Feed additive capable of replacing antibiotics to prevent diarrhea of chicks and improve growth and application of feed additive
阅读说明：本技术 替代抗生素预防雏鸡腹泻提高生长性饲料添加剂及其应用 (Feed additive capable of replacing antibiotics to prevent diarrhea of chicks and improve growth and application of feed additive ) 是由 张金勇 于 2020-04-02 设计创作，主要内容包括：本发明涉及一种替代抗生素预防雏鸡腹泻、提高生长性能的饲料添加剂及其应用,由以下成分按重量份数组成：小宗原料20％,大宗原料80％；所述大宗原料为生物发酵饲料,生物发酵饲料预先粉碎过30目筛；本发明饲料添加剂安全无毒副作用,无药物残留,安全可靠,能够调节雏鸡肠道菌群平衡,促进消化吸收,修复小肠绒毛,保护肠道健康,有效预防断雏鸡腹泻、过料的发生,促进雏鸡的生长,从而提高养殖效益。(The invention relates to a feed additive for replacing antibiotics to prevent diarrhea of chicks and improve growth performance and application thereof, wherein the feed additive comprises the following components in parts by weight: 20% of small raw materials and 80% of large raw materials; the bulk raw materials are biological fermentation feeds, and the biological fermentation feeds are pre-crushed and sieved by a 30-mesh sieve; the feed additive is safe, has no toxic or side effect, has no drug residue, is safe and reliable, can adjust the balance of intestinal flora of the chicks, promotes digestion and absorption, repairs intestinal villi, protects the intestinal health, effectively prevents diarrhea and overfeeding of the broilers, promotes the growth of the chicks, and thus improves the breeding benefit.)
1. The feed additive capable of replacing antibiotics to prevent diarrhea and improve growth performance of chicks is characterized by comprising the following components in parts by weight: 20% of small raw materials and 80% of large raw materials;
the bulk raw materials are biological fermentation feeds, and the biological fermentation feeds are pre-crushed and sieved by a 30-mesh sieve;
the formula table of the raw materials of the small heald comprises the following components:
2. The feed additive for preventing diarrhea and improving growth performance of chicks according to claim 1, which replaces antibiotics, is characterized in that: the content of the bacillus licheniformis is 1000 hundred million CFU/g; the content of enterococcus faecalis is 100 hundred million CFU/g; 10 million u/g of protease, 10 million u/g of cellulase and 5 million u/g of mannanase; the sanguinarine content of the macleaya cordata crude extract is more than or equal to 3 percent; the content of tributyrin is more than or equal to 35 percent; the content of montmorillonite is not less than 98%, and is medical grade montmorillonite.
3. The feed additive for preventing diarrhea and improving growth performance of chicks according to claim 1, which replaces antibiotics, is characterized in that: the water content of the biological fermentation feed before fermentation is 34-36%, the biological fermentation feed is placed in a one-way valve fermentation bag, fermented for 8 days in a fermentation chamber at 25-30 ℃, and then dried until the water content is not more than 10%, the viable count reaches 10 hundred million CFU/g, the crude protein is not less than 45%, and the small peptide is not less than 15%.
4. The feed additive for preventing diarrhea and improving growth performance of chicks according to claim 3, which replaces antibiotics, is characterized in that: the raw material eucommia ulmoides leaf chlorogenic acid in the biological fermentation feed is more than or equal to 0.8%.
5. The feed additive for preventing diarrhea and improving growth performance of chicks according to claim 1, 3 or 4, instead of antibiotics, characterized in that: the preparation method of the biological fermentation feed comprises the following steps: 55% of soybean meal, 5% of bran and 40% of eucommia leaves are crushed and mixed, matched with protease, cellulase, pectinase, light calcium carbonate, brown sugar, saccharomyces cerevisiae, lactobacillus plantarum and bacillus licheniformis, water is added to adjust the water content of the materials to be 34-36%, the materials are placed in a one-way valve fermentation bag and are fermented for 8 days in a fermentation chamber at 25-30 ℃, and then the materials are dried until the water content is not more than 10% to obtain the biological fermentation feed. The saccharomyces cerevisiae is 100 hundred million CFU/g, the lactobacillus plantarum is 100 hundred million CFU/g, and the content of the bacillus licheniformis is 1000 hundred million CFU/g. The number of live bacteria in the provided biological fermentation feed reaches 10 hundred million CFU/g, the crude protein is more than or equal to 45 percent, and the small peptide is more than or equal to 15 percent.
6. The application of the feed additive for replacing antibiotics to prevent diarrhea and improve growth performance of chicks is characterized in that: the additive according to claims 1-5 is added to the daily ration of chicks in a proportion of 5-7 kg/t.
Technical Field
The invention belongs to the field of feed additives, and particularly relates to a feed additive for replacing antibiotics to prevent diarrhea of chicks and improve growth performance and application thereof.
