阅读说明：本技术 一种长效灭菌剂的制备方法 (Preparation method of long-acting sterilizing agent ) 是由 钟洁龙 洪铭杰 周建兰 于 2019-09-27 设计创作，主要内容包括：本发明公开了一种长效灭菌剂的制备方法,按如下步骤进行：S1,取二氧化氯母体、缓冲剂与水进行混合,并搅拌至二氧化氯母体完全溶解,形成二氧化氯母体溶液；S2,将激活剂加入所述二氧化氯母体溶液中搅拌反应10～15分钟；S3,加入催化剂,继续反应至第80～100分钟时加入二次激活剂进行二阶反应,继续反应至第170～190分钟时,再加入二次激活剂进行三阶反应,其中,上述原料的重量百分比含量范围如下：二氧化氯母体10%～25%；缓冲剂1%～10%；激活剂5%～15%；催化剂0%～6%；二次激活剂0.02%～0.08%；余量为水。本发明具有灭菌效果佳；存放稳定性佳；灭菌效果持续长久；产生的二氧化氯纯度高；绿色环保,制备成本低等优点。(The invention discloses a preparation method of a long-acting sterilizing agent, which comprises the following steps: s1, mixing the chlorine dioxide parent substance, the buffering agent and water, and stirring until the chlorine dioxide parent substance is completely dissolved to form a chlorine dioxide parent substance solution; s2, adding an activator into the chlorine dioxide parent solution, and stirring and reacting for 10-15 minutes; s3, adding a catalyst, continuing to react for 80-100 minutes, adding a secondary activator to perform a second-order reaction, continuing to react for 170-190 minutes, and then adding the secondary activator to perform a third-order reaction, wherein the weight percentage content ranges of the raw materials are as follows: 10 to 25 percent of chlorine dioxide parent substance; 1% -10% of buffering agent; 5 to 15 percent of activating agent; 0 to 6 percent of catalyst; 0.02 to 0.08 percent of secondary activator; the balance being water. The invention has good sterilization effect; the storage stability is good; the sterilization effect lasts for a long time; the purity of the generated chlorine dioxide is high; green and environment-friendly, low preparation cost and the like.)

1. The preparation method of the long-acting sterilizing agent is characterized by comprising the following steps of:

s1, mixing the chlorine dioxide parent substance, the buffering agent and water, and stirring until the chlorine dioxide parent substance is completely dissolved to form a chlorine dioxide parent substance solution;

s2, adding an activator into the chlorine dioxide parent solution, and stirring and reacting for 10-15 minutes;

s3, adding a catalyst, continuing to react for 80-100 minutes, adding a secondary activator to perform a second-order reaction, continuing to react for 170-190 minutes, and then adding the secondary activator to perform a third-order reaction;

wherein, the weight percentage content ranges of the raw materials are as follows:

10 to 25 percent of chlorine dioxide parent substance

1 to 10 percent of buffering agent

5 to 15 percent of activating agent

0 to 6 percent of catalyst

0.02 to 0.08 percent of secondary activator

The balance being water.

2. The preparation method of the long-acting sterilizing agent as claimed in claim 1, wherein the weight percentage of each raw material is as follows:

12 to 23 percent of chlorine dioxide parent substance

3 to 8 percent of buffering agent

7 to 12 percent of activating agent

0.5 to 3 percent of catalyst

0.04 to 0.06 percent of secondary activator

The balance being water.

3. The preparation method of the long-acting sterilizing agent as claimed in claim 2, wherein the weight percentage of each raw material is as follows:

20 percent of chlorine dioxide parent substance

Buffer 5%

10 percent of activating agent

Catalyst 3%

0.06 percent of secondary activator

The balance being water.

4. The method as claimed in any one of claims 1 to 3, wherein the amount of the second activator added in the second reaction is 30-50% of the total weight of the second activator.

5. The method of any one of claims 1-3, wherein the chlorine dioxide precursor is any one of sodium chlorate or sodium chlorite.

6. A method as claimed in any one of claims 1 to 3, wherein the buffer is a mixture of disodium hydrogen phosphate and citric acid in a ratio of 1:2 to 3: 4.

