Application of plant small molecules in improving skin elasticity and preparing beauty skin care products

文档序号:1369206 发布日期:2020-08-14 浏览:14次 中文

阅读说明:本技术 一种植物小分子在提高皮肤弹性和制备美容护肤品方面的用途 (Application of plant small molecules in improving skin elasticity and preparing beauty skin care products ) 是由 王曦 其他发明人请求不公开姓名 于 2020-06-13 设计创作,主要内容包括:本发明公开了一种植物小分子在提高皮肤弹性和制备美容护肤品方面的用途。真皮成纤维细胞是真皮层中最主要的细胞,它与自身分泌的胶原蛋白、弹性蛋白和其他细胞外基质成分共同构成了真皮的主体。大量研究证明,成纤维细胞因其特有的生物学变化,在皮肤衰老的过程中扮演着重要角色。如果真皮成纤维细胞的增殖活力降低,就会导致皮肤更新缓慢,修复能力变差,日渐老化;如果真皮成纤维细胞中的弹性蛋白含量减少,就会导致皮肤弹性降低。本发明研究发现,16-羰基-24-乙酰泽泻醇A可以促进真皮成纤维细胞增殖,促进皮肤更新,提高皮肤修复能力;提高弹性蛋白的含量,提高皮肤弹性。(The invention discloses application of plant micromolecules in the aspects of improving skin elasticity and preparing beauty skin care products. Dermal fibroblasts are the most prominent cells in the dermis layer and constitute the main body of the dermis together with self-secreted collagen, elastin and other extracellular matrix components. Numerous studies have demonstrated that fibroblasts, due to their characteristic biological changes, play an important role in the process of skin aging. If the proliferation activity of dermal fibroblasts is reduced, the skin is slowly renewed, the repair capability is poor, and the skin is gradually aged; if the elastin content in dermal fibroblasts is reduced, a reduction in skin elasticity results. The research of the invention finds that the 16-carbonyl-24-acetyl alisol A can promote the proliferation of dermal fibroblasts, promote the renewal of skin and improve the skin repair capacity; increasing elastin content and improving skin elasticity.)

1. An application of a plant small molecule in improving skin elasticity is provided, wherein the plant small molecule is 16-carbonyl-24-acetyl alisol A.

2.16-carbonyl-24-acetyl alisol A is used for improving the skin repair capability.

3. A skin caring product for improving skin elasticity and skin repairing ability contains 16-carbonyl-24-acetyl alisol A.

4. The beauty skin care product according to claim 3, which is a facial cleanser and has the following formula.

Class of component Mass fraction of the components Myristic acid isopropyl ester 4% Lanolin 3% Sorbitan fatty acid ester 2.5% Coconut diethanol amine 2.5% Xanthan gum 0.08% Coconut oil thickening foaming agent 0.02% Phenoxyethanol 0.5% Essence 0.03% 16-carbonyl-24-acetyl alisol A 0.3% Deionized water Make up to 100%

5. The beauty skin care product according to claim 3, which is a face cream and has the following formula.

6. The beauty skin care product according to claim 3, which is a mask and has the following formula.

Components Mass fraction Glycerol 9% Konjak gum glucomannan 4.5% Olive fruit oil 1.2% Coconut diethanol amine 1.2% Sorbitan fatty acid ester 1.5% Xanthan gum 0.1% Hyaluronic acid sodium salt 0.08% Essence 0.02% 16-carbonyl-24-acetyl alisol A 0.6% Deionized water Make up to 100%

Technical Field

The invention belongs to the field of cosmetics, relates to improvement of skin elasticity, and particularly relates to application of plant small molecules in improvement of skin elasticity and preparation of a beauty skin care product.

Background

With age, various tissues and organs including the skin are gradually aged. Skin aging is mainly manifested by thinning, slow renewal, appearance of wrinkles, dryness and roughness, pigmentation, skin laxity, and reduced elasticity.

Dermal fibroblasts are the most prominent cells in the dermis layer and constitute the main body of the dermis together with self-secreted collagen, elastin and other extracellular matrix components. Numerous studies have demonstrated that fibroblasts, due to their characteristic biological changes, play an important role in the process of skin aging.

The concrete expression is as follows: the proliferation activity of dermal fibroblasts is reduced, so that the skin is slowly renewed, the skin repair capacity is poor, and the skin is gradually aged; a decrease in the amount of elastin in dermal fibroblasts, a decrease in skin elasticity; and so on.

Chendi and the like have studied the anti-aging effect of glacier water and snow tea extracts on normal human dermal fibroblasts and potential mechanisms thereof, and as a result, found that glacier water and snow tea extracts can improve the proliferation activity and energy metabolism level of human dermal fibroblasts, promote the expression effect of hyaluronic acid and elastin, and improve skin elasticity (experimental research on the delay of human dermal fibroblast aging by glacier water and snow tea extracts, natural product research and development, vol. 30 of 2018).

16-carbonyl-24-acetyl alisol A is a natural chemical component existing in alisma orientale, and no research on the aspect of improving skin elasticity is available.

Disclosure of Invention

The invention aims to overcome the defects of the prior art and provides the application of a plant micromolecule in improving the skin elasticity and preparing a beauty skin care product, wherein the plant micromolecule is 16-carbonyl-24-acetyl alisol A.

The purpose of the invention is realized by the following technical scheme:

an application of a plant small molecule in improving skin elasticity is provided, wherein the plant small molecule is 16-carbonyl-24-acetyl alisol A.

Application of 16-carbonyl-24-acetyl alisol A in improving skin repair capability.

A skin caring product for improving skin elasticity and skin repairing ability contains 16-carbonyl-24-acetyl alisol A.

Further, the beauty skin care product is facial cleanser, and the formula is as follows.

Further, the beauty skin care product is a face cream, and the formula is as follows.

Class of component Mass fraction of the components
Glycerol 9%
Butanediol 4.5%
Olive fruit oil 2%
1, 2-hexanediol 0.6%
Sorbitan fatty acid ester 0.8%
Aminomethyl propanol 0.5%
Hyaluronic acid sodium salt 0.08%
Xanthan gum 0.03%
Guar gum 0.03%
Essence 0.03%
16-carbonyl-24-acetyl alisol A 0.5%
Ethylenediaminetetraacetic acid disodium salt 0.05%
Deionized water Make up to 100%

Further, the beauty skin care product is a facial mask, and the formula is as follows.

Has the advantages that:

dermal fibroblasts are the most prominent cells in the dermis layer and constitute the main body of the dermis together with self-secreted collagen, elastin and other extracellular matrix components. Numerous studies have demonstrated that fibroblasts, due to their characteristic biological changes, play an important role in the process of skin aging. If the proliferation activity of dermal fibroblasts is reduced, the skin is slowly renewed, the repair capability is poor, and the skin is gradually aged; if the elastin content in dermal fibroblasts is reduced, a reduction in skin elasticity results. The research of the invention finds that the 16-carbonyl-24-acetyl alisol A can promote the proliferation of dermal fibroblasts, promote the renewal of skin and improve the skin repair capacity; increasing elastin content and improving skin elasticity.

Drawings

FIG. 1 shows the Western Blot results; the result shows that 16-carbonyl-24-acetyl alisol A with different concentrations can effectively improve the expression quantity of elastin in human dermal fibroblast HDF, and the effect of improving the expression quantity is more obvious when the concentration is higher.

Detailed Description

The following examples are intended to illustrate the essential technical content of the present invention, and the scope of the present invention should not be limited by the specific general details described in the following examples.

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