阅读说明：本技术 一种含三氟苯嘧啶的杀虫组合物 (Insecticidal composition containing trifluoro-benzene pyrimidine ) 是由 葛家成 熊风 司国栋 于 2019-01-17 设计创作，主要内容包括：本发明公开的一种含三氟苯嘧啶的杀虫组合物,有效活性成分由第一活性成分三氟苯嘧啶与第二活性成分虫酰肼或甲氧虫酰肼中的一种组成。第一活性成分与第二活性成分的重量比为1:50-50:1,含量之和为所述组合物总重量的1%-80%。本组合物可制备成农业上允许的各种剂型,优选为水分散粒剂、可湿性粉剂、悬浮剂、水乳剂。该组合物的杀虫效果不是各组分活性的简单叠加,与现有单一制剂相比,除具有显著的杀虫效果外,而且有显著的增效作用,用药量减少,对作物安全性好。(The invention discloses an insecticidal composition containing trifluoro-benzene pyrimidine, and the effective active ingredient is composed of trifluoro-benzene pyrimidine serving as a first active ingredient and tebufenozide or methoxyfenozide serving as a second active ingredient. The weight ratio of the first active ingredient to the second active ingredient is 1:50-50:1, and the sum of the contents is 1% -80% of the total weight of the composition. The composition can be prepared into various agriculturally acceptable formulations, and is preferably water dispersible granules, wettable powder, suspending agents and emulsion in water. The insecticidal effect of the composition is not the simple superposition of the activities of all the components, and compared with the existing single preparation, the composition has the advantages of obvious insecticidal effect, obvious synergistic effect, reduced dosage and good safety to crops.)

1. The insecticidal composition containing the trifluorobenzene pyrimidine is characterized in that a first active ingredient is the trifluorobenzene pyrimidine, and a second active ingredient is one of tebufenozide or methoxyfenozide.

2. The insecticidal composition according to claim 1, wherein the weight ratio of the first active ingredient to the second active ingredient is 1:50 to 50:1, preferably 1:10 to 10: 1.

3. The insecticidal composition according to claim 1, wherein the weight ratio of trifluoro-fluoropyrimidine to tebufenozide is 1: 5-1: 1, and the weight ratio of trifluoro-fluoropyrimidine to methoxyfenozide is 1: 5-2: 1.

4. The insecticidal composition of claim 1, wherein the weight ratio of triflumfluoropyrimidine to tebufenozide is 1:3, and the weight ratio of triflumfluoropyrimidine to methoxyfenozide is 1: 2.

5. An insecticidal composition according to claim 1, wherein the total weight of the active ingredients is 1% to 80%, preferably 10% to 40% of the total weight of the formulation.

6. The insecticidal composition according to claim 5, wherein the total weight of the trifluorobenzene pyrimidine and the tebufenozide is 20%, and the total weight of the trifluorobenzene pyrimidine and the methoxyfenozide is 15%.

7. The insecticidal composition according to claim 1, wherein the insecticidal composition consists of an active ingredient and a pesticide adjuvant.

8. The insecticidal composition as claimed in any one of claims 1 to 4, wherein the insecticidal composition can be prepared into various formulations allowed by pesticides, preferably water dispersible granules, wettable powder, suspending agent and emulsion in water.

9. The insecticidal composition of claim 8, wherein the insecticidal composition is used for controlling rice planthopper, rice stem borer, cabbage beet armyworm.

Technical Field

The invention relates to an insecticidal composition containing trifluoro-benzene pyrimidine and application thereof, the composition consists of trifluoro-benzene pyrimidine serving as a first active ingredient, tebufenozide or methoxyfenozide serving as a second active ingredient and auxiliary ingredients, and belongs to the technical field of compound pesticides.

Background

Trifluoropyrimidine is a novel mesoionic or zwitterionic pesticide developed by DuPont, and is also a novel pyrimidinone compound. The trifluoro-benzene pyrimidine has the main characteristics of high efficiency, lasting effect, low dosage and environmental protection, and is mainly used for preventing and controlling rice planthoppers, leafhoppers and the like. It has different action mechanism with neonicotinoid insecticide and has no adverse effect on pollinating insects.

