阅读说明：本技术 健康状态管理系统、健康状态管理系统的控制方法以及程序 (Health state management system, method for controlling health state management system, and program ) 是由 芦田竜太郎 伊利亚·玛琳 于 2017-11-30 设计创作，主要内容包括：本发明提供一种作为管理对象的被检测者能更简单且准确地直接测定其健康状态,而且利用该健康状态的测定数据,专业机构能更可靠地维持或改善被检测者的健康状态的技术。一种健康状态管理系统,具备：包括拉曼分光装置(2)和便携式终端(3)的测定终端(4)、服务器(5)以及医院终端(7),其中,便携式终端(3)将拉曼分光测定的测定数据发送至服务器(5),服务器(5)根据接收到的测定数据基于规定的判定算法判定牙齿的状态,发送至便携式终端(3)和医院终端(7)。此外,服务器(5)基于判定出的状态和登录信息,选择应就医的牙科医院,发送至便携式终端(3)。而且,还在便携式终端(3)和医院终端(7)进行作为能确定预约日期和时间的预约/受理支持。(The invention provides a technique by which a subject to be managed can directly measure the health condition of the subject more easily and accurately, and a professional can more reliably maintain or improve the health condition of the subject by using the measurement data of the health condition. A health state management system is provided with: the system comprises a measurement terminal (4) comprising a Raman spectroscopy device (2) and a portable terminal (3), a server (5), and a hospital terminal (7), wherein the portable terminal (3) transmits measurement data of Raman spectroscopy measurement to the server (5), and the server (5) determines the state of a tooth based on a predetermined determination algorithm based on the received measurement data and transmits the state to the portable terminal (3) and the hospital terminal (7). The server (5) selects a dental hospital to be treated based on the determined state and the registration information, and transmits the selected dental hospital to the portable terminal (3). Moreover, a reservation/acceptance support capable of specifying a date and time of reservation is also performed in the portable terminal (3) and the hospital terminal (7).)

1. A health state management system is provided with: a spectroscopic measurement device that irradiates a part of the body of a subject with light and detects scattered light or reflected light from the body of the subject to perform spectroscopic measurement; a terminal of a subject to which an output signal of the spectrometry device is input; an information processing device capable of communicating with the terminal of the subject; and a management means terminal provided in a management means for managing the health status of the subject, the management means terminal being capable of communicating with the subject terminal and the information processing apparatus,

the detected terminal has:

an input unit into which a measurement result measured by the spectrometry device is input; and

a transmission unit that transmits the measurement result input to the input unit to the information processing device,

the information processing apparatus includes:

a measurement information receiving unit that receives the measurement result transmitted from the transmitting unit of the subject terminal;

a determination unit configured to determine a health state of the subject based on the measurement result received by the measurement information reception unit and a predetermined algorithm; and

a determination information transmitting unit that transmits determination information that is information of a result determined by the determining unit,

the management agency terminal has a determination information receiving section,

receiving the determination information transmitted by a determination information transmitting section of the information processing apparatus,

the information processing apparatus further includes:

a schedule planning unit that makes a schedule for managing the health state of the subject based on the determination information; and

a predetermined information transmitting unit that transmits predetermined information, which is information predetermined for managing the health state of the subject specified by the predetermined planning unit, to the subject terminal and/or the administrative agency terminal,

the detected person terminal further has:

a second determination information receiving unit that receives the determination information transmitted by the determination information transmitting unit of the information processing apparatus; and

a predetermined information receiving section that receives the predetermined information transmitted by the predetermined information transmitting section of the information processing apparatus,

the authority terminal further has a second predetermined information receiving section,

receiving the predetermined information transmitted by the predetermined information transmitting unit of the information processing apparatus.

2. The health status management system according to claim 1,

the subject terminal has an additional information transmitting section for transmitting additional information related to the health status of the subject to the administrative agency terminal,

the management terminal further includes an additional information receiving unit that receives the additional information transmitted from the additional information transmitting unit of the subject terminal.

3. The health status management system according to claim 1 or 2,

the management mechanism terminal further includes a guidance information transmitting unit that transmits guidance information for guiding the subject to receive management by the management mechanism based on the determination information,

the detected terminal further includes a guidance information receiving unit that receives the guidance information transmitted by the guidance information transmitting unit.

4. The health status management system according to any one of claims 1 to 3,

the terminal of the detected person further comprises a personal information transmitting part for transmitting the personal information of the detected person to the information processing device,

the management organization terminal further includes an organization information transmitting unit that transmits organization information of the management organization to the information processing apparatus,

the information processing apparatus further includes:

a personal information receiving unit that receives the personal information;

a mechanism information receiving unit that receives the mechanism information;

a personal information storage unit that stores one or more pieces of personal information; and

a mechanism information storage unit for storing one or more pieces of the mechanism information,

the plan preparation unit prepares a management plan of the health state of the subject based on the personal information of the subject stored in the personal information storage unit and the institution information of the administrative institution stored in the institution information storage unit.

5. The health status management system according to claim 4,

the organization information includes information of the name, location and contact address of the management organization,

the personal information includes information of the residence of the subject,

the predetermined planning section selects a management organization whose location is close to the residence of the person to be examined,

the predetermined information includes at least any one of a name, a location, and a contact address of the selected management organization.

6. The health status management system according to any one of claims 1 to 5,

the subject terminal further includes a reservation information transmitting unit that transmits reservation information including a desired reservation day that is included in the reservation information and is desired to be reserved by the management institution selected by the reservation scheduling unit to the information processing apparatus and/or the management institution terminal,

the information processing apparatus and/or the management agency terminal further includes a reservation information receiving unit that receives the reservation information.

7. The health status management system according to any one of claims 1 to 6,

the spectroscopic measurement device is a raman spectroscopic device that performs spectroscopic measurement of raman scattered light from the subject using a raman spectroscopic technique.

8. The health status management system according to claim 7,

the information processing device includes a determination criterion storage unit that stores a relationship between a calculated value obtained by performing a predetermined calculation on at least one of a Raman scattered light intensity, a peak width, and a peak position at a predetermined frequency, and a health status of the subject,

the determination unit determines the health state of the subject based on an algorithm for deriving the health state of the subject corresponding to the measurement result by referring to the measurement result received by the measurement information reception unit in accordance with the relationship stored in the determination criterion storage unit.

9. The health status management system according to any one of claims 1 to 8,

the part of the subject's body is the subject's teeth,

the health state is a state of the teeth,

the regulatory agency is a dental hospital.

10. A method for controlling a health management system, the health management system comprising: a spectroscopic measurement device that irradiates a part of the body of a subject with light and detects scattered light or reflected light from the body of the subject to perform spectroscopic measurement; a terminal of a subject to which an output signal of the spectrometry device is input; an information processing device capable of communicating with the terminal of the subject; and a management entity terminal provided in a management entity that manages the health state of the subject, the management entity terminal being capable of communicating with the subject terminal and the information processing apparatus, the control method comprising:

a spectrometry step of performing spectrometry by the spectrometry device, the spectrometry being performed by irradiating a part of a body of a subject with light;

a measurement result transmission step of transmitting the measurement result measured in the spectroscopic measurement step from the subject terminal to the information processing apparatus;

a determination step of determining a health state of the subject in the information processing apparatus based on the measurement result and a predetermined algorithm;

a determination information transmission step of transmitting determination information, which is information of a result determined by the determination step, from the information processing apparatus to the terminal of the subject;

a step of planning reservation, which is to make a management reservation of the health state of the detected person based on the judgment information; and

a predetermined information transmission step of transmitting predetermined information, which is information scheduled for managing the health state of the subject determined by the predetermined planning step, from the information processing apparatus to the subject terminal.

