal composition according to claim 2, characterized in that: the total mass of the pesticide composition is 100%, wherein the sum of the mass fractions of the emamectin benzoate serving as the effective component and the prothioconazole serving as the effective component is 18-24%.

4. The pesticidal composition according to claim 1, characterized in that: the weight ratio of the emamectin benzoate serving as the effective component to the prothioconazole serving as the effective component is 1: 1-10.

5. The pesticidal composition according to claim 4, characterized in that: the weight ratio of the emamectin benzoate as the effective component to the prothioconazole as the effective component is 1: 4-6.

6. The pesticidal composition according to claim 1, characterized in that: the pesticide composition is in the form of any one of a suspending agent, a water dispersible granule, a wettable powder, an emulsifiable concentrate or an emulsifiable granule.

7. The pesticidal composition according to claim 1 or 6, characterized in that: the pesticide composition also comprises one or more of an auxiliary agent, a filler or a solvent; the auxiliary agent comprises one or more of a dispersing agent, an antifreezing agent, a thickening agent, a defoaming agent, a wetting agent, a disintegrating agent and an emulsifying agent.

8. The pesticidal composition according to claim 7, characterized in that:

the emulsifier comprises one or a mixture of more of calcium dodecyl benzene sulfonate, styryl phenol polyoxyethylene ether, castor oil polyoxyethylene ether, polyoxyethylene fatty alcohol ether and fatty alcohol polyoxyethylene ester;

the dispersing agent comprises one or a mixture of more of lignosulfonate, alkylphenol polyoxyethylene ether sulfate, 2-naphthalenesulfonic acid formaldehyde polymer sodium salt, fatty acid ester sulfate and polyoxyethylene polyoxypropylene segmented copolymer;

the wetting agent comprises one or a mixture of more of fatty amide N-methyl taurinic acid sodium salt, petroleum sodium sulfonate, tea seed cake powder and saponin powder;

the thickening agent comprises one or a mixture of more of xanthan gum, bentonite, magnesium aluminum silicate and white carbon black;

the antifreezing agent comprises one or a mixture of more of ethylene glycol, glycerol, propylene glycol and polyethylene glycol;

the defoaming agent comprises one or a mixture of more of organic silicone oil, methanol, ethanol and epoxidized soybean oil;

the disintegrating agent comprises one or a mixture of more of urea, magnesium chloride, sodium chloride and ammonium sulfate;

the filler comprises one or a mixture of more of kaolin, diatomite, white carbon black, light calcium carbonate and talcum powder;

the solvent comprises one or a mixture of more of ethanol, cyclohexanone, 150# solvent oil, methyl pyrrolidone, octyl pyrrolidone, dimethylformamide, dimethyl sulfoxide and decanamide.

9. The pesticidal composition according to claim 6, characterized in that: the raw material formula of the emulsifiable granules comprises the following components by the total mass of 100 percent:

10. a preparation method of a pesticide composition is characterized by comprising the following steps: when the pesticidal composition according to any one of claims 1 to 9 is formulated into any one of a suspension concentrate, a water dispersible granule, a wettable powder, an emulsifiable concentrate or an emulsifiable granule, the production steps comprise: the components of the pesticide composition are mixed and then stirred, and finally the preparation is obtained.

11. The method for producing a pesticidal composition according to claim 10, characterized in that: when the emulsifiable granules are prepared, the specific production steps comprise:

(1) uniformly mixing the prothioconazole, the emamectin benzoate and the emulsifier, adding a solvent, and mixing to a homogeneous phase;

(2) uniformly mixing the filler and the dispersant, and then carrying out jet milling;

(3) spraying the raw materials treated in the step (1) into the raw materials treated in the step (2), and uniformly mixing by shearing and stirring;

(4) and (4) extruding and granulating the uniformly mixed materials in the step (3) to obtain the emulsifiable granules.

12. Use of a pesticidal composition according to any one of claims 1 to 9 for controlling crop pests.

13. Use of a pesticidal composition according to claim 12 for controlling crop pests, characterized in that: the plant diseases and insect pests comprise lepidoptera, diptera and thrips, and diseases of cereal crops.

Technical Field

The invention relates to the field of pesticides, and particularly relates to a pesticide composition with emamectin benzoate and prothioconazole as effective components, which has the effects of sterilization and disinsection.

