阅读说明：本技术 一种含有噁虫酮和拟除虫菊酯的卫生杀虫组合物 (Sanitary insecticidal composition containing oxadixic ketone and pyrethroid ) 是由 章超 贾炜 蒋淦 王宝林 于 2019-10-29 设计创作，主要内容包括：本发明公开了一种含有噁虫酮和拟除虫菊酯的卫生杀虫组合物,有效成分为噁虫酮和拟除虫菊酯,其中：噁虫酮为1％～50％,拟除虫菊酯为1％～10％,余量为助剂；所述的卫生杀虫组合物的剂型为乳油、可溶性液剂、可湿性粉剂。本发明的卫生杀虫组合物,具有高效、低毒、对环境友好等优点,该复配杀虫剂用作空间喷洒和滞留喷洒,见效快,杀灭彻底,延长了施药周期,降低了人工成本。广泛应用于宾馆、学校、工厂、家庭及公共场所,对防治卫生害虫有特效。(The invention discloses a sanitary insecticidal composition containing oxadixic ketone and pyrethroid, which comprises the following effective components: 1 to 50 percent of oxadixic ketone, 1 to 10 percent of pyrethroid and the balance of auxiliary agent; the formulation of the sanitary insecticidal composition is missible oil, soluble liquid and wettable powder. The sanitary insecticidal composition has the advantages of high efficiency, low toxicity, environmental friendliness and the like, and the compound insecticide is used for spatial spraying and delay spraying, is quick in effect taking, can kill thoroughly, prolongs the pesticide application period and reduces the labor cost. The insecticidal composition is widely applied to hotels, schools, factories, families and public places, and has special effects on preventing and controlling sanitary pests.)

1. A hygienic insecticidal composition comprising oxadixic ketone and a pyrethroid, characterized in that: the active ingredients are oxadixicone and pyrethroid, wherein: 1 to 50 percent of oxadixic ketone, 1 to 10 percent of pyrethroid and the balance of auxiliary agent; the formulation of the sanitary insecticidal composition is missible oil, soluble liquid and wettable powder.

2. A sanitary insecticidal composition according to claim 1, characterized in that: the total content of the oxadixic ketone and the pyrethroid is 1 to 60 percent.

3. A sanitary insecticidal composition according to claim 1, characterized in that: the weight ratio of the oxadixic ketone to the pyrethroid is 10: 1-1: 1.

4. A sanitary insecticidal composition according to claim 1, characterized in that: when the formulation of the sanitary insecticidal composition is missible oil, the auxiliary agent is an emulsifier, a slow release agent and a solvent are sprayed in space, and the content of each component is as follows: 1 to 50 percent of oxadixicone, 1 to 10 percent of pyrethroid, 1 to 15 percent of emulsifier, 1 to 30 percent of space spraying sustained release agent and solvent which is complemented to 100 percent.

5. A sanitary insecticidal composition according to claim 1, characterized in that: when the formulation of the sanitary insecticidal composition is soluble liquid, the auxiliary agent is emulsifier, slow release agent and solvent are sprayed in space, and the content of each component is as follows: 1 to 50 percent of oxadixic ketone, 1 to 10 percent of pyrethroid, 5 to 30 percent of emulsifier, 1 to 30 percent of space spraying sustained release agent and solvent which is complemented to 100 percent.

6. A sanitary insecticidal composition according to claim 1, characterized in that: when the formulation of the sanitary insecticidal composition is wettable powder, the auxiliary agents comprise a wetting agent, a dispersing agent, a slow release agent, a rain-resistant scouring agent and a filler, and the content of each component is as follows: 1-50% of oxadixicone, 1-10% of pyrethroid, 1-4% of wetting agent, 1-10% of dispersing agent, 1-10% of sustained-release agent, 1-5% of rain-resistant scouring agent and the balance of filler to 100%.

7. A sanitary insecticidal composition according to claim 1, characterized in that: the pyrethroid is selected from: the composition is a mixture formed by mixing any one of chlorofluoromethrin, tetrafluoroetofenprox, tetrafluoromethothrin, methofluthrin, right-trans-clopropathrin, transfluthrin, phenothrin, heptafluoromethenthrin, right-heptafluoromethenthrin, biological allethrin, permethrin, right-allethrin and right-trans-enriched allethrin in any proportion.

8. A sanitary insecticidal composition according to claim 4 or 5, characterized in that: the space spraying slow release agent is selected from: any one of 2-methyl dimethyl glutarate, dimethyl succinate, N-dimethyl propionamide and propylene carbonate, and a mixture formed by mixing two or more than two of the above components in any proportion.

