Antibacterial mask and preparation method thereof

文档序号:1399553 发布日期:2020-03-06 浏览:22次 中文

阅读说明:本技术 一种抑菌面膜及其制备方法 (Antibacterial mask and preparation method thereof ) 是由 朱晓波 于 2019-12-06 设计创作,主要内容包括:本发明属于面膜技术领域,公开了一种抑菌面膜,包括面膜纸和附着在所述面膜纸上的溶液,所述溶液包括以体积份数计算的透明质酸15-30份、卡波姆5-20份、利多卡因3-15份、生育酚乙酸酯1-3份和生理盐水40-60份。本发明还公开了一种抑菌面膜的制备方法,通过原料的混合、浸泡、震荡得到成品面膜。本发明的面膜,利用透明质酸和卡波姆较为温和的性质,将其作为软化角质层和药物的载体,利多卡因用于抑菌。果酸用于软化角质层,以便于利多卡因的更好的渗透。生育酚乙酸酯起到了抗氧化的作用。生理盐水作为各个组分的溶剂。本发明的制备方法制备流程较少,易于操作。通过浸泡、震荡等步骤,使得溶液更加均匀的分布于面膜上,便于使用。(The invention belongs to the technical field of facial masks, and discloses an antibacterial facial mask which comprises facial mask paper and a solution attached to the facial mask paper, wherein the solution comprises 15-30 parts by volume of hyaluronic acid, 5-20 parts by volume of carbomer, 3-15 parts by volume of lidocaine, 1-3 parts by volume of tocopheryl acetate and 40-60 parts by volume of physiological saline. The invention also discloses a preparation method of the antibacterial mask, and the finished product mask is obtained by mixing, soaking and shaking the raw materials. The facial mask disclosed by the invention utilizes the milder properties of hyaluronic acid and carbomer, the hyaluronic acid and carbomer are used as carriers for softening horny layers and medicines, and lidocaine is used for inhibiting bacteria. The fruit acid serves to soften the stratum corneum for better penetration of lidocaine. The tocopherol acetate plays a role in resisting oxidation. Physiological saline serves as a solvent for each component. The preparation method provided by the invention has fewer preparation processes and is easy to operate. Through steps such as soaking, vibrate for solution more evenly distributes on the facial mask, convenient to use.)

1. An antibacterial mask is characterized in that: the facial mask comprises facial mask paper and a solution attached to the facial mask paper, wherein the solution comprises 15-30 parts by volume of hyaluronic acid, 5-20 parts by volume of carbomer, 3-15 parts by volume of lidocaine, 1-3 parts by volume of tocopherol acetate and 40-60 parts by volume of physiological saline.

2. A bacteriostatic mask according to claim 1, wherein: the solution comprises 20 parts of hyaluronic acid, 15 parts of carbomer, 10 parts of lidocaine, 2 parts of tocopherol acetate and 50 parts of normal saline in parts by volume.

3. A bacteriostatic mask according to claim 1, wherein: the solution also comprises 3-6 parts of fruit acid calculated by volume parts.

4. A bacteriostatic mask according to claim 2, wherein: the solution also includes 4 parts by volume of fruit acid.

5. A bacteriostatic mask according to any one of claims 1-4, wherein: the facial mask paper comprises: any one of 100% cotton facial mask paper, silk facial mask paper and biological fiber facial mask paper.

6. A preparation method of the antibacterial mask is characterized by comprising the following steps: the method comprises the following steps:

s1, weighing hyaluronic acid, carbomer, lidocaine, tocopheryl acetate, normal saline and tartaric acid in corresponding volume parts according to a formula;

s2, adding hyaluronic acid and carbomer into a container, uniformly stirring, adding lidocaine, normal saline and tocopheryl acetate into the container, and continuously and uniformly stirring to obtain a solution;

s3, flatly laying the facial mask paper into a facial mask container, pouring the solution prepared in the step S2 into the facial mask container, shaking for 1 minute, and soaking for 1 hour to obtain the finished facial mask.

7. The preparation method of the antibacterial mask according to claim 6, characterized by comprising the following steps: in the step S2, hyaluronic acid and carbomer are added into the container, and stirred uniformly, then lidocaine, normal saline and tartaric acid are added into the container, and stirred uniformly to obtain the solution.

8. The preparation method of the antibacterial mask according to claim 6, characterized by comprising the following steps: the container in the step S2 is an aseptic stainless steel container; throughout the process of performing the above step S2, the temperature is controlled at 36 degrees celsius.

9. The preparation method of the antibacterial mask according to claim 6, characterized by comprising the following steps: throughout the process of performing the above step S3, the pressure is maintained at 2 atmospheres.

Technical Field

The invention belongs to the technical field of facial masks, and particularly relates to an antibacterial facial mask and a preparation method thereof.

Background

The facial mask is a category of skin care products, is a carrier of the beauty care products, and is applied on the face for beauty functions such as moisturizing, whitening, anti-aging, grease balancing and the like. The mask is a short-term skin packaging measure, so that if other things which should not exist on the skin, such as suppuration and the like, some unexpected effects can be generated on the skin, before the mask is applied, proper cleaning is carried out to remove dead skin scab, and the key problem parts are treated properly under the guidance of doctors. Otherwise, the effect of the mask application can not be achieved, and adverse reaction is generated. At present, before the operation of peeling the face, ointment with a sterilization effect is often used for smearing the whole face, after smearing is finished, the face is covered by a plastic film, after a period of time, the plastic film is detached, the face is wiped cleanly, the operation is more complicated, smearing is not uniform easily, the film covering only covers the part, and the use is inconvenient.

Disclosure of Invention

In order to solve the problems in the prior art, the invention aims to provide an antibacterial mask convenient to use and a preparation method thereof.

The technical scheme adopted by the invention is as follows:

an antibacterial mask comprises mask paper and a solution attached to the mask paper, wherein the solution comprises 15-30 parts by volume of hyaluronic acid, 5-20 parts by volume of carbomer, 3-15 parts by volume of lidocaine, 1-3 parts by volume of tocopherol acetate and 40-60 parts by volume of physiological saline.

Further, the solution comprises 20 parts of hyaluronic acid, 15 parts of carbomer, 10 parts of lidocaine, 2 parts of tocopheryl acetate and 50 parts of normal saline in parts by volume.

Further, the solution also comprises 3-6 parts of fruit acid calculated by volume parts.

Further, the solution also comprises 4 parts of fruit acid calculated by volume parts.

Further, the facial mask paper is: any one of 100% cotton facial mask paper, silk facial mask paper and biological fiber facial mask paper.

Hyaluronic acid is a disaccharide unit hyaluronic acid composed of D-glucuronic acid and N-acetylglucosamine, also called uronic acid and hyaluronic acid, and its basic structure is a large polysaccharide composed of two disaccharide units D-glucuronic acid and N-acetylglucosamine. Unlike other mucopolysaccharides, it contains no sulfur. Its hyaluronic molecule can carry over 500 times of water, is the best moisture-keeping component recognized at present, and is widely applied to maintenance products and cosmetics. Hyaluronic acid is an acidic mucopolysaccharide. Hyaluronic acid exhibits various important physiological functions in the body with its unique molecular structure and physicochemical properties, such as lubricating joints, regulating permeability of blood vessel walls, regulating proteins, regulating diffusion and operation of aqueous electrolytes, promoting wound healing, and the like.

