阅读说明：本技术 油酰基-溶血磷脂酰肌醇(油酰基-lpi)的合成衍生物及其用途 (Synthetic derivatives of oleoyl-lysophosphatidylinositol (oleoyl-LPI) and uses thereof ) 是由 M·法拉什 M·马西 P·V·辛普森 于 2018-08-31 设计创作，主要内容包括：本发明涉及油酰基-溶血磷脂酰肌醇(油酰基-LPI)及其新的合成衍生物和用途,并且涉及包含这类化合物的药物组合物。本发明提供了糖调节性激素如胰高血糖素样肽-1(GLP-1)的活化剂和/或向上调节剂,更具体是GPR119的激动剂、部分激动剂和逆拮抗剂或者GLP-1活性和/或合成和/或分泌的活化剂,包含它们的药物组合物,它们在治疗糖尿病、肥胖和其它代谢疾病中的用途。(The present invention relates to oleoyl-lysophosphatidylinositol (oleoyl-LPI) and novel synthetic derivatives and uses thereof, and to pharmaceutical compositions comprising such compounds. The present invention provides activators and/or upregulators of sugar-regulated sex hormones, such as glucagon-like peptide-1 (GLP-1), more particularly agonists, partial agonists and inverse antagonists of GPR119, or activators of GLP-1 activity and/or synthesis and/or secretion, pharmaceutical compositions containing them, and their use in the treatment of diabetes, obesity and other metabolic disorders.)