阅读说明：本技术 由旋转平台实现的多种重金属的定性分析和定量分析装置 (Qualitative analysis and quantitative analysis device for multiple heavy metals realized by rotary platform ) 是由 朴炳贤 金炳贤 韩秀妍 李京真 于 2019-08-19 设计创作，主要内容包括：本发明涉及一种重金属的定性分析和定量分析装置,更具体地,涉及一种由旋转平台实现的重金属的定性分析和定量分析装置。(The present invention relates to a qualitative and quantitative analysis apparatus for heavy metals, and more particularly, to a qualitative and quantitative analysis apparatus for heavy metals implemented by a rotary platform.)

1. A rotary platform apparatus for qualitative and quantitative analysis, comprising:

a main injection part located near a rotation axis of the rotation platform and through which a fluid sample containing a heavy metal is injected;

a pH adjusting part for adjusting pH of the injected sample;

a detection part coated with a chelating agent capable of undergoing a color reaction with a heavy metal in the sample by diffusing the sample after pH adjustment; and

a scale for measuring a diffusion distance of the color reaction,

wherein the sample moves from the main injection part to the detection part through the pH adjustment part by controlling the rotation of the device, and

wherein the quantitative analysis is achieved by the color reaction of the heavy metal in the detection section, and the qualitative analysis is achieved by determining the diffusion distance of the color reaction.

2. The rotary stage apparatus for qualitative and quantitative analysis according to claim 1, wherein the pH adjusting part is filled with microbeads, and the surfaces of the microbeads are coated with salt, so that the sample injected into the channel can be adjusted to have a desired pH.

3. The rotary platform device for qualitative and quantitative analysis according to claim 1, further comprising a storage region connecting the pH adjusting part and the sensing part, wherein one end of the sensing part is received in the storage region.

4. The rotary stage apparatus for qualitative and quantitative analysis according to claim 1, wherein the pH adjusting part, the detecting part, and the scale are provided in plurality, and each of the pH adjusting part, the detecting part, and the scale is radially symmetrically provided on the rotary stage.

5. The rotary platform device for qualitative and quantitative analysis according to claim 4, further comprising:

a main channel part connected with one end of the main injection part; and

a plurality of sample distribution channels connected to the main channel part,

wherein each of the sample distribution channels has a shape extending radially symmetrically from the main channel portion.

6. The rotary platform device for qualitative and quantitative analysis according to claim 5, wherein the main injection part comprises a sample reservoir for storing the injected sample before being dispensed to each of the sample dispensing channels, and the sample reservoir and the main channel part are coupled in a spiral shape.

7. The rotary platform device for qualitative and quantitative analysis according to claim 6, further comprising a plurality of on/off valves, wherein,

each of the on/off valves is provided between each of the sample distribution channels and each of the pH adjustment sections, and

the opening/closing valve is opened by a rotational force of the rotation platform to allow the sample received in the sample distribution channel to pass through the pH adjustment part.

8. The rotary platform device for qualitative and quantitative analysis according to claim 7, further comprising a plurality of air circulation channels, wherein,

each of the air flow passages connects each of the storage regions with the other end of one of the detecting portions, and

the air circulation channel increases the evaporation rate of the fluid sample in the detection part and prevents moisture from condensing in the detection part.

9. The rotary platform device for qualitative and quantitative analysis according to claim 8, wherein the rotary platform comprises:

a top layer including the main injection part, the main channel part, the sample distribution channel, the on/off valve, the pH adjustment part, and the storage region;

an intermediate layer including the air circulation channel and the storage region and having a partially open shape corresponding to the detection part; and

a bottom layer including the storage region and the scale and having a space into which the detection part is inserted.

10. The rotary stage apparatus for qualitative and quantitative analysis according to claim 1, wherein the sample is adjusted to have a pH most suitable for reacting the heavy metal contained in the sample with the chelating agent while passing through the microbeads filled in the pH adjustment part.

11. The rotary platform device for qualitative and quantitative analysis according to claim 1, wherein the heavy metal contained in the sample is Fe²⁺、Ni²⁺、Cu²⁺、Cr⁶⁺、Hg²⁺、As²⁺、Zn²⁺、Mn²⁺、Cd²⁺、Pb²⁺、Co²⁺Or Ag⁺。

12. The rotary platform device for qualitative and quantitative analysis according to claim 1, wherein the chelating agent pre-applied on the detection part comprises bathophenanthroline (Bphen), Dimethylglyoxime (DMG), Dithiooxamide (DTO), Diphenylcarbazide (DPC), Dithizone (DTZ), chrome black t (ebt), or 1- (2-pyridylazo) -2-naphthol (PAN).