Tebufenozide is a novel bionic insecticide for promoting the molting of lepidoptera larvae, acts on an insect molting receptor to cause the premature molting of the insect larvae, the early molting and death or the formation of abnormal pupae and abnormal imagoes to cause chemical sterilization.

Methoxyfenozide belongs to a phenylhydrazide insect growth regulator and an ecdysone insecticide, and the main mechanism is to interfere the normal growth and development of insects and inhibit feeding. The methoxyfenozide has strong insecticidal object selectivity, has high selective insecticidal activity on lepidoptera pests, takes contact killing effect as a main part, and has certain systemic effect. The action mechanism of the pesticide is opposite to that of the pesticide for inhibiting molting of pests, the pesticide can be used for preventing and treating the pests in the whole larval stage, and the pesticide is safe to beneficial insects and beneficial mites and is environment-friendly.

The applicant finds that the compound of the trifluoro-benzene pyrimidine with different action mechanisms and the tebufenozide or the methoxyfenozide has the following advantages and beneficial effects: 1. the synergistic effect, the mixing of the preparations with different action mechanisms is beneficial to mutually improving the drug effect; 2. increasing the mode of action on the pests. 3. Delaying the generation of drug resistance of pests. Because the insecticidal action mechanism of the trifluoro-benzene pyrimidine is special, the trifluoro-benzene pyrimidine has no cross resistance with tebufenozide or methoxyfenozide, and the mixed preparation compounded with the trifluoro-benzene pyrimidine can delay the drug resistance of pests.

Disclosure of Invention

The invention aims to provide an agricultural insecticidal composition which has reasonable components, obvious synergistic effect, good insecticidal effect, low medication cost and is safe to crops.

Another object of the present invention is to provide a dosage form of the insecticidal composition containing trifluorobenzene pyrimidine.

The invention also aims to provide application of the composition in preventing and treating lepidoptera and homoptera.

In order to achieve the purpose, the technical scheme of the invention is as follows:

an insecticidal composition containing trifluorobenzene pyrimidine and tebufenozide or methoxyfenozide is characterized in that a first active ingredient is trifluorobenzene pyrimidine, and a second active ingredient is tebufenozide or methoxyfenozide.

The weight ratio of the first active ingredient to the second active ingredient of the composition is 1:50-50:1, and preferably 1: 10-10: 1.

The sum of the contents of the first active ingredient and the second active ingredient of the composition is 1-80%, preferably 10-40%.

The composition consists of an active ingredient and a pesticide auxiliary ingredient.

Further, the auxiliary components of the pesticide preparation comprise a carrier and an auxiliary agent.

Further, the carrier is one, two or three of water, solvent or filler, and the water is preferably deionized water.

Further, the solvent is selected from the group consisting of N, N-dimethylformamide, cyclohexanone, toluene, xylene, dimethyl sulfoxide, methanol, ethanol, trimethylcyclohexanone, N-octylpyrrolidone, ethanolamine, triethanolamine, and isopropylamine. One or more of N-methyl pyrrolidone, propanol, butanol, ethylene glycol, diethylene glycol, ethylene glycol methyl ether, butyl ether, ethanolamine, isopropylamine, ethyl acetate or acetonitrile.

Further, the filler is selected from one or a mixture of more of kaolin, diatomite, bentonite, attapulgite, white carbon black, starch or light calcium carbonate.

Furthermore, the auxiliary agent at least comprises a surfactant, and other functional auxiliary agents such as an antifreezing agent, a thickening agent, a stabilizing agent, a disintegrating agent, a defoaming agent and the like can be added according to different use occasions and requirements.

Further, the surfactant is selected from one or four of an emulsifier, a dispersant, a wetting agent or a penetrant. The surfactant is a single agent or a compound preparation of a common nonionic surfactant or an anionic surfactant.

Further, the other functional auxiliary agents are selected from one or five of antifreeze, thickening agent, stabilizing agent, disintegrating agent or defoaming agent.