Background

The Emamectin Benzoate (Emamectin Benzoate) methylamino abamectin Benzoate (Emamectin Benzoate) is a novel high-efficiency semi-synthetic antibiotic pesticide synthesized from a fermentation product abamectin B1, and the trade name of the Emamectin Benzoate (Emamectin Benzoate) is Proclaim O (banleptin). The pesticide has the characteristics of ultra-high efficiency, low toxicity (the preparation is nearly nontoxic), no residue, no public nuisance and the like, the insecticidal activity is improved by 1-3 orders of magnitude compared with that of abamectin, the activity to larvae of lepidoptera insects and other pests and mites is extremely high, the pesticide has both stomach toxicity and contact poisoning effects, and has good effect under very low dosage (0.084-2 g/ha), and the pesticide has no harm to beneficial insects in the process of controlling the pests, is beneficial to the comprehensive control of the pests, expands the insecticidal spectrum and reduces the toxicity to people and livestock.

Prothioconazole (prothioconazole) is a novel broad-spectrum triazolethione bactericide developed by Bayer company and is mainly used for preventing and treating a plurality of diseases of cereals, wheat and bean crops and the like, and the action mechanism of prothioconazole is to inhibit the demethylation action on 14-position of lanosterol or 2, 4-methylene dihydro MI, which are precursors of sterol in fungi, namely demethylation inhibitors (DMIs). Not only has good systemic activity, excellent protection, treatment and eradication activity, but also has long lasting period. Through a large number of field efficacy tests, the results show that the prothioconazole has good safety to crops, good effects of preventing and treating diseases and obvious yield increase, and compared with triazole bactericides, the prothioconazole has broad-spectrum bactericidal activity.

The pesticide containing a single active component has poor actual effect and narrow action range, and cannot achieve the aim of killing pests and germs simultaneously. Although prothioconazole, abamectin, emamectin benzoate and the like are all high-efficiency as bactericides and insecticides, when the single agent is used for a long time, diseases and pests are easy to generate drug resistance, so that the problems of increased dosage, reduced control effect and shortened lasting period are caused, and the sustainable development of the environment is not facilitated.

Disclosure of Invention

The invention aims to provide a pesticide composition containing emamectin benzoate and prothioconazole, which can kill bacteria and kill insects simultaneously through the synergistic action of the emamectin benzoate and the prothioconazole.

In order to achieve the purpose, the invention adopts the following technical scheme:

the invention provides a pesticide composition, which comprises an effective component emamectin benzoate and an effective component prothioconazole; the total mass of the pesticide composition is 100%, wherein the sum of the mass fractions of the emamectin benzoate serving as the active ingredient and the prothioconazole serving as the active ingredient is 6-30%; the weight ratio of the emamectin benzoate as the effective component to the prothioconazole as the effective component is 1: 0.05-80.

Preferably, the total mass of the emamectin benzoate and the prothioconazole as the effective components is 6-24% based on 100% of the total mass of the pesticide composition.

More preferably, the total mass fraction of the emamectin benzoate and the prothioconazole as the effective components is 18-24% based on 100% of the total mass of the pesticide composition.

Preferably, the weight ratio of the emamectin benzoate as the effective component to the prothioconazole as the effective component is 1: 1-10.

Further preferably, the weight ratio of the emamectin benzoate as the effective component to the prothioconazole as the effective component is 1: 4-6.

Preferably, the pesticide composition is in the form of any one of a suspending agent, a water dispersible granule, a wettable powder, an emulsifiable concentrate or an emulsifiable granule.

Preferably, the pesticide composition further comprises one or more of an adjuvant, a filler or a solvent.

Further preferably, the auxiliary agent comprises one or more of a dispersing agent, an antifreezing agent, a thickening agent, an antifoaming agent, a wetting agent, a disintegrating agent and an emulsifying agent.

More preferably, the emulsifier comprises one or a mixture of more of calcium dodecylbenzene sulfonate, styrylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, polyoxyethylene fatty alcohol ether and fatty alcohol polyoxyethylene ester.

More preferably, the dispersing agent comprises one or a mixture of more of lignosulfonate, alkylphenol polyoxyethylene ether sulfate, sodium salt of 2-naphthalene sulfonic acid formaldehyde polymer, fatty acid ester sulfate and polyoxyethylene polyoxypropylene block copolymer.

