阅读说明：本技术 与非离子结合剂结合的抗微生物非织造湿巾 (Antimicrobial nonwoven wet wipe in combination with nonionic binders ) 是由 J·R·博伊兰 D·萨格尔 于 2017-05-03 设计创作，主要内容包括：一种抗微生物非织造湿巾,其包括：i)与用一种或多种非离子胶体稳定剂和一种或多种非离子表面活性剂稳定的可交联VAE分散体结合的纤维非织造基底,以及ii)吸收在所述非织造基底中的包含一种或多种阳离子消毒剂的水性洗剂。抗微生物非织造湿巾中不存在阴离子表面活性剂。一种制备抗微生物非织造湿巾的方法,包括：a)将包含用一种或多种非离子胶体稳定剂和一种或多种非离子表面活性剂稳定的可交联VAE分散体的第一水性组合物施用于非织造基底上；b)对组合物进行干燥；以及c)将第二水性组合物施用于步骤b)的产物上。第一水性组合物和第二水性组合物中的至少一种包含一种或多种阳离子消毒剂。(An antimicrobial nonwoven wet wipe comprising: i) a fibrous nonwoven substrate in combination with a crosslinkable VAE dispersion stabilized with one or more nonionic colloidal stabilizers and one or more nonionic surfactants, and ii) an aqueous lotion comprising one or more cationic disinfectants absorbed in the nonwoven substrate. Anionic surfactants are not present in the antimicrobial nonwoven wipe. A method of making an antimicrobial nonwoven wet wipe comprising: a) applying a first aqueous composition comprising a crosslinkable VAE dispersion stabilized with one or more nonionic colloidal stabilizers and one or more nonionic surfactants to a nonwoven substrate; b) drying the composition; and c) applying a second aqueous composition to the product of step b). At least one of the first aqueous composition and the second aqueous composition comprises one or more cationic disinfecting agents.)

1. An antimicrobial nonwoven wet wipe comprising:

i) A fibrous nonwoven substrate in combination with a crosslinkable VAE dispersion stabilized with one or more nonionic colloidal stabilizers and one or more nonionic surfactants, and

ii) an aqueous lotion absorbed in the nonwoven substrate comprising one or more cationic disinfecting agents,

Wherein anionic surfactant is not present in the antimicrobial nonwoven wet wipe.

2. the antimicrobial nonwoven wet wipe of claim 1, wherein the one or more nonionic colloidal stabilizers comprises polyvinyl alcohol.

3. The antimicrobial nonwoven wet wipe of claim 1, wherein the one or more nonionic colloidal stabilizers comprises hydroxyethyl cellulose.

4. The antimicrobial nonwoven wet wipe of any one of the preceding claims, wherein the one or more nonionic surfactants comprise ethoxylated acetylenic diols.

5. The antimicrobial nonwoven wet wipe of any one of the preceding claims, wherein the one or more cationic disinfectants comprises a quaternary ammonium disinfectant.

6. the antimicrobial nonwoven wet wipe of any one of the preceding claims, wherein the one or more cationic disinfecting agents comprises benzalkonium chloride.

7. A method of making an antimicrobial nonwoven wet wipe according to any of the preceding claims, the method comprising:

a) Applying a first aqueous composition comprising a crosslinkable VAE dispersion stabilized with one or more nonionic colloidal stabilizers and one or more nonionic surfactants to a nonwoven substrate;

b) Drying the composition; and

c) Applying a second aqueous composition to the product of step b);

Wherein at least one of the first aqueous composition and the second aqueous composition comprises one or more cationic disinfecting agents.

8. the method of claim 7, wherein the first aqueous composition comprises one or more of the cationic disinfectants.

9. The method of claim 7, wherein the second aqueous composition comprises one or more of the cationic disinfectants.

Technical Field

The present invention relates to a nonwoven wet wipe comprising an aqueous antimicrobial lotion, wherein the wet wipe is combined with a nonionic binding agent.

