聚赖氨酸衍生物稳定包含一种或多种盐的固体基组合物

文档序号:1618119 发布日期:2020-01-10 浏览:27次 >En<

阅读说明:本技术 聚赖氨酸衍生物稳定包含一种或多种盐的固体基组合物 (Polylysine derivatives stabilize solid-based compositions comprising one or more salts ) 是由 M·卡尔特 J·鲁德 H·维特勒 M·迈泽 F·克利佩尔 T·施罗德-格里萌邦特 H-P 于 2018-05-11 设计创作,主要内容包括:本发明涉及一种选自聚赖氨酸衍生物的聚合物稳定剂,其中所述聚赖氨酸衍生物通过包括以下步骤的方法获得:I.将赖氨酸水溶液加热至沸腾;II.将赖氨酸水溶液的温度升高至约105-约180℃的反应温度;III.保持反应温度在约105-约180℃的范围内,直至i.当在160℃下测量时,反应混合物的熔体粘度为约350-约6,500mPa*s,ii.获得约100-约500mg KOH/g的胺值;IV.任选地,释放所所施加的真空;V.相对于反应混合物中所含的聚赖氨酸的理论量,以2.5-10mol%的量添加烷基羧酸或烯基羧酸,VI.将反应温度提高或保持在约105-约180℃的范围内,直至游离烷基羧酸或烯基羧酸的量相对于反应混合物总重量为≤9%,其中在步骤(a)、(b)和/或(c)中施加真空,并且在整个方法期间连续除去水。(The present invention relates to a polymeric stabiliser selected from polylysine derivatives, wherein the polylysine derivatives are obtained by a process comprising the steps of: I. heating the lysine water solution to boiling; raising the temperature of the aqueous lysine solution to a reaction temperature of about 105 to about 180 ℃; maintaining the reaction temperature in the range of from about 105 to about 180 ℃ until i. the melt viscosity of the reaction mixture is from about 350 to about 6,500mPa s when measured at 160 ℃, ii. an amine value of from about 100 to about 500mg KOH/g is obtained; optionally, releasing the applied vacuum; v. adding an alkyl or alkenyl carboxylic acid in an amount of 2.5 to 10 mol% relative to the theoretical amount of polylysine contained in the reaction mixture, vi. increasing or maintaining the reaction temperature in the range of about 105 to about 180 ℃ until the amount of free alkyl or alkenyl carboxylic acid is ≦ 9% relative to the total weight of the reaction mixture, wherein vacuum is applied in steps (a), (b) and/or (c) and water is continuously removed during the entire process.)

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