7. The method of any of claims 1-3, wherein the activator is one or more of sorbic acid, benzoic acid, citric acid, oxalic acid, or sodium hypochlorite.

8. The method of any of claims 1-3, wherein the catalyst is sodium tetrachloropalladate.

9. The method for preparing the long-acting sterilizing agent as claimed in any one of claims 1 to 3, wherein the secondary activating agent is one or a mixture of nano-silicone and inorganic silicone.

Technical Field

The invention relates to a bactericide, in particular to a preparation method of a long-acting bactericide.

Background

The chlorine dioxide sterilizing agent is an internationally recognized sterilizing agent, can be used for sterilizing in medical sanitation and food processing, and in the aspects of environment, drinking water, industrial circulation, sewage treatment and the like, and is an internationally recognized most ideal updating product of a chlorine series disinfectant.

The existing method for preparing chlorine dioxide has low activation rate, generates by-products such as chlorate, chlorite, chlorine and the like besides chlorine dioxide, causes the concentration of the chlorine dioxide in the product to be lower than 30 percent, generates a chlorine dioxide aqueous solution with extremely poor stability, is easy to dissipate and has disproportionation reaction, causes the concentration of the chlorine dioxide in the chlorine dioxide aqueous solution to be rapidly reduced, seriously influences the effectiveness of the product, has short storage time, can only be prepared at present and used at present, and has poor use convenience.

In order to solve the problems, the development of a preparation method of a long-acting bactericide which can improve the concentration of chlorine dioxide, has good stability, long storage time, long effective time and good sterilization effect is urgently needed.

Disclosure of Invention

The invention provides a preparation method of a long-acting sterilizing agent, which solves the problems of low concentration, long stability, short storage time, short effective time and poor sterilizing effect of chlorine dioxide prepared by the prior art.

In order to solve the technical problems, the invention provides the following technical scheme:

the preparation method of the long-acting bactericide comprises the following steps: s1, mixing the chlorine dioxide parent substance, the buffering agent and water, and stirring until the chlorine dioxide parent substance is completely dissolved to form a chlorine dioxide parent substance solution;

s2, adding an activator into the chlorine dioxide parent solution, and stirring and reacting for 10-15 minutes;

and S3, adding a catalyst, continuing to react for 80-100 minutes, adding a secondary activator to perform a second-order reaction, continuing to react for 170-190 minutes, and then adding the secondary activator to perform a third-order reaction.

Wherein, the weight percentage content ranges of the raw materials are as follows:

10 to 25 percent of chlorine dioxide parent substance

1 to 10 percent of buffering agent

5 to 15 percent of activating agent

0 to 6 percent of catalyst

0.02 to 0.08 percent of secondary activator

The balance being water.

The invention uses the activator to react with the chlorine dioxide parent body to generate chlorine dioxide, and accelerates the reaction process by adding the catalyst to realize the rapid generation and release of chlorine dioxide, the buffer is added to improve the stability of chlorine dioxide in the solution and ensure that the concentration of chlorine dioxide meets the sterilization requirement, in order to further improve the electronic stability in the reaction process, the secondary activator is added in 80-100 minutes of the reaction process, the secondary activator is further explained to be a conductive material to improve the activation degree of chemical reaction, ensure that the chemical electromotive force is in an active state to generate high activation rate, and simultaneously improve the stability of reaction electrons to realize the long-time stable reaction to generate chlorine dioxide, and the chlorine dioxide is not easy to generate disproportionation reaction in the generation process, and reduces the generation of byproducts such as chlorate, chlorite, chlorine and the like, thereby improving the concentration of chlorine dioxide in, ensuring the sterilization effect.

Further, the weight percentage of each raw material is as follows:

12 to 23 percent of chlorine dioxide parent substance

3 to 8 percent of buffering agent

7 to 12 percent of activating agent

0.5 to 3 percent of catalyst

0.04 to 0.06 percent of secondary activator

The balance being water.