11. The method of controlling a state of health management system according to claim 10,

the method further comprises an additional information transmission step of transmitting additional information related to the health status of the subject from the subject terminal to the administrative agency terminal.

12. The method of controlling a state of health management system according to claim 10 or 11, further comprising:

a determination information transmission step of transmitting determination information, which is information of a result determined by the determination step, from the information processing apparatus to the administrative terminal; and

and a guidance information transmission step of transmitting, from the management means terminal to the subject terminal, guidance information for guiding the subject to receive management by the management means, based on the determination information.

13. The method of controlling a state of health management system according to any one of claims 10 to 12, characterized by further comprising:

a personal information transmission step of transmitting personal information of the subject from the subject terminal to the information processing apparatus;

a mechanism information transmission step of transmitting mechanism information of the management mechanism from the management mechanism terminal to the information processing apparatus;

a personal information storage step of receiving one or more pieces of the personal information in the information processing apparatus, and storing and making a database thereof; and

an organization information storing step of receiving one or more pieces of the organization information in the administrative terminal, storing and making a database thereof,

in the plan planning step, a management plan for the health state of the subject is prepared based on the determination information, the personal information of the subject databased in the personal information storage step, and the institution information of the administrative institution databased in the institution information storage step.

14. The control method of a state of health management system according to any one of claims 10 to 13,

the organization information includes information of the name, location and contact address of the management organization,

the personal information includes information of the residence of the subject,

in the step of planning for reservation, a management institution whose location is close to the subject's residence is selected, and the reservation information includes at least any one of the name, location, and contact address of the selected management institution.

15. The control method of a state of health management system according to any one of claims 10 to 14,

the information processing apparatus further includes a reservation information transmission step of transmitting, from the subject terminal to the information processing apparatus and/or the management institution terminal, reservation information including a desired reservation day that is included in the reservation information and that is desired to be reserved by the management institution selected in the reservation scheduling step.

16. The control method of a state of health management system according to any one of claims 10 to 15,

in the spectroscopic measurement step, raman spectroscopic measurement is performed in which raman scattered light from the subject is spectroscopically measured by a raman spectroscopic technique.

17. The control method of a state of health management system according to any one of claims 10 to 16,

the method further comprises a determination criterion creating step of storing a determination criterion in which a relationship between a calculated value obtained by performing a predetermined calculation on at least one of a raman scattered light intensity, a peak width, and a peak position at a predetermined frequency and a health condition of the subject is stored,

the predetermined algorithm is an algorithm for deriving a health state of the subject corresponding to the measurement result by referring to the measurement result transmitted to the information processing device in the measurement result transmitting step, in accordance with the relationship stored in the determination criterion.

18. The control method of a state of health management system according to any one of claims 10 to 17,

the part of the subject's body is the subject's teeth,

the health state is a state of the teeth,

the regulatory agency is a dental hospital.

19. A process in which, in the presence of a catalyst,

a control method for causing at least any one of the subject terminal, the information processing apparatus, and the administrative terminal to execute the health status management system according to any one of claims 10 to 18.

Technical Field

The present invention relates to a health status management system for measuring and managing the health status of a subject using a spectroscopic technique, a method for controlling the health status management system, and a program.

Background

Conventionally, a method of analyzing a physical property value using a spectroscopic technique is known. As this technique, for example, a method for analyzing a physical property value of a polymer material is known, which is a method for analyzing a physical property value of a polymer material to be analyzed of the same kind as a specific polymer material based on a calibration curve showing a relationship between a raman spectrum value and a physical property value prepared in advance for the specific polymer material, and includes the steps of: measuring the Raman spectrum of the analyzed high polymer material; calculating the spectral value of the same kind as the standard high polymer material according to the Raman spectrum; and analyzing a physical property value corresponding to the spectral value using a standard (see patent document 1).

On the other hand, as a system for health management of a subject, a system is known which includes: a spectroscopic analyzer that irradiates the detection light to the food and receives the reflected light reflected from the food; a component analysis unit for analyzing the components of the food based on the reflected light; a quality detection unit for detecting the quality of the food; an identification section that identifies each acquirer by acquiring personal information that respectively specifies a plurality of acquirers; and a storage unit that stores personal information of each acquirer and a result of a component analysis of the food acquired by each acquirer, respectively, in units of acquirers (see patent document 2). This is a health management system that manages the results of analyzing the components of an object under examination acquired by a plurality of acquirers on an acquirer-by-acquirer basis.

Further, the following systems are known: the sensor includes a sensor case provided in a temple of a subject, the sensor case including: a biological optical measurement device for measuring a change in hemoglobin signal due to a change in function of a salivary line in the vicinity of the temple of the subject; and a mastication motion sensing device and a sensor control device that sense the motion of the temple due to mastication of the subject, simultaneously operate the biological optical measurement device and the mastication motion sensing device, transmit the measurement result to the operator system, and display the measurement result on a display device together with recommended information acquired from the operator system (see patent document 3).

The above-described conventional techniques cannot be said to be techniques by which the subject to be managed can directly measure the health state more easily and accurately. Further, it is not a technique for efficiently maintaining or improving the health condition of the subject by a professional institution such as a medical institution by effectively using the measurement data of the health condition.

Disclosure of Invention

Problems to be solved by the invention

The present invention has been made in view of the above circumstances, and an object of the present invention is to provide a technique by which a subject to be managed can directly measure the health state of the subject more easily and accurately, and a professional can maintain or improve the health state of the subject more efficiently using the measurement data of the health state.

Means for solving the problems

The present invention for solving the above-described problems is a health status management system including: a spectroscopic measurement device that irradiates a part of the body of a subject with light and detects scattered light or reflected light from the body of the subject to perform spectroscopic measurement; a terminal of a subject to which an output signal of the spectrometry device is input; an information processing device capable of communicating with the terminal of the subject; and a management entity terminal provided in a management entity that manages a health state of the subject, the management entity terminal being capable of communicating with the subject terminal and the information processing apparatus, the health state management system being characterized in that the subject terminal includes: an input unit into which a measurement result measured by the spectrometry device is input; and a transmission unit that transmits the measurement result input to the input unit to the information processing device, the information processing device including: a measurement information receiving unit that receives the measurement result transmitted from the transmitting unit of the subject terminal; a determination unit configured to determine a health state of the subject based on the measurement result received by the measurement information reception unit and a predetermined algorithm; and a determination information transmitting unit that transmits determination information that is information of a result determined by the determining unit, wherein the administrative terminal includes a determination information receiving unit that receives the determination information transmitted by the determination information transmitting unit of the information processing apparatus, and the information processing apparatus further includes: a schedule planning unit that makes a schedule for managing the health state of the subject based on the determination information; and a predetermined information transmitting unit that transmits predetermined information, which is information predetermined for managing the health state of the subject specified by the predetermined planning unit, to the subject terminal and/or the administrative terminal, wherein the subject terminal further includes: a second determination information receiving unit that receives the determination information transmitted by the determination information transmitting unit of the information processing apparatus; and a predetermined information receiving unit that receives the predetermined information transmitted by the predetermined information transmitting unit of the information processing apparatus, wherein the administrative terminal further includes a second predetermined information receiving unit that receives the predetermined information transmitted by the predetermined information transmitting unit of the information processing apparatus.

