一种食欲素受体拮抗剂的晶型及其制备方法和用途
阅读说明:本技术 一种食欲素受体拮抗剂的晶型及其制备方法和用途 (Crystal form of orexin receptor antagonist and preparation method and application thereof ) 是由 陈敏华 张炎锋 黄春香 张晓宇 于 2018-07-31 设计创作,主要内容包括:一种化合物Lemborexant的晶型及其制备方法,含有该晶型的药物组合物,以及该晶型在制备食欲素受体拮抗剂、治疗失眠症和不规则睡眠-觉醒节律障碍药物制剂中的用途。提供的化合物Lemborexant的晶型比现有技术具有一种或多种改进的特性,对未来该药物的优化和开发具有重要价值。<Image he="606" wi="623" file="DDA0002323472750000011.GIF" imgContent="drawing" imgFormat="GIF" orientation="portrait" inline="no"></Image>(A crystal form of a compound Lemborexant, a preparation method thereof, a pharmaceutical composition containing the crystal form and application of the crystal form in preparing an orexin receptor antagonist and a pharmaceutical preparation for treating insomnia and irregular sleep-wake dysrhythmia. The provided crystal form of the compound Lemborexant has one or more improved properties compared with the prior art, and has important value on the optimization and development of the medicine in the future.)
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