阅读说明：本技术 一种高原性人类疾病模型制备环境模拟系统 (Plateau nature human disease model preparation environmental simulation system ) 是由 钟浩 于 2019-11-06 设计创作，主要内容包括：本发明公开了一种高原性人类疾病模型制备环境模拟系统,包括功能设备集成底座和设置在功能设备集成底座上的饲养仓,所述饲养仓具有无极调控微负压装置、高原低氧环境模拟装置、高原光照环境模拟装置、高原温度环境模拟装置、高原湿度环境模拟装置、动物行为学远程观察单元,所述饲养仓内设置有若干代谢笼,饲养仓前后箱体上设置有观察窗和若干操作窗,饲养仓左右箱体上分别设置有小物件传递窗和大物件传递窗,所述代谢笼还包括设置在代谢笼上的投料斗、饮水瓶和设置在代谢笼下方的聚粪斗、尿液排出口、粪便排出口。能够很好地模拟高原环境,并且可以同时培养多种动物,造模动物多。(The invention discloses a highland human disease model preparation environment simulation system which comprises a functional equipment integration base and a feeding bin arranged on the functional equipment integration base, wherein the feeding bin is provided with a stepless regulation and control micro negative pressure device, a plateau hypoxia environment simulation device, a plateau illumination environment simulation device, a plateau temperature environment simulation device, a plateau humidity environment simulation device and an animal behavior remote observation unit, a plurality of metabolism cages are arranged in the feeding bin, an observation window and a plurality of operation windows are arranged on a front box body and a rear box body of the feeding bin, a small object transfer window and a large object transfer window are respectively arranged on a left box body and a right box body of the feeding bin, and the metabolism cages further comprise a feeding hopper, a drinking bottle, a feces collecting hopper, an urine discharge port and an feces discharge port which are arranged on the metabolism cages. Can well simulate plateau environment, can cultivate multiple animals simultaneously, make the mould animal many.)

1. The utility model provides a plateau nature human disease model preparation environmental simulation system, includes functional equipment integrated base (1) and sets up raising storehouse (2) on functional equipment integrated base (1), raising storehouse (2) and have electrodeless regulation and control little negative pressure device, plateau low oxygen environment analogue means, plateau illumination environment analogue means (15), plateau temperature environment analogue means (16), plateau humidity environment analogue means (17), animal behavior remote observation unit (18), its characterized in that: the feeding bin is characterized in that a plurality of metabolism cages (3) are arranged in the feeding bin (2), an observation window (4) and a plurality of operation windows (5) are arranged on the front box body and the rear box body of the feeding bin (2), small object transfer windows (6) and large object transfer windows (7) are respectively arranged on the left box body and the right box body of the feeding bin (2), and each metabolism cage (3) further comprises a feeding hopper (8) arranged on the metabolism cage (3), a drinking water bottle (9), a feces collecting hopper (10) arranged below the metabolism cage (3), a urine discharge port (11) and a feces discharge port (12).

2. The high altitude human disease model preparation environment simulation system of claim 1, wherein: the electrodeless regulation and control micro negative pressure device comprises an air inlet system (13), an air exhaust system (14) and a Honeyville or Siemens regulation and control module, wherein the air inlet system (13) is arranged in the functional equipment integration base (1), and the air exhaust system (14) is arranged at the top of the feeding bin (2).

3. The high altitude human disease model preparation environment simulation system of claim 1, wherein: the plateau hypoxia environment simulation device comprises an inert gas source, wherein the inert gas source is connected with an air inlet system (13), a proportional gas valve is arranged between the inert gas source and the air inlet system (13), and the plateau hypoxia environment simulation device further comprises an embedded oxygen tester arranged in a feeding bin (2).

4. The high altitude human disease model preparation environment simulation system of claim 1, wherein: the plateau illumination environment simulation device (15) comprises a visible warm light system and an illumination brightness stepless control system, wherein the visible warm light system is arranged at the top of the feeding bin (2).

5. The high altitude human disease model preparation environment simulation system of claim 1, wherein: the plateau temperature environment simulation device (16) comprises a cooling system, a heating system, a temperature control system and a temperature acquisition and display system.

6. The high altitude human disease model preparation environment simulation system of claim 1, wherein: the plateau humidity environment simulation device (17) comprises a humidifying system, a dehumidifying system, a humidity control system and a humidity acquisition and display system.

7. The high altitude human disease model preparation environment simulation system of claim 1, wherein: the animal behavior remote observation unit (18) comprises a Comms high-definition image acquisition system, a digital video transmission system, a frequency hardware decompression card and a video display system.

Technical Field

The invention belongs to the technical field of animal experimental equipment, and particularly relates to a plateau human disease model preparation environment simulation system.

Background

The plateau environment simulation system can be manufactured in non-plateau areas to generate different altitude and climate conditions, various plateau anoxic environments are simulated, experimental animals can reach expected plateau reaction symptoms according to experimental requirements within a certain time, the experimental animals can show plateau diseases, plateau disease model animals are provided for plateau disease researchers, and medicines for treating or preventing the plateau diseases are convenient to research. The existing environment simulation system can simulate and realize plateau illumination and low oxygen environment, but the success rate of models is low, the death rate of animals is high, and the types of modeling animals are single.

Disclosure of Invention

The invention aims to: provides a plateau human disease model preparation environment simulation system, and solves the problems of low model success rate, high animal mortality rate and single type of modeling animals in the conventional plateau environment simulation system.

The technical scheme adopted by the invention is as follows:

the utility model provides a plateau nature human disease model preparation environmental simulation system, includes functional equipment integrated base and sets up the feed bin on functional equipment integrated base, feed bin has electrodeless regulation and control micro negative pressure device, plateau low oxygen environment analogue means, plateau illumination environment analogue means, plateau temperature environment analogue means, plateau humidity environment analogue means, animal behaviourology remote observation unit, be provided with a plurality of metabolism cages in the feed bin, be provided with observation window and a plurality of operation window around the feed bin on the box, be provided with little article pass-through box and big article pass-through box on the box about the feed bin respectively, the metabolism cage is still including setting up feeding hopper, drinking water bottle on the metabolism cage and setting up gather excrement fill, urine discharge port, excrement discharge port below the metabolism cage.

Furthermore, the electrodeless regulation and control micro-negative pressure device comprises an air inlet system, an air exhaust system and a Honeyville or Siemens regulation and control module, wherein the air inlet system is arranged in the functional equipment integration base, and the air exhaust system is arranged at the top of the feeding bin.

Further, plateau low oxygen environment analogue means includes the inert gas source, the inert gas source is connected with the air inlet system, be provided with the proportion formula pneumatic valve between inert gas source and the air inlet system, still including setting up the embedded oxygen apparatus in raising the storehouse.

Further, the plateau illumination environment simulation device comprises a visible warm light system and an illumination brightness stepless control system, wherein the visible warm light system is arranged at the top of the feeding bin.

Further, the plateau temperature environment simulation device comprises a cooling system, a heating system, a temperature control system and a temperature acquisition and display system.

Further, plateau humidity environment simulation device includes humidification system, dehumidification system, humidity control system and humidity acquisition display system.

Furthermore, the animal behavior remote observation unit comprises a Comms high-definition image acquisition system, a digital video transmission system, a frequency hardware decompression card and a video display system.

In summary, due to the adoption of the technical scheme, the invention has the beneficial effects that:

1. the non-full-automatic control system needs artificial observation and manual adjustment of the internal environment of the isolator, but the artificial adjustment can more directly simulate the experimental environment according to the requirement, and can effectively reduce the occurrence of accidents compared with the automatic control environment simulation.

2. A plurality of metabolism cages that this system set up can cultivate multiple animal simultaneously, and the molding animal is many.

3. The system disclosed by the invention can well simulate the plateau pressure, temperature, humidity and low oxygen environment, has the function of remotely observing animal behaviors, and guarantees real-time monitoring in the experimental process and traceability of the operation process after the experiment is finished.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.

FIG. 1 is a front view of a plateau human disease model preparation environment simulation system of the present invention;

FIG. 2 is a schematic perspective view of a plateau human disease model preparation environment simulation system according to the present invention;

FIG. 3 is a schematic perspective view of a metabolic cage;

the labels in the figure are: 1-a functional equipment integration base, 2-a feeding bin, 3-a metabolism cage, 4-an observation window, 5-an operation window, 6-a small object transfer window, 7-a large object transfer window, 8-a feeding hopper, 9-a drinking water bottle, 10-a feces gathering hopper, 11-a urine discharge port, 12-a feces discharge port, 13-an air inlet system, 14-an air exhaust system, 15-a plateau illumination environment simulation device, 16-a plateau temperature environment simulation device, 17-a plateau humidity environment simulation device, 18-an animal behavior remote observation unit and 19-a functional control panel.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the detailed description and specific examples, while indicating the preferred embodiment of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.

Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present invention without making any creative effort, shall fall within the protection scope of the present invention.

It is noted that relational terms such as "first" and "second," and the like, may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.

The features and properties of the present invention are described in further detail below with reference to examples.