Thus, the subject can automatically acquire the result of the determination of the health state by only performing the spectroscopic measurement of a part of the body by the spectroscopic measurement device and transmitting the measurement result to the information processing device. Further, predetermined information predetermined for management of the determination result based on the health state can be automatically obtained. Therefore, the subject can more quickly maintain or improve the health status of the professional organization. Here, the determination result based on the health state includes a state determined to require management in the determination result.

Here, the spectroscopic measurement may be performed by simply irradiating the body of the subject with light and investigating the spectroscopic characteristics of the reflected light, or may be performed by detecting the peak of scattered light excited in accordance with the molecular structure of a part of the body of the subject. Here, as the healthy state, BMI, fat ratio, osteoporosis state, osteonecrosis state, and the like that can be estimated from the state of the teeth, the age of the skin, and the state of the skin of the subject can be exemplified, but the healthy state is not limited thereto.

In the above, as the management facilities, a hospital, various clinics, a professional facility such as a dental hospital and a consultant, and a care facility such as a nursing home can be exemplified. Further, as the management reservation of the health status, a medical reservation for going to a management institution, an interview reservation with an expert of the management institution, and the like are included.

In the present invention, it is also possible to: the subject terminal includes an additional information transmitting unit that transmits additional information related to the health status of the subject to the administrative terminal, and the administrative terminal further includes an additional information receiving unit that receives the additional information transmitted from the additional information transmitting unit of the subject terminal.

Here, the additional information may be an explanation, an image, or the like of a symptom associated with a measurement result measured by the spectroscopic measurement apparatus. Or, it may be an associated advisory message, etc. This enables more detailed and flexible information exchange between the management organization and the subject, and more reliable maintenance and management of the health condition of the subject.

In the present invention, it is also possible to: the management mechanism terminal further includes a guidance information transmitting unit that transmits guidance information for guiding the subject to receive management by the management mechanism based on the determination information, and the subject terminal further includes a guidance information receiving unit that receives the guidance information transmitted by the guidance information transmitting unit.

Here, the guidance information may refer to, for example, a guidance message of a hospital arrival sent by the hospital to the subject. Further, a medicine taking instruction message or the like may be issued to the subject from a hospital or the like. Thus, the management means can provide more detailed guidance and guidance to the subject, and the health condition of the subject can be reliably maintained or managed.

In the present invention, it is also possible to: the subject terminal further includes a personal information transmitting unit that transmits the personal information of the subject to the information processing apparatus, the administrative agency terminal further includes a mechanism information transmitting unit that transmits the mechanism information of the administrative agency to the information processing apparatus, and the information processing apparatus further includes: a personal information receiving unit that receives the personal information; a mechanism information receiving unit that receives the mechanism information; a personal information storage unit that stores one or more pieces of personal information; and a mechanism information storage unit that stores one or more pieces of the mechanism information, wherein the schedule planning unit makes a management schedule of the health state of the subject based on the personal information of the subject stored in the personal information storage unit and the mechanism information of the management mechanism stored in the mechanism information storage unit.

That is, in the health state management system of the present invention, the personal information of the subject is transmitted from the subject terminal to the information processing apparatus and registered. Further, the organization information of the organization is transmitted from the organization terminal to the information processing apparatus and registered. These pieces of information are made into a database in the information processing apparatus. In addition to the above determination result, the information processing device also creates a management plan for the health state of the subject based on the personal information of the subject and the institution information of the administrative institution, which are made into a database. For example, a management reservation for hospitalization at a hospital which is a special hospital associated with the determination result and is in the same area as the residence of the subject may be made.

In the present invention, it is also possible to: the institution information includes information on a name, a location, and a contact address of the administrative institution, the personal information includes information on a residence of the person to be detected, the predetermined planning unit selects an administrative institution whose location is close to the residence of the person to be detected, and the predetermined information includes at least one of the selected name, location, and contact address of the administrative institution. This makes it easier to establish a management plan for the health state of the subject.

In the present invention, it is also possible to: the subject terminal further includes a reservation information transmitting unit that transmits reservation information including a desired reservation day that is included in the reservation information and is desired to be reserved in the management institution selected by the reservation scheduling unit to the information processing apparatus and/or the management institution terminal, and the information processing apparatus and/or the management institution terminal further includes a reservation information receiving unit that receives the reservation information. Thus, the person to be examined can more easily specify the reservation to the management agency by the reservation information transmitted from the information processing device. This can more rapidly promote the maintenance or improvement of the health condition of the subject.

In the present invention, the spectroscopic measurement apparatus may employ a raman spectroscopic apparatus that performs spectroscopic measurement of raman scattered light from the subject using raman spectroscopy. This makes it possible to perform spectroscopic measurement with higher correlation from the molecular structure of a part of the body of the subject, and to determine the health state with higher accuracy.

In the present invention, it is also possible to: the information processing device includes a criterion storage unit that stores a relationship between a calculated value obtained by performing a predetermined operation on at least one of a raman scattered light intensity, a peak width, and a peak position at a predetermined frequency and a health state of the subject, and the determination unit determines the health state of the subject based on an algorithm that refers to the measurement result received by the measurement information reception unit and derives the health state of the subject corresponding to the measurement result in accordance with the relationship stored in the criterion storage unit.

Here, in raman scattering spectrometry, at least one of the peak position, the peak intensity, and the peak width of a specific wave number shift is measured, and it is known that a calculated value obtained by performing a predetermined operation on these values has a high correlation with the health state of a biological sample. In the present invention, the relationship between the calculated value having the high correlation and the health state of the biological sample is used to determine the health state of the subject. This makes it possible to determine the health condition of the subject with extremely high accuracy.

In the present invention, it is also possible to: the part of the subject's body is the subject's teeth, the health state is the state of the teeth, and the regulatory agency is a dental hospital.

Here, it is found that the diagnosis of the tooth can be performed with very high accuracy by raman scattering spectrometry. Therefore, according to the present invention, for example, the state of the tooth can be determined with very high accuracy at home. In addition, the system can be efficiently connected with a plurality of dental hospitals in the region, and effectively promote the prevention and treatment of diseases such as dental caries and the like.

Further, the present invention may be a method for controlling a health management system including: a spectroscopic measurement device that irradiates a part of the body of a subject with light and detects scattered light or reflected light from the body of the subject to perform spectroscopic measurement; a terminal of a subject to which an output signal of the spectrometry device is input; an information processing device capable of communicating with the terminal of the subject; and a management entity terminal provided in a management entity that manages the health state of the subject, the management entity terminal being capable of communicating with the subject terminal and the information processing apparatus, the control method comprising: a spectrometry step of performing spectrometry by the spectrometry device, the spectrometry being performed by irradiating a part of a body of a subject with light; a measurement result transmission step of transmitting the measurement result measured in the spectroscopic measurement step from the subject terminal to the information processing apparatus; a determination step of determining a health state of the subject in the information processing apparatus based on the measurement result and a predetermined algorithm; a determination information transmission step of transmitting determination information, which is information of a result determined by the determination step, from the information processing apparatus to the terminal of the subject; a step of planning reservation, which is to make a management reservation of the health state of the detected person based on the judgment information; and a predetermined information transmission step of transmitting predetermined information, which is information predetermined for managing the health state of the subject determined by the predetermined planning step, from the information processing apparatus to the subject terminal.

The present invention may be the method for controlling the health status management system, further comprising an additional information transmission step of transmitting additional information related to the health status of the subject from the subject terminal to the administrative terminal.

The present invention may also be the method for controlling the health status management system, further including: a determination information transmission step of transmitting determination information, which is information of a result determined by the determination step, from the information processing apparatus to the administrative terminal; and a guide information transmission step of transmitting, from the management means terminal to the subject terminal, guide information for guiding the subject to receive management by the management means, based on the determination information.

The present invention may also be the method for controlling the health status management system, further including: a personal information transmission step of transmitting personal information of the subject from the subject terminal to the information processing apparatus; a mechanism information transmission step of transmitting mechanism information of the management mechanism from the management mechanism terminal to the information processing apparatus; a personal information storage step of receiving one or more pieces of the personal information in the information processing apparatus, and storing and making a database thereof; and an institution information storage step of receiving one or more pieces of the institution information in the administrative terminal, and storing and making a database of the received one or more pieces of the institution information, wherein in the plan scheduling step, a management plan for the health state of the subject is prepared based on the determination information, the personal information of the subject made a database in the personal information storage step, and the institution information of the administrative institution made a database in the institution information storage step.

In the method for controlling a health status management system according to the present invention, the institution information may include information on a name, a location, and a contact address of the administrative institution, the personal information may include information on a residence of the subject, the predetermined planning step may select an administrative institution whose location is close to the residence of the subject, and the predetermined information may include at least one of the selected name, location, and contact address of the administrative institution.

The present invention may be the method for controlling a health status management system described above, further comprising a reservation information transmission step of transmitting, from the subject terminal to the information processing apparatus and/or the management institution terminal, reservation information including a desired reservation day that is included in the reservation information and that is desired to be reserved for the management institution selected in the reservation planning step.

The present invention may be the method for controlling the health status management system, wherein in the spectroscopic measurement step, raman spectroscopic measurement for performing spectroscopic measurement of raman scattered light from the subject using a raman spectroscopic technique is performed.

The present invention may be the control method of the health state management system described above, further comprising a determination criterion creating step of storing a determination criterion in the information processing device, the determination criterion storing a relationship between a calculated value obtained by performing a predetermined operation on at least one of a raman scattered light intensity, a peak width, and a peak position at a predetermined frequency and the health state of the subject, wherein the predetermined algorithm is an algorithm for deriving the health state of the subject corresponding to the measurement result by referring to the measurement result transmitted to the information processing device in the measurement result transmitting step, in accordance with the relationship stored in the determination criterion.

The present invention may be the control method of the health state management system, wherein the part of the body of the subject is a tooth of the subject, the health state is a state of the tooth, and the management institution is a dental hospital.

The present invention may be a program for causing at least one of the subject terminal, the information processing apparatus, and the administrative terminal to execute the control method of the health status management system.

In the present invention, the above-described means for solving the problem can be used in combination as much as possible.

Effects of the invention

According to the present invention, the subject to be managed can directly measure the health condition of the subject more easily and accurately, and a professional administration agency can maintain or improve the health condition of the subject more efficiently by using the measurement data of the health condition.

Drawings

Fig. 1 is a diagram showing an overview of a health state management system according to an embodiment of the present invention.

Fig. 2 is a schematic diagram of a configuration of a raman spectroscopic device according to an embodiment of the present invention.

Fig. 3 is a diagram showing a hard configuration of the health state management system according to the embodiment of the present invention.

Fig. 4 is a diagram showing a functional configuration of a health state management system according to an embodiment of the present invention.

FIG. 5 is a flow diagram of a metering routine of an embodiment of the present invention.

FIG. 6 is a flow diagram of a decision routine of an embodiment of the present invention.

FIG. 7 is a flow diagram of a reservation planning routine of an embodiment of the present invention.

Fig. 8 is a flowchart of a reservation acceptance support routine according to an embodiment of the present invention.

Fig. 9 is a graph showing the wave number distribution of raman scattered light intensity on the surface of a tooth according to an example of the present invention.

Fig. 10 is a graph showing the relationship between the Qt value and the degree of damage of the tooth according to the example of the present invention.

Fig. 11 is a second graph showing the wave number distribution of raman scattered light intensity on the surface of a tooth according to an embodiment of the present invention.

Fig. 12 is a graph showing a relationship between a calculated value RPF of raman scattered light intensity on the surface of skin and an age of a skin provider according to an embodiment of the present invention.

Fig. 13 is a graph showing a relationship between the calculated raman scattered light intensity R L C/BMI on the skin surface and the age of a skin provider according to an embodiment of the present invention.

Fig. 14 is a graph showing the distribution of the peak position and the peak intensity of phenylalanine in the raman scattered light intensity on the bone surface according to the example of the present invention, depending on the bone state.

Fig. 15 is a second graph showing the difference in the peak position and the distribution of the peak intensity of sphingomyelin in the raman scattered light intensity on the bone surface according to the example of the present invention, depending on the bone state.

Detailed Description

Hereinafter, embodiments of the present invention will be described with reference to the drawings. The embodiments described below are merely examples of implementing the present invention, and the present invention is not limited to the specific configurations described below.

[ example ]

< overview of health management System >

Fig. 1 is a diagram showing a health management system 1 according to the present embodiment. The health management system 1 includes: a measurement terminal 4 including the raman spectroscopic device 2 and the portable terminal 3, a server 5 storing a database of various information, and a hospital terminal 7 that manages patients by an electronic medical record card or the like. In the present embodiment, the health management system 1 corresponds to a health state management system. The raman spectroscopic device 2 corresponds to a spectroscopic measurement device. The portable terminal 3 corresponds to a terminal of a subject. The server 5 corresponds to an information processing apparatus. The hospital terminal 7 corresponds to a management institution terminal.

The raman spectroscopic device 2 in the measurement terminal 4 has a configuration as shown in fig. 2, for example. As shown in fig. 2, since the excitation light for exciting raman scattering is required to be light of a stable single wavelength, a laser light source 2a is used as the light source. The excitation light is reflected by the mirror 2b, then bent at 90 degrees at the beam splitter 2d, and passes through the objective optical system 2c, thereby being condensed on the subject.

