阅读说明：本技术 一种含丙硫菌唑和乳酸链球菌素的组合杀菌物 (Composition bactericide containing prothioconazole and nisin ) 是由 李思源 谢远芳 代新红 李渊泉 朱植银 周蕲 李扬 肖永良 于 2019-12-13 设计创作，主要内容包括：本发明公开了一种含有丙硫菌唑和乳酸链球菌素的杀菌组合物,包含有效成分丙硫菌唑和乳酸链球菌素,丙硫菌唑和乳酸链球菌素的质量比为1-80∶1-80。该杀菌组合物可应用于防治果树,蔬菜,禾谷类作物的细菌病害病害,具有明显的协同增效作用,延缓了病原菌的抗药性,持效期长,减少用药次数和用药量,降低了使用成本。本发明所述的组合杀菌物可用于防治小麦白粉病、纹枯病、枯萎病、叶斑病等病害,效果显著。(The invention discloses a sterilization composition containing prothioconazole and nisin, which comprises the effective components of prothioconazole and nisin, wherein the mass ratio of prothioconazole to nisin is 1-80: 1-80. The bactericidal composition can be applied to control of bacterial diseases of fruit trees, vegetables and cereal crops, has obvious synergistic effect, delays the drug resistance of pathogenic bacteria, has long duration, reduces the drug use times and the drug use amount, and reduces the use cost. The composite bactericide can be used for preventing and treating diseases such as wheat powdery mildew, banded sclerotial blight, fusarium wilt, leaf spot and the like, and has a remarkable effect.)

1. The bactericidal composition containing prothioconazole and nisin is characterized by comprising the active ingredients of prothioconazole and nisin, wherein the mass ratio of prothioconazole to nisin is 1-80: 1-80.

2. The bactericidal composition of claim 1, wherein the mass ratio of prothioconazole to nisin is 1-5: 1-5.

3. The bactericidal composition according to any one of claims 1 to 2, wherein prothioconazole and nisin are used as active ingredients and are formulated into any formulation which is agriculturally acceptable together with an auxiliary pesticide, a filler or a solvent.

4. The germicidal composition of claim 3, wherein: the weight percentage of the prothioconazole and the nisin is 2-80%.

5. The bactericidal composition according to claim 1, which is used for preventing and treating wheat powdery mildew, banded sclerotial blight, fusarium wilt or leaf spot.

6. Use of a fungicidal composition according to claim 5, characterized in that: the dosage of the composition is 100-150g a.i./hm²。

Technical Field

The invention relates to the field of agricultural disease control, in particular to a composite bactericide containing prothioconazole and nisin.

Background

Prothioconazole, the mechanism of action of prothioconazole, is to inhibit demethylation at position 14 of lanosterol or 24-methylene dihydro MI, precursors of sterols in fungi, i.e. demethylation inhibitors (DMIs). Not only has good systemic activity, excellent protection, treatment and eradication activity, but also has long lasting period. Through a large number of field efficacy tests, the results show that the prothioconazole has good safety to crops, good effects of preventing and treating diseases and obvious yield increase, and compared with triazole bactericides, the prothioconazole has broad-spectrum bactericidal activity.

Prothioconazole is mainly used for controlling a plurality of diseases of cereal crops such as wheat, barley, rape, peanut, rice, bean crops and the like. Almost has good control effect on all wheat diseases, such as powdery mildew, banded sclerotial blight, leaf spot, rust disease, sclerotinia, net spot, leaf streak and the like of wheat and barley. Can also prevent and control soil-borne diseases of the rape and the peanut, such as sclerotinia, and main leaf surface diseases, such as gray mold, black spot, brown spot, black shank, sclerotinia, rust and the like. The dosage used is usually 200g a.i./hm²At this dose, the activity is superior to or equal to that of conventional bactericides such as epoxiconazole, tebuconazole, cyprodinil and the like.

Nisin (Nisin), also known as Nisin or transliteration as nixin, is a polypeptide substance produced by streptococcus lactis, consists of 34 amino acid residues, has a molecular weight of about 3500Da, and is widely applied to the food industry as a food preservative because Nisin can inhibit most gram-positive bacteria and has a strong inhibitory effect on spores of bacillus, after eating, Nisin can be rapidly hydrolyzed into amino acids under the physiological pH condition of a human body and the action of α -chymotrypsin, so that the Nisin does not change the normal flora in the intestinal tract of the human body and generate resistance problems like other antibiotics, and does not generate cross resistance with other antibiotics, and the Nisin is a natural food preservative with high efficiency, no toxicity, safety and no side effect.

In recent years, fungal diseases on crops are in a remarkable rising trend, the difficulty of disease control is increasing, the prohibition of antibiotics puts new requirements on selection of disease control medicaments, and the need of green, safe and efficient control medicaments is urgently needed.

At present, the difficulty of preventing and controlling diseases is getting bigger and bigger, the change of a planting structure, the increase of pathogenic bacteria resistance, the prevention and control effect of a single agent is unsatisfactory, and the prevention and control of plant diseases face huge challenges.

Disclosure of Invention

The object of the invention is that: provides a synergistic bactericidal composition containing prothioconazole and nisin with outstanding control effect and low dosage. The inventor finds that the nisin has better inhibition effect on various plant diseases through a large number of growth tests. The composition disclosed by the invention is discovered through a compound screening experiment, has obvious effects on wheat powdery mildew, banded sclerotial blight, blight and leaf spot, has an effect obviously superior to that of a single agent, and can reduce the using amount of pesticides.

In order to achieve the purpose, the invention adopts the technical scheme that:

the bactericidal composition contains the active ingredients of prothioconazole and nisin. Wherein the mass ratio of the prothioconazole to the nisin is 1-80: 1-80, and the preferred mass ratio is 1-5: 1-5.

The prothioconazole and the nisin are used as main active ingredients and necessary auxiliary ingredients such as pesticide auxiliary agents, fillers or solvents and the like to prepare any formulation allowed in pesticides.

Wherein the weight percentage of the prothioconazole and the nisin in the preparation is 2-80%.

The bactericidal composition provided by the invention can be used for preventing and treating wheat powdery mildew, banded sclerotial blight, fusarium wilt and leaf spot.

Further, the dosage of the bactericidal composition is 100-150g a.i./hm²。

Compared with the prior art, the invention has the beneficial effects that:

1. the bactericidal composition containing prothioconazole and nisin has obvious synergy;

2. the bactericidal composition containing prothioconazole and nisin has the advantages of small dosage and long lasting period;

3. the sterilization composition containing prothioconazole and nisin is not easy to generate resistance;

4. the bactericidal composition containing prothioconazole and nisin is green and safe, and is an excellent medicament for producing pollution-free fruits and vegetables.

Detailed Description

The technical scheme and the technical effect of the invention are further explained by combining specific embodiments.

The percentages stated in the present invention are percentages by weight, but the embodiments of the invention are not limited to the ranges stated in the examples.

The experiment adopts a method combining indoor toxicity measurement and field test. Firstly, the indoor toxicity is measured, a proper proportion is screened, and then the field test is carried out on the basis.