阅读说明：本技术 用于纸基微孔板移液系统的吸纸吸附装置 (Paper suction adsorption device for paper-based microporous plate pipetting system ) 是由 马海波 翟荣安 刘新宇 潘鹏 于 2019-10-17 设计创作，主要内容包括：本发明公开了一种用于纸基微孔板移液系统的吸纸吸附装置,包括平行四边形传动机构、设于平行四边形传动机构上的吸附板以及分别设于平行四边形传动机构两侧的纸基微孔板放置槽和吸纸放置槽；吸纸放置槽中分别设有清洁吸纸放置区和废弃吸纸放置区,清洁吸纸放置区和废弃吸纸放置区之间设有翻板,翻板位于吸纸放置槽的上方并通过一动力源驱动转动；平行四边形传动机构由另一动力源驱动,并带动吸附板在清洁吸纸放置区与纸基微孔板放置槽之间运动。本发明的吸纸吸附装置,能够在实际应用中自动化搬运清洁吸纸,通过吸纸快速地吸取清洗纸基微孔板的废液,并将吸取废液的废弃吸纸自动运输到指定放置区,减少了整个过程的人工干涉。(The invention discloses a paper suction adsorption device for a paper-based microporous plate pipetting system, which comprises a parallelogram transmission mechanism, an adsorption plate arranged on the parallelogram transmission mechanism, and a paper-based microporous plate placing groove and a paper suction placing groove which are respectively arranged at two sides of the parallelogram transmission mechanism; a clean paper suction placing area and a waste paper suction placing area are respectively arranged in the paper suction placing groove, a turning plate is arranged between the clean paper suction placing area and the waste paper suction placing area, and the turning plate is positioned above the paper suction placing groove and is driven to rotate by a power source; the parallelogram transmission mechanism is driven by another power source and drives the adsorption plate to move between the clean paper suction placing area and the paper base micropore plate placing groove. The paper suction adsorption device can automatically convey clean suction paper in practical application, quickly suck the waste liquid for cleaning the paper-based microporous plate through the suction paper, automatically transport the waste suction paper for sucking the waste liquid to a specified placement area, and reduce manual interference in the whole process.)

1. A paper suction adsorption device for a paper-based microporous plate pipetting system is characterized by comprising a parallelogram transmission mechanism, an adsorption plate arranged on the parallelogram transmission mechanism, and a paper-based microporous plate placing groove and a paper suction placing groove which are respectively arranged at two sides of the parallelogram transmission mechanism;

the paper suction placing groove is internally provided with a clean paper suction placing area and a waste paper suction placing area respectively, a turning plate is arranged between the clean paper suction placing area and the waste paper suction placing area, and the turning plate is positioned above the paper suction placing groove and is driven by a power source to rotate between the clean paper suction placing area and the waste paper suction placing area;

the parallelogram transmission mechanism is driven by another power source and drives the adsorption plate to move between the clean paper suction placing area and the paper-based microporous plate placing groove.

2. The paper suction adsorption device for the paper-based microplate pipetting system of claim 1, wherein the power source is a stepper motor.

3. The paper suction adsorption device for the paper-based microplate pipetting system of claim 2, wherein the parallelogram transmission mechanism comprises four connecting rods and a base, each connecting rod is connected with the base through a bearing, and one of the connecting rods is connected with the stepping motor.

4. The paper suction adsorption device for the paper-based microplate pipetting system of claim 1, wherein the adsorption plate is connected with the lower parallelogram transmission mechanism through a bearing.

5. The paper-based microplate pipetting system of claim 1, wherein said plate has a zone below it with rows of wells arranged in a matrix; each row of adsorption holes are mutually connected through holes and communicated with a negative pressure suction nozzle at the edge of the adsorption plate, and the negative pressure suction nozzle is used for being connected with an external negative pressure generating device.

6. The paper-absorbing adsorption device for the paper-based microplate pipetting system of claim 5, wherein 6 rows of adsorption holes are arranged in the adsorption zone, 11 adsorption holes are arranged in each row, and the adsorption holes are arranged along the width direction of the adsorption plate.

7. The paper-absorbing adsorption device for paper-based microplate pipetting systems of claim 6, wherein the length and width of the adsorption zone are each 25mm larger than a standard plastic 96-well microplate.

8. The paper-absorbing adsorption device for the paper-based microplate pipetting system of claim 1, wherein the length and width of the clean paper-absorbing placement area and the waste paper-absorbing placement area are both the same as the length and width of the paper-absorbing and are 10mm larger than the standard plastic 96-well microplate.

9. The paper suction adsorption device for the paper-based microplate pipetting system of claim 1, wherein the size of the flap is the same as that of the clean suction placement area, and one end of the flap is connected with a stepping motor.

10. The paper suction adsorption device for paper-based microplate pipetting system of claim 1, wherein one side of the flap has an isolation region consisting of a plurality of hemispherical solid dots.

