阅读说明：本技术 2-噻唑甲醛-1-萘席夫碱的结构、制备和用途 (structure, preparation and application of 2-thiazole formaldehyde-1-naphthalene Schiff base ) 是由 谭学杰 刘帅 邢殿香 于 2019-09-30 设计创作，主要内容包括：本发明涉及一种化合物晶体的结构、制备方法及部分性质。这种化合物外观呈黄色片状晶体,熔点为：111.8-112.9℃,分子式C<Sub>15</Sub>H<Sub>11</Sub>N<Sub>3</Sub>S,化学名为：2-((E)-(((E)-萘-1-基亚甲基)亚肼基)甲基)噻唑；该化合物结构详见说明书,具有一定的荧光性质以及抗癌活性。(The invention relates to a structure, a preparation method and partial properties of a compound crystal. This compound appears as yellow plate crystals with a melting point: 111.8-112.9 deg.C, molecular formula C 15 H 11 N 3 s, the chemical name is: 2- ((E) - (((E) -naphthalen-1-ylmethylene) hydrazono) methyl) thiazole; the structure of the compound is detailed in the specification, and the compound has certain fluorescence property and anticancer activity.)

1. a compound which appears as yellow plate crystals having a melting point of: 111.8-112.9 deg.C, molecular formula C₁₅H₁₁N₃S, the chemical name is: 2- ((E) - (((E) -naphthalen-1-ylmethylene) hydrazono) methyl) thiazole, having the structure:

the crystal belongs to monoclinic system, space group is P21/n,β＝92.648(8)°，Z＝4。

2. A method of synthesizing a compound as claimed in claim 1, characterized in that: taking (E) -2- (hydrazono) thiazole and 1-naphthalene-formaldehyde as raw materials, reacting at normal temperature or heating to reflux, and reacting in organic solvents such as methanol/ethanol/acetonitrile/dichloromethane/chloroform/tetrahydrofuran/acetone, and the like, wherein the steps are as follows:

1) Dissolving all (E) -2- (hydrazono) thiazole in an organic solvent, adding 1-naphthalene-formaldehyde according to the mass ratio of 1:4 to 4:1, and stirring or grinding at a certain temperature for reaction for 1-10 h to complete the reaction; if a solid phase reaction is adopted, an organic solvent can be omitted;

2) Filtering, and naturally volatilizing the filtrate to separate out yellow flaky crystals which are target products; if solid phase reaction is adopted, the target product crystal can be obtained by recrystallization with organic solvents such as methanol/ethanol/acetonitrile/dichloromethane/chloroform/tetrahydrofuran/acetone and the like.

3. Use of the compound crystal according to claim 1 in the fields of dyes, organic pigments, optical brighteners, photo-oxidizers, coatings, chemical and biochemical label analysis, solar traps, security labels, drug tracing, fluorescent probes, fluorescence analysis, opto-electronics, photochemical sensors, laser dyes, organic electroluminescent devices, etc., based on its fluorescent properties.

4. Use of a crystal or other pharmaceutically acceptable salt of a compound as claimed in claim 1 for the manufacture of a medicament for the treatment of tumours, wherein: the tumor is lung cancer, malignant melanoma and cervical cancer.