9. The invention also provides application of the sanitary insect killing composition in preventing and controlling sanitary insects.

10. The use according to claim 9, wherein the sanitary pests are culex pipiens, culex fatigues, culex tritaeniorhynchus, aedes albopictus, aedes aegypti, anopheles sinensis, aedes infestans, midge, houseflies, city flies, chrysomyia megacephala, lucilia sericata, lucilia cuprina, lucilia glauca, latus suavicularis, metalatus latus, blatella germanica, periplaneta americana, bed bugs, fleas, rhynchophyllus, dursban medicinalis, dursban prairia, Boophilus microplus, dermus coriolus and sarcoptian; when the sanitary insect-killing composition is used for preventing and controlling sanitary insects, the sanitary insect-killing composition is diluted by water and then sprayed to hotels, schools, factories, families and public places, wherein: the missible oil and the soluble liquid are diluted by 30-200 times by water and then sprayed into the space, and the wettable powder is diluted by 100-fold by water and sprayed onto the ground or the wall surface by 300-fold.

Technical Field

The invention relates to a binary sanitary insecticidal composition and application thereof, in particular to a sanitary insecticidal composition containing oxadixicone and pyrethroid, and the effective components of the sanitary insecticidal composition are the oxadixicone and the pyrethroid.

Background

The oxadilone belongs to hygienic oxadiazole insecticides, has stomach toxicity and contact poisoning effects on insects, has double characteristics of inhibiting acetylcholinesterase and acting on nerve axons in an action mechanism, and is mainly used as a hygienic insecticide for preventing and treating houseflies, cockroaches and the like.

The sanitary pyrethroid has the effects of stomach toxicity, contact poisoning and fumigation, is a good knock-down agent and a good lethal agent, is widely applied to the field of sanitary medicines, such as mosquito-repellent incense, aerosol, liquid mosquito-repellent incense and the like, and is gradually developed and applied to sanitary external environments at present. The famoxadone and the sanitary pyrethroid are compounded into missible oil, soluble liquid, wettable powder and the like, so that the prevention and control effect on sanitary pests can be improved, the generation of drug resistance of the sanitary pests is delayed, the defects of few sanitary drug products, old products and the like in the domestic and foreign environments are overcome, and the pesticide composition is a compound drug application technology with better market prospect.

Disclosure of Invention

The invention aims to solve the technical problem of providing a sanitary insecticidal composition containing the oxadixic ketone and the pyrethroid aiming at the defects in the prior art, wherein the effective components of the sanitary insecticidal composition are the oxadixic ketone and the pyrethroid; the sanitary insecticidal composition has the advantages of good insecticidal effect, low medication cost, synergistic effect and difficulty in generating drug resistance.

In order to achieve the above purpose, the following technical scheme is adopted (if no special description is provided, the content in the invention refers to the weight percentage content):

a sanitary insecticidal composition containing oxadixic ketone and pyrethroid comprises the following effective components: 1 to 50 percent of oxadixic ketone, 1 to 10 percent of pyrethroid and the balance of auxiliary agent; the formulation of the sanitary insecticidal composition is missible oil, soluble liquid and wettable powder.

In the technical scheme, the total content of the oxadixic ketone and the pyrethroid is 1-60%, and preferably 1-30%.

In the technical scheme, the weight ratio of the oxadixic ketone to the pyrethroid is 10: 1-1: 1, and preferably 10: 1-3: 1.

In the technical scheme, when the formulation of the sanitary insecticidal composition is missible oil, the auxiliary agent is an emulsifier, a slow release agent and a solvent are sprayed in space, and the content of each component is as follows: 1 to 50 percent of oxadixicone, 1 to 10 percent of pyrethroid, 1 to 15 percent of emulsifier, 1 to 30 percent of space spraying sustained release agent and solvent which is complemented to 100 percent.

In the technical scheme, when the formulation of the sanitary insecticidal composition is soluble liquid, the auxiliary agent is an emulsifier, a slow release agent for spatial spraying and a solvent, and the content of each component is as follows: 1 to 50 percent of oxadixic ketone, 1 to 10 percent of pyrethroid, 5 to 30 percent of emulsifier, 1 to 30 percent of space spraying sustained release agent and solvent which is complemented to 100 percent.

In the technical scheme, when the formulation of the sanitary insecticidal composition is wettable powder, the auxiliary agents comprise a wetting agent, a dispersing agent, a slow release agent, a rain-resistant scouring agent and a filling material, and the content of each component is as follows: 1-50% of oxadixicone, 1-10% of pyrethroid, 1-4% of wetting agent, 1-10% of dispersing agent, 1-10% of sustained-release agent, 1-5% of rain-resistant scouring agent and the balance of filler to 100%.

