阅读说明：本技术 一种稳定型二氧化氯泡腾剂及其制备方法 (Stable chlorine dioxide effervescent agent and preparation method thereof ) 是由 成兰兴 赵增兵 赵怡丽 谢存明 谢云曼 陈波 张圆春 杨舒程 谷中鸣 匡文辉 张 于 2019-09-19 设计创作，主要内容包括：一种稳定型二氧化氯泡腾剂及其制备方法,其特征在于：所述稳定型二氧化氯泡腾剂是氯酸钠,无水亚硫酸氢钠、无水硫酸氢钠、无水硫酸钠、无水硫酸铜、无水碳酸钠混合制备而成,其质量比为5~20∶3~8∶5~12∶25~40：1~3：1。制备方法步骤如下：a、将氯酸钠、无水硫酸钠、无水碳酸钠按质量比混合均匀,在45~60℃温度下真空干燥6-12小时作为A；b、将无水亚硫酸氢钠、无水硫酸氢钠、无水硫酸铜按质量比混合均匀,在45-60℃温度下真空干燥6-12小时作为B；c、将步骤a和b中制备好的A和B料在粉体混合机中充分混合均匀,密封包装,干燥阴凉环境中储存。本发明产品中二氧化氯有效含量为8%-12%,本发明提供的二氧化氯泡腾剂安全稳定,没有分解爆炸危险,杀菌消毒持续时间长,杀灭率高。(A stable chlorine dioxide effervescent agent is characterized by being prepared by mixing sodium chlorate, anhydrous sodium hydrogen sulfite, anhydrous sodium hydrogen sulfate, anhydrous sodium sulfate, anhydrous copper sulfate and anhydrous sodium carbonate in a mass ratio of 5 ~ 20: 3 ~ 8: 5 ~ 12: 25 ~ 40: 1 ~ 3: 1, and the preparation method comprises the following steps of uniformly mixing sodium chlorate, anhydrous sodium sulfate and anhydrous sodium carbonate in a mass ratio, performing vacuum drying at 45 ~ 60 ℃ for 6 ~ 12 hours to obtain A, uniformly mixing anhydrous sodium hydrogen sulfite, anhydrous sodium hydrogen sulfate and anhydrous copper sulfate in a mass ratio, performing vacuum drying at 45 ~ 60 ℃ for 6 ~ 12 hours to obtain B, and fully mixing the A and B materials prepared in the steps a and B in a powder mixing machine, sealing and packaging, and storing in a dry and cool environment.)

1. the stable chlorine dioxide effervescent agent is characterized by being prepared by mixing sodium chlorate, anhydrous sodium bisulfite, anhydrous sodium bisulfate, anhydrous sodium sulfate, anhydrous copper sulfate and anhydrous sodium carbonate in a mass ratio of 5 ~ 20: 3 ~ 8: 5 ~ 12: 25 ~ 40: 1 ~ 3: 1.

2. a process for preparing the stabilized chlorine dioxide effervescent formulation of claim 1, wherein: the preparation method comprises the following steps:

a. uniformly mixing sodium chlorate, anhydrous sodium sulfate and anhydrous sodium carbonate according to a mass ratio, and performing vacuum drying at the temperature of 45 ~ 60 ℃ for 6 ~ 12 hours to obtain A;

b. Uniformly mixing anhydrous sodium bisulfite, anhydrous sodium bisulfate and anhydrous copper sulfate according to the mass ratio, and performing vacuum drying at the temperature of 45-60 ℃ for 6-12 hours to obtain B;

c. and (c) fully and uniformly mixing the materials A and B prepared in the steps a and B in a powder mixer, sealing and packaging, and storing in a dry and cool environment.

3. The method of claim 2, wherein: the effective content of chlorine dioxide in the stable chlorine dioxide effervescent agent is 8% -12%.

Technical Field

The invention relates to a sterilizing disinfectant, in particular to a stable chlorine dioxide effervescent agent and a preparation method thereof.

Background

Chlorine dioxide is a high-efficiency, nontoxic, rapid and spectral disinfectant, and is a fourth-generation safe and nontoxic green disinfectant recognized internationally. Can kill bacteria, fungi, viruses, spores and other microorganisms, has a disinfection effect superior to that of common hypochlorite, chlorine, glutaraldehyde and other disinfectants, is 8 times of that of chlorine, and does not produce chloralkane and other carcinogenic substances.