Then, part of the reflected light of the object enters the filter 2e through the objective optical system 2c and the beam splitter 2 d. Here, part of the reflected light of the subject is rayleigh scattered light or the like. In addition, the reflected light includes raman scattered light generated by raman scattering in which the wave number of the excitation light shifts according to the molecular structure of the object. Then, the reflected light enters the filter 2e, and rayleigh scattered light and the like are cut off. The reflected light having passed through the filter 2e enters the beam splitter 2 f. The reflected light is split into individual wave numbers (wavelengths) by a diffraction grating or the like in the beam splitter 2 f. The dispersed raman scattered light is irradiated to the photodetector 2 g. Raman scattered light can be detected by the photodetector 2 g.

The description returns to fig. 1. In the health management system 1 of the present embodiment, the measurement terminal 4 can download a dedicated application program from the mobile terminal 3 to control the raman spectroscopic device 2, acquire an output signal of the raman spectroscopic device 2, and transmit the output signal to the server 5. Moreover, personal data of the subject, such as name, address, sex, age, etc., can be registered in the server 5 using a dedicated application in the portable terminal 3.

A determination algorithm (described later) for determining the state of the tooth of the subject based on the measurement data of the raman spectroscopic device 2 is introduced into the server 5. In addition, the personal data transmitted from the plurality of mobile terminals 3 is made into a database and stored. As described later, information of the dental hospital, such as a name, a location, an e-mail address, and the like, is transmitted from the hospital terminal 7, and the information of the dental hospital is databased and stored in the server 5.

Further, determination result data on the state of the tooth determined by the determination algorithm is transmitted from the server 5 to the portable terminal 3 and the hospital terminal 7. The server 5 stores a selection algorithm for comparing the personal data transmitted from the mobile terminal 3 with a database storing hospital data of a dental hospital transmitted from the hospital terminal 7 and selecting a dental hospital suitable for the subject. Then, determination result data on the state of the tooth determined by the determination algorithm and the dental hospital information selected by the selection algorithm are transmitted from the server 5 to the portable terminal 3. As a selection criterion of the dental hospital based on the selection algorithm, the distance between the location of the dental hospital and the residence of the subject may be used as a criterion, or a professional area or a holding facility corresponding to the state of the teeth may be used as a criterion. In addition, other main factors may be used as a reference.

Further, information on the hospital arrival desire date of the subject is exchanged between the server 5 and the mobile terminal 3, and information on the available reservation date is exchanged between the server 5 and the hospital terminal 7, whereby the subject makes a hospital reservation and receives support. Further, the medical information can be managed by exchanging actual medical information with the mobile terminal 3 and the hospital terminal 7.

Further, a consultation message about health management of teeth including the state of the teeth can be transmitted from the portable terminal 3 to the hospital terminal 7, and a guidance message recommending a visit to a dental hospital can be transmitted from the hospital terminal 7 to the portable terminal 3. Here, the process of transmitting the consultation message from the portable terminal 3 to the hospital terminal 7 corresponds to the additional information transmission step in the present embodiment. Further, the process of transmitting the guidance message recommending the visit to the dental hospital from the hospital terminal 7 to the portable terminal 3 corresponds to the guidance information transmitting step in the present embodiment.

Further, the server 5 transmits determination result data, which is information of the determination result of the state of the tooth, to the hospital terminal 7. An electronic medical record card concerning a subject is created and stored in the hospital terminal 7. Further, the server 5 can assist the examination of the subject when he/she actually comes to the hospital.

Here, the mobile terminal 3 may be a smartphone, the mobile terminal 3 may be a tablet terminal, smart glasses, a wearable device, or the like, the server 5 is a computer connected to the Network via AN internet line, the hospital terminal 7 is a personal computer connected to the Network via AN internet line, for example, L AN (L local Area Network), WAN (Wide Area Network), or another packet communication Network may be used instead of the internet N.

< hardware construction >

Fig. 3 is a diagram illustrating a hardware configuration of each apparatus of the present embodiment. Fig. 3 shows the hardware configuration of the portable terminal 3, the server 5, and the hospital terminal 7.

The mobile terminal 3 is a terminal such as a smartphone, and includes AN auxiliary storage device 34 such as a CPU (Central Processing Unit) 31, a RAM (Random Access Memory) 32, a ROM (Read Only Memory) 33, and AN SSD (Solid State Drive), a communication Unit 35 connected to the internet N, AN operation Unit 36 such as a touch panel, and a display Unit 37 such as a display, and the communication Unit 35 may be connected to the internet N via a mobile phone communication Network such as L TE (L ong Term Evolution) in addition to AN NIC (Network interface controller) connected to the internet N via AN Access point such as a wireless L AN.

The CPU31 is a central processing device that controls the RAM32, the secondary storage device 34, and the like by processing commands and data expanded in the RAM32 and the like. The RAM32 is a main storage device, and is controlled by the CPU31 to write and read various commands and data. The auxiliary storage device 34 is a nonvolatile storage device, and stores various programs, data that needs to be permanently stored, and the like.

The server 5 is a computer including a CPU51, a RAM52, a ROM53, an auxiliary storage device 54 such as a HDD (Hard Disk Drive), and a communication unit 55 connected to the internet N via a gateway or the like. Although the server 5 is illustrated as one computer in fig. 3, the server 5 may be configured by a plurality of computers connected via a network, for example.

The hospital terminal 7 is a computer including a CPU71, a RAM72, a ROM73, an auxiliary storage device 74 such as an HDD, a communication unit 75 connected to the internet N via a gateway or the like, an operation unit 76 such as a keyboard and a mouse, and a display unit 77 such as a display. Note that, although not shown, the hospital terminal 7 is connected to a printer that performs printing.

< functional constitution >

Fig. 4 is a diagram illustrating a functional configuration of each device according to the present embodiment. Fig. 4 illustrates the main functions of the portable terminal 3, the server 5, and the hospital terminal 7.

(function of Portable terminal 3)

In the mobile terminal 3, programs such as a health management application stored in the auxiliary storage device 34 are read out to the RAM32 and executed by the CPU 31. Thus, the mobile terminal 3 functions as a computer including the input unit F31, the transmission unit F32, the scheduled information receiving unit F33, the second determination information receiving unit F34, the additional information transmission unit F35, the guidance information receiving unit F36, the personal information transmission unit F37, and the reservation information transmission unit F38.

In the present embodiment, each function provided in the mobile terminal 3 is executed by the CPU31 which is a general-purpose processor, but a part or all of the functions may be executed by one or more dedicated processors, a hardware arithmetic circuit, or the like. Here, the hardware arithmetic circuit refers to, for example, an adder circuit, a multiplier circuit, a flip-flop, and the like, in which logic gates are combined. In addition, a part or all of the functions may be executed by another computer.

The input unit F31 receives measurement data from the raman spectroscopic device 2. The transmitter F32 also transmits the measurement data input to the input F31 to the server 5. The predetermined information receiving unit F33 receives the predetermined information for health management of the examinee, which is prepared by the predetermined planning unit F54 of the server 5 and transmitted by the predetermined information transmitting unit F55. The second judgment information receiver F34 receives the judgment result data judged by the judgment unit F52 of the server 5 and transmitted by the judgment information transmitter F53. The additional information transmitting unit F35 transmits additional information related to the health status of the subject. The guidance information receiving unit F36 receives the guidance information transmitted by the guidance information transmitting unit F74 of the hospital terminal 7. The personal information transmitting unit F37 transmits the personal data of the subject to be registered in the personal information database D501 in the server 5. The reservation information transmitting part F38 transmits reservation information including the date and time of the desired reservation to the dental hospital selected in the reservation planning part F54 of the server 5.

(function of Server 5)

The server 5 reads out the program stored in the auxiliary storage device 54 to the RAM52 and executes it by the CPU51, thereby functioning as a computer including the personal information database D501, the facility information database D502, the determination information database D503, the measurement information receiving unit F51, the determination unit F52, the determination information transmitting unit F53, the schedule scheduling unit F54, the schedule information transmitting unit F55, the personal information receiving unit F56, the facility information receiving unit F57, and the reservation information receiving unit F58.

Personal data as personal information transmitted from one or more mobile terminals 3 and registered therein is stored in the personal information database D501. The personal information database D501 corresponds to a personal information storage unit. The institution information database D502 stores hospital data as institution information transmitted from one or more hospital terminals 7. The mechanism information database D502 corresponds to a mechanism information storage unit. The judgment information database D503 stores a relationship between a calculated value obtained by calculating the measurement data and the state of the tooth. This relationship corresponds to a criterion. The determination information database D503 corresponds to a determination criterion storage unit. The databases are constructed by managing data stored in the auxiliary storage device 54 by a program of a database management system.

The measurement information receiver F51 receives the measurement data of raman spectroscopic measurement transmitted from the transmitter F32 of the mobile terminal 3. The determination unit F52 determines the state of the tooth with reference to the determination information database D503 with respect to the spectroscopic measurement data received by the measurement information receiving unit F51. The determination information transmitting unit F53 transmits determination result data as information of the result determined by the determining unit F52. The planning unit F54 refers to the personal data of the subject in the personal information database D501 and the hospital data in the institution information database D502, selects a dental hospital where the subject should attend for the purpose of health management of teeth, and generates the planning information. The schedule information transmitter F55 transmits the schedule information generated by the schedule scheduler F54. The personal information receiver F56 receives the personal data of the subject transmitted from the personal information transmitter F37 of the portable terminal 3. The institution information receiving unit F57 receives the hospital data of the dental hospital transmitted from the institution information transmitting unit F75 of the hospital terminal 7. The reservation information receiving unit F58 receives reservation information such as a date and time desired to be reserved, which is transmitted from the mobile terminal 3.

(function of Hospital terminal 7)

The hospital terminal 7 reads out the program stored in the auxiliary storage device 74 to the RAM72 and executes it by the CPU71, thereby functioning as a computer including the determination information receiving unit F71, the second scheduled information receiving unit F72, the additional information receiving unit F73, the guidance information transmitting unit F74, the facility information transmitting unit F75, and the reservation information receiving unit F76. Some or all of the functions of the hospital terminal 7 may be executed by one or more dedicated processors, hardware arithmetic circuits, or the like.

The judgment information receiver F71 receives the judgment result data judged by the judgment unit F52 of the server 5 and transmitted by the judgment information transmitter F53. The second predetermined information receiving part F72 receives the predetermined information for health management of the examinee, which is made by the predetermined planning part F54 of the server 5 and transmitted by the predetermined information transmitting part F55. The additional information receiving unit F73 receives the additional information on the health status of the subject transmitted from the additional information transmitting unit F35 of the portable terminal 3. The guidance information transmitter F74 transmits guidance information including a message recommending a hospital to be got in to the subject based on the determination information transmitted from the determination information transmitter F53 of the server 5. The facility information transmitting unit F75 transmits hospital data of the dental hospital. The reservation information receiving unit F76 receives reservation information such as a date and time desired to be reserved, which is transmitted from the mobile terminal 3.

Next, the control of the measurement terminal 4 will be described. Fig. 5 is a flowchart of a measurement routine executed when raman spectroscopy is performed according to the present embodiment. The measurement routine is a program downloaded via the internet and constituting a part of the health management application stored in the auxiliary storage device 34 of the mobile terminal 3.

When this routine is executed, first, in step S301, the raman spectroscopic device 2 is in a request state for activation, and the portable terminal 3 displays an input request screen indicating whether or not the raman spectroscopic device 2 is activated. Then, the user touches the start button, thereby acquiring an instruction of start of the raman spectroscopic device 2. Thereby, the laser light source 2a is turned on, and the raman spectroscopic device 2 is in a state capable of performing measurement. When the process of step S301 ends, the process proceeds to step S302.

In step S302, a setting of a measurement purpose is requested. More specifically, the portable terminal 3 displays options for measurement purposes, and displays a screen requesting selection of any of the options. Then, the user selects an appropriate purpose, thereby setting the measurement purpose. When the process of step S302 ends, the process proceeds to step S303.

In step S303, a measurement position is set. More specifically, the selection of which portion of which tooth to measure is made. When the process of step S303 ends, the process proceeds to step S304.

In step S304, the excitation light of the raman spectroscopic device 2 is actually irradiated to the site specified in step S303, and the raman scattered light is received. The received raman scattered light is sensed by increasing the output signal from the photodetector 2g of the raman spectroscopic device 2 above a threshold value. Here, when it is not determined that the raman scattered light is received, the process is repeated until it is determined that the raman scattered light is received before returning to the process. If it is determined that the raman scattered light is received, the process proceeds to step S305.

In step S305, it is determined whether or not the received light intensity of the raman scattered light detected by the photodetector 2g is within a predetermined range. Here, when the excitation light of the raman spectrometer 2 is irradiated, but raman scattered light having a sufficient intensity for measurement cannot be obtained due to the relationship of the irradiation angle, the distance, and the like, the irradiation angle, the distance, and the like are changed and adjusted so that a sufficient received light intensity is obtained. Here, when it is determined that the light reception intensity within the predetermined range is not obtained, the processing of step S304 and the processing of step S305 are repeatedly executed until it is determined that the light reception intensity within the predetermined range is obtained in step S305, before returning to the processing of step S304. If the received light intensity in the predetermined range is obtained in step S305, the process proceeds to step S306.

In step S306, it is determined whether or not the measurement is continued for another position. Specifically, a screen for presenting whether or not to select measurement at another position is displayed on the mobile terminal 3. Then, the user selects yes or no, thereby determining whether to continue the measurement of the other position. Here, if the user selects yes, the process returns to step S303. On the other hand, if the user selects no, the process proceeds to step S307.

The measurement is ended in step S307. More specifically, the power supply of the raman spectroscopic device 2 is cut off, and a screen showing the end of measurement is displayed on the screen of the portable terminal 3. When the process of step S307 ends, the process proceeds to step S308.

In step S308, the measurement data as the measurement result is transmitted to the server 5. When the process of step S308 ends, the process proceeds to step S309.

In step S309, the determination result data as the determination information is transmitted from the server 5 and received by the mobile terminal 3. Step S310 is entered when the reception ends. In step S310, the state of the tooth is displayed on the portable terminal 3. When the processing in step S310 ends, the present routine is temporarily ended. In the above-described measurement routine, the processing of steps S301 to S307 corresponds to the spectroscopic measurement step of the present embodiment. The process of step S308 corresponds to a measurement result transmission step.

Next, the determination process in the server 5 will be described. A flowchart of the determination routine of the present embodiment is shown in fig. 6.

When this routine is executed, first, measurement data is received from the mobile terminal 3 in step S501. When the process of step S501 ends, the process proceeds to step S502. In step S502, the personal information database D501 is accessed to identify the subject. When the process of step S502 ends, the process proceeds to step S503. In step S503, the measurement data is analyzed by the determination algorithm. This analysis method will be described in detail later. The state of the tooth is analyzed by the analysis of step S503. Here, the measurement data and the determination result data are stored in association with the personal data in the personal information database D501 together with the date and time. When the process of step S503 ends, the process proceeds to step S504.

In step S504, the determination result data is transmitted to the portable terminal 3. When the processing in step S504 ends, the present routine is temporarily ended. In the above-described determination routine, the process of step S503 corresponds to the determination step. The process of step S504 corresponds to the determination information transmission step.

Next, a predetermined scheduling process in the server 5 will be described. A flowchart of the predetermined planning routine of the present embodiment is shown in fig. 7.

When this routine is executed, in step S511, personal data of the subject is registered in the server 5. This can be done by setting a login function in advance in the health management application downloaded to the portable terminal 3, and inputting the personal data of the subject into the portable terminal 3 to give a login instruction by the user selecting to execute the login function. Examples of the personal data include name, age, sex, address, contact information, and medical record. As the contact means, a telephone number, a Facsimile (FAX) number, and an email address can be exemplified. Here, the transmitted personal data is stored in the auxiliary storage device 54 as data of the personal information database D501 of the server 5. When the process of step S511 ends, the process proceeds to step S512.

In step S512, hospital data of the dental hospital is registered in the server 5. This is performed by executing a registration function in the hospital terminal 7, inputting hospital data of the dental hospital into the hospital terminal 7, and giving a registration instruction. Examples of the hospital data include the name, location, professional field, owned equipment, and contact address of the hospital. As the contact means, a telephone number, a facsimile number, an e-mail address can be exemplified. Here, the transmitted hospital data is stored in the auxiliary storage device 54 as data of the facility information database D502 of the server 5. When the process of step S512 ends, the process proceeds to step S513.

In step S513, a dental hospital to be hospitalized is selected based on the information on the residence of the subject in the personal information database D501 and the location of the dental hospital in the institution information database D502. More specifically, a dental hospital located in the same county as the residence of the subject is selected at a time. In this way, even if the number of the residences is not reduced to an appropriate number, the number of the residences is reduced to an appropriate number such that the residences are located in the same city as the residence of the subject and in the same town as the residence of the subject. The number may be multiple or one. When the process of step S513 ends, the flow proceeds to step S514.

In step S514, the hospital data of the selected dental hospital is transmitted to the portable terminal 3. When the processing in S514 is finished, the present routine is temporarily finished. In the above-described scheduled scheduling routine, the processing of step S511 corresponds to a personal information transmission step and a personal information storage step. The processing of step S512 corresponds to a mechanism information transmission step and a mechanism information storage step. The process of step S513 corresponds to a predetermined planning step. The process of step S514 corresponds to a predetermined information transmission step. Further, the hospital data of the selected dental hospital corresponds to predetermined information.

In the above predetermined planning process, a dental hospital to be treated is selected based on the present value of the dental hospital. However, the selection criteria of the dental hospital are not limited thereto. For example, a dental hospital may be selected based on a required professional field or a holding facility by referring to the determination result data of raman spectroscopy. Alternatively, the selection may be performed by combining these criteria.

Next, after selecting a dental hospital to be visited, the selected dental hospital may be reserved and accepted for support. Fig. 8 is a flowchart of a reservation acceptance support routine executed in this case. In executing the present routine, first, in step S521, a desired reservation date of the subject as reservation information is transmitted. More specifically, when the health management application is executed, a screen requesting input of a date and time desired to be reserved is displayed on the portable terminal 3. At this time, priority order such as desired date and time 1, 2, 3 may be requested to be given. After the date and time desired to be reserved is input, the user presses a transmission button, whereby information on the date and time desired to be reserved is transmitted from the portable terminal 3 to the server 5. When the process of step S521 ends, the process proceeds to step S522.

In step S522, information of the date and time of the dental treatment appointment is transmitted from the hospital terminal 7 to the server 5. When the process of step S522 ends, the process proceeds to step S523.

In step S523, the date and time of reservation is determined in the server 5. More specifically, the date and time information of the date and time to be reserved, which is transmitted from the portable terminal 3 and received by the hospital terminal 7, is referred to as the date and time to be reserved, which is transmitted from the hospital terminal 7, from the higher priority side. Then, a date and time that matches the first reservable date and time among the dates and times desired to be reserved is determined as the reservation date and time. When the process of step S523 ends, the process proceeds to step S524. In step S524, the information on the date and time of the reservation described above is transmitted from the server 5 to the portable terminal 3 and the hospital terminal 7. When the processing of step S524 ends, the present routine is temporarily ended. In the reservation acceptance support routine described above, the processing of step S523 corresponds to a scheduling step. The process of step S524 corresponds to a predetermined information transmission step.

Thus, in order to manage the state of the teeth of the subject, not only can a dental hospital be selected, but also the appointment/acceptance can be completed quickly. Therefore, the health condition of the subject can be maintained and improved more efficiently. Note that: in the above-described reservation acceptance support routine, the date and time to be reserved is transmitted from the mobile terminal 3 to the server 5 and the hospital terminal 7, the date and time to be reserved is specified at the hospital terminal 7, and the specified date and time to be reserved is transmitted from the hospital terminal 7 to the server 5 and the mobile terminal 3. Alternatively, it is also possible to: the date and time that can be reserved is transmitted from the hospital terminal 7 to the server 5 and the portable terminal 3, the date and time of reservation is determined at the portable terminal 3, and the determined date and time of reservation is transmitted from the portable terminal 3 to the server 5 and the hospital terminal 7.

Further, it is also possible to provide: after that, the information is transmitted from the portable terminal 3 or the hospital terminal 7 to the server 5 in a case where the subject actually goes to the dental hospital. The server 5 stores the medical history in the auxiliary storage device 54 in association with the personal information database D501 and the facility information database D502. This enables management of scheduled progress, i.e., management of medical information, in the server 5.

Next, an outline of a determination algorithm for determining the state of the tooth from the measurement data of the raman scattered light will be described. As described above, the raman scattered light causes a wave number shift corresponding to the molecular structure of the object to the excitation light. Fig. 9 shows an example of spectroscopic measurement results of raman scattered light in the case where excitation light is irradiated onto the surface of a tooth. The horizontal axis represents the wave number shift, and the vertical axis represents the light reception intensity of the normalized raman scattered light.

In the present embodiment, the state of caries is determined using the state coefficient Qt shown in the following formula (1).

[ equation 1]

Here, Qt is a state coefficient of a specific tooth, I is an integrated area intensity of a peak of a specific wave number shift, W is a width of a peak of a specific wave number shift, and Wr is a width of a reference peak with respect to pure hydroxyapatite or intact enamel, α and β are coefficients of 0 to 1 inclusive that correct relative intensities of sub-bands.