In the above technical scheme, the pyrethroid is selected from: the composition is a mixture formed by mixing any one of chlorofluoromethrin, tetrafluoroetofenprox, tetrafluoromethothrin, methofluthrin, right-trans-clopropathrin, transfluthrin, phenothrin, heptafluoromethenthrin, right-heptafluoromethenthrin, biological allethrin, permethrin, right-allethrin and right-trans-enriched allethrin in any proportion.

In the above technical scheme, the solvent is selected from: trimethylbenzene, tetramethylbenzene, pentamethylene, ethanol, N-dimethyl pelargonamide, N-octyl pyrrolidone, propanol, butanol, ethylene glycol, diethylene glycol, ethylene glycol methyl ether, piperonyl butyl ether, dodecylbenzene, butyl ether, ethyl acetate, dimethyl phthalate, dimethyl diethyl phthalate and dimethyl dibutyl phthalate, wherein two or more of the above components are mixed in any proportion to form a mixture.

In the above technical scheme, the space spraying slow release agent is selected from: any one of 2-methyl dimethyl glutarate, dimethyl succinate, N-dimethyl propionamide and propylene carbonate, and a mixture formed by mixing two or more than two of the above components in any proportion.

In the above technical scheme, the emulsifier is selected from: styrylphenol polyoxyethylene ether, calcium alkylbenzene sulfonate (such as Nongsuan 500# from Nanjing Tekkaido Co., Ltd.), OP series phosphate ester (nonylphenol polyoxyethylene ether phosphate ester), phenylphenol polyoxyethylene ether phosphate ester (such as Nongjindo Tekkaido 600# phosphate ester), styrene polyoxyethylene ether ammonium sulfate salt, magnesium salt of alkyldiphenyl ether disulfonate, triethanolamine salt, benzyldimethylphenol polyoxyethylene ether (such as Nongsuan 400# from Chengtai Lanzhong Co., Ltd.), Ningru 36# (phenethylphenol formaldehyde resin polyoxyethylene ether), phenethylphenol polyoxyethylene polyoxypropylene ether (such as Nongru 1600# from Handan Nedia chemical Co., Ltd.), ethylene oxide-propylene oxide block copolymer, alkylphenol polyoxyethylene ether, castor oil polyoxyethylene ether (such as Tianjin Hongmei EL series), alkylaryl polyoxypropylene polyoxyethylene ether (such as Nanjing Tekkaido 33#), and alkyl diphenyl ether, The material is a mixture of any one of alkylaryl polyoxyethylene polyoxypropylene ether (such as 34# of Sunjin Taihua agricultural emulsion), span series (sorbitan monostearate), Tween series (polyoxyethylene sorbitan fatty acid ester), and fatty alcohol polyoxyethylene ether (such as AEO series of the Schchen Tailan auxiliary agent factory).

In the above technical solution, the wetting agent is selected from: the formaldehyde condensate sulfate of alkylphenol polyoxyethylene ether, alkyl sulfate, alkyl sulfonate, naphthalene sulfonate, sodium dodecyl sulfate, nekal BX and sodium dodecyl benzene sulfonate, and a mixture of two or more than two of them in any proportion.

In the above technical scheme, the dispersant is selected from: any one of polycarboxylate, lignosulfonate, alkylphenol polyoxyethylene formaldehyde condensate sulfate, alkyl benzene sulfonate calcium salt and naphthalene sulfonic formaldehyde condensate sodium salt, and a mixture formed by mixing two or more of the polycarboxylate, the lignosulfonate, the alkylphenol polyoxyethylene formaldehyde condensate sulfate, the alkyl benzene sulfonate calcium salt and the naphthalene sulfonic formaldehyde condensate sodium salt in any proportion.

In the above technical scheme, the sustained release agent is selected from: any one of hydroxymethyl cellulose, modified starch, Arabic gum and polyvinyl alcohol, or a mixture of two or more of the hydroxymethyl cellulose, the modified starch, the Arabic gum and the polyvinyl alcohol in any proportion.

In the technical scheme, the rain wash resistant agent is a trisiloxane surfactant, and is preferably alkoxy modified polytrisiloxane.

In the above technical solution, the filler is selected from: the material is a mixture formed by mixing any one of kaolin, argil, diatomite, bentonite, white carbon black, attapulgite, starch and light calcium carbonate in any proportion.

In the technical scheme, when the formulation of the sanitary insecticidal composition is missible oil, soluble liquid and wettable powder, the sanitary insecticidal composition can be prepared according to the conventional method or the existing method in the field.

The invention also provides application of the sanitary insecticidal composition in the aspect of preventing and controlling sanitary pests.

In the above technical scheme, the sanitary insect pests refer to culex pipiens pallens, culex fatigues, culex tritaeniorhynchus, aedes albopictus, aedes aegypti, anopheles sinensis, aedes infestans, midge, houseflies, city flies, chrysomyia megacephala, lucilia sericata, lucilia glauca, latrine flies, metazoa flies, cockroaches germanica, periplaneta americana, bed bugs, fleas, mangrove ticks, dursban ticks, prairie ticks, Boophilus microplus, Dermatophagoides, and scabies.

In the technical scheme, the hygienic insecticidal composition is diluted by water and sprayed to the application fields of hotels, schools, factories, families, public places and the like when preventing and treating hygienic pests, wherein: the missible oil and the soluble liquid are diluted by 30-200 times by water and then sprayed into the space, and the wettable powder is diluted by 100-fold by water and sprayed onto the ground or the wall surface by 300-fold.

The sanitary insecticidal composition provided by the invention is added with a space spraying slow-release agent aiming at missible oil and soluble liquid, so that the spraying effect is improved, the size of liquid drops in space spraying is reduced, the liquid drops can be extended to stay in the space for a longer time, the drug effect is improved, sanitary pests are killed more thoroughly, the pesticide application period is prolonged, the pesticide application frequency is reduced, and the labor cost is reduced. The compound insecticide is used for space spraying and delay spraying, has quick response and thorough killing, is widely applied to hotels, schools, factories, families and public places, and has special effect on preventing and treating sanitary pests.

Detailed Description

The following detailed description of the embodiments of the present invention is provided, but the present invention is not limited to the following descriptions:

the preparation method of the dosage form in each embodiment of the invention is as follows:

the laboratory preparation method of the missible oil comprises the following steps: weighing the oxadixyl, the pyrethroid and the emulsifier according to the proportion, spacially spraying the slow release agent and the solvent, heating and uniformly mixing in a beaker to obtain the pesticide.

The laboratory preparation method of the soluble liquid comprises the following steps: weighing the oxadixyl, the pyrethroid and the emulsifier according to the proportion, spacially spraying the slow release agent and the solvent, and heating and fully dissolving to obtain the soluble liquid.

The laboratory preparation method of the wettable powder comprises the following steps: adding the oxadixyl, the pyrethroid, the wetting agent, the dispersing agent, the slow release agent, the rain-resistant scouring agent and the filler into a food processor, uniformly mixing, and then feeding into a jet mill for crushing to obtain the product.

The invention will now be illustrated with reference to specific examples:

formulation example 1: 3.5% averone-chloro-fluoro-ethofenprox missible oil

3% of averone, 0.5% of meperfluthrin, 3% of calcium alkyl benzene sulfonate, 4% of castor oil polyoxyethylene ether, 2% of phenyl phenol polyoxyethylene ether phosphate, 10% of propylene carbonate and the balance of dodecyl benzene to 100%.

Formulation example 2: 10% soluble liquid of avermectin-meperfluthrin

9% of averone, 1% of meperfluthrin, 5% of calcium alkyl benzene sulfonate, 12% of castor oil polyoxyethylene ether, 10% of N, N-dimethyl propionamide, 2% of piperonyl butoxide, 20% of trimethylbenzene and the balance of dodecylbenzene to 100%.

Formulation example 3: 30% oxacloprid-meperfluthrin wettable powder

25% of averone, 5% of Meperfluthrin, 4% of sodium dodecyl benzene sulfonate, 6% of lignosulfonate, 5% of modified starch, 2% of alkoxy modified polytriesiloxane, 15% of white carbon black and 100% of kaolin.

Formulation example 4: 3.5% averone-tetrafluoethrin emulsifiable concentrate

3% of bakanae ketone, 0.5% of tefluthrin, 3% of calcium alkyl benzene sulfonate, 4% of castor oil polyoxyethylene ether, 2% of phenyl phenol polyoxyethylene ether phosphate, 15% of 2-methyl dimethyl glutarate and the balance of dodecyl benzene to 100%.

Formulation example 5: 4% soluble liquid agent of oxacloprid and tefluthrin

3% of averone, 1% of tefluthrin, 5% of calcium alkyl benzene sulfonate, 12% of castor oil polyoxyethylene ether, 10% of N, N-dimethyl propionamide, 2% of piperonyl butoxide, 15% of tetramethylbenzene and dodecyl benzene to make up to 100%.

Formulation example 6: 15% oxacloprid-tefluthrin wettable powder

12% of averone, 3% of tefluthrin, 4% of sodium dodecyl benzene sulfonate, 6% of lignosulfonate, 2% of sodium naphthalene sulfonate formaldehyde condensate, 5% of polyvinyl alcohol, 2% of alkoxy modified polytrisiloxane, 10% of white carbon black and 100% of diatomite.

Formulation example 7: 4% averone-tetrafluoromethrin emulsifiable concentrate

3% of oxacloprid, 1% of dimefluthrin, 3% of calcium alkylbenzene sulfonate, 36# 6% of Ningru, 1% of phenyl phenol polyoxyethylene ether phosphate, 10% of 2-methyl dimethyl glutarate and the balance of dodecyl benzene to 100%.

Formulation example 8: 6% soluble liquid agent of hymexazol and tetrafluoromethrin

5% of averone, 1% of tetrafluoromethothrin, 4% of calcium alkyl benzene sulfonate, 15% of castor oil polyoxyethylene ether, 13% of N, N-dimethyl propionamide, 2% of piperonyl butoxide and tetramethylbenzene, wherein the balance is up to 100%.

Formulation example 9: 10% wettable powder of oxacloprid-tetramethrin

9% of averone, 1% of tetramethrin, 4% of sodium dodecyl benzene sulfonate, 6% of lignosulfonate, 3% of modified starch, 2% of alkoxy modified polytrisiloxane, 10% of white carbon black and the balance of diatomite to 100%.

Formulation example 10: 3.5% of avermectin-methoxybenzyl-fluthrin missible oil

3% of averone, 0.5% of bifenthrin, 2% of calcium alkyl benzene sulfonate, 36# of Ningru, 5%, 1% of phenyl phenol polyoxyethylene ether phosphate, 15% of 2-dimethyl glutarate and the balance of dodecyl benzene to 100%.

Formulation example 11: 8% soluble liquid agent of avermectin-methoxybenzofloxacin

6% of averone, 2% of metofluthrin, 5% of calcium alkyl benzene sulfonate, 16% of castor oil polyoxyethylene ether, 11% of N, N-dimethyl propionamide, 2.5% of piperonyl butoxide and dodecyl benzene to make up to 100%.

Formulation example 12: 20% wettable powder of hymexazol-methoxybenzathithrin

18% of averone, 2% of methoxybenzofloxacin, 2% of alkyl sulfonate, 5% of polycarboxylate, 1% of lignosulfonate, 4% of hydroxymethyl cellulose, 2.5% of alkoxy modified polytrisiloxane, 6% of white carbon black and 100% of kaolin.

Formulation example 13: 3.5% averone-D-trans-chlorpropyrifos missible oil

3% of averone, 0.5% of d-trans-chloropropynthrin, 3% of calcium alkyl benzene sulfonate, 36# 6% of Ningru, 1% of phenyl phenol polyoxyethylene ether phosphate, 10% of 2-methyl dimethyl glutarate, 5% of ethanol and the balance of trimethylbenzene to 100%.

Formulation example 14: 3.5% averone-D-trans-chlorpropyrifos missible oil

3% of averone, 0.5% of d-trans-chlorpropyrifos, 3% of calcium alkyl benzene sulfonate, 36# of Ningru, 1% of phenyl phenol polyoxyethylene ether phosphate, 5% of ethanol and trimethyl benzene, and the balance is up to 100%.

Formulation example 15: 27% avermectin-dextro-trans-chloropropyne wettable powder

24% of averone, 3% of dextro-trans-chloropropyne, 3% of alkyl sulfonate, 6% of polycarboxylate, 4% of polyvinyl alcohol, 2% of alkoxy modified polytrisiloxane and 100% of kaolin.

Formulation example 16: 3.5% of avermectin-transfluthrin emulsifiable concentrate

3% of bakelite, 0.5% of transfluthrin, 3% of calcium alkyl benzene sulfonate, 36# 6% of Ningru, 1% of phenyl phenol polyoxyethylene ether phosphate, 10% of propylene carbonate and the balance of dodecyl benzene to 100%.

Formulation example 17: 8% soluble liquid of hymexazol and transfluthrin

7% of averone, 1% of transfluthrin, 3% of calcium alkyl benzene sulfonate, 16% of styryl phenol polyoxyethylene ether, 15% of propylene carbonate, 6% of piperonyl butoxide, 8% of ethanol and the balance of tetramethylbenzene to 100%.