Background

Self-crosslinking dispersing binders used in the airlaid nonwoven industry are generally stabilized with an amount of anionic surfactant. US 5,109,063 discloses a method for preparing vinyl acetate ethylene N-methylolacrylamide (NMA) copolymer emulsions for non-woven binder applications. The emulsifying system consists of a salt of alkyleneoxy poly (ethyleneoxy) sulfate. This type of binder is commonly used in wet wipe applications with lotions that are compatible with the anionic nature of the self-crosslinking binder used to provide integrity to the nonwoven article. US 7,915,184 claims a nonwoven antimicrobial wipe comprising a fibrous nonwoven substrate coated with a mixture of nonionic and cationic binders and subsequently coated with a cationic disinfectant. US 4,449,978 claims a dry nonwoven product which is combined with a copolymer of vinyl acetate, ethylene, NMA and acrylamide stabilized with a non-ionic emulsifier.

US 2002/0183233 a1 discloses that the release of cationic disinfectants is improved by adding a salt to the lotion, thereby improving the antimicrobial nonwoven.

There remains a need for a simple and cost effective way to improve the efficacy of cationic disinfectants in wet wipe compositions.

Disclosure of Invention

The present invention provides an antimicrobial nonwoven wet wipe comprising: i) a fibrous nonwoven substrate in combination with a crosslinkable VAE dispersion stabilized with one or more nonionic colloidal stabilizers and one or more nonionic surfactants; and ii) an aqueous lotion comprising one or more cationic disinfecting agents absorbed in the nonwoven substrate. No anionic surfactant is present in the antimicrobial nonwoven wet wipe.

A method of making an antimicrobial nonwoven wet wipe comprising: a) applying a first aqueous composition comprising a crosslinkable VAE dispersion stabilized with one or more nonionic colloidal stabilizers and one or more nonionic surfactants to a nonwoven substrate; b) drying the composition; and c) applying a second aqueous composition to the product of step b). At least one of the first aqueous composition and the second aqueous composition comprises one or more cationic disinfecting agents.

Detailed Description

The inventors have found that if anionic surfactants are present in the nonwoven wet wipe, the release and therefore the efficacy of cationic disinfectants, such as quaternary ammonium disinfectants, is reduced. Anionic surfactants are commonly used to stabilize vinyl acetate ethylene copolymer (VAE) dispersions for use as nonwoven substrate binders. However, the inventors have found that VAE dispersions non-ionically stabilized with a combination of one or more nonionic surfactants and one or more nonionic protective colloids provide improved cationic disinfectant efficacy in wet wipe compositions compared to anionically stabilized VAE binder dispersions. Thus, the binder composition according to the invention and wet wipes prepared therefrom are free or substantially free of anionic surfactants to avoid interfering with the activity of the cationic disinfectant. Preferably, the antimicrobial nonwoven wet wipe does not include a polymer comprising a plurality of cationic moieties.

The components and methods of making an antimicrobial nonwoven wipe in combination with a nonionic VAE binding agent in accordance with the present invention will now be discussed in detail. Percentages of materials recited herein are by weight unless the context indicates otherwise.

VAE copolymers

Unless otherwise specified, the weight percentages of monomers mentioned herein are based on the total weight of all monomers in the polymerization used to make the VAE copolymer, with the weight percentages of monomers in each case totaling 100%. Similarly, the percentages of monomers in the copolymer are by weight.

the VAE copolymers used as binders according to the present invention comprise polymerized units of vinyl acetate, ethylene, N-methylol functional monomers and (meth) acrylamide, i.e. acrylamide and/or methacrylamide. Vinyl acetate is typically copolymerized in an amount of at least 65 wt%, or at least 70 wt%, and up to 94.5 wt%, or up to 85 wt%. Ethylene is typically copolymerized in an amount of at least 5 wt%, or at least 10 wt%, and up to 30 wt% or up to 20 wt%.

The proportion of N-methylol-functional monomer in the copolymer is generally at least 0.1 wt.%, or at least 0.5 wt.%, 1 wt.%, or 2 wt.%, and generally at most 10.0 wt.%, or at most 8 wt.%, or 5 wt.%, in each case based on the total weight of monomers used for polymerization.

Suitable amounts of N-methylol functional monomer are at least 25 wt.%, or at least 30 wt.%, 35 wt.%, 40 wt.%, 45 wt.%, 50 wt.%, or 55 wt.%, relative to the total amount of N-methylol functional monomer plus (meth) acrylamide. The amount will be at most 85 wt%, or at most 80 wt%, 75 wt%, 70 wt%, 65 wt%, or 60 wt%.

the total amount of N-methylol functional monomer plus (meth) acrylamide present in the copolymer is at least 0.2 wt.%, or at least 0.5 wt.%, 1 wt.%, 3 wt.%, or 5 wt.%, and is at most 5.0 wt.%, or at most 8 wt.%, 10 wt.%, or 15 wt.%.

Suitable exemplary N-methylol functional monomers for preparing the copolymer include N-methylolacrylamide (NMA), N-methylolmethacrylamide, allyl N-methylolcarbamate, and esters of N-methylolacrylamide, N-methylolmethacrylamide, or allyl N-methylolcarbamate. N-methylolacrylamide and N-methylolmethacrylamide are particularly preferred. The N-methylol functional monomer is used in combination with acrylamide and/or methacrylamide, preferably acrylamide. Most preferred are blends of N-methylolacrylamide and acrylamide. Such blends are commercially available, for example as a 48% aqueous solution of NMA and acrylamide in a 1:1 molar ratio, under the trade nameNMA-LF MONOMER (Cytec Industries, Woodland Park, NJ) or as an aqueous solution containing 28% b.w.N-methylolacrylamide and 20% b.w.acrylamide under the trade nameNMA2820 (SNF Floerger, Andrezieux, France). Alternatively, NMA and acrylamide may be added separately to the polymerization feed.

In addition to NMA, other N- (C) s may be included in the VAE copolymer_1-4) Methylol (meth) acrylamide. Ethylenically unsaturated monomers containing cellulose reactive moieties, such as those containing aldehyde, protected aldehyde and glycolic acid moieties, may also be included. Examples include isobutoxymethacrylamide, acrylamidoglycolic acid, acrylamidobutyraldehyde, and the dialkyl acetals of acrylamidobutyraldehyde, wherein the alkyl groups each individually have from 1 to 4 carbon atoms.

Optionally, the range of useful properties of the copolymer in dispersion can be extended by including additional monomers in the VAE copolymer. Generally, suitable comonomers are monomers having a single polymerizable olefinic group. Examples of such comonomers are vinyl esters of carboxylic acids having 3 to 18C atoms. The preferred vinyl ester is vinyl propionateVinyl esters, vinyl butyrate, vinyl 2-ethylhexanoate, vinyl laurate, 1-methylvinyl acetate, vinyl pivalate and vinyl esters of alpha-branched monocarboxylic acids having 9 to 11C atoms, examples being VEOVA9^TMOr VEOVA10^TMEsters (available from Momentive Specialty Chemicals, Houston, TX). Other suitable comonomers include esters of acrylic or methacrylic acid with linear or branched alcohols having 1 to 15C atoms. Exemplary methacrylates or acrylates include methyl acrylate, methyl methacrylate, ethyl acrylate, ethyl methacrylate, propyl acrylate, propyl methacrylate, n-butyl acrylate, n-butyl methacrylate, 2-ethylhexyl acrylate, and norbornyl acrylate. Other suitable comonomers include vinyl halides, such as vinyl chloride, or olefins, such as propylene. Typically, the other comonomer is copolymerized in an amount of 0.5 to 30 wt%, preferably 0.5 to 20 wt%, based on the total weight of monomers used for polymerization.

Optionally, from 0.05 to 10% by weight of further monomers (auxiliary monomers) can additionally be copolymerized in the formation of the dispersion, based on the total weight of the monomers used for the polymerization. The auxiliary monomer comprises a polymerizable alkenyl group and at least one additional functional group. Examples of auxiliary monomers include acrylonitrile and diesters of fumaric and maleic acids, such as diethyl and diisopropyl esters. Typically, there is only one polymerizable olefinic group in each monomer used to prepare the VAE copolymer, although more may be possible in some cases.

On the other hand, ethylenically unsaturated monomers containing carboxylic, sulfonic or phosphoric acid or phosphonic acid groups, their salts or groups which are hydrolyzed to them when used for the preparation of wet wipes according to the invention are generally excluded from the VAE copolymers used as binders for making wet wipes. More generally, any type of polymer that includes any or all of these as monomeric units may be excluded from the wet wipes of the present invention. Specific examples include acrylic acid, methacrylic acid, fumaric acid, maleic anhydride, vinylsulfonic acid, and 2-acrylamido-2-methyl-propanesulfonic acid.

The choice of the monomers or the weight ratio of the monomers is preferably made in such a way that the copolymer generally has a suitable glass transition temperature (Tg). Typically, the Tg is at least-10 ℃, or at least-5 ℃, or at least 0 ℃, and at most +20 ℃, or at most +15 ℃, or at most +10 ℃. The glass transition temperature Tg of the copolymers can be determined in a known manner by Differential Scanning Calorimetry (DSC) according to ASTM D3418-82 as starting temperature with a heating rate of 10K per minute. Tg can also be approximately pre-calculated by the Fox equation. According to Fox t.g., bull.am.physics soc.1,3, page 123 (1956): 1/Tg ═ x1/Tg1+ x2/Tg2+. + xn/Tgn, where xn is the mass fraction of monomer n (% by weight/100) and Tgn is the glass transition temperature in kelvin of the homopolymer of monomer n. The Tg values of the homopolymers are given in Polymer handbook, second edition, J.Wiley & Sons, New York (1975).

Nonionic surfactant

suitable nonionic surfactants, also referred to herein as nonionic emulsifiers, are, for example, acyl, alkyl, oleyl, and alkylaryl ethoxylates. Also suitable are ethoxylated branched or straight-chain fatty alcohols (aliphatic alcohols), which preferably have a degree of ethoxylation of from 3 to 80 ethylene oxide units and a C₆To C₃₆An alkyl group. Other examples include C with a degree of ethoxylation of from 3 to 30 ethylene oxide units₁₃-C₁₅Oxo alcohol ethoxylates, C having a degree of ethoxylation of from 11 to 80 ethylene oxide units₁₆-C₁₈Alcohol ethoxylates, C having a degree of ethoxylation of from 3 to 11 ethylene oxide units₁₀Oxo alcohol ethoxylates, C with a degree of ethoxylation of 3 to 20 ethylene oxides₁₃Oxo alcohol ethoxylates, polyoxyethylene sorbitan monooleate with 20 ethylene oxide groups. Further examples include polyethylene oxide ethers of oleyl alcohol having a degree of ethoxylation of from 4 to 20 ethylene oxide units, and polyethylene oxide ethers of nonylphenol having a degree of ethoxylation of from 4 to 20 ethylene oxide units. Still further examples include copolymers of ethylene oxide and propylene oxide having a minimum ethylene oxide content of at least 10 weight percent.

Preferred emulsificationThe agent being an ethoxylated branched or straight chain aliphatic alcohol, in particular having a degree of ethoxylation of from 3 to 80 ethylene oxide units and a C₈To C₃₆An alkyl group. Preferred nonionic emulsifiers also include C having a degree of ethoxylation of from 3 to 30 ethylene oxide units₁₃-C₁₅Oxo alcohol ethoxylates, and C having a degree of ethoxylation of from 11 to 80 ethylene oxide units₁₆-C₁₈An aliphatic alcohol ethoxylate. Particularly preferred are C with a degree of ethoxylation of from 3 to 30 ethylene oxide units₁₂-C₁₄Aliphatic alcohol ethoxylates, and copolymers of ethylene oxide and propylene oxide having a minimum ethylene oxide content of at least 10% by weight. Preferably, these surfactants do not contain alkylphenol ethoxylate structures and are not endocrine disruptors.

The total amount of emulsifiers is generally from 0.5 to 5% by weight, preferably from 1 to 3% by weight, based in each case on the total weight of the monomers.

Non-ionic protective colloids

One or more nonionic protective colloids are used to stabilize the VAE dispersion during and after the polymerization reaction in which they are formed. Suitable nonionic protective colloids include polyvinyl alcohol (PVOH) and nonionic cellulose derivatives such as hydroxyethyl cellulose, but other materials may be used instead or in addition. Other examples include polyvinylpyrrolidone, PVOH with ethylene oxide or polyethylene oxide substituents, and acetoacetylated PVOH. Additionally, copolymers of PVOH may be used. Examples include ethylene and/or N-vinylpyrrolidone copolymers of vinyl alcohol.

Polyvinyl alcohol is particularly useful. Suitable PVOH includes partially hydrolysed polyvinyl alcohols having a degree of hydrolysis of from 80 mol% to 99 mol%, preferably from 85 mol% to 99 mol%, and a viscosity in a 4% strength aqueous solution of from 1mPas to 30mPas, preferably from 3mPas to 6mPas (homepler viscosity, determined at 20 ℃ according to DIN 53015). Most preferred are polyvinyl alcohols with a degree of hydrolysis in the range of 98 to 99 mol% and a 4% strength aqueous solution viscosity of 3 to 6 mPas. Such PVOH is commercially available or can be obtained by methods known to those skilled in the art. A single PVOH having the degree of hydrolysis may be used, or a combination of two or more PVOHs having different degrees of hydrolysis may be used, which in combination have the degree of hydrolysis.

