阅读说明：本技术 一种魔芋葡甘聚糖除螨虫帖及其制备方法 (Konjac glucomannan acarid-removing patch and preparation method thereof ) 是由 庞杰 姜静怡 王唯佳 徐晓薇 陈晓涵 童彩玲 李源钊 郑君滢 陈钰 陈泳诗 郑盛 于 2019-11-15 设计创作，主要内容包括：本发明涉及一种魔芋葡甘聚糖除螨虫帖及其制备方法。魔芋葡甘聚糖除螨虫帖的制备方法,包括魔芋葡甘聚糖胶粘液的配制、过滤、魔芋葡甘聚糖/壳聚糖纳米纤维膜的制备、除螨虫帖的制备。本发明的魔芋葡甘聚糖除螨虫帖,以魔芋葡甘聚糖/壳聚糖纳米纤维膜为载体,并辅以螨虫引诱剂及其他助剂,能够有效清除被褥、沙发中的螨虫。该除螨虫帖具有优良的粘合性,采用物理除螨方式,对人体无害。用魔芋葡甘聚糖作为除螨虫帖的主材料,与塑料板相比,其载药效果更好、除螨效力高,可长效保持被褥的清洁卫生。魔芋葡甘聚糖除螨虫帖可完全生物降解、环保低碳,并且取材方便、价格低廉、生产工艺简单。(The invention relates to a konjac glucomannan acarid-removing patch and a preparation method thereof. The preparation method of the konjac glucomannan acarid-removing patch comprises the steps of preparing konjac glucomannan adhesive liquid, filtering, preparing a konjac glucomannan/chitosan nanofiber membrane and preparing the acarid-removing patch. The konjak glucomannan acarid removing patch takes the konjak glucomannan/chitosan nano fiber membrane as a carrier, is supplemented with the acarid attractant and other auxiliary agents, and can effectively remove acarids in bedding and sofas. The mite-killing patch has excellent adhesiveness, adopts a physical mite-killing mode, and is harmless to human bodies. Compared with a plastic plate, the konjac glucomannan serving as a main material of the acarid removing patch has better drug loading effect and high acarid removing effect, and can keep the cleanness and sanitation of the bedding for a long time. The konjac glucomannan acarid-removing patch can be completely biodegraded, is environment-friendly and low-carbon, and has the advantages of convenient material acquisition, low price and simple production process.)

1. A preparation method of a konjac glucomannan acarid-removing patch is characterized by comprising the following preparation steps:

preparing konjac glucomannan adhesive liquid: prepared according to the mass portion, 0.12 to 0.15 portion of rosin resin, 0.35 to 0.45 portion of polyvinyl alcohol, 0.03 to 0.06 portion of microcrystalline wax, 0.04 to 0.12 portion of terpene resin and 0.12 to 0.16 portion of phosphite ester are taken, and are sequentially added into 94 to 100 portions of water under the conditions of 1500r/min and 85 to 95 ℃, stirred for 6 to 7 hours and then the pH value is adjusted to 7 to 11; then adding 1-2 parts of konjac glucomannan, stirring for 4-5h at 1500r/min and 85-95 ℃ to obtain konjac glucomannan adhesive liquid for later use;

and (3) filtering: filtering the konjac glucomannan adhesive liquid prepared in the step (1) by using a filter screen with the diameter of 1mm, wherein the filtrate is the konjac glucomannan adhesive;

preparing a konjac glucomannan/chitosan nanofiber membrane: taking 0.6-0.8 part of konjac glucomannan and 0.4-0.6 part of chitosan, adding into 99 parts of deionized water in a 50 ℃ water bath while stirring, wherein the stirring speed is 400r/min, and the stirring time is 0.5-1.5 h; then, placing the konjac glucomannan/chitosan nano-fiber membrane in a vacuum drying oven at 50 ℃ for vacuumizing for 5-15min, and preparing the konjac glucomannan/chitosan nano-fiber membrane by using ES series electrostatic spinning equipment;

preparing the acarid removing plaster: mixing 10-20 parts of konjac glucomannan adhesive in the step (2), 40-60 parts of mite attractant and food coloring agent respectively, adding 500 parts of deionized water of 300 and stirring uniformly to form liquid medicine; placing the liquid medicine in a centrifuge, centrifuging and degassing for 30-40min at 3000r/min of 2000-; uniformly coating a pest sticking agent on the dried medicine-carrying konjac glucomannan/chitosan nano fiber membrane, packaging by adopting cotton cloth, slitting and rolling to prepare the acarid removing patch.

2. The method for preparing the konjac glucomannan acarid-removing patch as claimed in claim 1, wherein the pH value is adjusted in step (1) by using 1mol/L NaOH.