Formulation example 18: 10% wettable powder of oxacloprid and transfluthrin

9% of averone, 1% of transfluthrin, 2% of alkyl sulfonate, 5% of polycarboxylate, 3% of naphthalenesulfonic acid formaldehyde condensate sodium salt, 4% of modified starch, 2% of alkoxy modified polytrisiloxane, 8% of white carbon black and 100% of kaolin.

Formulation example 19: 4% aversion ketone-phenothrin emulsifiable concentrate

3.5 percent of the avermectin, 0.5 percent of the phenothrin, 2 percent of the calcium alkyl benzene sulfonate, 4 percent of benzyl dimethyl phenol polyoxyethylene ether, 2 percent of phenyl phenol polyoxyethylene ether phosphate, 10 percent of dimethyl succinate and dodecyl benzene which are complemented to 100 percent.

Formulation example 20: 5% soluble liquid agent of oxacloprid and phenothrin

4.5 percent of the averone, 0.5 percent of the phenothrin, 3 percent of the calcium alkyl benzene sulfonate, 15 percent of styryl phenol polyoxyethylene ether, 12 percent of the N, N-dimethyl propionamide, 4 percent of the piperonyl butoxide, 5 percent of the ethanol and the trimethyl benzene are complemented to 100 percent.

Formulation example 21: 12% oxacloprid-phenothrin wettable powder

10% of the averone, 2% of the phenothrin, 2% of the alkyl sulfonate, 5% of the polycarboxylate, 4% of the hydroxymethyl cellulose, 3% of the alkoxy modified polytrisiloxane, 8% of the white carbon black and the balance of the pottery clay to 100%.

Formulation example 22: 4% averone-heptafluoromethyl ether pyrethrin emulsifiable concentrate

3.5 percent of the avermectin, 0.5 percent of the metaflumethrin, 2 percent of the calcium alkyl benzene sulfonate, 4 percent of benzyl dimethyl phenol polyoxyethylene ether, 3 percent of phenyl phenol polyoxyethylene ether phosphate, 8 percent of dimethyl succinate and dodecyl benzene which are complemented to 100 percent.

Formulation example 23: 8% soluble liquid agent of hymexazol-d-heptafluoro methothrin

6% of averone, 2% of d-heptafluoromethyl ether, 6% of calcium alkyl benzene sulfonate, 15% of styrylphenol polyoxyethylene ether, 12% of N, N-dimethyl propionamide, 4% of piperonyl butoxide, 5% of ethanol and the balance of trimethylbenzene to 100%.

Formulation example 24: 11% hymexazol-d-heptafluoro methothrin wettable powder

10% of avermectin, 1% of d-heptafluoro methyl ethofenprox, 3% of alkyl sulfonate, 6% of polycarboxylate, 3% of hydroxymethyl cellulose, 1.5% of alkoxy modified polytrisiloxane, 7% of white carbon black and 100% of attapulgite.

Formulation example 25: 4% averone-chlorenthrin emulsifiable concentrate

3.5 percent of the avermectin, 0.5 percent of the prallethrin, 2 percent of the calcium alkyl benzene sulfonate, 4 percent of benzyl dimethyl phenol polyoxyethylene ether, 3 percent of phenyl phenol polyoxyethylene ether phosphate, 15 percent of dimethyl succinate and dodecyl benzene which are complemented to 100 percent.

Formulation example 26: 10% soluble liquid agent of oxacloprid-permethrin

9% of averone, 1% of prallethrin, 5% of calcium alkyl benzene sulfonate, 12% of castor oil polyoxyethylene ether, 8% of N, N-dimethyl propionamide, 3% of piperonyl butoxide, 12% of trimethylbenzene and the balance of dodecylbenzene to 100%.

Formulation example 27: 20% oxacloprid-permethrin wettable powder

The pesticide composition comprises 15% of the averone, 5% of the prallethrin, 4% of alkyl sulfonate, 6% of polycarboxylate, 2% of hydroxymethyl cellulose, 2% of alkoxy modified polytrisiloxane and kaolin which is supplemented to 100%.

Formulation example 28: 4% aversion ketone-biological allethrin emulsifiable concentrate

3.5 percent of the avermectin, 0.5 percent of the biological allethrin, 3 percent of the calcium alkyl benzene sulfonate, 4 percent of benzyl dimethyl phenol polyoxyethylene ether, 1 percent of phenyl phenol polyoxyethylene ether phosphate, 10 percent of dimethyl succinate and dodecyl benzene which are complemented to 100 percent.