The chlorine dioxide sterilizing agent prepared in the proportioning range has good stability, and due to the addition of the secondary activator which is a conductive material, the electronic stability in the chemical reaction process of the chlorine dioxide is improved, the chemical potential is ensured to be in an active state, the activation degree is improved, the disproportionation reaction of the chlorine dioxide is effectively avoided, the concentration is reduced, the stability of the prepared sterilizing agent solution is improved, and the concentration of the chlorine dioxide is ensured.

Further, the weight percentage of each raw material is as follows:

20 percent of chlorine dioxide parent substance

Buffer 5%

10 percent of activating agent

Catalyst 3%

0.06 percent of secondary activator

The balance being water.

The chlorine dioxide sterilizing agent prepared by the materials according to the proportion is good in stability, and due to the fact that the secondary activator is added and is a conductive material, the electronic stability of chlorine dioxide in the chemical reaction process is improved, chemical potential is enabled to be in an active state, high activation rate is generated, activation degree is improved, the phenomenon that the concentration of chlorine dioxide is reduced due to disproportionation reaction is effectively avoided, the stability of the prepared sterilizing agent solution is improved, and the concentration of chlorine dioxide is guaranteed.

Further, the addition amount of the secondary activator in the second-order reaction accounts for 30-50% of the total addition weight of the secondary activator. When the reaction is about 1/3, the secondary activator is added to effectively improve the electronic stability, reduce the disproportionation reaction of the generated chlorine dioxide, improve the activation rate and ensure that the chlorine dioxide parent fully reacts to generate the chlorine dioxide, and the rest secondary activator is added in the third-order reaction to improve the electronic stability, so that the disproportionation reaction of the chlorine dioxide is not easy to generate, thereby improving the solution stability of the chlorine dioxide.

Further, the chlorine dioxide parent body is any one of sodium chlorate or sodium chlorite. The sodium chlorate or sodium chlorite is easy to purchase and obtain, the price is low, and the purity of the chlorine dioxide obtained by the reaction is high.

Further, the buffer is a mixture of disodium hydrogen phosphate and citric acid, and the ratio of the disodium hydrogen phosphate to the citric acid is 1: 2-3: 4. The buffer provides a stable solution environment for the chlorine dioxide, and improves the solution stability of the chlorine dioxide.

Further, the activating agent is one or more of sorbic acid, benzoic acid, citric acid, oxalic acid or sodium hypochlorite. The components as an activator have good chemical stability and react with chlorine dioxide parent substances to generate chlorine dioxide.

Further, the catalyst is sodium tetrachloropalladate. The sodium tetrachloropalladate is used as a catalyst to effectively improve the reaction speed and quickly obtain the chlorine dioxide.

Further, the secondary activator is any one or mixture of two of nano organic silicon and inorganic silicon.

Compared with the prior art, the invention has the beneficial technical effects that:

firstly, the sterilization effect is good; the sterilizing agent prepared by the invention takes chlorine dioxide as a main sterilizing component, can effectively kill harmful bacteria such as escherichia coli, staphylococcus aureus and the like, and has good sterilizing effect;

secondly, the storage stability is good; according to the invention, the conductive material is added to carry out the second-order reaction and the third-order reaction, so that the electronic stability is improved through the conductive material, and the occurrence of disproportionation reaction of chlorine dioxide is reduced, thereby improving the stability of chlorine dioxide in the solution and ensuring better storage stability;

thirdly, the concentration of chlorine dioxide is high and harmful substances are less; the invention accelerates the generation speed of chlorine dioxide by adding a catalyst, realizes the rapid release of chlorine dioxide, simultaneously enables the chemical electromotive force to be excited in the second-order reaction and the third-order reaction by adding a secondary activation material with conductive performance, enables the secondary activation material to be in an active state all the time, ensures that materials are fully reacted to generate chlorine dioxide, reduces the generation of impurities harmful to human bodies, such as chlorite, chlorate and the like, improves the purity and the concentration of chlorine dioxide, and enables the sterilization effect to last for a long time.

Fourthly, the preparation method is environment-friendly and low in preparation cost; the components used in the invention are all harmless to the environment, can not remain and influence the human health, are easy to purchase and obtain, and have low price, low preparation cost, simple process flow and lower cost, thus being suitable for large-scale production.

Detailed Description