阅读说明：本技术 激光溅射超声分子束源-离子阱质谱装置及其操作方法 (Laser sputtering ultrasonic molecular beam source-ion trap mass spectrum device and operation method thereof ) 是由 吴晓楠 张谛 徐福兴 刘梓壮 周鸣飞 于 2019-08-01 设计创作，主要内容包括：本发明属于质谱分析技术领域,具体为激光溅射超声分子束源-离子阱质谱装置及其操作方法。本发明装置包括：离子源部分,离子引入区,分隔圆锥体,四极杆系统,离子阱系统,探测器,冷却器；分隔圆锥体呈喇叭状,将空间分隔为前、后两个腔体；离子源部分和离子引出区部分位于前腔体中,四级杆和离子阱系统以及探测器,冷却器位于后腔体中.本发明利用激光溅射超声分子束离子源,通过调控靶材成份和载气成份,合成一些高活性的气相离子,并且充分利用离子阱作为串联质谱分析的特点,对这些离子的结构和反应进行分析。本发明还可以实现离子任意动能的碰撞诱导解离。(The invention belongs to the technical field of mass spectrometry, and particularly relates to a laser sputtering ultrasonic molecular beam source-ion trap mass spectrometry device and an operation method thereof. The device of the invention comprises: the ion source part, the ion introducing area, the separating cone, the quadrupole rod system, the ion trap system, the detector and the cooler; the separating cone is horn-shaped and separates the space into a front cavity and a rear cavity; the invention utilizes laser sputtering ultrasonic molecular beam ion source to synthesize some high-activity gas-phase ions by regulating and controlling target material components and carrier gas components, and fully utilizes the characteristic of ion trap as tandem mass spectrometry to analyze the structure and reaction of the ions. The invention can also realize the collision induced dissociation of any kinetic energy of ions.)

1. A laser sputtering ultrasonic molecular beam source-ion trap mass spectrum device is characterized by comprising: ion source part, ion introduction area, separation cone, quadrupole rod system, ion trap system, detector, cooler:

the ion source section includes: an ion source block, wherein the ion source block is provided with a laser pore canal with the diameter of 0.1-5mm and a carrier gas pipeline with the inner diameter of 0.1-5mm vertical to the laser pore canal; the target material is positioned beside the ion source block and is opposite to the laser channel, and the target material is driven by a motor to rotate continuously; bombarding the target material by laser through a laser pore channel on the metal block; the carrier gas is introduced into the carrier gas pipeline through the first electromagnetic pulse valve; the outlet of the carrier gas pipeline is connected with a rapid flow pipe through a connecting pipe, and the rapid flow pipe is a cylinder with the length of 10-150mm and the inner diameter of 0.3-6 mm; a small hole is formed in the middle of the rapid flow pipe, and reaction gas I is introduced through a second electromagnetic pulse valve;

the ion introducing area part comprises three electrodes, the thickness of each electrode is 0.2-5mm, the first electrode is a metal sheet, the second electrode and the third electrode are metal sheets with grooves in the middle, and welded metal nets are arranged in the grooves; the ion introducing area part is vertical to the direction of the ion source;

the middle of the separation cone is provided with a hole with the diameter of 0.1-10mm, the separation cone is conical, and the space is divided into a front cavity and a rear cavity; the ion source part and the ion leading-out area part are positioned in the front cavity, and the quadrupole rod, the ion trap system, the detector and the cooler are positioned in the rear cavity;

the quadrupole rod system is arranged in the cavity behind the cone and is right opposite to the cone, and the quadrupole rods are used for allowing the ion selective mass to pass through or not to pass through; then sending the ion beam into an ion trap system;

the ion trap system includes: the ion trap comprises an ion trap front cover, an ion trap rear cover and an ion trap electrode, wherein an opening is formed in the middle of the ion trap front cover and is opposite to the quadrupole rod, and an opening is formed in the middle of the ion trap rear cover and is respectively connected with a buffer gas channel, a reaction gas II channel and a reaction gas III channel;

the detector is used for capturing ions ejected from the ion trap;

the cooler is used for reducing the temperature to remove water and impurity gases.

2. The laser sputtering ultrasonic molecular beam carrier ion source mass spectrometry device as claimed in claim 1, wherein a liquid nitrogen tank is placed above the rear cavity for placing liquid nitrogen, and when the device works, impurities in the cavity are frozen by the cooling tank to remove the impurities in the cavity; the front cavity and the back cavity are respectively connected with a set of mechanical pump and molecular pump system, the mechanical pump provides a front stage vacuum of 0.1-10Pa, the molecular pump system provides a high vacuum, and the air pressure is 0.5-10 multiplied by 10 when the pump works^-4Pa。

3. The laser sputtering ultrasonic molecular beam source-ion trap mass spectrum device according to claim 2, wherein the distance between the liquid nitrogen tank and the ion trap is not less than 15 mm.

4. The method for operating a laser sputtering ultrasonic molecular beam source-ion trap mass spectrometry device according to claim 1 or 2, characterized by the specific steps of:

(1) generating laser by a laser, wherein the laser energy is 2-20mJ, and the laser bombards a target material through a laser pore channel on an ion source block to generate plasma; the target material is driven by the motor to continuously rotate so as to improve the signal stability; the carrier gas is introduced through a carrier gas pipeline under the control of a first electromagnetic pulse valve; the carrier gas carries the plasma body to fly into the fast flow tube by the connecting tube with smaller inner diameter, because of the function of ultrasonic expansion, cool and form the ion; reaction gas I is introduced into the rapid flow pipe from the small hole through a second electromagnetic pulse valve; the ions enter an ion introduction area after reacting with the reaction gas I; generating ion species with different proportions by controlling sputtering target material components and gas components;

(2) in the ion introducing area, in the initial state, the first and the second sheet electrodes are at zero potential, when the gas carrying the ions flies out of the fast flow tube and flies to the space between the first sheet electrode and the second sheet electrode of the ion introducing area, the first channel of the pulse electric field generator applies voltage on the first sheet electrode, wherein, positive ions apply positive voltage, negative ions apply negative voltage; the flying direction of the ions is changed and the ions are sent into the cone; the voltage applied by the pulse electric field generator is +/-10-40V, the pulse width is 10-50 mus, the frequency of the applied pulse voltage is greatly faster than the frequency of the ion source pulse sputtering laser, and the number of pulse square waves is 10-30;

the gas of the ions enters the quadrupole rod system through the pore canal of the cone, and is sent into the ion trap system after the mass of the ions is selected by the quadrupole rod system;

(3) when ions fly out of the quadrupole rods, the ion trap front cover applies a voltage opposite to the electrical property of the ions through a second channel of the pulsed electric field generator: and +/-10-20V, applying a voltage with the same electrical property as that of the ions through a third channel of the pulsed electric field generator on the back cover of the ion trap: +/-30-200V, applying electrode radio frequency voltage of 0-1000V on an electrode 12 of the ion trap through an ion trap power supply, and continuously inputting buffer gas through a pipeline; ions fly into the ion trap through a hole with the diameter of 0.1-4mm in the middle of the front cover, and are decelerated under the action of the voltage of the back cover of the ion trap, radio frequency on an electrode of the ion trap and buffer gas, so that the ions are trapped; after trapping, the voltage of the front cover of the ion trap is changed to be the same as that of the rear cover of the ion trap, so that ions stay in the ion trap completely; because the buffer gas is continuously introduced, the ions are cooled for 10-30ms in the trap, then the reaction gas II is introduced through the third electromagnetic pulse valve to react with the ions, the reaction gas stays in the ion trap for 20-50ms after the reaction, and most of the reaction gas is discharged; and applying resonance excitation voltage on the ion trap electrode through the ion trap power supply, and continuously increasing the amplitude of the radio frequency voltage, so that ions are sequentially popped out of the trap according to the mass size and are received by the detector to obtain a mass spectrogram.

5. An operating method according to claim 4, wherein for some of the products of the molecular ion reaction of interest, the ion trap power supply applies an isolation sine wave by SWIFT technique, that is, under the action of the auxiliary resonance excitation voltage on the electrodes, the ions in the trap resonate in sequence according to the mass-to-charge ratio, the frequency of the applied AC voltage is lost by a section, the frequency corresponds to the mass-to-charge ratio of the ions to be retained, the single mass ion cannot resonate and remains bound in the trap, and other ions are ejected from the ion trap; then introducing reaction gas III through a fourth electromagnetic pulse valve to react with ions to obtain a mass spectrogram of a secondary reaction; or inert gas is introduced through the fourth electromagnetic pulse valve, ions and the inert gas are collided to induce dissociation, and structural information is obtained through mass analysis of fragment ions.