More preferably, the wetting agent comprises one or a mixture of several of fatty amide N-methyl taurinic acid sodium salt, sodium petroleum sulfonate, tea seed cake powder and Chinese honeylocust fruit powder.

More preferably, the thickener comprises one or a mixture of xanthan gum, bentonite, magnesium aluminum silicate and white carbon black.

More preferably, the antifreeze comprises one or a mixture of more of ethylene glycol, glycerol, propylene glycol and polyethylene glycol.

More preferably, the defoaming agent comprises one or a mixture of several of organic silicone oil, methanol, ethanol and epoxidized soybean oil.

More preferably, the disintegrating agent comprises one or a mixture of more of urea, magnesium chloride, sodium chloride and ammonium sulfate.

More preferably, the filler comprises one or a mixture of more of kaolin, diatomite, white carbon black, light calcium carbonate and talcum powder.

More preferably, the solvent comprises one or a mixture of more of ethanol, cyclohexanone, 150# solvent oil, methyl pyrrolidone, octyl pyrrolidone, dimethylformamide, dimethyl sulfoxide and decanamide.

Further preferably, when the composition is in the form of a suspension, the composition may comprise the following components in percentage by weight, based on 100% of the total mass:

further preferably, when the composition is in the form of water dispersible granules, the composition can comprise the following components in percentage by weight, based on 100% of the total mass:

further preferably, when the dosage form of the composition is wettable powder, the composition can comprise the following components in percentage by weight, based on 100% of the total mass:

further preferably, when the composition is in the form of emulsifiable concentrate, the composition can comprise the following components in percentage by weight, based on 100% of the total mass:

further preferably, when the composition is an emulsifiable granule, the composition can comprise the following components in percentage by weight based on 100% of the total mass:

more preferably, the raw material formula of the emulsifiable granule comprises the following components by the total mass of 100 percent:

particularly preferably, the raw material formula of the emulsifiable granule comprises the following components by the total mass of 100 percent:

according to a specific and preferred embodiment, the emulsifier is calcium dodecylbenzene sulfonate and/or styrylphenol polyoxyethylene ether, the solvent is 150# solvent oil, the dispersant and/or wetting agent is 2. naphthalene sulfonic acid formaldehyde polymer sodium salt, and the filler is white carbon black and/or diatomite.

Further preferably, the mass ratio of the calcium dodecylbenzene sulfonate to the styrylphenol polyoxyethylene ether is 1: 1-4, more preferably 1: 2-3.5, and particularly preferably 1: 2.5-3.3.

In another aspect, the invention provides a preparation method of the pesticide composition.

Preferably, the pesticide composition is prepared into any one of a suspending agent, a water dispersible granule, a wettable powder, an emulsifiable concentrate or an emulsifiable granule, and the production steps comprise mixing the components of the pesticide composition, stirring and finally obtaining the dosage form.

Further preferably, the pesticide composition is prepared into emulsifiable granules, and the specific production steps comprise:

(1) uniformly mixing the prothioconazole, the emamectin benzoate and the emulsifier, adding a solvent, and mixing to a homogeneous phase;

(2) uniformly mixing the filler and the dispersant, and then carrying out jet milling;

(3) spraying the raw materials treated in the step (1) into the raw materials treated in the step (2), and uniformly mixing by shearing and stirring;

(4) and (4) extruding and granulating the uniformly mixed materials in the step (3) to obtain the emulsifiable granules.

Further preferably, the pesticide composition is prepared into a suspending agent, and the specific production steps comprise: adding purified water, a dispersing agent, a thickening agent, a emamectin benzoate technical and a prothioconazole technical into a shearing kettle, selectively adding an antifreezing agent and a defoaming agent, adding the mixed crude suspension into a sand mill at a constant speed, and grinding until the particle size is qualified to obtain a qualified finished product.

Further preferably, the pesticide composition is prepared into water dispersible granules, and the specific production steps comprise: the weighed auxiliary agent, the filler and the original drug are uniformly mixed, the powder machine carries out air flow crushing, then the material is transferred to the kneading machine for kneading, and then the water dispersible granule of the composition can be prepared after granulation, drying and screening and sampling analysis.