The early chlorine dioxide disinfectant mostly leads chlorine dioxide gas into inert solution to form 2-5% solution, but the content is low, the chlorine dioxide can be released only by adding an activating agent when the chlorine dioxide disinfectant is used, the content of the chlorine dioxide can be reduced after the chlorine dioxide disinfectant is stored for a long time, the sterilization and disinfection effect is influenced, and the transportation and storage cost is high. Therefore, the chlorine dioxide solid preparation is popular in the market, and compared with a liquid chlorine dioxide solution, the chlorine dioxide solid preparation has the advantages of simple use and operation, high effective content, convenient transportation and use and the like.

solid chlorine dioxide preparations used in the market at present are all prepared by fully mixing chlorite serving as a chlorine dioxide source, organic acid or inorganic strong acid weak base salt serving as an activating agent, sodium carbonate serving as an effervescent agent and magnesium sulfate or calcium chloride serving as a drying and isolating agent to prepare powder or tablets for use. However, chlorite is very easy to decompose under the moist and weak acid conditions, so that the effective content is easy to gradually reduce in the production, storage and transportation processes, which affects the sterilization and disinfection effect, and more importantly, the concentration of chlorine dioxide gas generated by chlorite decomposition reaches a certain limit, which can cause potential safety hazards such as explosion hazard.

Chinese patent CN101695305A discloses a unitary packaged chlorine dioxide powder, which mainly comprises sodium chlorite, sulfamic acid, sodium bisulfate, magnesium sulfate and sodium dichloroisocyanurate, and the content of the product is 20%. Chinese patent CN101411334 discloses a method for preparing chlorine dioxide disinfectant powder by using sodium chlorite, sodium bisulfate, anhydrous magnesium sulfate and anhydrous sodium carbonate polyethylene glycol as raw materials. However, when the formulation is used and dissolved, when a certain amount of the preparation is added into water, an explosion sound is generated, which is a precursor of chlorine dioxide explosion and is a potential safety hazard, so how to solve the safety problems that the solid preparation of chlorine dioxide is easy to decompose and explode and the like, a stable solid effervescent agent of chlorine dioxide is urgently needed to be found, and the stable solid effervescent agent of chlorine dioxide has important significance for eliminating the potential safety hazard, improving the production and storage stability of products and ensuring the disinfection effect of chlorine dioxide.

Disclosure of Invention

Aiming at the defects in the prior art, the invention provides the preparation method of the chlorine dioxide effervescent agent, which has the advantages of easily available raw materials, low cost, good effect, safety and stability.

The aim of the invention can be achieved by the following technical measures:

the stable chlorine dioxide effervescent agent is prepared by mixing sodium chlorate, anhydrous sodium bisulfite, anhydrous sodium bisulfate, anhydrous sodium sulfate, anhydrous copper sulfate and anhydrous sodium carbonate, wherein the mass ratio of the sodium chlorate to the anhydrous sodium bisulfite to the anhydrous sodium bisulfate to the anhydrous sodium sulfate to the anhydrous copper sulfate to the anhydrous sodium carbonate is 5 ~ 20: 3 ~ 8: 5 ~ 12: 25 ~ 40: 1 ~ 3: 1.

The preparation method comprises the following steps:

a. uniformly mixing sodium chlorate, anhydrous sodium sulfate and anhydrous sodium carbonate according to a mass ratio, and performing vacuum drying at the temperature of 45 ~ 60 ℃ for 6 ~ 12 hours to obtain A;

b. uniformly mixing anhydrous sodium bisulfite, anhydrous sodium bisulfate and anhydrous copper sulfate according to the mass ratio, and performing vacuum drying at the temperature of 45-60 ℃ for 6-12 hours to obtain B;

c. And (c) fully and uniformly mixing the materials A and B prepared in the steps a and B in a powder mixer, sealing and packaging, and storing in a dry and cool environment.

the stable chlorine dioxide effervescent agent has the effective content of chlorine dioxide of 8-12%.

The invention has the following beneficial effects:

the stable chlorine dioxide effervescent agent of the invention generates chlorine dioxide by the oxidation-reduction reaction of A, B raw materials under the existence of catalyst in aqueous solution of oxidant and reducer, therefore, under the dry state, no reaction occurs, the product is safe and stable when not used, and the danger of explosion during the production, storage and transportation of the product is eliminated. The reaction equation is:

2NaClO₃+NaHSO₃+NaHSO₄＝2ClO₂+2Na₂SO₄+H₂O

Sodium chlorate is a strong oxidant, sodium bisulfite is a reducing agent, the sodium chlorate and the sodium bisulfite generate oxidation-reduction reaction under the acidic condition in aqueous solution to generate chlorine dioxide, copper sulfate enters the aqueous solution to form copper ions, the copper ions are used as catalysts of the oxidation-reduction reaction, the reaction can be accelerated, and the chlorine dioxide is rapidly generated to play a role in quickly sterilizing and disinfecting. Meanwhile, the copper sulfate also has the sterilization and disinfection effects and has the synergistic sterilization and disinfection effects with the chlorine dioxide. The addition of sodium carbonate in water solution produces carbon dioxide gas under acidic condition to produce effervescence and to make the powder or tablet disintegrate fast and speed up the reaction.

Detailed Description

The invention will be further described with reference to the following examples: