阅读说明：本技术 一种可自检气密性并准确提取的移液装置及方法 (Pipetting device and method capable of self-checking air tightness and accurately extracting ) 是由 毕利军 马文美 杨晓 马道稳 于 2020-05-14 设计创作，主要内容包括：本发明涉及一种可自检气密性并准确提取的移液装置,包括如下部件：机架,所述机架包括底座、上支撑板、侧支撑板和侧支架,所述侧支撑板的两端分别与所述底座和所述上支撑板连接,所述侧支架设置在所述侧支撑板上；抽吸机构,设置在所述侧支架上,用于抽吸样品；升降机构,设置在所述上支撑板上,其包括第二滑块,可沿所述侧支撑板的高度方向上升或下降；移液机构,设置在所述第二滑块上用于移取样品。本发明装置结构简单,体积小,能够满足生物医疗器械领域对小而精的移液装置需求。(The invention relates to a liquid transfer device capable of self-checking air tightness and accurately extracting, which comprises the following components: the rack comprises a base, an upper supporting plate, a side supporting plate and a side support, wherein two ends of the side supporting plate are respectively connected with the base and the upper supporting plate, and the side support is arranged on the side supporting plate; the suction mechanism is arranged on the side bracket and is used for sucking a sample; the lifting mechanism is arranged on the upper supporting plate and comprises a second sliding block which can ascend or descend along the height direction of the side supporting plate; and the liquid transferring mechanism is arranged on the second sliding block and used for transferring and taking the sample. The device has simple structure and small volume, and can meet the requirements of the field of biomedical equipment on small and precise liquid transfer devices.)

1. A liquid transfer device capable of self-checking air tightness and accurately extracting is characterized by comprising the following components:

the rack (1) comprises a base (101), an upper supporting plate (102), a side supporting plate (103) and a side support (104), wherein two ends of the side supporting plate (103) are respectively connected with the base (101) and the upper supporting plate (102), and the side support (104) is arranged on the side supporting plate (103);

a suction mechanism provided on the side stand (104) for sucking a sample in a sample container;

the lifting mechanism is arranged on the upper supporting plate (102), comprises a second sliding block (10) and can ascend or descend along the height direction of the side supporting plate (103);

and the liquid transfer mechanism is arranged on the second slide block (10) and is used for transferring the sample in the sample container.

2. Pipetting device according to claim 1,

the suction mechanism comprises a liquid transfer pump (6), the liquid transfer pump (6) comprises a liquid transfer motor (601), a lifting shaft screw (604) and a suction barrel (602), the output end of the liquid transfer motor (601) is connected with the lifting shaft screw (604), the lifting shaft screw (604) is connected with the lower end of the suction barrel (602), and a piston (603) is arranged in the suction barrel (602).

3. The pipetting device according to claim 1, characterized in that the lifting mechanism comprises a lifting motor (3) and a pipetting screw (4), the lifting motor (3) is arranged on the upper end surface of the upper support plate (102), the output end of the lifting motor (3) is connected with the pipetting screw (4), the pipetting screw (4) is sleeved with the second slide block (10) which can slide along the axial direction of the pipetting motor, and the second slide block (10) is positioned below the lower end surface of the upper support plate (102).

4. Pipetting device according to claim 2, characterized in that the pipetting mechanism comprises a catheter (5), a three-way valve (11) and a first slide (9), the lower end of the first slide (9) being provided with a grip (901), the upper end of the first slide (9) being fixed to the second slide (10) and being connected to the first end of the catheter (5), the second end of the catheter (5) being connected to an air inlet of the three-way valve (11), the first and second air outlets of the three-way valve (11) being connected to the pressure sensor (7) and the upper end of the aspiration barrel (602), respectively.

5. The pipette device according to any one of claims 1 to 4, wherein the base (101) and the upper support plate (102) are located on a left end surface of the side support plate (103), and the side holder (104) is located on a right end surface of the side support plate (103).

6. Pipetting device according to any one of claims 1 to 4, characterized by further comprising a controller (8), the controller (8) being provided at the side stand (104) for controlling the pressure sensor (7).

7. Pipetting device according to claim 4, characterized in that the holder (901) is cylindrical and that its lower end cooperates with the tip (2).

8. Pipetting device according to claim 7, characterized in that the gripping section (901) is arranged vertically parallel to the pipetting screw (4).

9. A method of operating a pipetting device as recited in any one of claims 1 to 8 comprising the steps of:

(1) when a sample is sucked, the lifting motor (3) is started, the liquid-transferring mechanism is driven by the lifting motor (3) to move downwards to a designated position above a sample tube, then the liquid-transferring motor (601) is started, the piston (603) moves downwards to generate suction force, the gun head (2) sucks the sample under the action of the suction force, and the amount of the sucked sample is obtained by monitoring the pressure change of the pressure sensor (7) in the process of sucking the sample and after the sample is taken;

(2) when the sample is discharged, the piston (603) moves upwards to generate thrust, and the pipetting mechanism discharges the sample in the gun head (2) under the action of the thrust.