Further preferably, the pesticide composition is prepared into wettable powder, and the specific production steps comprise: mixing the raw pesticide, the dispersing agent, the wetting agent and the filler according to the formula proportion, selectively adding the defoaming agent, uniformly stirring in a stirring kettle, crushing by a jet mill, and uniformly mixing to prepare the wettable powder of the composition.

Further preferably, the pesticide composition is prepared into emulsifiable concentrate, and the specific production steps comprise: the emamectin benzoate and the prothioconazole are added into the solvent to be completely dissolved, then the emulsifier is added and stirred uniformly to form transparent oily liquid, and the transparent oily liquid is filled to prepare the missible oil preparation of the composition.

The invention also provides application of the pesticide composition in prevention and treatment of crop diseases and insect pests.

Specifically, the pests and diseases comprise lepidoptera, diptera and thrips, and diseases of cereal crops.

More specifically, the pests include lepidoptera, diptera and thrips, including but not limited to, pleomorphus littoralis, tobacco aphid, cotton bollworm, tobacco hornworm, diamondback moth armyworm, beet armyworm, plutella xylostella, cabbage looper, cabbage pink butterfly, cabbage borer, cabbage striped rice borer, tomato hornworm, potato beetle, and black ladybug.

More specifically, the diseases of cereal crops include, but are not limited to, powdery mildew, banded sclerotial blight, fusarium wilt, leaf spot, rust disease, sclerotinia, net blotch, leaf blotch, sclerotinia, gray mold, black spot, brown spot, black shank, sclerotinia, rust disease and the like.

On the one hand, the emamectin benzoate has incomparable activity to other pesticides on a plurality of pests, and particularly has ultrahigh effect on lepidoptera, diptera and thrips, such as cabbage loopers, tobacco aphid moths, cotton bollworms, tobacco hornworms, diamond back moth armyworms, beet armyworms, plutella xylostella, cabbage loopers, cabbage borers, cabbage striped rice borers, tomato hornworms, potato beetles, cryptotya japonica and the like. On the other hand, prothioconazole is mainly used for controlling a plurality of diseases of cereal crops such as wheat, barley, rape, peanut, rice, bean crops and the like. Has good control effect on almost all wheat diseases, such as powdery mildew, banded sclerotial blight, leaf spot, rust disease, sclerotinia, net blotch, leaf spot and the like of wheat and barley. Can also prevent and control soil-borne diseases of the rape and the peanut, such as sclerotinia, and main leaf surface diseases, such as gray mold, black spot, brown spot, black shank, sclerotinia, rust and the like.

Due to the adoption of the technical scheme, compared with the prior art, the invention has the following advantages:

1. the prevention and control objects are enlarged, and the sterilization and disinsection effects are achieved;

2. the pesticide has better convenience, saves the medicine and the labor, and can reduce the times of pesticide application by mixing the pesticide and the bactericide for use, thereby reducing the labor cost;

3. the fertilizer is suitable for various crops and various insect pests and crop diseases;

4. the drug effect is improved, and compared with a single agent, the compound has obvious synergistic effect and improves the control effect;

5. the dosage is reduced by mixing the medicament, so that the cost is reduced and the pollution to the environment is reduced;

6. the pesticide composition can be prepared into various dosage forms, is not limited to one preparation, and meets various market requirements.

Compared with the prior art, the pesticide composition has reasonable components, good effect of preventing and treating crop diseases and insect pests, low dosage and cost, and obvious synergistic effect instead of simple superposition of the components in insecticidal and bactericidal activity effect.

Detailed Description

The present invention will be described in further detail with reference to specific examples. It is to be understood that these embodiments are provided to illustrate the basic principles, essential features and advantages of the present invention, and the present invention is not limited by the following embodiments. The implementation conditions used in the examples can be further adjusted according to specific requirements, and the implementation conditions not indicated are generally the conditions in routine experiments. The contents are all mass contents.

The embodiment of the invention prepares the active ingredients of the pesticide into the emulsifiable granules with different mass contents, and is developed aiming at different control effects and control objects thereof. The pesticide preparations with different mass contents mainly embody: the processing mode, the environmental protection, the safety and the drug effect can be known only through a large number of tests, and the quality proportion has the advantages.