阅读说明：本技术 一种大蒜素淡斑化妆品及其制备方法 (Allicin spot-lightening cosmetic and preparation method thereof ) 是由 张毅 柴菊红 于 2019-09-18 设计创作，主要内容包括：本发明涉及淡斑化妆品领域,更具体地,本发明涉及一种大蒜素淡斑化妆品及其制备方法,所述大蒜素淡斑化妆品的制备原料包括A组分、B组分以及C组分；按重量份计,所述A组分的制备原料包括2～5份润肤剂、0.1～1份表面活性剂；所述B组分的制备原料包括80～90份水、7～10份护肤剂、0.05～0.15份螯合剂、0.02～0.1份酸碱调节剂；所述C组分包括0.1～0.3份防腐剂、0.1～0.3份大蒜素。本发明提供的大蒜素淡斑化妆品安全不刺激,使用5周后淡斑率达到84％以上,停用产品8周后不反弹,同时还能有效抗细菌、大肠杆菌、白色念珠菌、烟曲霉菌、阿米巴原虫、阴道滴虫,使人们在日常生活中免受其感染。(The invention relates to the field of spot-fading cosmetics, in particular to an allicin spot-fading cosmetic and a preparation method thereof, wherein the allicin spot-fading cosmetic comprises a component A, a component B and a component C; the component A is prepared from 2-5 parts by weight of an emollient and 0.1-1 part by weight of a surfactant; the preparation raw materials of the component B comprise 80-90 parts of water, 7-10 parts of skin care agent, 0.05-0.15 part of chelating agent and 0.02-0.1 part of acid-base regulator; the component C comprises 0.1-0.3 part of preservative and 0.1-0.3 part of allicin. The allicin spot-fading cosmetic provided by the invention is safe and non-irritant, the spot-fading rate reaches over 84% after 5 weeks of use, the product does not rebound after 8 weeks of non-use, and meanwhile, the allicin spot-fading cosmetic can effectively resist bacteria, escherichia coli, candida albicans, aspergillus fumigatus, amoeba and trichomonas vaginalis, so that people can be prevented from being infected in daily life.)

1. An allicin spot-lightening cosmetic is characterized in that the allicin spot-lightening cosmetic is prepared from raw materials comprising a component A, a component B and a component C; the component A is prepared from 2-5 parts by weight of an emollient and 0.1-1 part by weight of a surfactant; the preparation raw materials of the component B comprise 80-90 parts of water, 7-10 parts of skin care agent, 0.05-0.15 part of chelating agent and 0.02-0.1 part of acid-base regulator; the component C comprises 0.1-0.3 part of preservative and 0.1-0.3 part of allicin.

2. The allicin speckle lightening cosmetic as claimed in claim 1, wherein the raw material for preparing the component a further comprises 1 to 3 parts by weight of a vitamin C derivative.

3. An allicin spot-lightening cosmetic as claimed in claim 2, wherein the vitamin C derivative is at least one selected from the group consisting of vitamin C ethyl ether dipalmitate, vitamin C palmitate, trisodium ascorbyl palmitate phosphate, vitamin C ethyl ether.

4. The allicin spot-lightening cosmetic according to claim 3, wherein the raw material for preparing the component A further comprises 0.5 to 2 parts by weight of polyorganosiloxane.

5. An allicin spot-lightening cosmetic composition according to claim 4, wherein said polyorganosiloxane is at least one member selected from the group consisting of polydimethylsiloxane, cyclomethicone, phenyl trimethicone, polytrimethylsilylaminodimethylsiloxane, stearyloxytrimethylsilane and cyclopentadimethylsiloxane.

6. An allicin spot-lightening cosmetic product according to claim 5, wherein the polyorganosiloxane comprises cyclopentadimethylsiloxane.

7. An allicin speckle fading cosmetic composition according to any one of claims 1 to 6 wherein the emollient is selected from at least one of glycerin, butylene glycol, propylene glycol, polyglycerol-3, sodium hyaluronate, hydrogenated lecithin, jojoba oil, hydrogenated polyisobutene, neopentyl glycol dicaprylate/dicaprate, squalane, hydrogenated glyceryl cocoate, hydrogenated coconut oil, hydrogenated lanolin, hydrogenated palm oil glyceride, hydrogenated palm kernel oil, hydrogenated soybean oil.