13. The rotary platform device for qualitative and quantitative analysis according to claim 6, wherein the rotation of the device is controlled by:

rotating the device for a first time and then stopping the rotation to move the sample injected into the main injection part to the sample distribution channel,

rotating the device a second time to move the sample moved to the sample distribution channel to the storage region through the pH adjustment portion; and is

Stopping rotation of the device to diffuse the sample moved to the storage area into the detection portion.

14. The rotary platform device for qualitative and quantitative analysis according to claim 10, wherein the first and second rotation are performed at 1000RPM for 30 seconds, respectively.

Technical Field

The present application claims priority rights to korean patent application No. 10-2018-.

The present invention relates to a rotary platform device for qualitative and quantitative analysis of various heavy metals, and more particularly, to a device for qualitative and quantitative analysis of heavy metal samples in the form of a rotating disk.

Background

Typically, the most common heavy metal detection methods are spectroscopic analysis, such as inductively coupled plasma mass spectrometry or atomic absorption and emission spectrophotometers. Mass spectrometry-based heavy metal detection methods have accuracy and high detection limit, but they require expensive and skilled analysis techniques, making it difficult to perform heavy metal analysis quickly and simply on site.

Disclosure of Invention

Technical problem

In order to replace expensive mass spectrometry-based heavy metal analysis devices, it is necessary to develop an economical and inexpensive chromogenic-based heavy metal analysis system, and to develop a compact analysis system that can be conveniently used on site. In addition, it is required to develop a system capable of performing quantitative analysis and qualitative analysis on heavy metals while reducing analysis time by simultaneously detecting a plurality of heavy metals.

Technical scheme

The rotary stage apparatus for qualitative analysis and quantitative analysis according to the present invention may include:

a main injection part located near a rotation axis of the rotation platform and through which a fluid sample containing a heavy metal is injected;

a pH adjusting part for adjusting pH of the injected sample;

a detection part coated with a chelating agent capable of developing a color reaction with a heavy metal in a sample by diffusing the pH-adjusted sample; and

a scale for measuring a diffusion distance of the color reaction,

wherein the sample can be moved from the main injection part to the detection part through the pH adjustment part by rotation of the control means, and

among them, quantitative analysis can be performed by a color reaction of the heavy metal in the detection portion, and qualitative analysis can be performed by measuring a diffusion distance of the color reaction.

Advantageous effects

According to the qualitative analysis and quantitative analysis apparatus of an embodiment of the present invention, the detection limit of heavy metals can be improved by automatic control of the fluid and by adjusting the rotational force and the capillary force. The detection limit of the heavy metal ions can be improved by controlling the rotation force. That is, the detection limit can be increased by adjusting the centrifugal force and the capillary force by controlling the rotation to adjust the color development reaction time and the color development area.

In addition, according to the qualitative analysis and quantitative analysis apparatus of the embodiment of the present invention, qualitative analysis and quantitative analysis of a plurality of heavy metals can be performed in a single apparatus. According to the present invention, economical and rapid qualitative/quantitative analysis of various heavy metals can be achieved. It is more economical and can reduce the time required for analysis compared to conventional expensive spectroscopic or mass spectrometry based heavy metal detection devices. In addition, the structure for qualitative analysis and the structure for quantitative analysis are integrated into one small-sized device, so that it can be quickly and conveniently applied to the field requiring qualitative/quantitative analysis of heavy metals.

In addition, since each component such as the pH adjusting part, the detecting part, and the like is patterned in one apparatus, it is easy to manufacture a qualitative analysis and quantitative analysis apparatus.

In addition, according to the qualitative analysis and quantitative analysis apparatus of the embodiment of the present invention, by providing the air circulation channel, when the fluid sample is diffused in the detection part, the moisture of the detection part can be prevented from being condensed, so that the color development can be easily recognized and the analysis error can be minimized, and when the fluid sample is diffused in the detection part, the fluid sample can be more uniformly moved, so that the color development reaction can be more uniformly performed between the chelating agent coated on the detection part and the heavy metal of the sample.

Drawings

FIG. 1 illustrates a rotary platform apparatus for qualitative and quantitative analysis according to one embodiment of the present invention.

Fig. 2a to 2d illustrate respective layers of a rotary stage of the qualitative and quantitative analysis apparatus of fig. 1.

Fig. 3 illustrates a driving process of a rotary stage of the qualitative and quantitative analysis apparatus of fig. 1.

Fig. 4 is a photograph showing a case where a color reaction occurs when a sample is diffused on a rotating platform of the qualitative analysis and quantitative analysis device of fig. 1.

Fig. 5a to 5e show calibration curves of diffusion distances according to the coloration of heavy metal concentrations.

Fig. 6 illustrates a qualitative and quantitative analysis system in which the qualitative and quantitative analysis device of fig. 1 may be installed and rotated.