More importantly, hyaluronic acid has a special water retention effect, is the best natural moisture retention substance discovered at present in nature, and is called an ideal natural moisture retention factor, such as: a2% pure hyaluronic acid aqueous solution can firmly maintain 98% of water. Hyaluronic acid is a multifunctional matrix, and hyaluronic acid (hyaluronic acid) HA is widely distributed in various parts of the human body. Wherein the skin also contains a significant amount of hyaluronic acid. The skin aging process of human beings also changes with the content and metabolism of hyaluronic acid, it can improve skin nutrition metabolism, make skin tender and smooth, remove wrinkle, increase elasticity, prevent aging, and is good transdermal absorption enhancer while keeping moisture. The nutrient can be used together with other nutrient components to achieve the more ideal effect of promoting nutrient absorption.

Hyaluronic acid has biochemical drugs with high clinical value, and is widely applied to various ophthalmic surgeries, such as crystal implantation, corneal transplantation, anti-glaucoma surgeries and the like. It can also be used for treating arthritis and promoting wound healing. The skin care cosmetic has unique skin protection effect, can keep skin moist, smooth, fine, tender and elastic, and has the effects of preventing wrinkles, resisting wrinkles, beautifying, protecting health and recovering physiological functions of the skin.

Carbomer is a high molecular polymer of acrylic acid bonded allyl sucrose or pentaerythritol allyl ether. Carbomer is a very important rheology regulator, neutralized carbomer is an excellent gel matrix, has important applications of thickening, suspending and the like, has simple process and good stability, and is widely applied to emulsion, cream and gel. Carbomers are generally neutralized to a salt, which causes the curled molecules to thicken as a result of the opening of electrical repulsion, and sodium hydroxide and triethanolamine are common neutralizing agents, which are responsible for the sensitivity of carbomers to ions. Carbomer molecules act as carboxyl donors and bind to one or more hydroxyl groups to form hydrogen bonds for thickening, and this neutralization requires time, and the commonly used hydroxyl donors are nonionic surfactants, polyols, and the like. Carbomers produce highly effective thickening at very low levels (0.25-0.5% of conventional levels) to produce emulsions, creams, gels and transdermal preparations of a wide range of viscosities and varying rheological properties. Carbomer has the following characteristics: the surfactant is effective at a concentration of 0.1-0.5%, and replaces the traditional surfactant with the dosage of 3-7%; without limitation by HLB and PlT; any liquid oil can be emulsified at room temperature, such as by melting waxes during the manufacturing process, emulsifiable waxes; the functions of wetting, dispersing, adhering and the like of the surfactant are fully exerted; can be made into stable emulsion; the emulsion can not be re-emulsified when being re-wetted, and the waterproof emulsion without the film forming agent is easy to prepare; the high oil phase can be dissolved in water to form (o/w) emulsion; can be made into moistening cream, lotion, face cleaning product, sunscreen product, alcohol-free perfume, essence hair conditioner (with luster enhancing effect and easy combing), and hand cleanser; low consistency sprayable emulsions and clear microemulsions, and the like.

Lidocaine is a local anesthetic and antiarrhythmic drug that is a derivative of ***e, but has no components of ***e that produce hallucinations and addiction. The hydrochloride of the lidocaine is white crystalline powder, is easy to dissolve in water, has toxicity equivalent to that of procaine, has stronger and lasting local anesthesia effect and good surface penetration, and can be injected and used for surface anesthesia. Lidocaine is a very good local anaesthetic, generally acting after one to three minutes of administration, with the effect remaining for one to three hours. Can be used for treating oral ulcer. The lidocaine also has an antibacterial effect, and has a remarkable antibacterial effect under a clinical common dosage (0.5% -1%), and the antibacterial effect tends to be enhanced along with the increase of the concentration. Lidocaine also has antiviral and antiinflammatory effects.

Tocopherol acetate is a chemical substance, easily soluble in chloroform, diethyl ether, acetone and vegetable oil, soluble in alcohol, and insoluble in water. Has good heat resistance, can be oxidized when being exposed to light, has dark color and belongs to vitamin E derivatives. The vitamin E can prevent cell membrane and unsaturated fatty acid in cell from being oxidized easily in the metabolism process of organism, thereby protecting the integrity of cell membrane and preventing aging, and maintaining the normal function of reproductive organ. Vitamin E has strong reducibility, and can be used as antioxidant. Can be used as antioxidant in vivo, and can eliminate free radicals in vivo and reduce the damage of ultraviolet rays to human body. Because vitamin E used as an additive of medicines, nourishments and cosmetics for skin care, hair care and the like has stronger reducibility, the vitamin E has the functions of resisting oxidation and preventing aging in the metabolism process of a human body, and can keep the normal functions of reproductive organs.

Physiological saline, also known as sterile physiological salt, refers to a sodium chloride solution with osmotic pressure substantially equal to that of animal or human plasma, which is commonly used in physiological experiments or clinical practice. Physiological saline can be used as a fluid replacement (without reducing or increasing the sodium ion concentration in normal human bodies) and other medical purposes, and is also commonly used for culturing living tissues and cells in vitro. Is the concentration of the liquid environment in which the human cells are located. Can avoid cell rupture, has the same osmotic pressure as the outside of the cell, and can not cause the cell to dehydrate or excessively absorb water, so that the liquid is used in many places needing liquid in various medical operations, and the concentration of the liquid environment in which the human cells live is high. In order to correct dehydration and acidosis, different liquids are often mixed into a mixed solution according to a certain proportion for clinical application.

Fruit acids are various organic acids extracted from fruits and are effective components existing in various natural fruits or yogurt. Contains gluconic acid, malic acid, citrus acid, lactic acid, etc., and is called fruit acid because most of them are extracted from fruits. Among them, glycolic acid extracted from sugarcane is most widely used. Fruit acids can be distinguished according to their molecular structure: 37 kinds of glycolic acid, lactic acid, malic acid, tartaric acid, citric acid, mandelic acid and the like, however, in the medical beauty field, the most commonly applied components are glycolic acid and lactic acid. Glycolic acid, also known as saccharate and glycolic acid, was first extracted from sugar cane and is one of the most widely used fruit acid products. Glycolic acid has the smallest molecular weight of the fruit acids (76) and therefore penetrates the top layer of the skin most easily, and the absorption effect is most pronounced, being the fruit acid most commonly used for skin resurfacing. Lactic acid, which has the second smallest molecular weight of fruit acids (90), is widely used to improve dry skin and keratosis because of its high moisture retention and natural components that do not irritate human skin. At high concentrations, tartaric acid, followed by glycolic acid and lactic acid, is the most rapidly loosening and peeling skin. For cell renewal, lactic acid is the most effective, followed by glycolic acid. Very low concentrations of fruit acids have only a moisturizing effect. When the concentration is slightly increased, the skin care product has the function of removing cutin, can destroy the connection between cutin cells and promote the metabolism of the skin. At higher concentrations, its destructive power is greater, the effect reaches dermal tissue, and it can be used for chemical skin-changing. Generally, the effect is more pronounced at higher concentrations, but the chances of side effects are relatively increased.

Effect of different concentrations of fruit acid:

1. low concentration of fruit acid (less than 10%): the fruit acid can reduce the coagulation force among epidermal corneocytes, remove aged corneous substances, improve roughness and darkness, and condition skin.

2. Medium concentration tartaric acid (10% -30%): the tartaric acid has the effects of reaching the dermal tissue and having good effects on whelk, black spot lightening and wrinkle smoothing.

3. High concentration fruit acid (more than 30%): has quite strong penetrability, can peel off aged cutin once, and accelerate the effects of removing spots and wrinkles. However, high concentrations of fruit acids are skin-resurgence properties and it is best to seek a professional physician for treatment.

The function of the fruit acid is as follows: the tartaric acid preparation can weaken the adhesion of keratinocyte, and peel off the stratum corneum deposited on skin to make skin bright and moist. One of the reasons for the formation of common acne is that the adhesion of keratin cells at the infundibulum folliculorum is increased, and the keratinized matter is accumulated to cause the blockage of the opening of a hair follicle, so that sebaceous glands cannot smoothly discharge sebum, thereby producing comedones of whiteheads, comedones of blackheads, inflammatory papules, pustules or cysts; high concentration of fruit acid for separating epidermis from dermis in external use of the high concentration fruit acid preparation can separate epidermis from dermis, which is exfoliating agent (peeling). The fruit acid preparation has mild stripping effect, and can prevent abnormal pigment and scar after healing. The fruit acid is natural organic acid, has no toxic or side effect on the whole body in normal dosage, is a nutrient substance beneficial to the skin and has good nourishing effect on the skin; the tartaric acid moisturizing skin tartaric acid preparation can enable the cuticle to fall off and expand the capillary vessels of the dermal superficial layer, so that the skin looks ruddy and bright; the fruit acid is a humectant of the skin, and can ensure that the skin layer cells contain sufficient water, so that the skin is glossy and soft; the fruit acid preparation can relieve skin aging, such as skin thinning, dermal papilla connective tissue thickening, wrinkle, pigmented spot and dry skin due to long-term sunlight exposure. The external use fruit acid preparation can thicken epidermis, thin connective tissue of dermal papilla layer, reduce color failure, moisten skin, and relieve wrinkles and aging; the external use fruit acid preparation for improving skin texture has the effect of degranulation of mast cells in the superficial dermis. The medium released by the mast cell degranulation stimulates fibroblasts in the dermis, so that the quantity of the cavity fibrils and the elastic fibers is increased, and the skin is full and elastic again. The fruit acid can dilate blood capillary and improve skin blood circulation, thereby improving skin texture; the fruit juice contains fruit acid, which can accelerate the dissolution of the antibacterial drug, not only reduce the drug effect, but also can generate harmful intermediate products and generate toxic and side effects.

According to the formula, the hyaluronic acid and carbomer are used as carriers for softening cuticles and medicines by utilizing the milder properties of the hyaluronic acid and the carbomer, and the lidocaine is used for inhibiting bacteria. The fruit acid serves to soften the stratum corneum for better penetration of lidocaine. The tocopherol acetate plays a role in resisting oxidation. Physiological saline serves as a solvent for each component.

A preparation method of the antibacterial mask comprises the following steps:

s1, weighing hyaluronic acid, carbomer, lidocaine, tocopheryl acetate, normal saline and tartaric acid in corresponding volume parts according to a formula;

s2, adding hyaluronic acid and carbomer into a container, uniformly stirring, adding lidocaine, normal saline and tocopheryl acetate into the container, and continuously and uniformly stirring to obtain a solution;

s3, flatly laying the facial mask paper into a facial mask container, pouring the solution prepared in the step S2 into the facial mask container, shaking for 1 minute, and soaking for 1 hour to obtain the finished facial mask.

In the step S2, hyaluronic acid and carbomer are added into the container, and stirred uniformly, then lidocaine, normal saline and tartaric acid are added into the container, and stirred uniformly to obtain the solution.

The container in the step S2 is an aseptic stainless steel container; throughout the process of performing the above step S2, the temperature is controlled at 36 degrees celsius.

Throughout the process of performing the above step S3, the pressure is maintained at 2 atmospheres.

The invention has the beneficial effects that:

the facial mask disclosed by the invention utilizes the milder properties of hyaluronic acid and carbomer, the hyaluronic acid and carbomer are used as carriers for softening horny layers and medicines, and lidocaine is used for inhibiting bacteria. The fruit acid serves to soften the stratum corneum for better penetration of lidocaine. The tocopherol acetate plays a role in resisting oxidation. Physiological saline serves as a solvent for each component. The preparation method provided by the invention has fewer preparation processes and is easy to operate. Through steps such as soaking, vibrate for solution more evenly distributes on the facial mask, convenient to use.

Detailed Description

The present invention is further illustrated below with reference to specific examples.

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