Background
The chick body temperature regulating system is imperfect; the growth is rapid, and the metabolism is vigorous; the feather grows fast, the protein demand is high; small stomach volume and weak digestion; the disease resistance is poor. At present, antibiotics are mainly used for health care and treatment in the stage, but long-term and excessive use of antibiotics can cause drug resistance of pathogenic bacteria, and the clinical dosage is larger and the curative effect is worse. Meanwhile, the addition of antibiotics in the feed is prohibited by the country. Therefore, the development of green and safe feed additives which replace antibiotics to prevent diarrhea of the chicks and improve the growth performance is needed.
Disclosure of Invention
The invention aims to provide a feed additive for replacing antibiotics to prevent diarrhea of chicks and improve growth performance and application thereof. The feed additive is safe, free of toxic and side effects, free of drug residues, safe and reliable, and capable of adjusting the balance of intestinal flora of the chicks, promoting digestion and absorption, repairing intestinal villi, protecting intestinal health, effectively preventing diarrhea and overfeeding of the broilers, and promoting the growth of the chicks, so that the breeding benefit is improved.
The invention is realized by adopting the following technical scheme: a feed additive for replacing antibiotics to prevent diarrhea of chicks and improve growth performance comprises the following components in parts by weight: 20% of small raw materials and 80% of large raw materials;
the bulk raw materials are biological fermentation feeds, and the biological fermentation feeds are pre-crushed and sieved by a 30-mesh sieve;
the formula table of the raw materials of the small heald comprises the following components:
further, the content of the bacillus licheniformis is 1000 hundred million CFU/g; the content of enterococcus faecalis is 100 hundred million CFU/g; 10 million u/g of protease, 10 million u/g of cellulase and 5 million u/g of mannanase; the sanguinarine content of the macleaya cordata crude extract is more than or equal to 3 percent; the content of tributyrin is more than or equal to 35 percent; the content of montmorillonite is not less than 98%, and is medical grade montmorillonite.
Furthermore, the water content of the biological fermentation feed before fermentation is 34-36%, the biological fermentation feed is placed in a one-way valve fermentation bag, fermented for 8 days in a fermentation chamber at 25-30 ℃, and then dried until the water content is not more than 10%, the viable count reaches 10 hundred million CFU/g, the crude protein is not less than 45%, and the small peptide is not less than 15%.
Furthermore, the raw material eucommia ulmoides leaf chlorogenic acid in the biological fermentation feed is more than or equal to 0.8%.
Still further, the preparation method of the biological fermentation feed comprises the following steps: 55% of soybean meal, 5% of bran and 40% of eucommia leaves are crushed and mixed, matched with protease, cellulase, pectinase, light calcium carbonate, brown sugar, saccharomyces cerevisiae, lactobacillus plantarum and bacillus licheniformis, water is added to adjust the water content of the materials to be 34-36%, the materials are placed in a one-way valve fermentation bag and are fermented for 8 days in a fermentation chamber at 25-30 ℃, and then the materials are dried until the water content is not more than 10% to obtain the biological fermentation feed. The saccharomyces cerevisiae is 100 hundred million CFU/g, the lactobacillus plantarum is 100 hundred million CFU/g, and the content of the bacillus licheniformis is 1000 hundred million CFU/g. The number of live bacteria in the provided biological fermentation feed reaches 10 hundred million CFU/g, the crude protein is more than or equal to 45 percent, and the small peptide is more than or equal to 15 percent.
The application of the feed additive for replacing antibiotics to prevent diarrhea and improve growth performance of the chicks is characterized in that the additive is added into daily ration of the chicks in a proportion of 5-7 kg/t.
The invention has the beneficial effects that: the feed additive is safe, has no toxic or side effect, has no drug residue, is safe and reliable, can adjust the balance of intestinal flora of the chicks, promotes digestion and absorption, repairs intestinal villi, protects the intestinal health, effectively prevents diarrhea and overfeeding of the broilers, promotes the growth of the chicks, and thus improves the breeding benefit.
Detailed Description
A feed additive for replacing antibiotics to prevent diarrhea of chicks and improve growth performance comprises the following components in parts by weight: 20% of small raw materials and 80% of large raw materials;
the bulk raw materials are biological fermentation feeds, and the biological fermentation feeds are pre-crushed and sieved by a 30-mesh sieve;
table 1 formula table of small heald raw materials
Raw materials
Proportioning
Tributyrin
30
Macleaya cordata crude extract
20
Enterococcus faecalis
2
Bacillus licheniformis
3
Protease enzyme
3
Mannanase
2
Cellulase enzymes
5
Montmorillonite (montmorillonite)
35
Total up to
100
The content of the bacillus licheniformis is 1000 hundred million CFU/g; the content of enterococcus faecalis is 100 hundred million CFU/g; 10 million u/g of protease, 10 million u/g of cellulase and 5 million u/g of mannanase; the sanguinarine content of the macleaya cordata crude extract is more than or equal to 3 percent; the content of tributyrin is more than or equal to 35 percent; the content of montmorillonite is not less than 98%, and is medical grade montmorillonite.