Detailed Description

The rotary stage apparatus for qualitative analysis and quantitative analysis according to the present invention may include:

a main injection part located near a rotation axis of the rotation platform and through which a fluid sample containing a heavy metal is injected;

a pH adjusting part for adjusting pH of the injected sample;

a detection part coated with a chelating agent capable of developing a color reaction with a heavy metal in a sample by diffusing the pH-adjusted sample; and

a scale for measuring a diffusion distance of the color reaction,

wherein the sample is moved from the main injection part to the detection part through the pH adjustment part by rotation of the device, and

wherein the quantitative analysis is realized by a color reaction of the heavy metal in the detection section, and the qualitative analysis is realized by measuring a diffusion distance of the color reaction.

In addition, in the rotary stage apparatus for qualitative analysis and quantitative analysis according to the present invention, the pH adjusting part may be filled with microbeads, and the surfaces of the microbeads may be coated with salt, so that the sample injected into the channel can be adjusted to have a desired pH.

In addition, the rotary stage apparatus for qualitative analysis and quantitative analysis according to the present invention may further include a storage region connecting the pH adjusting part and the sensing part, wherein one end of the sensing part may be received in the storage region.

In addition, in the rotary stage device for qualitative analysis and quantitative analysis according to the present invention, the pH adjusting part, the detecting part, and the scale may be provided in plurality, and each of the pH adjusting part, the detecting part, and the scale may be radially symmetrically provided on the rotary stage.

In addition, the rotary stage apparatus for qualitative analysis and quantitative analysis according to the present invention may further include: the main channel part is connected with one end of the main injection part; and a plurality of sample distribution channels connected to the main channel part, wherein each of the sample distribution channels may have a shape extending radially symmetrically from the main channel part.

In addition, in the rotary stage device for qualitative analysis and quantitative analysis according to the present invention, the main injection part may include a sample reservoir for storing an injected sample before being dispensed to each of the sample distribution channels, and the shape in which the sample reservoir and the main channel part are coupled may be a spiral shape.

In addition, the rotary stage apparatus for qualitative analysis and quantitative analysis according to the present invention may further include a plurality of on/off valves, each of which is disposed between each of the sample distribution channels and each of the pH adjustment parts, and the on/off valves may be opened by a rotational force of the rotary stage so that the sample contained in the sample distribution channel may pass through the pH adjustment parts.

In addition, the rotary stage apparatus for qualitative and quantitative analysis according to the present invention may further include a plurality of air circulation channels, each of which connects the respective storage regions with the other end of one of the sensing parts, and the air circulation channels may increase the evaporation rate of the fluid sample in the sensing parts and prevent moisture from condensing in the sensing parts.

In addition, in the rotary stage apparatus for qualitative analysis and quantitative analysis according to the present invention, the rotary stage may include:

a top layer including a main injection part, a main channel part, a sample distribution channel, an on/off valve, a pH adjustment part, and a storage region;

an intermediate layer including an air circulation passage and a storage region and having a partially opened shape corresponding to the detection part; and

a bottom layer including a storage area and a scale and having a space into which the detection part is inserted.

In addition, in the rotary stage device for qualitative analysis and quantitative analysis according to the present invention, the sample may be adjusted to have a pH most suitable for reacting the heavy metal contained in the sample with the chelating agent while passing through the microbeads filled in the pH adjustment part.

In addition, in the rotary stage device for qualitative analysis and quantitative analysis according to the present invention, the heavy metal contained in the sample may be Fe²⁺、Ni²⁺、Cu²⁺、Cr⁶⁺、Hg²⁺、As²⁺、Zn²⁺、Mn²⁺、Cd²⁺、Pb²⁺、Co²⁺Or Ag⁺。

In addition, in the rotary stage apparatus for qualitative and quantitative analysis according to the present invention, the chelating agent previously applied to the detection part may include bathophenanthroline (Bphen), Dimethylglyoxime (DMG), Dithiooxamide (DTO), Diphenylcarbazide (DPC), Dithizone (DTZ), chrome black t (ebt), or 1- (2-pyridylazo) -2-naphthol (PAN).

In addition, in the rotary stage apparatus for qualitative analysis and quantitative analysis according to the present invention, the rotation of the apparatus may be controlled by:

the apparatus is rotated for the first time and then stopped to move the sample injected into the main injection part to the sample distribution channel,

rotating the device a second time to move the sample moved to the sample distribution channel to the storage region through the pH adjusting part; and is

The rotation of the device is stopped to diffuse the sample moved to the storage area into the detection section.

In addition, in the rotary stage apparatus for qualitative analysis and quantitative analysis according to the present invention, the first rotation and the second rotation may be performed at 1000RPM for 30 seconds, respectively.