Technical Field

The invention relates to the technical field of biochemical analysis, in particular to a paper absorption adsorption device for a paper-based micropore plate pipetting system.

Background

With the continuous development of medical technology, paper gradually comes into the sight of scientists as a cheap and easily available material. The paper has the advantages of lightness, thinness, low price, easy processing, easy transportation, easy recycling and the like, and different surface properties can be obtained through a printing technology. The cellulose constituting the paper has biocompatibility and is favorable for surface modification. In addition, the porosity of the paper enables the paper to have strong water absorption, so that an additional power system does not need to be arranged on the equipment, the paper can be applied to advection detection, microfluidic equipment and the like, and the paper-based microporous plate can be produced at once.

However, in the process of applying the paper-based microporous plate to disease detection, a cleaning link is often involved, and a method of absorbing waste liquid by using clean suction paper after washing by using a cleaning solution is widely adopted at present. Automation of the detection process is an urgent problem to meet the demand for rapid disease diagnosis and high throughput.

Disclosure of Invention

The technical problem to be solved by the invention is to provide a paper suction adsorption device for a paper-based micropore plate pipetting system, which can automatically carry and clean the paper suction in practical application, quickly suck the waste liquid for cleaning the paper-based micropore plate through the paper suction, automatically transport the waste paper suction for sucking the waste liquid to a specified placement area, and reduce the manual interference in the whole process.

In order to solve the technical problem, the invention provides a paper suction adsorption device for a paper-based microporous plate pipetting system, which comprises a parallelogram transmission mechanism, an adsorption plate arranged on the parallelogram transmission mechanism, and a paper-based microporous plate placing groove and a paper suction placing groove which are respectively arranged at two sides of the parallelogram transmission mechanism;

the paper suction placing groove is internally provided with a clean paper suction placing area and a waste paper suction placing area respectively, a turning plate is arranged between the clean paper suction placing area and the waste paper suction placing area, and the turning plate is positioned above the paper suction placing groove and is driven by a power source to rotate between the clean paper suction placing area and the waste paper suction placing area;

the parallelogram transmission mechanism is driven by another power source and drives the adsorption plate to move between the clean paper suction placing area and the paper-based microporous plate placing groove.

The adsorption plate is driven by the parallelogram transmission mechanism, so that compared with mechanisms such as a mechanical arm and the like, the adsorption plate has a simpler structure, the action of conveying and cleaning the paper is simplified, and the whole process is easier to control.

Further, the power source is a stepping motor.

Furthermore, the parallelogram transmission mechanism comprises four connecting rods and a base, each connecting rod is connected with the base through a bearing, and one of the connecting rods is connected with the stepping motor.

Furthermore, the adsorption plate is connected with a parallelogram transmission mechanism below the adsorption plate through a bearing.

Furthermore, an adsorption area is arranged below the adsorption plate, and a plurality of rows of adsorption holes arranged in a matrix form are arranged in the adsorption area; each row of adsorption holes are mutually connected through holes and communicated with a negative pressure suction nozzle at the edge of the adsorption plate, and the negative pressure suction nozzle is used for being connected with an external negative pressure generating device.

Furthermore, be equipped with 6 rows of adsorption holes in the adsorption zone, every row is provided with 11 adsorption holes, just the adsorption hole is arranged along the width direction of adsorption plate.

Further, the length and width of the adsorption zone are each 25mm larger than standard plastic 96-well microplates.

Furthermore, the length and width of the clean paper suction placing area and the waste paper suction placing area are the same as the length and width of the paper suction, and are respectively 10mm larger than that of a standard plastic 96-hole microporous plate.

Further, the size of the turning plate is the same as that of the cleaning paper suction placing area, and one end of the turning plate is connected with the stepping motor.

Furthermore, an isolation area consisting of a plurality of hemispherical solid points is arranged on one side surface of the turning plate.

The invention has the beneficial effects that:

the paper suction adsorption device for the paper-based micropore plate pipetting system can automatically carry clean suction paper in practical application, quickly suck waste liquid through the suction paper, automatically transport the waste suction paper sucking the waste liquid to a specified placement area, and reduce manual interference in the whole process. In addition, inhale paper and place a plurality of clean paper of inhaling in the district that can prestore, improved whole liquid-transfering system's degree of automation.

Drawings

FIG. 1 is a side view of an embodiment of a paper suction device of the present invention;

FIG. 2 is a top view of the suction paper adsorption device of FIG. 1;

FIG. 3 is a schematic view of the structure of the adsorption plate;

wherein: 1. an adsorption plate; 2. a parallelogram drive mechanism; 3. turning over a plate; 4. a paper suction placing groove; 41. a waste paper suction placing area; 42. cleaning a paper suction placing area; 5. a paper-based microporous plate; 51. a paper-based microporous plate placing groove; 6. a first stepper motor; 7. a second stepper motor.

Detailed Description

The present invention is further described below in conjunction with the following figures and specific examples so that those skilled in the art may better understand the present invention and practice it, but the examples are not intended to limit the present invention.