Formulation example 29: 8% soluble agent of bakanae ketone and biological allethrin

6% of averone, 2% of biological allethrin, 8% of calcium alkyl benzene sulfonate, 12% of styryl phenol polyoxyethylene ether, 15% of N, N-dimethyl propionamide, 3% of piperonyl butoxide, 3% of ethanol and the balance of dodecyl benzene to 100%.

Formulation example 30: wettable powder of 7% averone and biological allethrin

6% of averone, 1% of biological allethrin, 2% of alkyl sulfonate, 5% of polycarboxylate, 2% of lignosulfonate, 2% of polyvinyl alcohol, 1% of alkoxy modified polytrisiloxane, 8% of white carbon black and 100% of kaolin.

The first application embodiment: pesticide effect test for preventing and controlling indoor space spraying of mosquitoes and flies

Test targets: culex pipiens pallens, female adults who do not take blood 3 to 5 days after eclosion;

housefly, adult, female and male half of 3 to 4 days after eclosion;

the test method comprises the following steps: referring to GB/T13917.10-2009, a field-cage hanging method is simulated;

and (3) test treatment: the total concentration of the effective components of the preparation examples 1, 2, 4, 5, 7 and 8 is diluted to 200 mg/L;

control 1: diluting 5% oxadixyl emulsifiable concentrate to 200 mg/L;

control 2: diluting 5% of meperfluthrin emulsifiable concentrate to 200 mg/L;

control 3: diluting 5% of tefluthrin emulsifiable concentrate to 200 mg/L;

control 4: diluting 5% of tetramethrin emulsifiable concentrate to 200mg/L

And (3) test results:

table 1 part of formulation examples space spray efficacy test against mosquitoes and flies

Test results show that after the insecticidal ketone is compounded with the cyhalothrin, the tetrafluoro ether and the tetrafluoro methothrin, the synergistic effect on the knockdown effect of mosquitoes and flies is obvious, the fatality rate in 24 hours is also obviously improved and reaches 100 percent (shown in table 1), the cyhalothrin, the tetrafluoro ether and the tetrafluoro methothrin make up for the defect of weaker knockdown performance of the insecticidal ketone, and the insecticidal ketone makes up for the defect of poorer fatality of the cyhalothrin, the tetrafluoro ether and the tetrafluoro methothrin.

TABLE 2 determination of co-toxicity coefficient of averone and Meperfluthrin (for culex pipiens pallens)

As shown in Table 2, when the compounding ratio of the avermectin to the meperfluthrin is 10: 1-1: 1, the cotoxicity coefficient of the culex pipiens pallens is more than 120, and the synergistic effect is obvious, particularly when the compounding ratio is 6: 1.

TABLE 3 optimal cotoxicity coefficient of averone with other pyrethroids (against Culex pallida)

As shown in the table 3, the optimal proportion of the compound of the avermectin and other pyrethroid is within the range of 8: 1-3: 1, and particularly, the co-toxicity coefficients of the tetrafluoro ethofenprox, the tetrafluoro methothrin, the metofluthrin, the d-trans-chlorpropenthrin, the heptafluoro methothrin and the d-heptafluoro methothrin are all more than 200, so that the synergistic effect is obvious.

Application example two: space spraying slow release agent effect and drug effect test

Test targets: culex pipiens pallens, female adults who do not take blood 3 to 5 days after eclosion;

the test method comprises the following steps: referring to GB/T13917.10-2009, a field-cage hanging method is simulated;

and (3) test treatment: preparation examples 13 and 14, the total concentration of the active ingredients is diluted to 200 mg/l;

spraying equipment: longrui 616A for a small backpack sprayer;

table 4 formulation examples 13 and 14 efficacy comparison data

Formulation example 13 and formulation example 14 are both 3% avermectin + 0.5% d-trans-propargyl chloride pyrethrin emulsifiable concentrate, wherein formulation example 13 is added with 2-methyl glutaric acid dimethyl ester, formulation example 14 is not added, as can be seen from table 2, formulation example 13 has significantly better efficacy than formulation example 14, the diameter of the fog drop sprayed by formulation example 13 is about 35 μm, and the diameter of the fog drop of formulation example 14 is about 62 μm, because the larger the diameter of the fog drop, the smaller the number of dispersible granules of the liquid medicine in the air, and the fast sedimentation rate of the liquid medicine granules, the short suspension time in the air, which results in poor efficacy.

Application example three: pesticide effect test for indoor retention and spraying of mosquitoes and flies

Test targets: culex pipiens pallens, female adults who do not take blood 3 to 5 days after eclosion;

housefly, adult, female and male half of 3 to 4 days after eclosion;

the test method comprises the following steps: reference is made to GB/T13917.1-2009, the forced contact method;

and (3) test treatment: the total concentration of the active ingredients of the preparation examples 3, 6 and 9 is diluted to 400 mg/l;

control 5: diluting 5% of the avermectin wettable powder to 400 mg/L;

control 6: diluting 5% of meperfluthrin wettable powder to 400 mg/L;

control 7: diluting 5% of tefluthrin wettable powder to 400 mg/L;

control 8: 5% tetrafluoromethothrin wettable powder is diluted to 400mg/L

And (3) test results:

table 5 part of formulation examples retention spray efficacy test against mosquitoes and flies

Test results show that the preparation examples 3, 6 and 9 have obvious synergistic effect on the knockdown effect of mosquitoes and flies, and the fatality rate of 24h is higher than that of a control sample and reaches more than 95% (see table 5)

In order to ensure the persistence of the spraying medicament, the sustained-release agent is added in the preparation example to ensure the persistence of the spraying, the persistence tests are carried out aiming at the preparation examples 3, 6 and 9, and the concentration of the effective component is 400 mg/l;

controls 9, 10, 11 are formulations of formulation examples 3, 6, 9, respectively, without the addition of a sustained release agent;

specific results are shown in table 6:

table 6 part of the formulation examples for slow release and duration test of mosquito and fly

As shown in table 6, the formulations of examples 3, 6 and 9 still have good knockdown effect against mosquitoes and flies after being stored in the air for 15 days and 30 days, the drug effect is slowly reduced, and the effective period is longer, while the control samples 9, 10 and 11 (without adding the sustained release agent in the formulation) have fast drug effect reduction after 15 days and 30 days, and the knockdown rate is obviously reduced after 30 days.

Meanwhile, a rain erosion resistance test is carried out on preparation examples 3, 6 and 9, water is sprayed to the board surface with the medicament by using an artificial water spraying method, the process of rainfall erosion of the board surface is simulated, and forced contact pesticide effect measurement is carried out after the board surface is naturally dried.

Setting controls 12, 13, 14: the formulations of the preparations of examples 3, 6 and 9 are respectively simulated, and no rain-resistant scouring agent is added.

The results of the specific drug efficacy measurements are shown in table 7:

table 7 efficacy test of rainwash resistance of some formulation examples

As shown in table 7, the pharmaceutical effects of formulation examples 3, 6 and 9 were reduced after spraying water manually, but the reduction was low in magnitude, and the knockdown rate was still high. The drug effect of the control samples 12, 13 and 14 (imitating the formulations of the preparation examples 3, 6 and 9 and not adding the rain-resistant scouring agent) is obviously reduced after the water is sprayed artificially.

Application example four: pesticide effect test for preventing and controlling cockroach

Test targets: blattella germanica, adults of 10-15 days old and female half and half;

the test method comprises the following steps: reference is made to GB/T13917.1-2009, the forced contact method;

and (3) test treatment: the total concentration of the active ingredients of the preparation examples 3, 6 and 9 is diluted to 400 mg/l;

control 15: diluting 5% of the avermectin wettable powder to 400 mg/l;

control 16: diluting 5% of meperfluthrin wettable powder to 400 mg/l;

control 17: diluting 5% of tefluthrin wettable powder to 400 mg/l;

control 18: diluting 5% of tetramethrin wettable powder to 400 mg/l;

table 8 part of formulation examples are directed to the pharmaceutical efficacy test of german cockroach

As shown in Table 8, the preparation examples 3, 6 and 9 have obvious knock-down effect on the German cockroach at 1h, which is much better than the control sample, the knock-down rate of the preparation examples 3, 6 and 9 on the German cockroach at 6h reaches 100%, and the knock-down rate of the control samples 16, 17 and 18 does not reach 100%.

In conclusion, the sanitary insecticidal composition containing the averone and the pyrethroid has obvious synergistic effect on sanitary pests after the averone and the pyrethroid are compounded, and the compounded insecticide is used for space spraying and delay spraying, has quick response and thorough killing, prolongs the pesticide application period and reduces the labor cost. The insecticidal composition is widely applied to hotels, schools, factories, families and public places, and has special effects on preventing and controlling sanitary pests.

The above examples are only for illustrating the technical concept and features of the present invention, and are not intended to limit the scope of the present invention. All equivalent changes or modifications made according to the spirit of the present invention should be covered within the protection scope of the present invention.