In the present embodiment, the graph is used to determine that the tooth is healthy when the value of the state coefficient Qt is 0.01 or less, to determine that the state is at a low risk when the value of the state coefficient Qt is in the range of 0.01 to 0.03, to determine that the state is at a high risk when the value of the state coefficient Qt is in the range of 0.03 to 0.10, and to determine that the tooth is carious (carious) when the value of the state coefficient Qt is in the range of 0.1 or more, as seen from fig. 10.

In the present embodiment, a graph of the relationship between the value of the state coefficient Qt and the state of the tooth as illustrated in fig. 10 is stored in the auxiliary storage device 54 of the server 5 as the determination information database D503. This process corresponds to the determination criterion forming step in this embodiment. Then, the value of the state coefficient Qt is calculated from the measurement data of the raman scattered light received from the mobile terminal 3, the state of the tooth is derived from the determination information database D503, and the result is transmitted to the mobile terminal 3 as determination result data. Therefore, the health state of the tooth can be determined and managed at the stage before the tooth becomes a state of caries.

It should be noted that, as shown in equation (2) and fig. 11, the above-described determination algorithm takes into account the wave number shift of about 600cm^-1In particular about 580cm^-1The strongest peak of the hydroxyapatite appeared at and about 560cm^-1The ratio between the shoulders of the tricalcium phosphate association which occurs, whereby the accuracy can be further improved.

[ formula 2]

Thus, according to the present embodiment, the person to be examined can easily know the health state of the teeth in his/her own home. Further, information of a dental hospital to be hospitalized can be obtained based on personal data such as the residence of the subject and the determination result data. Moreover, the reservation processing can be rapidly advanced with the dental hospital to be hospitalized, and the state of the teeth can be efficiently managed.

In the above-described embodiments, an example in which the present invention is applied to the management of the state of teeth is described. However, the subject of health management to which the present invention is applied is not limited to the state of the teeth. Another example of health management using measurement of raman scattered light will be described below.

(management of skin Condition)

When the state of the skin is managed by measuring raman scattered light, for example, the following formula (3) is used.

[ formula 3]

Herein, R is_PFIs I_dAnd I_αThe intensity ratio of (a). And, I_dIs the wave number (cm)^-1) The integrated area intensity of the peak in the band of 1681 to 1682 corresponds to C ═ O stretching motion in the disordered structure (amide I). In addition, I_αIs the wave number (cm)^-1) The integrated area intensity of the peak in the band 1652-1654 corresponds to C ═ O stretching motion in α -helix (amide I)₁And k₂As test conditions, constants depending on the characteristics of the laser and raman spectroscopic device 2 were used.

The age-to-intensity ratio R of the skin provider is shown in FIG. 12_PFA graph of the relationship of (a). In the figure, k₁＝0.77，k₂0.012. Thus, the intensity ratio R is seen_PFAnd age of the skinThe correlation of (c). Therefore, it is possible to provide: the age and R are stored in advance in the auxiliary storage device 54 of the server 5_PFThe judgment information database D503 for the relationship (a) receives the measurement data of raman spectroscopy from the mobile terminal 3, judges the skin age, and transmits the judgment result data to the mobile terminal 3.

[ formula 4]

In addition, BMI and obesity can be managed according to the skin condition. In this case, the following formulas (4) and (5) may be used.

[ formula 5]

Herein, R is_LC1Is (I)_h+o+cp) And (I)₁+I₅) The intensity ratio of (a). R_LC2Is (I)_h+o) And I_lThe intensity ratio of (a). And, I_hIs the wave number (cm)^-1) Integrated area intensity of peak in 2877 to 2879 band corresponding to vs (CH) in lipid in hexagonal state₃). In addition, I_oIs the wave number (cm)^-1) The integrated area intensity of the peak in the frequency band of 2882 to 2888 corresponds to vs (CH) in the orthorhombic lipid₃)。I_cpIs the wave number (cm)^-1) The integrated area intensity of the peak in the 2902-2910 band corresponds to vs (CH) in cholesterol and phospholipids₂) And vs (CH)₃)。k₁、k₂、k₃Is a constant depending on the experimental conditions, and the BMI (BodyMass Index: body Index) is at R_LC1And R_LC2Different physique indexes.

FIG. 13 shows the intensity ratio R_LCGraph of example of BMI versus age of skin providers. From this figure, R_LCAnd there is a strong correlation between BMI and age of the skin provider. Therefore, it is also possible to previously store the data in the auxiliary storage device of the server 5Storing age and R in a storage device 54_LC1、R_LC2The relation between BMI and BMI is the determination information database D503, and the measurement data of raman spectroscopy result and the data of age are received from the mobile terminal 3 to determine BMI and obesity, and the measurement data of raman spectroscopy result and the data of BMI and obesity are received from the mobile terminal 3 to determine skin age.

(management of bone status)

The wave number (cm) measured for healthy bones and osteoporosis bones by raman scattering spectroscopy is shown in fig. 14^-1) The results were statistically summarized as phenylalanine peaks around 1005. As is clear from fig. 14, in the osteoporotic bone, the wave number of the phenylalanine peak was not uniform and the raman scattered light intensity was reduced as compared with the healthy bone.

Therefore, when the bone state is managed by the measurement of raman scattered light, the following equations (6) to (8) can be used, for example.

[ formula 6]

[ formula 7]

[ formula 8]

Here, I₁₀₀₅Is the phenylalanine peak. Phenylalanine has a wide range of known metabolic effects and is also associated with a deficiency in the mineral content of bone. The intensity ratios of equations (6) to (8) can be used for managing the contents of collagen and minerals in the bone.

Therefore, it is also possible to store the contents of collagen and minerals or the risk of osteoporosis and P in the server 5 in advance_c ^r、P_b ^r、Q_c ^rAs a judgmentThe fixed information database D503 receives measurement data of raman spectroscopy from the mobile terminal 3, and determines the contents of collagen and minerals or the risk of osteoporosis.

The bone state can be evaluated by using a combination of at least two or more main components of the mineral components and the biological matrix of the bone. Since the raman spectrum of a bone is characterized by many regions and peaks, the state of the bone can be evaluated by various methods other than the above-described raman spectroscopic measurement.

For example, since the mineral component of a bone is composed of hydroxyapatite, it can be determined by the same method as the determination of enamel of a tooth. Alternatively, the determination of the osteoporosis or osteonecrosis state may be performed based on a decrease in the intensity of a raman peak associated with sphingomyelin, a raman peak associated with phospholipids, or a raman peak associated with lipid filling or viscosity. Fig. 15 shows raman peaks associated with sphingomyelin measured by raman scattering spectroscopy on healthy bones and osteoporotic bones, and the results are statistically summarized. As is clear from fig. 15, in the osteoporotic bone, the wave number of the sphingomyelin peak was increased and the raman scattered light intensity was decreased as compared with the healthy bone.

Description of reference numerals:

1 … … A health management system for use in a health management system,

2 … … Raman spectroscopic device, and a light source,

3 … … A portable terminal, wherein the portable terminal comprises a main body,

4 … … the measurement of the end point,

the 5 … … server is used to make the server,

7 … … hospital terminal.