6. The operating method according to claim 4 or 5, wherein in the step (1) and the step (3), the reaction gas I, the reaction gas II, the reaction gas III have a gas pressure of 0.1 to 1 atm and a pulse width of 180-; the reaction of the ions and the reaction gas I is an ion molecular reaction without the influence of an external electric field, the reaction of the ions and the reaction gas II or the reaction gas III is a molecular ion reaction with the influence of an electric field, and the influence of the electric field on a reaction channel and the reaction speed is researched by comparison.

7. Operating method according to claim 4 or 5, characterised in that it consists in stepsIn the step (1), different proportions of ion species are generated by controlling the sputtering target component and the gas component, wherein the sputtering target component is M or a compound M_xN_yThe gas component is He gas, and is mixed with other reaction gas L to generate ion species containing M, N and L in different proportions.

8. The operating method according to claim 4 or 5, wherein in the step (3), the buffer gas is helium, other rare gas, or nitrogen, and the gas is introduced in an amount of 0.1-10 ml/min.

9. The operation method according to claim 4, wherein the kinetic energy of the ions is controlled by controlling the pulse voltage of the first electrode in the ion introduction region, the ions enter the ion trap after passing through the quadrupole rod mass selection, the ion trap is filled with large-mass collision gas, the collision gas in the ion trap is subjected to collision induced dissociation, the dissociated ions are decelerated by adjusting the voltage of the back cover of the ion trap and are bound by the radio frequency of the ion trap, and then mass analysis is performed, so that the collision induced dissociation experiment with any kinetic energy is realized.

Technical Field

The invention belongs to the technical field of mass spectrometry, and particularly relates to a laser sputtering ultrasonic molecular beam source-ion trap mass spectrometry device and an operation method thereof.

Background

Molecular reaction kinetics is a leading area of research in chemistry. The research of molecular reaction kinetics is to use advanced experimental means to discuss the process and reaction mechanism of some important elementary reactions in chemistry from atomic molecular level, which is very important for the relevant research of physical chemistry.

The mass spectrometer is an analytical instrument for measuring mass-to-charge ratio of substances, is one of the most important scientific instruments in the field of analysis at present, and is widely applied to the fields of industrial production and people life, such as aerospace, national defense safety, medicine, food safety, trace substance detection and the like. In the field of scientific research, particularly in the fields of analytical chemistry and physical chemistry, mass spectrometry-related techniques also play an important role in the analysis of the composition and structure of species, and in the research of gas phase reactions.

In mass spectrometry systems, ion sources are important components, and in each type of ion source at present, it is very difficult to control the generation of highly reactive species of a specific composition. Since many ions have very high activity in the gas phase and are very likely to react with impurities or background, there is a need for an apparatus that synthesizes ions of a specific composition by controlling experimental conditions, avoids the effects of oxygen, nitrogen, water and the like in the air, and studies the reactivity thereof by mass spectrometry.

Quadrupole rods are a commonly used mass spectrometry and mass selection tool, which achieve separation of ions of different mass to charge ratios by the action of an alternating electric field. Ions can oscillate according to the electric field intensity in the environment of the alternating electric field, and only ions with specific mass-to-charge ratio can stably pass through the electric field, so that the purpose of mass selection is realized.

There are many configurations of ion traps, conventional 3D ion traps and linear ion traps such as: a linear ion trap (United States Patent 5,420,425) of some company, and a rectangular ion trap (United States Patent 6,838,666) of some doctor. These ion trap configurations have different advantages and the appropriate ion trap can be selected for different experimental requirements.

The ion trap can realize multiple functions of ion storage, mass selection, reaction, mass analysis and the like. The general working principle is as follows: the ion source generates ions, the ions enter the ion trap after passing through the ion optical system, and the ions are bound in the ion trap after being cooled. For the sine wave driven ion trap, a mass spectrum is obtained by scanning the radio frequency amplitude and by resonance excitation. For the research of ion reaction, only ions with a certain mass-to-charge ratio are left through selective isolation, other unwanted ions are removed from an ion trap, and then reaction gas is introduced to react with the ions, so that the mass spectrum after the reaction is obtained.

An important technique for ion trap mass analyzers is resonance excitation, in which ions bound in an ion trap are subjected to radio frequency voltages to reciprocate within the ion trap, referred to as secular motion. The secular motion of a particular mass ion has a particular frequency, i.e., a secular frequency, denoted by ω. The secular frequency of the ions is related to the mass-to-charge ratio of the ions themselves, as well as to the frequency omega of the rf voltage applied to the ring electrodes, the geometry of the trap, and other factors. There is a relationship between ω and Ω as follows:

ω _n = (n+ β/2) Ω 0 ≤ n ≤ ∞

when the ion trap is operating, it is believed that the higher order frequencies are of minimal composition, i.e.n=0, then:

ω _n = βΩ/2

in the resonance excitation technique, a radio frequency voltage, referred to as an auxiliary AC voltage, denoted by AC, is applied simultaneously to two electrodes of the ion trap. When the frequency of the AC is close to the secular frequency of ions with a certain mass number, the ions resonate, the motion track is intensified in the direction of the end cover electrode, a specific AC voltage amplitude is selected, and the ions are ejected from the small holes on the end cover electrode and detected by the detector. Under the unstable scanning mode of mass selection, along with the continuous increase of the amplitude of the radio frequency voltage, the ions in the trap sequentially reach resonance points from small to large according to the mass-to-charge ratio, and the ions are sequentially ejected from the trap.

The mass selective isolation of ions currently and generally uses the swift (stored wave form inverter) technique to perform a long-term motion on ions in a quadrupole ion trap with a certain structure, wherein the ions in the trap are subjected to an applied radio frequency voltage, the frequency of the long-term frequency is related to the frequency of the radio frequency voltage and the mass-to-charge ratio of the ions, and for a sine wave driven ion trap, the frequency of the radio frequency voltage is fixed and unchanged, so that the long-term frequency of the ions is only related to the mass-to-charge ratio of the ions, and the mass selective isolation of the ions uses this characteristic, and under the effect of an auxiliary resonance excitation voltage (AC), the ions in the trap sequentially resonate according to the mass-to-charge ratio, and when the frequency of the applied AC voltage is deficient by a section (frequnchech), the ions with the mass-to-charge ratio corresponding to the section of frequency cannot resonate and are still bound in the trap. By setting a specific AC frequency defect range, isolation of ions of a specific mass-to-charge ratio, i.e., mass selective isolation, can be achieved.

Disclosure of Invention

The invention aims to provide a laser sputtering ultrasonic molecular beam carrier ion source-ion trap mass spectrum device for simply and efficiently researching gas-phase species reaction and an operation method thereof.

The invention provides a laser sputtering ultrasonic molecular beam carrier ion source mass spectrum device, which is shown in figure 1 and comprises: the ion source part, the ion introducing area, the separating cone, the quadrupole rod system, the ion trap system, the detector and the cooler; wherein:

the ion source section includes: an ion source block 1 with any shape, wherein the ion source block 1 is provided with a laser pore canal with the diameter of 0.1-5mm and a carrier gas pipeline which is vertical to the laser pore canal and has the inner diameter of 0.1-5 mm; the target 3 is positioned beside the ion source block 1 and is opposite to the laser channel, and the target 3 is driven by a motor to rotate continuously (can rotate at any angle according to requirements); the laser 2 bombards the target 3 through a laser pore channel on the metal block; the carrier gas 4 is introduced into a carrier gas pipeline through a first electromagnetic pulse valve (see figure 2); the outlet of the carrier gas pipeline is connected with a rapid flow pipe 5 through a connecting pipe, and the rapid flow pipe 5 is a cylinder with the length of 10-150mm and the inner diameter of 0.3-6 mm; a small hole is formed in the middle of the rapid flow pipe 5, and reaction gas I6 is introduced through a second electromagnetic pulse valve (shown in figure 2);

the ion introducing area part is vertical to the direction of the ion source, the ion introducing area part comprises three electrodes, the thickness of each electrode is 0.1-10mm, the first electrode is a rectangular metal sheet, the second electrode and the third electrode are rectangular metal sheets with a square groove in the middle, and a welded metal mesh is arranged in the square groove;

a hole with the diameter of 0.1-10mm is formed in the middle of the cone 8 and is horn-shaped, and the space is divided into a front cavity and a rear cavity; the ion source part and the ion leading-out area part are positioned in the front cavity, and the quadrupole rod and the ion trap system are positioned in the rear cavity;

the quadrupole rod system 9 is arranged in the cavity behind the cone 8 and is opposite to the cone 8, and the quadrupole rods are used for allowing the ion selective mass to pass through or not to pass through; then sending the ion beam into an ion trap system;

the ion trap system includes: the ion trap comprises an ion trap front cover 10, an ion trap rear cover 11 and an ion trap electrode 12, wherein an opening is formed in the middle of the ion trap front cover 10 and is opposite to a quadrupole rod, and an opening is formed in the middle of the ion trap rear cover 11 and is respectively connected with a channel of a buffer gas 13, a channel of a reaction gas II14 and a channel of a reaction gas III 15;

the detector 16 is for capturing ions ejected from the ion trap;

the cooler 17 is used for reducing the temperature to remove impurity gases such as water, carbon dioxide and the like.

The operation process of the device comprises the following steps: the laser device generates laser 2 (the generation energy is 2-20 mJ), and the laser bombards the target 3 through a laser pore channel on the ion source block 1 to generate plasma; the target 3 is driven by a motor to continuously rotate so as to improve the signal stability; a carrier gas 4 is introduced through a carrier gas pipeline under the control of the electromagnetic pulse valve I; the carrier gas carries the plasma to fly into the rapid flow tube 5 by a connecting tube with smaller inner diameter, and the plasma is cooled and forms ions due to the effect of ultrasonic expansion; reaction gas I is introduced from the small hole through the electromagnetic pulse valve II (reverse)The reaction gas I is generally methane, carbon monoxide and other gases, the gas pressure is 0.1 to 1 atmosphere, and the pulse width is 180-; the ions enter an ion introduction area after reacting with the reaction gas I; by controlling the sputtering target composition (e.g. metal target M or compound M)_xN_yEtc.) and gas components (typically He gas mixed with other reactant gases L) may produce ionic species containing M, N and L in different proportions.

In the ion introduction region 7, in the initial state, the first and second sheet electrodes are at zero potential, when the gas carrying ions flies out of the fast flow tube 5 and flies to the space between the first sheet electrode and the second sheet electrode of the ion introduction region, the first channel (see fig. 2) of the pulsed electric field generator applies voltage (positive ions plus positive voltage, negative ions plus negative voltage) to the first sheet electrode, so that the ions change the flight direction and are sent into the cone 8; the voltage applied by the pulse electric field generator is +/-10-40V, the pulse width is 10-50 mus, the frequency of the applied pulse voltage is greatly faster than that of the ion source pulse sputtering laser, and the number of pulse square waves is 10-30.

The gas carrying the ions enters the quadrupole rod system through the pore canal of the cone 8, and is sent to the ion trap system after the mass selection of the ions by the quadrupole rod system.

When ions fly out of the quadrupole, a voltage (10-20V) opposite to the electrical property of the ions is applied to the front cover 10 of the ion trap through a second channel (shown in figure 2) of the pulse electric field generator, a voltage (30-40V) same as the electrical property of the ions is applied to the rear cover of the ion trap through a third channel (shown in figure 2) of the pulse electric field generator, an electrode radio frequency (voltage is 0-1000V according to the ion quality) is applied to an electrode 12 of the ion trap through an ion trap power supply (shown in figure 2), and meanwhile, buffer gas 13 is continuously input through a pipeline (helium, other rare gases or nitrogen can be used, the gas input amount is 0.1-10ml/min, and the gas input amount is 0.1-10 ml/min); ions fly into the ion trap through a hole with the diameter of 0.1-4mm in the middle of the front cover 10, and are decelerated under the action of the voltage of the ion trap rear cover 11, the radio-frequency voltage of the ion trap electrode 12 and the buffer gas 13, so that the ions are trapped; after ion trapping, the voltage of the front cover 10 of the ion trap is changed to be the same as that of the rear cover 11 of the ion trap, so that ions are completely stayed in the ion trap; because the buffer gas 13 is continuously introduced, the ions are cooled for 10-30ms after the trap, then the electromagnetic pulse valve III (3 in figure 2) is introduced into the reaction gas II14 (generally methane, carbon monoxide and other gases, the gas pressure is 0.05-0.5 atmospheric pressure, the pulse width is 180-; a resonance excitation voltage (fig. 2) is applied to the electrodes by the ion trap power supply, and the amplitude of the rf voltage is increased continuously, so that ions are ejected from the trap in sequence according to their mass and received by the detector 16 to obtain a mass spectrum.