Further, the emulsifier is selected from one or more of agricultural milk No. 500 (calcium alkyl benzene sulfonate), OP series phosphate ester (nonylphenol polyoxyethylene ether phosphate ester), No. 600 phosphate ester (phenylphenol polyoxyethylene ether phosphate ester), styrene polyoxyethylene ether ammonium sulfate salt, magnesium salt of alkyl diphenyl ether disulfonate, triethanolamine salt, agricultural milk No. 400 (benzyldimethylphenol polyoxyethylene ether), agricultural milk No. 700 (alkylphenol formaldehyde resin polyoxyethylene ether), Ning milk No. 36 (phenethylphenol formaldehyde resin polyoxyethylene ether), agricultural milk No. 1600 (phenethylphenol polyoxyethylene polyoxypropylene ether), ethylene oxide-propylene oxide block copolymer, OP series (nonylphenol polyoxyethylene ether), BY series (castor oil polyoxyethylene ether), agricultural milk No. 33 (alkylaryl polyoxyethylene polyoxypropylene ether), span series (sorbitan monostearate), Tween series (sorbitan series polyoxyethylene ether) or AEO (fatty alcohol polyoxyethylene ether) A mixture of the components.

Further, the dispersing agent is selected from one or a mixture of a plurality of polycarboxylate, lignosulfonate, alkylphenol polyoxyethylene formaldehyde condensate sulfate, calcium alkylbenzene sulfonate, naphthalene sulfonic acid formaldehyde condensate sodium salt, alkylphenol polyoxyethylene, fatty amine polyoxyethylene, fatty acid polyoxyethylene or glycerol fatty acid ester polyoxyethylene.

Further, the wetting agent is selected from one or a mixture of more of sodium dodecyl sulfate, sodium dodecyl benzene sulfonate, nekal BX, wetting penetrant F, Chinese honeylocust fruit powder, silkworm excrement and soapberry powder.

Further, the penetrating agent is selected from a mixture consisting of one or more of penetrating agent JFC (fatty alcohol-polyoxyethylene ether), penetrating agent T (diisooctyl maleate sulfonate), azone or organic silicon.

Further, the antifreezing agent is a mixture consisting of one or more of ethylene glycol, propylene glycol, glycerol or urea.

Further, the thickening agent is selected from one or more of xanthan gum, polyvinyl alcohol, bentonite, carboxymethyl cellulose or magnesium aluminum silicate.

Further, the stabilizing agent is selected from one or more of epoxidized soybean oil, epichlorohydrin, BHT, ethyl acetate and triphenyl phosphate.

Further, the disintegrating agent is selected from one or more of bentonite, urea, ammonium sulfate, aluminum chloride, low-substituted hydroxypropyl cellulose, lactose, citric acid, succinic acid or sodium bicarbonate.

Further, the defoaming agent is selected from one or a mixture of more of silicone oil, silicone compounds, C10-C20 saturated fatty acid compounds or C8-C10 fatty alcohol compounds.

The above substances are all commercially available.

The insecticidal composition can be used for preventing and controlling lepidoptera and homoptera pests.

Compared with the prior art, the invention has the beneficial effects that: 1. by adopting the compound scheme, the insecticidal composition has obvious synergy on lepidoptera and homoptera pests such as rice planthoppers, rice chilo suppressalis, cabbage spodoptera exigua and the like, and obviously improves the control effect; 2. the dosage and the frequency of medication are reduced, and the prevention and treatment cost is reduced; 3. overcomes the defect of easy generation of resistance after long-term single use, and prolongs the service life of the medicament.

Detailed description of the preferred embodiments

Preparation of the preparation

The preparation method of the water dispersible granule comprises the following steps: adding active ingredients of trifluoro-fluoropyrimidine, tebufenozide or methoxyfenozide into a carrier according to the formula proportion of an embodiment, adding a surfactant and other functional auxiliaries, mixing, performing jet milling, adding 10-25% of water, kneading, granulating, drying and screening to obtain a water dispersible granule product; or spraying water to the pulverized powder in a boiling granulator, granulating, drying, and sieving to obtain the final product. The main equipment comprises a mixer, a jet mill, a kneader, an extrusion granulator, a drying room or a fluidized bed for drying, or a boiling granulator and a sieving machine.

The formula of the water dispersible granule is as follows: 0.1-80% of active ingredient A, 0.1-60% of active ingredient B, 3-12% of dispersing agent, 1-8% of wetting agent, 1-10% of disintegrating agent and the balance of filler.