Technical Field

The invention relates to a liquid transfer device and a method capable of self-checking air tightness and accurately extracting, belonging to the technical field of biomedical equipment.

Background

The air tightness of the existing liquid transferring system of medical equipment is ensured by real-time and regular inspection of an installation process and manual naked eyes, but if pipeline leakage occurs in the working process, the poor air tightness cannot be accurately detected, and certain pollution consequences can be caused when a sample with biological pollution is extracted; in addition, when the sample needs to be processed proportionally, the liquid amount for extracting the sample cannot be accurately measured due to the existing pipetting system.

Disclosure of Invention

Aiming at the outstanding problems, the invention provides a liquid transfer device and a method capable of self-checking air tightness and accurately extracting.

In order to achieve the purpose, the invention adopts the following technical scheme:

a pipetting device capable of self-checking air tightness and accurately extracting comprises the following components:

the device comprises a machine frame 1, wherein the machine frame 1 comprises a base 101, an upper supporting plate 102, a side supporting plate 103 and a side support 104, two ends of the side supporting plate 103 are respectively connected with the base 101 and the upper supporting plate 102, and the side support 104 is arranged on the side supporting plate 103;

a suction mechanism provided on the side stand 104 for sucking the sample in the sample container;

a lifting mechanism which is arranged on the upper supporting plate 102, comprises a second slide block 10 and can be lifted or lowered along the height direction of the side supporting plate 103;

and the liquid transferring mechanism is arranged on the second slide block 10 and is used for transferring the sample in the sample container.

The pipetting device, preferably, the aspiration mechanism includes a pipetting pump 6, the pipetting pump 6 includes a pipetting motor 601, a lifting shaft screw 604 and an aspiration cylinder 602, an output end of the pipetting motor 601 is connected with the lifting shaft screw 604, the lifting shaft screw 604 is connected with a lower end of the aspiration cylinder 602, and a piston 603 is disposed in the aspiration cylinder 602.

The liquid-transfering device, preferably, elevating system includes elevator motor 3 and moves liquid screw rod 4, elevator motor 3 sets up on the up end of last backup pad 102, elevator motor 3's output with move liquid screw rod 4 and be connected, move liquid screw rod 4 and go up the fit on the ring and have and follow its axial slip second slider 10, second slider 10 is located go up the below of backup pad 102 lower extreme face.

The pipetting device preferably comprises a catheter 5, a three-way valve 11 and a first slide block 9, wherein the lower end of the first slide block 9 is provided with a clamping part 901, the upper end of the first slide block 9 is fixed on the second slide block 10 and is connected with the first end of the catheter 5, the second end of the catheter 5 is connected with an air inlet of the three-way valve 11, and a first air outlet and a second air outlet of the three-way valve 11 are respectively connected with a pressure sensor 7 and the upper end of the suction cylinder 602.

The pipetting device, preferably, the base 101 and the upper support plate 102 are located on the left end surface of the side support plate 103, and the side support 104 is located on the right end surface of the side support plate 103.

The pipetting device preferably further comprises a controller 8, wherein the controller 8 is arranged on the side bracket (104) and is used for controlling the pressure sensor 7.

In the pipetting device, the clamping part 901 is preferably a cylinder, and the lower end of the clamping part is matched with the gun head 2.

The pipetting device is preferably arranged such that the holding section 901 is vertically parallel to the pipetting screw 4.

Due to the adoption of the technical scheme, the invention has the following advantages:

1. the device can monitor the pressure in the liquid transferring process in real time by additionally arranging the pressure sensor, so that whether the tightness of the device is intact or not is judged, and the defect that whether the air tightness of the device is good or not can be judged only by naked eyes in the prior art is overcome;

2. according to the invention, the pressure sensor is additionally arranged, the pressure data is converted into data capable of reflecting the liquid absorption amount, and the data is monitored by the controller, so that the airtightness of the device can be judged, and the amount of a sample can be accurately measured;

3. the device has simple structure and small volume, and can meet the requirements of the field of biomedical equipment on small and precise liquid transfer devices.

Drawings

FIG. 1 is a schematic view of the overall structure of the apparatus of the present invention;

the respective symbols in the figure are as follows:

1-a frame, 101-a base, 102-an upper supporting plate, 103-a side supporting plate and 104-a side bracket; 2-gun head; 3-a lifting motor; 4-a pipetting screw; 5-a catheter; 6-liquid transferring pump, 601-liquid transferring motor, 602-suction cylinder, 603-piston, 604-lifting shaft screw; 7-a pressure sensor; 8-a controller; 9-first slider, 901-clamping part; 10-a second slide block and 11-a three-way valve.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention are described clearly and completely below, and it is obvious that the described embodiments are some, not all embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.