For some products of interested molecular ion reaction, an ion trap power supply can apply an isolation sine wave (fig. 2) by using a SWIFT technology, that is, under the action of an auxiliary resonance excitation voltage on an electrode, ions in the trap sequentially resonate according to the mass-to-charge ratio, the frequency of an applied AC voltage is deficient by a section (frequency) corresponding to the mass-to-charge ratio of ions to be retained, the single mass ion cannot resonate, is still bound in the trap, and other ions are discharged out of the ion trap (see background introduction); then reaction gas III 15 is introduced through an electromagnetic pulse valve IV (figure 2) to react with ions, and a mass spectrogram of secondary reaction is obtained. And inert gas such as xenon (Xe) can be introduced through the electromagnetic pulse valve, ions and the inert gas are collided and induced to be dissociated, and structural information is obtained through mass analysis of fragment ions.

The reaction gas I, the reaction gas II and the reaction gas III have the gas pressure of 0.1 to 1 atmosphere and the pulse width of 180-; the reaction of the ions and the reaction gas I is an ion molecular reaction without the influence of an external electric field, the reaction of the ions and the reaction gas II or the reaction gas III is a molecular ion reaction with the influence of an electric field, and the influence of the electric field on a reaction channel and the reaction speed is researched by comparison.

The kinetic energy of the ions is controlled by controlling the pulse voltage of the first electrode of the ion introducing area 7, the ions enter the ion trap after mass selection through the quadrupole rods, a certain amount of large-mass collision gas such as xenon (Xe) is introduced into the ion trap, collision induced dissociation occurs in the collision gas in the ion trap, the dissociated ions are decelerated by adjusting the voltage of the ion trap rear cover 10 and are bound by the radio frequency of the ion trap, and then mass analysis is performed. Because the voltage of the lead-in area can be adjusted at will, the invention can realize the collision induced dissociation with any kinetic energy.

In the invention, the ion trap is any two-dimensional linear ion, three-dimensional ion trap or other ion trap mass analyzer in any shape.

In the invention, a laser switch, a carrier gas and four reaction gas sample introduction electromagnetic pulse valves, three paths of ion introduction pulse voltages, electrode radio frequencies of an ion trap, a front cover and a rear cover of the ion trap and a resonance excitation circuit are controlled by a master controller (figure 2).

In the device, a liquid nitrogen tank is arranged above the rear cavity, and liquid nitrogen is put into the device when the device works, so that impurities such as water in the cavity are frozen by the cooling tank, and the impurities in the cavity are removed. The front cavity and the back cavity are respectively connected with a set of mechanical pump and molecular pump system, the mechanical pump provides a front stage vacuum of 0.1-10Pa, the molecular pump system provides a high vacuum, and the air pressure is 0.5-10 multiplied by 10 when the pump works^-4Pa；

The liquid nitrogen tank can be arranged according to equipment, and the distance between the liquid nitrogen tank and the ion trap is not less than 15 mm.

The invention has the following effects: the laser sputtering ultrasonic molecular beam ion source is utilized to synthesize some high-activity gas-phase ions by regulating and controlling target material components and carrier gas components, and the structure and reaction of the ions are analyzed by fully utilizing the characteristic that an ion trap is used for tandem mass spectrometry.

Drawings

Fig. 1 is a schematic structural diagram of a laser sputtering ultrasonic molecular beam ion source-ion trap mass spectrometer device in embodiments 1 and 2 of the present invention.

Fig. 2 is a schematic timing control diagram of the laser sputtering ultrasonic molecular beam ion source-ion trap mass spectrometer apparatus in embodiments 1 and 2 of the present invention.

FIG. 3 is a mass spectrum of an ionic molecule reaction of example 1 of the present invention.

FIG. 4 is a mass spectrum of collision induced dissociation in example 2 of the present invention.

Reference numbers in the figures: 1 is an ion source block, 2 is laser, 3 is a target material, 4 is a carrier gas, 5 is a rapid flow tube, 6 is a reaction gas I, 7 is an ion introduction region, 8 is a cone (skimmer), 9 is a quadrupole rod system, 10 is an ion trap front cover, 11 is an ion trap rear cover, 12 is an ion trap electrode, 13 is buffer gas, 14 is a reaction gas II, 15 is a reaction gas III, 16 is a detector, and 17 is a cooler.

Detailed Description

The present invention will be further described with reference to the accompanying drawings, but the present invention is not limited to the following examples.