The protective colloid or combination of protective colloids, e.g., one or more polyvinyl alcohols, will typically be present in an amount of at least 0.1 wt.%, or at least 0.2 wt.%, or 0.5 wt.%. Typically, the amount will be at most 10%, alternatively at most 5% or 1%. These percentages represent the amount of protective colloid relative to the total weight of all monomers used for the polymerization.

Emulsion polymerization process

During the polymerization, the dispersion is stabilized with one or more nonionic surfactants and one or more protective colloids, such as polyvinyl alcohol. VAE dispersions stabilized with a combination of nonionic surfactant and protective colloid can be prepared by emulsion polymerization, typically at temperatures of 40 ℃ to 100 ℃, more typically at temperatures of 50 ℃ to 90 ℃, and most typically at temperatures of 60 ℃ to 80 ℃. The polymerization pressure is generally comprised between 40 and 100 bar, more generally between 45 and 90 bar, and may vary in particular between 45 and 85 bar, depending on the ethylene feed.

Redox initiators may be used in combination with, for example, the initiation of polymerization conventionally used in emulsion polymerization. Redox initiator systems may be used to prepare VAE dispersions suitable for use in the present invention. The initiator may be a formaldehyde generating redox initiation system, such as sodium formaldehyde sulfoxylate. However, in some embodiments, it is desirable to minimize the amount of formaldehyde in the dispersion. In such cases, it is desirable to use a redox initiation system that does not generate formaldehyde. In general, suitable non-formaldehyde-generating reducing agents for use in the redox couple include, as non-limiting examples, those based on ascorbic, bisulfite, erythorbate, or tartaric acids as known in the art, and those manufactured by Bruggerman Chemical of Heilbronn, GermanyFF 6M. Non-redox initiators may also be used, such as peroxides and azo initiatorsHair agents, which are all well known in the art.

All of the monomers may form the initial charge, or all of the monomers may form the feed, or a portion of the monomers may form the initial charge, and the remainder may form the feed after initiation of polymerization. The feeds may be separate (spatially and temporally) or all or some of the components may be fed after pre-emulsification. Once the polymerization process is complete, post-polymerization to remove residual monomer can be carried out using known methods, one example of a suitable method being post-polymerization initiated by a redox catalyst. Volatile residual monomers can also be removed by distillation, preferably at subatmospheric pressure, and where appropriate by passing an inert entraining gas, such as air, nitrogen or water vapor, through or over the material.

Suitable VAE copolymer dispersions are prepared having a solids content of typically 45 to 75% by weight, although dispersions having other solids contents may also be used.

If diluted to 25% solids content, the dispersions typically have a viscosity of at least 5mPas or at least 10, 20 or 30 mPas. The viscosity will typically be at most 80mPas, or at most 70, 60 or 50 mPas. The viscosity was measured using a Brookfield viscometer model LVD with spindle #3 at 60rpm and 25 ℃.

Fibrous nonwoven substrate

The fibrous nonwoven substrate may be natural fibers such as, but not limited to, cellulosic fibers or wood pulp, or synthetic fibers including, but not limited to, the following: one or more of polyester, polyethylene, polypropylene and polyvinyl alcohol, or viscose, or any combination of these, are treated by a dry (air-laid, carded, Rando) or wet-laid process. The basis weight of the fibrous nonwoven substrate is typically at least 10g/m prior to treatment with the nonionic binder composition²Or at least 45g/m²And is usually at most 150g/m²Or at most 120g/m²。

Aqueous disinfectant lotion

The aqueous lotion absorbed in the bonded nonwoven substrate includes one or more cationic disinfecting agents. These are typically quaternary ammonium disinfectant compounds. Benzalkonium chloride is a specific example, although any other cationic disinfecting agent known in the art may be used instead or in addition. Some of the cationic disinfectant may dissolve in the aqueous phase of the lotion, while some adsorbs on the fiber surfaces of the nonwoven substrate. Preferably, the one or more cationic disinfecting agents comprise only one cationic moiety per molecule.

the aqueous lotion can also optionally contain a salt that is not a cationic disinfectant. Any kind of salt may be included, for example, organic salts, inorganic salts, and salts comprising: organic anions and metals, non-disinfecting quaternary ammonium cations or non-quaternary ammonium cations, i.e. NH₄ ⁺Or protonated primary, secondary, or tertiary amines. Non-limiting examples include acetate, acetylide, ammonium salt (excluding quaternary ammonium salts), arsenate, astatate, azide, double halide salt, bicarbonate, double sulfide, boride, borohydride, boron halide, carbonate, citrate, cyanate, cyanide, formate, germanate, glycinate, hypohalite (halates), halide, hydride, hydrogen selenide, hydrogen sulfide, hydroxide, imide, metaniobate, metatantalate, metavanadate, nitrate, nitride, nitrite, oxide, perchlorate, phosphate, phosphine, selenide, selenite, selenate, sulfide, sulfate, ternary salt, non-sterile tetraalkylammonium salt, telluride, thiocyanate, and/or vanadate. Specific examples include potassium citrate, sodium tartrate, potassium lactate, sodium and/or potassium salicylates, magnesium sulfate, sodium chloride, ammonium chloride, and/or potassium chloride. However, any one or more of the above salts, or all salts except the cationic disinfectant, may not be included.

The aqueous lotion can also comprise an organic solvent, which if present, will typically comprise up to 10%, or up to 5%, 2%, or 1% of the lotion composition. Examples include C_1-6Alkanol, C_1-6Diol, C of alkylene glycol_1-10Alkyl ethers, C_3-24Alkylene glycol ethers and/or polyalkylene glycols. Specific classSolvents of type (la) include: alkanols, such as methanol, ethanol, n-propanol, isopropanol, butanol, pentanol and/or hexanol, and the various positional isomers thereof; acetone; and glycol ethers, such as ethylene glycol monopropyl ether, ethylene glycol monobutyl ether, ethylene glycol monohexyl ether, propylene glycol n-propyl ether, propylene glycol monobutyl ether, propylene glycol tert-butyl ether, diethylene glycol monoethyl or monopropyl or monobutyl ether, di-or tripropylene glycol methyl or ethyl or propyl or butyl ether, the acetates and/or propionates of glycol ethers. However, any one or more of the above solvents, or all of the solvents, may not be included.

Making antimicrobial nonwoven wet wipes

The nonionic VAE binder composition is typically applied to the nonwoven substrate by spray application, impregnation, gravure printing, or foaming. The binder composition may optionally comprise a catalyst such as an acidic compound or an ammonium salt thereof. One example is ammonium chloride.

Wetting additives may be included in the binder composition to help wet not only the formulated binder on the substrate, but also the subsequent finished fibrous nonwoven substrate. The wetting additive should be a nonionic or cationic wetting surfactant so as not to reduce the efficacy of the cationic disinfectant added as a lotion to the bonded nonwoven substrate. An example is465, nonionic ethoxylated acetylenic diols sold by Air Products. The wetting agent may be included in the binder composition in an amount of 0.1 to 3 dry parts, based on the weight of the dry polymer, and is more typically formulated in 0.5 to 2 parts.

The compositions are typically applied at a solids content of 0.5% to 30%, depending on the loading desired on the substrate. Typically, the amount of binder will be at least 5%, or at least 10% or 15% by dry weight based on the weight of the untreated substrate. Typically at most 50%, or at most 40% or 30%.

After the binder composition is applied to the substrate, the substrate is dried. This is typically done at a temperature of 120 ℃ to 160 ℃, although higher or lower temperatures may be used. Thereafter, an aqueous lotion comprising a cationic antiseptic may be applied.

Alternatively, the cationic antiseptic may be included in the VAE binder composition, rather than being added separately to the lotion as described above. In that case, water and any other lotion components, such as solvents, may be added to the substrate after the binder composition has been applied and dried, and it is to be understood that some or all of the cationic disinfectant may be dissolved in the water. Alternatively, both ways of adding the cationic disinfectant may be used. In any of these ways, the aqueous lotion will generally be present in an amount of at least 50 parts lotion (wet basis) or at least 150, 200, or 250 parts per 100 parts of bound substrate (dry basis). The amount of lotion is typically up to 500 parts, or up to 400 or 350 parts per 100 parts of substrate. In all cases, the resulting wet wipes may be packaged in any manner effective to reduce or avoid drying out.