8. The allicin spot-lightening cosmetic of claim 7, wherein said emollient comprises hydrogenated polyisobutene and neopentyl glycol dicaprylate/dicaprate; the weight ratio of hydrogenated polyisobutene to neopentyl glycol dicaprylate/dicaprate is 1: (1.5 to 3).

9. An allicin speckle lightening cosmetic composition according to any one of claims 1 to 6, wherein the skin care agent is at least one selected from the group consisting of glycerin, butylene glycol, propylene glycol, jojoba oil, sodium hyaluronate, glycerin polymethacrylate, PVM/MA copolymer, and sodium polyacrylate.

10. A method for preparing the allicin spot-lightening cosmetic according to any one of claims 1 to 9, which comprises: uniformly dispersing the component A; after the component B is uniformly dispersed, adding the component A, and stirring for 5-8 minutes; and cooling and adding the completely dissolved component C.

Technical Field

The invention relates to the field of spot-fading cosmetics, in particular to an allicin spot-fading cosmetic and a preparation method thereof.

Background

Melanin is an important factor determining the skin color of a human body, and under a normal physiological state, melanin in the skin can protect the skin from ultraviolet rays. When the melanin anabolism mechanism is disturbed due to external invasion, hormone imbalance, aging or other factors, the melanin in the basal layer of the epidermis is increased, the color of partial or whole skin is deepened, and pigmentation skin diseases such as freckle, chloasma, cyasma, senile plaque, melanoma and the like are caused, so that the appearance of a human is influenced. The biosynthesis steps of the melanin comprise: tyrosine in melanocyte tissue is converted into dopa under the action of tyrosinase, dopa is further converted into dopaquinone under the catalysis of tyrosinase, dopaquinone is further converted into dopachrome, 5, 6-dihydroxyindole, 5, 6-indoloquinone, and finally into melanin. Melanin granules are synthesized and transported by the dendrites into keratinocytes.

Because the active ingredients of the existing whitening and spot-fading cosmetics have limited effect, slow spot-fading effect and easy rebound, and whitening and spot-fading products are easy to discolor, the sodium sulfite is added into the products on the market to prevent the spot-fading agent from discoloring, so that the odor is heavy and the skin is stimulated.

Therefore, the development of a whitening spot-fading product which has a better spot-fading effect, does not rebound and is not easy to discolor needs to be solved.

Disclosure of Invention

In view of the problems in the prior art, the invention provides an allicin spot-lightening cosmetic, which is prepared from raw materials comprising a component A, a component B and a component C; the component A is prepared from 2-5 parts by weight of an emollient and 0.1-1 part by weight of a surfactant; the preparation raw materials of the component B comprise 80-90 parts of water, 7-10 parts of skin care agent, 0.05-0.15 part of chelating agent and 0.02-0.1 part of acid-base regulator; the component C comprises 0.1-0.3 part of preservative and 0.1-0.3 part of allicin.

As a preferable technical scheme of the invention, the raw materials for preparing the component A also comprise 1-3 parts by weight of vitamin C derivatives.

In a preferred embodiment of the present invention, the vitamin C derivative is at least one selected from the group consisting of vitamin C ethyl ether dipalmitate, vitamin C palmitate, trisodium ascorbyl palmitate phosphate, and vitamin C ethyl ether.

As a preferable technical scheme of the invention, the preparation raw material of the component A also comprises 0.5-2 parts by weight of polyorganosiloxane.

In a preferred embodiment of the present invention, the polyorganosiloxane is at least one selected from the group consisting of polydimethylsiloxane, cyclomethicone, phenyl trimethicone, polytrimethylsilylaminomethicone, stearyloxytrimethylsilane and cyclopentadimethicone.

As a preferred embodiment of the present invention, the polyorganosiloxane includes cyclopentadimethylsiloxane.

As a preferred embodiment of the present invention, the emollient is at least one selected from glycerin, butylene glycol, propylene glycol, polyglycerin-3, sodium hyaluronate, hydrogenated lecithin, jojoba oil, hydrogenated polyisobutene, neopentyl glycol dicaprylate/dicaprate, squalane, hydrogenated cocoglyceride, hydrogenated coconut oil, hydrogenated lanolin, hydrogenated palm oil glyceride, hydrogenated palm kernel oil, and hydrogenated soybean oil.

As a preferred embodiment of the present invention, the emollient comprises hydrogenated polyisobutene and neopentyl glycol dicaprylate/dicaprate; the weight ratio of hydrogenated polyisobutene to neopentyl glycol dicaprylate/dicaprate is 1: (1.5 to 3).

In a preferred embodiment of the present invention, the skin care agent is at least one selected from the group consisting of glycerin, butylene glycol, propylene glycol, jojoba oil, sodium hyaluronate, glycerin polymethacrylate, PVM/MA copolymer, and sodium polyacrylate.

The second aspect of the present invention provides a method for preparing an allicin spot-lightening cosmetic, which comprises: uniformly dispersing the component A; after the component B is uniformly dispersed, adding the component A, and stirring for 5-8 minutes; and cooling and adding the completely dissolved component C.

Compared with the prior art, the invention has the following beneficial effects:

the allicin spot-fading cosmetic provided by the invention is safe and non-irritant, the spot-fading rate reaches over 84% after 5 weeks of use, the product does not rebound after 8 weeks of non-use, and meanwhile, the allicin spot-fading cosmetic can effectively resist bacteria, escherichia coli, candida albicans, aspergillus fumigatus, amoeba and trichomonas vaginalis, so that people can be prevented from being infected in daily life.

Detailed Description

The present invention is illustrated by the following specific embodiments, but is not limited to the specific examples given below.

The invention provides an allicin spot-lightening cosmetic, which is prepared from raw materials comprising a component A, a component B and a component C; the component A is prepared from 2-5 parts by weight of an emollient and 0.1-1 part by weight of a surfactant; the preparation raw materials of the component B comprise 80-90 parts of water, 7-10 parts of skin care agent, 0.05-0.15 part of chelating agent and 0.02-0.1 part of acid-base regulator; the component C comprises 0.1-0.3 part of preservative and 0.1-0.3 part of allicin.

In one embodiment, the raw materials for preparing the component A further comprise 1-3 parts by weight of vitamin C derivatives.

In one embodiment, the raw material for preparing the component A further comprises 0.5-2 parts of polyorganosiloxane.

In a preferred embodiment, the allicin spot-lightening cosmetic is prepared from raw materials comprising a component A, a component B and a component C; the preparation raw materials of the component A comprise 3 parts of emollient, 0.35 part of surfactant, 1.5 parts of vitamin C derivative and 1 part of polyorganosiloxane in parts by weight; the raw materials for preparing the component B comprise 85 parts of water, 8.15 parts of skin care agent, 0.1 part of chelating agent and 0.06 part of pH regulator; the component C comprises 0.15 part of preservative and 0.2 part of allicin.

< component A >

Skin-moistening agent

Emollients are cosmetic ingredients that help maintain the skin soft, pliable, and smooth its appearance. The function of emollients is to provide lubrication to the skin surface. Generally fills the spaces in the skin surface, replacing the lipid lost in the stratum corneum, reducing the scaly skin, improving skin elasticity.

In one embodiment, the emollient is selected from at least one of glycerin, butylene glycol, propylene glycol, polyglycerol-3, sodium hyaluronate, hydrogenated lecithin, jojoba oil, hydrogenated polyisobutylene, neopentyl glycol dicaprylate/dicaprate, squalane, hydrogenated cocoglycerides, hydrogenated coconut oil, hydrogenated lanolin, hydrogenated palm oil glyceride, hydrogenated palm kernel oil, hydrogenated soybean oil.

Preferably, the emollient includes hydrogenated polyisobutene and neopentyl glycol dicaprylate/dicaprate; the weight ratio of hydrogenated polyisobutene to neopentyl glycol dicaprylate/dicaprate is 1: (1.5-3); more preferably, the hydrogenated polyisobutene and neopentyl glycol dicaprylate/dicaprate weight ratio is 1: 2.

the hydrogenated polyisobutene is purchased from Beijing Xinnuojiu Hengkomao Co., Ltd and has the brand number of H-300E.

Surface active agent

Surfactant (surfactant) is a substance added in a small amount to change the interface state of a solution system obviously, has fixed hydrophilic and lipophilic groups, and can be arranged on the surface of the solution in an oriented manner. The molecular structure of the surfactant has amphipathy: one end is a hydrophilic group, and the other end is a hydrophobic group; the hydrophilic group is often a polar group, such as carboxylic acid, sulfonic acid, sulfuric acid, amino or amino groups and salts thereof, hydroxyl, amide, ether linkages, and the like may also be used as the polar hydrophilic group; and the hydrophobic group is often a non-polar hydrocarbon chain, such as a hydrocarbon chain of 8 or more carbon atoms. The surfactant is divided into ionic surfactant (including cationic surfactant and anionic surfactant), nonionic surfactant, amphoteric surfactant, compound surfactant, other surfactants, etc.

As the surfactant, lauric acid polyoxyethylene ether, castor oil polyoxyethylene ether, alkylphenol polyoxyethylene ether, hydrogenated castor oil polyoxyethylene ether, Tween-80, span-80, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer and the like can be cited.

In one embodiment, the surfactant comprises hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer.

The hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer is purchased from An chemical Co., Ltd, Guangzhou city and has the brand number of EMT-10.

Vitamin C derivatives

The vitamin C derivative is prepared by processing vitamin C serving as a raw material by modern scientific technology.

In one embodiment, the vitamin C derivative is selected from at least one of vitamin C ethyl ether dipalmitate, vitamin C palmitate, trisodium ascorbyl palmitate phosphate, vitamin C ethyl ether; preferably, the vitamin C derivative comprises trisodium ascorbyl palmitate phosphate.

Polyorganosiloxane

Polyorganosiloxanes are hybrid materials consisting of pendant organic groups pendant along the inorganic siloxane backbone, known as semi-inorganic polymers. According to the second law of thermodynamics and the principle of lang-muir surface effect independence, polyorganosiloxanes have much lower surface tensions than silica.

In one embodiment, the polyorganosiloxane is selected from at least one of polydimethylsiloxane, cyclomethicone, phenyl trimethicone, polytrimethylsilylaminodimethylsiloxane, stearyloxytrimethylsilane, cyclopentadimethicone; preferably, the polyorganosiloxane comprises cyclopentadimethylsiloxane.

The cyclopentadimethicone is purchased from Anpin chemical Co., Ltd, Guangzhou, under the brand name DC 345.

The applicant surprisingly found that the addition of cyclopenta dimethyl siloxane can improve the touch of the cosmetic, reduce the irritation caused by allicin and improve the spot-lightening effect, and in addition, the addition of hydrogenated polyisobutene and trisodium ascorbyl palmitate phosphate can make the spot-lightening effect more obvious, shorten the spot-lightening time and prolong the spot-lightening effect, probably because the allicin promotes the metabolism of the skin, the skin which is newly changed is thinner, the resistance is weaker, the addition of hydrogenated polyisobutene and trisodium ascorbyl palmitate phosphate is weaker, meanwhile, the external stimulation of the skin is prevented under the synergistic effect of the neopentyl glycol dicaprylate/dicaprate and the cyclopentadimethylsiloxane, so that a layer of protective film is formed on the epidermis of the skin to protect the skin from being damaged, the moistening type of the skin is increased, the missing moisture is supplemented to the deep layer of the skin, the skin cells are in a full and transparent and closely arranged healthy state, the skin is naturally, more and more fine and moist, and meanwhile, the blood circulation of the skin can be promoted, and the metabolism is enhanced. Meanwhile, the addition of hydrogenated polyisobutene and trisodium ascorbyl palmitate phosphate can improve the irritation of the allicin to the skin.

< component B >

Skin care agent

Skin care agents refer to agents capable of conditioning the skin.

In one embodiment, the skin care agent is selected from at least one of glycerin, butylene glycol, propylene glycol, jojoba oil, sodium hyaluronate, glycerin polymethacrylate, PVM/MA copolymer, sodium polyacrylate.

Preferably, the skin benefit agent comprises butylene glycol, glycerin, propylene glycol, glycerin polymethacrylate, PVM/MA copolymer, sodium polyacrylate.

Further preferably, the skin care agent comprises, by weight, 2.5-3.5 parts of butanediol, 2.5-3.5 parts of glycerol, 0.8-1.2 parts of propylene glycol, 0.2-0.6 part of glycerol polymethacrylate, 0.5-1 part of PVM/MA copolymer and 0.1-0.2 part of sodium polyacrylate; more preferably, the skin care agent comprises 3 parts of butanediol, 3 parts of glycerol, 1 part of propylene glycol, 0.4 part of glycerol polymethacrylate, 0.6 part of PVM/MA copolymer and 0.15 part of sodium polyacrylate in parts by weight.

PVM/MA copolymer: polyvinyl methyl ether/maleic anhydride copolymers.

The sodium polyacrylate of the invention is purchased from Guangzhou optimization industry Co., Ltd and has the brand number of MV 60.

Chelating agents

The metal atom or ion reacts with a ligand containing two or more coordinating atoms to form a complex having a cyclic structure, which is called a chelate. Such ligand substances capable of forming chelates are called chelating agents, also known as complexing agents.

As the chelating agent, ethylenediaminetetraacetic acid, disodium ethylenediaminetetraacetate, tetrasodium ethylenediaminetetraacetate, calcium sodium ethylenediaminetetraacetate, magnesium sodium ethylenediaminetetraacetate, and the like can be exemplified.

In one embodiment, the chelating agent comprises disodium edetate.

Acid-base regulator

The pH regulator is used for regulating pH.

In one embodiment, the pH adjusting agent is selected from at least one of phosphoric acid, sorbitol, arginine, sodium citrate, sodium hydroxide, triethanolamine, monoethanolamine; preferably, the pH adjusting agent comprises triethanolamine.

< component C >

Preservative

The preservative can inhibit the activity of microorganisms, so that the product has a certain preservation period, and certain measures must be taken to prevent the infection and the propagation of the microorganisms. The use of preservatives has proven to be one of the most economical, effective and straightforward ways to achieve the above objectives.

In one embodiment, the preservative IS selected from at least one of imidazolidinyl urea, methylparaben, phenoxyethanol, germall-IS 45, DMDM hydantoin, brobopol, methylparaben; preferably, the preservative comprises methylparaben.

Allicin

The dietary therapy value of garlic is mainly that allicin, an effective component in garlic, plays a role. Biochemical analysis shows that fresh garlic contains no allicin but alliin, its precursor. Alliin is present in garlic in an unstable odorless form. Tests prove that alliin in fresh garlic is activated by alliinase after being impacted (sliced or crushed) to catalyze the alliin to form allicin, and the allicin is further decomposed to form sulfides with strong odor. The garlic adopts different solvents, and different products can be obtained by controlling different conditions. According to the mechanism, proper solvent can be selected, reaction conditions are controlled, the garlic stock solution with the effective components can be deodorized and preserved, and then the garlic stock solution is processed into garlic series products.

The allicin of the present invention is purchased from Shanghai Ji to Biochemical technology Co., Ltd.

The second aspect of the present invention provides a method for preparing an allicin spot-lightening cosmetic, which comprises: uniformly dispersing the component A; after the component B is uniformly dispersed, adding the component A, and stirring for 5-8 minutes; and cooling and adding the completely dissolved component C.

In one embodiment, the allicin spot-lightening cosmetic is prepared by a method comprising: uniformly dispersing the component A; after the component B is uniformly dispersed, adding the component A, and stirring for 7 minutes; and cooling and adding the completely dissolved component C.