阅读说明：本技术 加热模组 (Heating module ) 是由 曹震廷 王兆松 郭小建 于 2020-04-26 设计创作，主要内容包括：本发明公开了一种加热模组,包括：加热头,该加热头的侧壁上设有侧吸磁铁组件,加热头的底部设有底吸磁铁组件；侧吸磁铁驱动机构,其用来单独驱动侧吸磁铁组件的侧吸磁铁来回移动；底吸磁铁驱动机构,其用来单独驱动底吸磁铁组件的底吸磁铁来回移动；以及控制器,其用来分别控制侧吸磁铁驱动机构和底吸磁铁驱动机构工作,使得侧吸磁铁与底吸磁铁分别对应处于工作位或非工作位。可以达到减少加热模组,避免模组切换引起的运动定位误差和加热模组间的温度测量系统误差,提高仪器稳定性和降低成本的目的。(The invention discloses a heating module, comprising: the side wall of the heating head is provided with a side-attraction magnet assembly, and the bottom of the heating head is provided with a bottom-attraction magnet assembly; a side attraction magnet driving mechanism for driving the side attraction magnets of the side attraction magnet assembly to move back and forth independently; the bottom attracting magnet driving mechanism is used for independently driving the bottom attracting magnet of the bottom attracting magnet assembly to move back and forth; and the controller is used for respectively controlling the side attraction magnet driving mechanism and the bottom attraction magnet driving mechanism to work, so that the side attraction magnet and the bottom attraction magnet are respectively and correspondingly positioned at a working position or a non-working position. Can reach and reduce the heating module, avoid the module to switch the temperature measurement system error between motion positioning error and the heating module group that arouses, improve instrument stability and reduce cost's purpose.)

1. A heating module, comprising:

the side wall of the heating head is provided with a side attraction magnet assembly, and the bottom of the heating head is provided with a bottom attraction magnet assembly;

a side attraction magnet driving mechanism for driving the side attraction magnets of the side attraction magnet assembly to move back and forth independently;

the bottom attracting magnet driving mechanism is used for independently driving the bottom attracting magnet of the bottom attracting magnet assembly to move back and forth; and

and the controller is used for respectively controlling the side attraction magnet driving mechanism and the bottom attraction magnet driving mechanism to work, so that the side attraction magnet and the bottom attraction magnet are respectively and correspondingly positioned at a working position or a non-working position.

2. The heating module of claim 1, wherein the side-attracting magnet assembly comprises:

the side attraction magnet guide cylinder is arranged on the side wall of the heating head, and the side attraction magnet is arranged in the side attraction magnet guide cylinder in a sliding manner;

and a side-attraction magnet return spring disposed in the side-attraction magnet guide cylinder to drive the side-attraction magnet to move along the side-attraction magnet guide cylinder toward the heating head.

3. The heating module of claim 2, wherein the bottom-attracting magnet assembly comprises:

the bottom attracting magnet guide cylinder is arranged at the bottom of the heating head, and the bottom attracting magnet is arranged in the bottom attracting magnet guide cylinder in a sliding manner;

and the bottom attraction magnet reset spring is arranged in the bottom attraction magnet guide cylinder and is used for driving the bottom attraction magnet to move towards the heating head along the bottom attraction magnet guide cylinder.

4. The heating module of claim 3, wherein the side-attracting magnet guide cylinder and the bottom-attracting magnet guide cylinder are integrally formed with the heating tip.

5. The heating module of claim 4, wherein the side-attracting magnet guide cylinder is disposed obliquely.

6. The heating module as claimed in claim 5, wherein the side-attracting magnet driving mechanism comprises a side-attracting magnet wire rope, a side-attracting magnet wire rope driving cam, a side-attracting magnet wire rope driving motor, a side-attracting magnet wire rope sheave and a first wire rope fixing seat, one end of the side-attracting magnet wire rope is fixedly connected with the first wire rope fixing seat, the other end of the side-attracting magnet wire rope passes through the side-attracting magnet wire rope driving cam and the side-attracting magnet wire rope sheave and is fixedly connected with the side-attracting magnet, and the side-attracting magnet wire rope driving motor is used for driving the side-attracting magnet wire rope driving cam to rotate so as to pull the side-attracting magnet to move back and forth.

7. The heating module as claimed in claim 6, wherein the bottom-attracting magnet driving mechanism comprises a bottom-attracting magnet wire rope, a bottom-attracting magnet wire rope driving cam, a bottom-attracting magnet wire rope driving motor, a bottom-attracting magnet wire rope sheave and a second wire rope fixing seat, one end of the bottom-attracting magnet wire rope is fixedly connected with the second wire rope fixing seat, the other end of the bottom-attracting magnet wire rope passes through the bottom-attracting magnet wire rope driving cam and the bottom-attracting magnet wire rope sheave and is fixedly connected with the bottom-attracting magnet, and the bottom-attracting magnet wire rope driving motor is used for driving the bottom-attracting magnet wire rope driving cam to rotate so as to pull the bottom-attracting magnet to move back and forth.

8. The heating module of claim 1, wherein the heating head is disposed on a module support having a platform on which the side-attraction magnet drive mechanism and the bottom-attraction magnet drive mechanism are disposed.

9. The heating module of claim 8, wherein the module support further comprises a chassis, the platform and the chassis are connected by a resilient column to form a frame structure, and a peltier device is disposed on the platform for heating the heating tip.

Technical Field

The invention relates to NGS library preparation, in particular to a heating module.

Background

In the existing heating module for NGS library preparation, the heating heads can only be made into 3 types aiming at the bottom attraction magnet and the side attraction magnet, namely only the bottom attraction magnet and only the side attraction magnet are arranged, and no magnet is arranged.

However, the position of the magnet of the existing heating module is fixed, and at least 2 corresponding heating modules must be manufactured to complete the warehouse building process. When the reaction hole needs the heating head of the corresponding magnet, the corresponding heating module is moved to the position of the reaction hole by means of the moving module. The movement mechanism is complex, the occupied space is large, and the cost is high.

Disclosure of Invention

The invention aims to provide a heating module, which integrates a bottom attraction magnet and a side attraction magnet on a heating head and can be respectively and independently controlled to be in a working position and a non-working position, so that the aims of reducing the heating module, avoiding the movement positioning error caused by module switching and the temperature measurement system error between heating modules, improving the instrument stability and reducing the cost can be achieved.

To achieve the above object, the present invention provides a heating module, comprising: the side wall of the heating head is provided with a side-attraction magnet assembly, and the bottom of the heating head is provided with a bottom-attraction magnet assembly; a side attraction magnet driving mechanism for driving the side attraction magnets of the side attraction magnet assembly to move back and forth independently; the bottom attracting magnet driving mechanism is used for independently driving the bottom attracting magnet of the bottom attracting magnet assembly to move back and forth; and the controller is used for respectively controlling the side attraction magnet driving mechanism and the bottom attraction magnet driving mechanism to work, so that the side attraction magnet and the bottom attraction magnet are respectively and correspondingly positioned at a working position or a non-working position.

Alternatively or preferably, the side-attracting magnet assembly comprises: the side attraction magnet guide cylinder is arranged on the side wall of the heating head, and the side attraction magnet is arranged in the side attraction magnet guide cylinder in a sliding manner; and a side-attraction magnet return spring disposed in the side-attraction magnet guide cylinder for driving the side-attraction magnet to move along the side-attraction magnet guide cylinder toward the heating head.

Alternatively or preferably, the bottom suction magnet assembly comprises: the bottom attraction magnet guide cylinder is arranged at the bottom of the heating head, and the bottom attraction magnet is arranged in the bottom attraction magnet guide cylinder in a sliding manner; and the bottom attraction magnet reset spring is arranged in the bottom attraction magnet guide cylinder and is used for driving the bottom attraction magnet to move towards the heating head along the bottom attraction magnet guide cylinder.

Alternatively or preferably, the side-attraction magnet guide cylinder and the bottom-attraction magnet guide cylinder are integrally formed with the heating tip.

Alternatively or preferably, the side-attracting magnet guide cylinder is obliquely arranged.

Optionally or preferably, the side-attraction magnet driving mechanism includes a side-attraction magnet steel wire rope, a side-attraction magnet steel wire rope driving cam, a side-attraction magnet steel wire rope driving motor, a side-attraction magnet steel wire rope sheave and a first steel wire rope fixing seat, one end of the side-attraction magnet steel wire rope is fixedly connected with the first steel wire rope fixing seat, the other end of the side-attraction magnet steel wire rope passes through the side-attraction magnet steel wire rope driving cam and the side-attraction magnet steel wire rope sheave and then is fixedly connected with the side-attraction magnet, and the side-attraction magnet steel wire rope driving motor is used for driving the side-attraction magnet steel wire rope driving cam to rotate so as to pull the side-attraction magnet to move back and forth.

Optionally or preferably, the bottom-attracting magnet driving mechanism comprises a bottom-attracting magnet steel wire rope, a bottom-attracting magnet steel wire rope driving cam, a bottom-attracting magnet steel wire rope driving motor, a bottom-attracting magnet steel wire rope sheave and a second steel wire rope fixing seat, one end of the bottom-attracting magnet steel wire rope is fixedly connected with the second steel wire rope fixing seat, the other end of the bottom-attracting magnet steel wire rope passes through the bottom-attracting magnet steel wire rope driving cam and the bottom-attracting magnet steel wire rope sheave and then is fixedly connected with the bottom-attracting magnet, and the bottom-attracting magnet steel wire rope driving motor is used for driving the bottom-attracting magnet steel wire rope driving cam to rotate so as to pull the bottom-attracting magnet to move back and forth.

Alternatively or preferably, the heating head is disposed on a modular support having a platform on which the side-attraction magnet drive mechanism and the bottom-attraction magnet drive mechanism are disposed.

Optionally or preferably, the module support further comprises a chassis, the platform and the chassis are connected into a frame structure through an elastic upright post, and a peltier patch is laid on the platform and used for heating the heating head.

The technical scheme of the invention has the following beneficial effects: the bottom attraction magnet and the side attraction magnet are integrated on one heating head and can be independently controlled to be in working and non-working positions respectively. The library preparation process does not need to switch the heating module, and can achieve the purposes of reducing the heating module, avoiding the motion and positioning errors caused by module switching, reducing the debugging difficulty, improving the instrument stability and reducing the cost.

Drawings

Fig. 1 is a schematic structural diagram of a heating module according to an embodiment of the present invention;

FIG. 2 is a schematic view of another structure of a heating module according to an embodiment of the present invention;

FIG. 3 is a partial block diagram of a heating module according to an embodiment of the present invention;

FIG. 4 is a partial block diagram of a heating module according to an embodiment of the present invention;

fig. 5 is a schematic view of a driving structure of a side-attraction magnet of the heating module according to an embodiment of the present invention;

FIG. 6 is a schematic diagram of a driving structure of a bottom-attracting magnet of a heating module according to an embodiment of the present invention;

FIG. 7 is a schematic structural diagram of a motor-driven cam of the heating module according to an embodiment of the present invention;

FIG. 8 is a schematic view of the angular position of the cam in the working position (cable relaxed) of the side-attracted magnets provided by embodiments of the present invention;

FIG. 9 is a schematic view of the angular position of the cam when the side-attraction magnet is in the rest position (wire rope tightened) in accordance with an embodiment of the present invention;

FIG. 10 is a schematic view of the angular position of the cam with the bottom-attracting magnet in the operating position (wire rope relaxed) in accordance with an embodiment of the present invention;

fig. 11 is a schematic view of the angular position of the cam when the bottom-attracting magnet is in the non-operating position (wire rope is tightened) according to the embodiment of the invention.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of describing the present invention and simplifying the description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.

The terms "mounted," "connected," and "coupled" are to be construed broadly and may, for example, be fixedly coupled, detachably coupled, or integrally coupled; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the creation of the present invention can be understood by those of ordinary skill in the art through specific situations.

The present invention will be described in further detail with reference to specific examples, but the embodiments of the present invention are not limited thereto.

As shown in fig. 1 to 4, a heating module according to an embodiment of the present invention includes a heating head 1, and it is critical that a side-attraction magnet assembly 17 is disposed on a side wall of the heating head 1, and a bottom-attraction magnet assembly 16 is disposed at a bottom of the heating head 1. The side attraction magnet driving mechanism is used for driving the side attraction magnet of the side attraction magnet assembly 17 to move back and forth independently, the bottom attraction magnet driving mechanism is used for driving the bottom attraction magnet of the bottom attraction magnet assembly 16 to move back and forth independently, and the controller is used for controlling the side attraction magnet driving mechanism and the bottom attraction magnet driving mechanism to work respectively so that the side attraction magnet and the bottom attraction magnet are located at a working position or a non-working position correspondingly respectively.

As a preferred embodiment, the side-attraction magnet assembly 17 includes the following structure:

1. and a side attraction magnet guide cylinder which is arranged on the side wall of the heating head 1, wherein the side attraction magnet is arranged in the side attraction magnet guide cylinder in a sliding way.

2. And a side-attraction magnet return spring 14 provided in the side-attraction magnet guide cylinder to drive the side-attraction magnet to move along the side-attraction magnet guide cylinder toward the heating head 1.

As a preferred embodiment, the bottom suction magnet assembly 16 includes the following structure:

1. and the bottom attraction magnet guide cylinder is arranged at the bottom of the heating head 1, and the bottom attraction magnet is arranged in the bottom attraction magnet guide cylinder in a sliding manner.

2. And a bottom-attracting magnet return spring 15 disposed in the bottom-attracting magnet guide cylinder for driving the bottom-attracting magnet to move toward the heating head 1 along the bottom-attracting magnet guide cylinder.

In a preferred embodiment, the side-attraction magnet guide cylinder and the bottom-attraction magnet guide cylinder are integrally formed with the heating head 1.

In a preferred embodiment, the side-attraction magnet guide cylinder is provided obliquely.

As a preferred embodiment, the side-attraction magnet driving mechanism includes a side-attraction magnet wire rope 10, a side-attraction magnet wire rope driving cam, a side-attraction magnet wire rope driving motor, a side-attraction magnet wire rope sheave 20 and a first wire rope fixing seat, one end of the side-attraction magnet wire rope 10 is fixedly connected with the first wire rope fixing seat, the other end of the side-attraction magnet wire rope 10 passes through the side-attraction magnet wire rope driving cam and the side-attraction magnet wire rope sheave 20 and then is fixedly connected with the side-attraction magnet, and the side-attraction magnet wire rope driving motor is used for driving the side-attraction magnet wire rope 10 to drive the cam to rotate and pull the side-attraction magnet to move back and forth.

As a preferred embodiment, the bottom-attracting magnet driving mechanism includes a bottom-attracting magnet wire rope 9, a bottom-attracting magnet wire rope driving cam, a bottom-attracting magnet wire rope driving motor 6, a bottom-attracting magnet wire rope sheave 20 and a second wire rope fixing seat, one end of the bottom-attracting magnet wire rope 9 is fixedly connected with the second wire rope fixing seat, the other end of the bottom-attracting magnet wire rope 9 passes through the bottom-attracting magnet wire rope driving cam and the bottom-attracting magnet wire rope sheave 20 and then is fixedly connected with the bottom-attracting magnet, and the bottom-attracting magnet wire rope driving motor 6 is used for driving the bottom-attracting magnet wire rope 9 to drive the cam to rotate and then pull the bottom-attracting magnet to move back and forth.

As a preferred embodiment, the heating head 1 is provided on a module holder having a platform on which a side-attraction magnet driving mechanism and a bottom-attraction magnet driving mechanism are arranged.

In a preferred embodiment, the module frame further comprises a chassis, the platform and the chassis are connected to form a frame structure through elastic columns, and a peltier 19 is laid on the platform for heating the heating head 1.

Specifically, as shown in fig. 5 and 6, and fig. 8 to 11, the heating head 1 has two holes (see fig. 4) for mounting the bottom-attracting magnet and the side-attracting magnet, respectively. The two magnets are respectively attached to the magnet adapter 18. One end of the magnet adapter 18 is connected to the magnet and the other end is connected to a flexible wire rope. A spring 12 is arranged on the magnet adapter 18, the other end of the flexible steel wire rope is fixed on the steel wire rope fixing seat, and a plurality of guide grooved wheels 20 and cams are arranged between the magnet and the steel wire rope fixing seat. When the cam rotates to a certain angle, the flexible steel wire rope is loosened, the magnet can reach the working position under the action of the spring 12, when the cam rotates to another angle, the steel wire rope is tensioned, the magnet is pulled back to the non-working position, and the cam is driven by the motor (see fig. 7, fig. 7 shows the installation mode of the motor-driven cam, and the driving modes of the motors of the bottom attraction magnet and the side attraction magnet are consistent).

It should be noted that the side-attraction magnet driving mechanism or the bottom-attraction magnet driving mechanism may directly use a micro motor or a driving device with similar functions to directly drive the magnet, instead of the driving motor, the cam and the wire rope system in this case.

In summary, the heating head 1 of the present embodiment integrates the bottom-attracting magnet and the side-attracting magnet, and the bottom-attracting magnet and the side-attracting magnet can be switched arbitrarily. The flexible steel wire rope is adopted as a transmission mechanism for the switching action of the magnets, the cam mode is adopted as a driving mechanism of the steel wire rope, the number of heating modules can be reduced, the movement and positioning errors caused by module switching can be avoided, the stability of an instrument is improved, the manufacturing cost is reduced, and the debugging difficulty is reduced

In the present embodiment, there is another embodiment of the magnet driving mechanism in which the magnet is directly driven by a member having a linear motion capability, such as an electromagnet, a micro motor, or an air cylinder. The wire rope may be driven by a member having a linear motion capability such as a tension electromagnet, a linear micro motor, or a cylinder, or may be driven by a member having a circular motion capability such as a motor or a rotary cylinder.

Unless defined otherwise, technical or scientific terms used herein shall have the ordinary meaning as understood by one of ordinary skill in the art to which this invention belongs. The use of "first," "second," and similar terms in the description and claims of this patent does not denote any order, quantity, or importance, but rather the terms are used to distinguish one element from another. Also, the use of the terms "a" or "an" and the like do not denote a limitation of quantity, but rather denote the presence of at least one. The terms "connected" or "coupled" and the like are not restricted to physical or mechanical connections, but may include electrical connections, whether direct or indirect.

The above description is only exemplary of the present invention and should not be taken as limiting the invention, as any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.