3. The method for preparing a konjac glucomannan acarid-removing card according to claim 1, wherein the ES series electrostatic spinning equipment is used for preparing the konjac glucomannan/chitosan nanofiber membrane in the step (3), and the parameters of the ES series electrostatic spinning equipment are as follows: voltage 15KV, receiving distance 10cm, injection speed 0.15cm/min, temperature 45 deg.C, and needle diameter 0.6 cm.

4. A konjac glucomannan acarid-repellent patch prepared by any one of the methods of claims 1-3.

Technical Field

The invention relates to a deinsectization card and a preparation method thereof, in particular to a konjac glucomannan acarid-removing card and a preparation method thereof.

Background

The mites belong to a class of small animals of the class of the subclass Guangdong-web of the class of the arthropoda, and have mouthpieces at the front ends thereof and diversified feeding habits. Currently, mites are found in the world in a variety of 50000, second only to insects. The mites are closely related to the health of people, such as spider mites, chiggers, scabies, dust mites and pyemotes, which can bite people to suck blood and damage the skin, cause acne rosacea or demodex, anaphylaxis, uromite, pulmonary mite, intestinal mite and scabies, and seriously harm the health of people. The invasion of mites into the skin can cause local foreign body reaction, resulting in local inflammatory diseases, such as hair lipid organ blockage, stimulation of cuticle hyperplasia, hair follicle expansion, large pore, hair follicle nutrient deficiency, hair loss and the like. In addition, the mites absorb nutrients supplied to hair roots, so that the roots of hair become thin, the roots shake, and alopecia starts, which causes dandruff, head itching, scalp disorders, coarse hair, and alopecia. Thus, mite cleaning is particularly important.

The most common mite cleaning method in the market at present mainly comprises a drug mite removing and mite removing instrument. The medicament mite killing belongs to chemical mite killing, can effectively kill mites, but medicament residues on the surface of an object can cause harm to a human body. The mite adhesive force is ultra-strong, most of the mites sucked by the mite removing instrument are cotton wool and fabrics, the operation is complicated, and the mites cannot be eradicated fundamentally. In order to improve the living hygiene level of people, a mite removing patch which has a simple structure and is convenient to use and can effectively prevent and treat mites is needed.

The invention patent with application number 201410028290.0 discloses an anti-mite polyester fiber and a preparation method thereof (application date: 2014.01.22), and the anti-mite polyester fiber is prepared, contains 1-5% of anti-mite powder and has a good anti-mite effect. The acaricide or the anti-mite agent is added into the slices before spinning for blending melt spinning, so that the anti-mite functional components are uniformly dispersed in the fiber, and the water washing resistance of the anti-mite fiber is effectively improved. However, the preparation process of the anti-acarid polyester fiber is complex, the anti-acarid polyester fiber is not suitable for large-scale production, and the acaricide may cause harm to human health.

The patent with application No. 201721772499.3, "a multifunctional mite removing bag for removing mites" (application date: 2017.12.18), prepared a multifunctional mite removing bag for removing mites. This remove mite bag is bag column structure, is equipped with sealing device at the top opening part, evenly is equipped with the polylith heating plate in the inboard and the bottom that remove the mite bag, can control the subregion heating of heating plate through outside temperature control system, as long as put into removing the mite bag with article, can utilize the high temperature to kill the mite in the article. The mite removing bag can display the internal temperature in real time and adjust the temperature according to the requirement, has a simple structure, is easy to operate, and has large limitation. The mite removing bag can only remove mites on objects with limited sizes, cannot be applied to beds, sofas and the like, and can damage the surfaces of the objects due to high-temperature mite removal, so that the mites in the objects cannot be thoroughly killed.

The 'mite removing patch' of application No. 201621246014.2 (application date: 2016.11.04) prepared a mite removing patch. The mite killing patch comprises a plastic plate, a hole is formed in the middle of the plastic plate, a mite killing luring bag is arranged on the hole, pest sticking glue is coated on two sides of the plastic plate, and net cloth is respectively arranged on two sides of the plastic plate, so that the mite killing patch is simple in structure and can observe and kill mites to the maximum extent. But the plastic plate is not comfortable enough, has low adhesion degree, is inconvenient to use and has low bioavailability.

With the development of economy, the quality of life of people is continuously improved, and the requirements on the living and sanitary level are gradually improved. In order to meet the health requirements of people, a mite removing patch which is safer and more portable than a traditional mite removing device is urgently needed. The invention adopts the konjac glucomannan as the raw material, and utilizes the high viscosity characteristic to prepare the green environment-friendly acarid-removing patch which has good adhesiveness, high strength, low cost, simple manufacturing process, no harm to human body and degradability. In addition, the konjac glucomannan/chitosan nanofiber membrane improves the phenomenon of low adhesion degree, and solves many safety problems while showing excellent material properties.

Disclosure of Invention

The invention aims to provide a konjac glucomannan acarid-removing patch and a preparation method thereof, which aim to overcome the defects of the existing product.

In order to achieve the purpose, the invention adopts the following technical scheme.

The invention relates to a preparation method of a konjac glucomannan acarid-removing patch, which is characterized by comprising the following preparation steps:

(1) preparing konjac glucomannan adhesive liquid: prepared according to the mass portion, 0.12 to 0.15 portion of rosin resin, 0.35 to 0.45 portion of polyvinyl alcohol, 0.03 to 0.06 portion of microcrystalline wax, 0.04 to 0.12 portion of terpene resin and 0.12 to 0.16 portion of phosphite ester are taken, and are sequentially added into 94 to 100 portions of water under the conditions of 1500r/min and 85 to 95 ℃, stirred for 6 to 7 hours, and then the pH value is adjusted to 7 to 11 by 1mol/L NaOH; then adding 1-2 parts of konjac glucomannan, stirring for 4-5h at 1500r/min and 85-95 ℃ to obtain konjac glucomannan adhesive liquid for later use;

(2) and (3) filtering: filtering the konjac glucomannan adhesive liquid prepared in the step (1) by using a filter screen with the diameter of 1mm, wherein the filtrate is the konjac glucomannan adhesive;

(3) preparing a konjac glucomannan/chitosan nanofiber membrane: taking 0.6-0.8 part of konjac glucomannan and 0.4-0.6 part of chitosan, adding into 99 parts of deionized water in a 50 ℃ water bath while stirring, wherein the stirring speed is 400r/min, and the stirring time is 0.5-1.5 h; then, placing the konjac glucomannan/chitosan nano-fiber membrane in a vacuum drying oven at 50 ℃ for vacuumizing for 5-15min, and preparing the konjac glucomannan/chitosan nano-fiber membrane by using ES series electrostatic spinning equipment; the parameters of the ES series electrostatic spinning equipment are as follows: the voltage is 15KV, the receiving distance is 10cm, the injection speed is 0.15cm/min, the temperature is 45 ℃, and the needle diameter is 0.6 cm;

(4) preparing the acarid removing plaster: mixing 10-20 parts of konjac glucomannan adhesive in the step (2), 40-60 parts of mite attractant and food coloring agent respectively, adding 500 parts of deionized water of 300 and stirring uniformly to form liquid medicine; placing the liquid medicine in a centrifuge, centrifuging and degassing for 30-40min at 3000r/min of 2000-; uniformly coating a pest sticking agent on the dried medicine-carrying konjac glucomannan/chitosan nano fiber membrane, packaging by adopting cotton cloth, slitting and rolling to prepare the konjac glucomannan mite-killing patch.

The mite-killing patch disclosed by the invention takes konjac glucomannan/chitosan nanofiber membrane as a carrier and is supplemented with a mite attractant and other auxiliaries, so that mites in bedding and sofas can be effectively removed. The mite-killing patch has excellent adhesiveness, adopts a physical mite-killing mode, and is harmless to human bodies. Compared with a plastic plate, the konjac glucomannan serving as a main material of the acarid removing patch has good drug loading effect and high acarid removing effect, and can keep the cleanness and sanitation of the bedding for a long time; the konjac glucomannan acarid-removing patch can be completely biodegraded, is environment-friendly and low-carbon, and has the advantages of convenient material acquisition, low price and simple production process.

The invention has the advantages and beneficial effects that:

1. the konjac glucomannan acarid-removing patch disclosed by the invention fully utilizes the fact that konjac glucomannan is a natural high-molecular polysaccharide, and is supplemented with rosin resin to increase viscosity and change the holding viscosity of an adhesive on the basis of the characteristics of water absorption, film-forming property, water retention property, biodegradability and the like, so that the konjac glucomannan is prevented from falling off when in use;

2. the konjac glucomannan mite-killing patch adopts a physical mite-killing mode, does not harm a human body, is light and thin in texture and is convenient to carry and use;

3. the konjac glucomannan acarid-removing card can be naturally degraded after being discarded, and has high popularization value;

4. the invention has the advantages of simple process, low cost, high quality, convenient use and the like.

The results of comparison between the konjac glucomannan mite-killing patch of the invention and a mite-killing instrument, a mite-killing bag and a common mite-killing patch in the aspects of mite-killing effect, bioavailability, raw material price and potential market are shown in table 1.

TABLE 1 comparison of the Performance test of the Konjac glucomannan film mite-killing patch of the invention and the commercial mite-killing product

Through the test and comparison, the konjac glucomannan film mite-killing patch disclosed by the invention is better than other mite-killing products on the market in indexes such as mite-killing effect, bioavailability, raw material price and potential market, and can become a high-quality mite-killing patch selected by consumers.

Detailed Description

The present invention will be described in further detail with reference to specific examples.