Whole blood separation structure

文档序号:1480996 发布日期:2020-02-28 浏览:30次 中文

阅读说明:本技术 一种全血分离结构 (Whole blood separation structure ) 是由 郝书顺 于 2019-12-19 设计创作,主要内容包括:本发明涉及一种全血分离结构,其包括转盘、储液槽、分离槽以及第二流道,在第二流道上设置有一拐点,该拐点与转盘旋转轴心的径向距离小于分离槽内的液面与转盘旋转轴心的径向距离。本发明通过转盘产生离心力,将从储液槽内加入的全血推入到分离槽内,在分离槽内进行血浆与血细胞的分离,由于血细胞质量较大,会位于分离槽远离旋转轴心的一端,血浆位于分离槽靠近旋转轴心的一端,而由于分离槽没有排气口,当分离槽内的液面没过其与第二流道的连通点之后便会对其中的气体进行压缩,当分离完成后,转盘减速,在空气压力作用下便会将血浆推入到第二流道内,绕过第二流道的拐点,然后转盘再次加速,血浆便会从第二流道排出,进行下一步的操作。(The invention relates to a whole blood separation structure, which comprises a rotary table, a liquid storage tank, a separation tank and a second flow channel, wherein an inflection point is arranged on the second flow channel, and the radial distance between the inflection point and the rotary axis of the rotary table is smaller than the radial distance between the liquid level in the separation tank and the rotary axis of the rotary table. The whole blood added from the liquid storage tank is pushed into the separation tank by the centrifugal force generated by the rotary disc, the plasma and the blood cells are separated in the separation tank, the blood cells are positioned at one end of the separation tank far away from the rotating shaft center due to large mass, the plasma is positioned at one end of the separation tank close to the rotating shaft center, the separation tank is not provided with an exhaust port, the gas in the separation tank is compressed after the liquid level in the separation tank is beyond the communication point of the separation tank and the second flow channel, after the separation is finished, the rotary disc is decelerated, the plasma is pushed into the second flow channel under the action of air pressure and bypasses the inflection point of the second flow channel, then the rotary disc is accelerated again, and the plasma is discharged from the second flow channel to carry out the next operation.)

1. A whole blood separation structure is characterized by comprising a rotary table (1), a liquid storage tank (2) arranged on the rotary table (1), a separation tank communicated with the liquid storage tank (2) through a first flow channel (3), and a second flow channel (6) arranged on the separation tank;

an inflection point is arranged on the second flow channel (6), and the radial distance between the inflection point and the rotation axis of the rotating disc (1) is smaller than the radial distance between the liquid level in the separation tank and the rotation axis of the rotating disc (1).

2. A whole blood separation structure according to claim 1, wherein the volume outside the point of communication with the second flow path (6) in the separation tank is more than 70% of the amount of blood added to the reservoir (2).

3. A whole blood separation structure according to claim 1 or 2, wherein the separation vessel comprises a blood cell vessel (4) and a blood plasma vessel (5) which communicate with each other via a third flow path, the second flow path (6) communicates with the third flow path, and the sum of the volume of the portion of the third flow path located outside the connection point with the second flow path (6) and the blood cell vessel (4) is greater than 70% of the amount of blood added in the reservoir tank (2).

4. A whole blood separation structure according to claim 1, wherein the second flow path (6) has a U-shape, and the position of the bottom end of the U-shape is an inflection point.

5. A whole blood separation structure according to claim 3, wherein the plasma tank (5) is connected to the overflow tank (8) through a fourth flow path (7).

6. A whole blood separating structure according to claim 5, wherein the overflow vessel (8) is located at a radial distance from the rotational axis of the rotary plate (1) which is greater than the radial distance between the plasma vessel (5) and the rotational axis of the rotary plate (1).

Technical Field

The invention relates to a whole blood separation structure.

Background

In experiments and modern medical treatment, whole blood is often required to be separated, plasma is extracted for further experiments or detection, a special centrifuge is mostly adopted in the current separation mode, the whole blood is separated by using centrifugal force, the separated plasma is taken out, and the next operation is carried out. Although whole blood centrifugation can be automatically completed by a machine, plasma removal for the next operation needs to be completed manually, which consumes a certain amount of manpower.

Disclosure of Invention

The invention aims to provide a whole blood separation structure which can automatically realize the separation and the taking out of whole blood.

The technical scheme adopted by the invention is as follows: a whole blood separation structure comprises a rotary table, a liquid storage tank arranged on the rotary table, a separation tank communicated with the liquid storage tank through a first flow channel, and a second flow channel arranged on the separation tank;

and the second flow passage is provided with an inflection point, and the radial distance between the inflection point and the rotating shaft center of the rotating disc is smaller than the radial distance between the liquid level in the separation tank and the rotating shaft center of the rotating disc.

Further, the volume of the separation tank outside the communication point with the second flow channel is more than 70% of the blood adding amount in the liquid storage tank.

Further, the separation tank comprises a blood cell tank and a blood plasma tank which are communicated through a third flow channel, the second flow channel is communicated with the third flow channel, and the sum of the volume of the part of the third flow channel, which is positioned outside the connection point of the third flow channel and the blood cell tank, and the blood cell tank is more than 70% of the blood adding amount in the liquid storage tank.

Further, the second flow channel is U-shaped, and the position of the U-shaped bottom end of the second flow channel is radially inward relative to the liquid level in the separation tank.

Furthermore, the plasma groove is communicated with an overflow groove through a fourth flow channel.

Furthermore, the radial distance between the overflow groove and the rotating axis of the turntable is greater than that between the plasma groove and the rotating axis of the turntable.

The invention has the positive effects that: the whole blood added from the liquid storage tank is pushed into the separation tank under the action of centrifugal force through the rotary disc, the plasma and blood cells are separated in the separation tank, the blood cells are located at one end, far away from the rotating shaft center, of the separation tank, the plasma is located at one end, close to the rotating shaft center, of the separation tank, due to the fact that the separation tank is not provided with the exhaust port, the gas in the separation tank is compressed after the liquid level in the separation tank is beyond the communication point of the liquid level and the second flow channel, after separation is completed, the rotary disc is decelerated, the plasma is pushed into the second flow channel under the action of air pressure, the plasma bypasses the inflection point of the second flow channel, then the rotary disc is accelerated again, the plasma is discharged from the second flow channel, and next operation is carried out.

Drawings

FIG. 1 is a schematic view of the structure of the present invention.

Detailed Description

As shown in fig. 1, the present invention includes a rotating disk 1, a liquid storage tank 2 disposed on the rotating disk 1 near the rotating axis, a separating tank connected to the liquid storage tank 2 via a first flow channel 3, and a second flow channel 6 disposed on the separating tank, wherein the distance between the separating tank and the rotating axis is greater than the distance between the liquid storage tank 2 and the rotating axis, that is, the separating tank is located radially outward relative to the liquid storage tank 2.

The second flow channel 6 is provided with an inflection point, and the radial distance between the inflection point and the rotation axis of the rotating disc 1 is smaller than the radial distance between the liquid level in the separation tank and the rotation axis of the rotating disc 1. Therefore, according to the principle of the communicating vessel, when the rotating disc rotates for centrifugal separation, the liquid in the second flow channel 6 can not bypass the inflection point to flow out. The second flow passage 6 is U-shaped, and the position of the U-shaped bottom end is an inflection point

According to the ratio of plasma to blood cells in the whole blood, in order to discharge only plasma, the volume outside the point of communication with the second channel 6 in the separation tank is more than 70% of the amount of blood added in the reservoir 2, and certainly, the amount of blood added cannot be exceeded, otherwise, the liquid cannot be discharged.

As another embodiment of the present invention, the separation vessel comprises a blood cell vessel 4 and a plasma vessel 5 which are communicated with each other via a third channel, the first channel 3 is communicated with the blood cell vessel 4, the second channel 6 is communicated with the third channel, and the sum of the volume of the portion of the third channel located outside the connection point with the second channel 6 and the blood cell vessel 4 is more than 70% of the amount of blood added in the reservoir 2.

As a further improvement of the invention, the plasma tank 5 is communicated with an overflow tank 8 through a fourth flow passage 7, and the radial distance between the overflow tank 8 and the rotation axis of the turntable 1 is greater than that between the plasma tank 5 and the rotation axis of the turntable 1. When a large amount of blood is added to the reservoir 2, the excess blood enters the overflow tank 8.

The turntable 1 may be driven in rotation in various forms, for example in the form of a disc drive similar to a CD/DVD, which is known to the person skilled in the art and will not be described in further detail herein.

When the blood plasma detection device is used, blood is added into the liquid storage tank 2 from a liquid adding port on the liquid storage tank 2, then the rotary disc rotates, the whole blood is pushed into the blood cell tank 4 under the action of centrifugal force, centrifugal separation is carried out in the tank, gas in the plasma tank 5 is compressed, after separation is finished, the rotary disc 1 decelerates, the compressed gas expands, the plasma is pushed into the second flow channel 6 and bypasses the inflection point of the second flow channel 6, the rotary disc 1 accelerates again, and according to the principle of a communicating vessel, the plasma can be discharged from the second flow channel 6 so as to carry out the next test detection operation.

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