In the additive, the preparation method of the biological fermentation feed comprises the following steps: 55% of soybean meal, 5% of bran and 40% of eucommia leaves are crushed and mixed, matched with protease, cellulase, pectinase, light calcium carbonate, brown sugar, saccharomyces cerevisiae, lactobacillus plantarum and bacillus licheniformis, water is added to adjust the water content of the materials to be 34-36%, the materials are placed in a one-way valve fermentation bag and are fermented for 8 days in a fermentation chamber at 25-30 ℃, and then the materials are dried until the water content is not more than 10% to obtain the biological fermentation feed. The saccharomyces cerevisiae is 100 hundred million CFU/g, the lactobacillus plantarum is 100 hundred million CFU/g, and the content of the bacillus licheniformis is 1000 hundred million CFU/g. The number of live bacteria in the provided biological fermentation feed reaches 10 hundred million CFU/g, the crude protein is more than or equal to 45 percent, and the small peptide is more than or equal to 15 percent.
The preparation method of the feed additive comprises the following steps:
premixing tributyrin, macleaya cordata crude extract, enterococcus faecalis, bacillus licheniformis, protease, mannase, cellulase and montmorillonite, uniformly mixing with the biological fermentation feed, and vacuum packaging.
The component characteristics of each component are as follows:
glycerol tributyrate: the energy is supplied quickly, the repair of villi and mucosa of the small intestine is promoted, and the recovery of the function of the damaged intestinal tract is accelerated.
Macleaya cordata extract: antiinflammatory, energy loss preventing, optimal production performance maintaining, intestinal flora regulating, harmful bacteria inhibiting, intestinal health improving, and disease resistance enhancing effects
B, bacillus licheniformis: can produce antibacterial active substances such as bacteriocin and the like, and regulate the balance of intestinal flora. Meanwhile, digestive enzymes such as protease and the like can be produced by metabolism, and the digestibility of the chick feed is improved.
Enterococcus faecalis: can improve the immune response of the energy animal and improve the antibody level; can form a lactic acid bacteria barrier on the intestinal mucosa to shield external pathogenic bacteria and toxin;
protease, mannanase, cellulase: promoting the digestion of protein and cellulose, and degrading the anti-nutritional factors in the feed.
Montmorillonite: has the functions of adsorbing and fixing mycotoxin and other pathogenic bacteria. Can increase the amount of digestive tract mucosa and activate blood coagulation factors, thereby protecting the digestive tract mucosa from being damaged.
Biological fermentation feed: contains probiotics, small peptides and nutrient substances after being pre-digested. The palatability of the feed can be improved, the utilization rate of the feed is improved, and the cost of the feed is saved. The small peptide can improve the immunity of the organism and improve the health level of the chicks. In addition, the eucommia leaves added in the fermented feed are rich in chlorogenic acid, eucommia flavone, eucommia polysaccharide, aucubin and pinoresinol diglucoside, and have the effects of inhibiting bacteria, killing bacteria, protecting liver and protecting kidney. The functional components are released after fermentation, and the effect is better.
The product of the invention has the following functions: according to the physiological characteristics of the chicks, a plurality of beneficial bacteria, digestive enzyme, tributyrin, macleaya cordata crude extract, biological fermentation feed and the like are scientifically compounded to protect, repair intestinal tracts, sterilize and inhibit bacteria, so that the compound feed has the effects of improving the health of the intestinal tracts, repairing the intestinal tracts, preventing and treating diarrhea and overfeeding, improving the growth performance, and is non-toxic, harmless, residue-free, green, safe and pollution-free.
Examples of animals: this example is an application test example of the feed additive.
The feeding test was carried out in 1-2 months in 2020 on a chicken farm in Huqiu county, Liuan City, Anhui, province. 1500 feathers of healthy Aivina meat cocks which just come out of the shell are selected and randomly divided into 5 groups, each group has 3 repetitions, and each repetition has 100 feathers. The control group is fed with basic diet, the test 1 group is added with 50g/t of aureomycin in the basic diet, and the tests 2-4 groups are respectively fed with test diet added with 0.5%, 0.6% and 0.7% of the additive in the basic diet. Test period 21 d. The method is characterized by adopting on-net flat breeding, brooding with an infrared lamp, free ingestion and drinking of water, 24 hours of illumination, 35 ℃ in week 1, 32-30 ℃ in week 2 and 30-27 ℃ in week 3. The feeding conditions in each column are basically consistent. Immunization was carried out according to the conventional immunization procedure in chicken farms.
TABLE 2 Effect of additives on chick Productivity, survival and diarrhea Rate
From the above table, the average daily gain and average daily feed intake of the test groups are both significantly higher than those of the control group, which indicates that the additive has the effect of increasing the daily gain similar to that of aureomycin, and the test groups 3 and 4 are both significantly higher than that of the test group 1, which indicates that the effect of the high-dose additive group is better than that of the single aureomycin group. The activity rate of the test composition is obviously higher than that of the control group, and the difference between the additive group and the aureomycin group is not obvious. The diarrhea rate of the test group is lower than that of the control group, and the difference between the additive group and the aureomycin group does not obviously indicate that the additive has the same effect of preventing diarrhea as aureomycin. In conclusion, the additive with the content of 0.5-0.7% is added into the young bird feed, so that the daily gain and survival rate of young birds can be obviously improved, the feed conversion ratio and diarrhea rate are reduced, and the feed intake trend is improved.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof.