Medicine for treating intervertebral disc disease and cervical vertebra discomfort

文档序号:1724732 发布日期:2019-12-20 浏览:27次 中文

阅读说明:本技术 一种治疗椎间盘症和颈椎不适的药物 (Medicine for treating intervertebral disc disease and cervical vertebra discomfort ) 是由 李若 于 2019-10-09 设计创作,主要内容包括:本发明涉及一种治疗椎间盘症和颈椎不适的药物,由主药、辅药和药基构成,先分别按份数制备主药和药基,再让主药和辅药按比例1:0.005~0.01制备得到原药,然后让原药和药基按比例1:10~2:10制备得到药膏,其中,辅药为川红花,所述主药和药基由以下按重量份计的组分制成:主药包括干燥成粉的猪苦胆2~5份、明矾1~4份;药基包括松香3~6份、大豆油0.5~2份。(The invention relates to a medicament for treating intervertebral disc and cervical vertebra discomfort, which consists of a main medicament, an auxiliary medicament and a medicament base, wherein the main medicament and the medicament base are prepared according to parts respectively, and then the main medicament and the auxiliary medicament are mixed according to the proportion of 1: 0.005-0.01, preparing the original drug, and mixing the original drug and the drug base according to the proportion of 1: 10-2: 10, preparing the ointment, wherein the auxiliary medicine is saffron, and the main medicine and the medicine base are prepared from the following components in parts by weight: the main drugs comprise 2-5 parts of pig gall and 1-4 parts of alum which are dried into powder; the drug base comprises 3-6 parts of rosin and 0.5-2 parts of soybean oil.)

1. A medicament for treating intervertebral disc and cervical vertebra discomfort is characterized by comprising a main medicament, an auxiliary medicament and a medicament base, wherein the main medicament and the medicament base are prepared respectively according to parts, and then the main medicament and the auxiliary medicament are mixed according to a ratio of 1: 0.005-0.01, preparing the original drug, and mixing the original drug and the drug base according to the proportion of 1: 10-2: 10, preparing the ointment, wherein the auxiliary medicine is saffron, and the main medicine and the medicine base are prepared from the following components in parts by weight:

the main drugs comprise 2-5 parts of pig gall and 1-4 parts of alum which are dried into powder;

the drug base comprises 3-6 parts of rosin and 0.5-2 parts of soybean oil.

2. The medicine for treating intervertebral disc disorders and cervical spondylosis as claimed in claim 1, wherein the preparation method comprises the following steps:

(1) preparing the main medicine

(1.1) firstly preparing an alum aqueous solution, obtaining alum according to the weight part ratio, putting the alum into a pot, adding purified water, wherein the ratio of the purified water to the alum is 2: 1; then heating the pot, controlling the temperature in the pot to be 80-90 ℃, and then stirring; until alum is completely dissolved;

(1.2) adding dried pig gall, namely pig gall powder, which is obtained by drying into powder according to the weight part ratio, into the prepared alum aqueous solution, and stirring until the mixture is completely uniform;

(1.3) fully stirring the alum aqueous solution added with the pig gall powder for 20-30 minutes;

(1.4) drying the fully stirred solution to obtain the main drug, wherein the drying temperature is controlled to be 45-55 ℃, the drying time is 20 hours, and the drying mode is drying;

(1.5) crushing the dried main drug to 140 meshes;

(2) adjuvant preparation

(2.1) pulverizing the saffron to obtain the adjuvant, wherein the pulverizing fineness is 80 meshes;

(3) preparation of drug base

(3.1) preparing soybean oil and rosin according to the weight part ratio; simultaneously, adding soybean oil and rosin into a pot for decocting, controlling the temperature in the pot to be 200-240 ℃, continuously stirring to ensure that the soybean oil and the rosin are uniform, and decocting and forming the paste;

(3.2) soaking the decocted and formed paste body in normal-temperature purified water for 100 hours to obtain a medicine base, and replacing the purified water every 8 hours in the soaking process;

(4) preparation of technical material

(4.1) mixing the main medicine after being crushed and the auxiliary medicine after being crushed according to the proportion of 1: 0.005-0.01, putting into a pot, stirring, and uniformly mixing to obtain a raw pesticide;

(5) preparation of ointment

(5.1) heating the obtained medicine base in a pot to 60-70 ℃, and then mixing the raw medicine and the medicine base according to the proportion of 1: 10-2: 10 adding the raw medicine into a pot, stirring uniformly, tabletting and forming, and naturally cooling to obtain the finished product of the ointment.

Technical Field

The invention relates to a medicine for treating intervertebral disc diseases and cervical vertebra discomfort.

Background

At present, mobile phones and computers are more and more common, people often lean down to play mobile phones, or due to work needs, many people are in a sitting position and a jolting state for a long time, and intervertebral disc diseases are easily induced. In addition, intervertebral disc diseases are also easily induced by increasing abdominal pressure, abnormal waist posture, sudden weight bearing, pregnancy, cold exposure, dampness exposure and the like.

The cartilaginous junction between the vertebral bodies of two adjacent vertebrae of an intervertebral disc (intervertebral disc) is called the intervertebral disc. Consisting of a peripheral annulus fibrosus and a central nucleus pulposus.

Intervertebral disc diseases can be divided into cervical and lumbar vertebrae according to the affected part. Correspondingly, the affected part is called cervical discomfort in cervical vertebra and intervertebral disc disease in lumbar vertebra.

Cervical vertebra discomfort can cause headache, dizziness, visual deterioration, faint, lower limb tingling, difficulty in swallowing, chest distress, great blood pressure change and other problems, for example, headache and dizziness can occur due to frequent low head, nerve compression, and symptoms of nausea and vomiting can occur in severe cases. The deformation of cervical vertebrae can press nerves, and the cervical vertebrae causes blood supply insufficiency, which may cause damage of central nerves and visual deterioration. If the brain rotates suddenly, the oxygen consumption of the brain is not supplied enough, which may cause a faint. When the cervical vertebrae are pressed for a long time, the lower limbs may be numb, and the feet cannot be stepped on the solid ground when walking, so that the symptoms of paralysis of the lower limbs may appear in the past. The cervical vertebra deforms and presses the esophagus to cause dysphagia, and some people may have symptoms of nausea, chest distress and inappetence. The cervical vertebra deforms and presses the pectoralis major, and chest distress and chest pain may occur. The long-term compression of the vertebral artery causes the blood pressure of people to change greatly, which causes insufficient oxygen supply and sometimes high or low blood pressure.

The lower lumbar vertebra and the legs of the patient with the intervertebral disc disease have continuous dull pain, and the pain is more and more intense.

Clinically, intervertebral disc disease mainly manifests as lumbago, difficulty in bending down and difficulty in standing up of a patient, and cervical vertebra discomfort mainly manifests as cervical vertebra pain of the patient.

The existing treatment for intervertebral disc diseases and cervical vertebra discomfort generally adopts ointment, physical therapy, massage and operation treatment. The existing ointment has unstable curative effect and cannot achieve the aims of quickly relieving discomfort of patients and easing pain. The treatment by physical therapy, massage and massage is not suitable for all patients, and some patients can aggravate the disease. Although the surgical treatment is quick and convenient, the surgical cost and the risk are high, once the surgery fails, the patient cannot perform other recovery treatments, and the possibility of disability exists.

Therefore, it is urgently needed to provide a medicine for treating intervertebral disc diseases and cervical vertebra discomfort, which can quickly relieve discomfort of patients, relieve pain, not aggravate diseases and eliminate risks.

Disclosure of Invention

The invention aims to provide a medicine for treating discopathy and cervical vertebra discomfort, which can quickly relieve the discomfort of a patient, relieve pain, not aggravate the illness state of the patient and effectively eliminate risks.

The invention relates to a medicament for treating intervertebral disc and cervical vertebra discomfort, which consists of a main medicament, an auxiliary medicament and a medicament base, wherein the main medicament and the medicament base are prepared according to parts respectively, and then the main medicament and the auxiliary medicament are mixed according to the proportion of 1: 0.005-0.01, preparing the original drug, and mixing the original drug and the drug base according to the proportion of 1: 10-2: 10, preparing the ointment, wherein the auxiliary medicine is saffron, and the main medicine and the medicine base are prepared from the following components in parts by weight:

the main drugs comprise 2-5 parts of pig gall and 1-4 parts of alum which are dried into powder;

the drug base comprises 3-6 parts of rosin and 0.5-2 parts of soybean oil.

The preparation method of the medicine for treating the intervertebral disc disease and cervical vertebra discomfort comprises the following steps:

(1) preparing the main medicine

(1.1) firstly preparing an alum aqueous solution, obtaining alum according to the weight part ratio, putting the alum into a pot, adding purified water, wherein the ratio of the purified water to the alum is 2: 1; then heating the pot, controlling the temperature in the pot to be 80-90 ℃, and then stirring; until alum is completely dissolved;

(1.2) adding dried pig gall, namely pig gall powder, which is obtained by drying into powder according to the weight part ratio, into the prepared alum aqueous solution, and stirring until the mixture is completely uniform; in the step, the alum water does not need to be kept at 80-90 ℃, namely, the naturally cooled alum water solution completely meets the conditions;

(1.3) fully stirring the alum aqueous solution added with the pig gall powder for 20-30 minutes;

(1.4) drying the fully stirred solution to obtain the main drug, wherein the drying temperature is controlled to be 45-55 ℃, the drying time is 20 hours, and the drying mode is drying;

(1.5) crushing the dried main drug to 140 meshes;

(2) adjuvant preparation

(2.1) pulverizing the saffron to obtain the adjuvant, wherein the pulverizing fineness is 80 meshes;

(3) preparation of drug base

(3.1) preparing soybean oil and rosin according to the weight part ratio; simultaneously, adding soybean oil and rosin into a pot for decocting, controlling the temperature in the pot to be 200-240 ℃, continuously stirring to ensure that the soybean oil and the rosin are uniform, and decocting and forming the paste;

(3.2) soaking the decocted and formed paste body in normal-temperature purified water for 100 hours to obtain a medicine base, and replacing the purified water every 8 hours in the soaking process;

(4) preparation of technical material

(4.1) mixing the main medicine after being crushed and the auxiliary medicine after being crushed according to the proportion of 1: 0.005-0.01, putting into a pot, stirring, and uniformly mixing to obtain a raw pesticide;

(5) preparation of ointment

(5.1) heating the obtained medicine base in a pot to 60-70 ℃, and then mixing the raw medicine and the medicine base according to the proportion of 1: 10-2: 10 adding the raw medicine into a pot, stirring uniformly, tabletting and forming, and naturally cooling to obtain the finished product of the ointment.

The preparation process of the ointment is a process which is specially set for exerting the optimal effect of the medicinal components. For this reason, the steps cannot be confused or reversed; the temperature and time control also needs to be strictly controlled.

The invention relates to an ointment prepared from a medicine for treating intervertebral disc diseases and cervical vertebra discomforts, which comprises the following steps: is applied to the affected part. The ointment is replaced every 2 days, and 7 days is a treatment course. The pain is significantly relieved. There was no pain felt as healing.

The medicinal components in the invention are all commercial products.

1. The pig gall bladder:

[ TOXIC ] can inhibit heart and nerve at high dose, and has direct toxic effect on nerve and muscle.

[ PROPERTIES AND FLAVOUR ] bitter in taste; cold in nature

[ GUIJING ] liver; a bladder; a lung; the large intestine channel

[ FUNCTIONAL INDICATIONS ] clear heat; moistening dryness; and (5) detoxifying. Dryness and thirst in the major febrile diseases; constipation; cough; asthma; conjunctival congestion; nebula; diarrhea and dysentery; jaundice; pharyngitis; purulent otitis media; carbuncle, deep-rooted carbuncle and furuncle; fistula of rats; eczema; tinea capitis

[ dosage for usage ] oral administration: decocting 6-9 g; or extracting juice 3-6g each time; or made into pill or powder. External use: proper amount, and applying, dropping eyes or clysis. [ discussion of the various families ] compendium: the cold property of pig gallbladder is predominant in the recipe, and it is sweet in property and can moisten dryness, bitter in property and can enter heart and remove liver and gallbladder fire.

[ extract ] China materia Medica

2. Alum:

aluminum potassium sulfate dodecahydrate, also known as: alum, potassium alum and potassium alum, which are banned from using in food additive by the country, are double salts of potassium sulfate and aluminum sulfate containing crystal water. The colorless cubic crystal is usually octahedral in appearance, or forms a poly-shape with a cubic or rhombic dodecahedron, sometimes is attached to a container wall by a {111} surface to form a hexagonal plate shape, belongs to an alpha-type alum complex salt, and has glass luster. Density 1.757g/cm3, melting point 92.5 ℃. 9 molecular crystal water is lost at 92.5 ℃, 12 molecular crystal water is lost at 200 ℃, and the crystal water is soluble in water and insoluble in ethanol. Alum is sour, astringent, cold and toxic in taste. So it has antibacterial and astringent effects, and can be used as Chinese medicine.

3. Rosin:

[ PROPERTIES AND FLAVOUR GUIDING CHANNEL ] is bitter, sweet and warm. (I) Ben Jing: bitter taste and warm nature. ' 2 ' Biyu ': sweet and non-toxic. (iii) treatise on herb Property: "sweet and mild". ' materia Medica (materia Medica): bitter and pungent taste, warm. Enter liver and spleen meridians. Firstly, Lei Gong processing property of medicine: enter spleen and lung meridians. ② Des Desluo Ben Cao: "entering the Taiyin channel of hand and Yangming channel of foot". (iii) materia Medica: enter liver and spleen. "

[ FUNCTIONS ] can dispel pathogenic wind, remove dampness, promote granulation, and relieve pain, and is suitable for treating carbuncle, furuncle, pyocutaneous disease, eczema, traumatic hemorrhage, burn and scald.

[ dosage for usage ] 1-3 money, and is administered in pill or wine. Proper dosage is used for external application, and the plaster is added or ground into powder and then is applied to the affected part.

[ synonyms ] rosin, pine cream, pine fat (Ben Jing), pine gum fragrance (Liu Xiao Gui Yi Fang), asphalt (hygienic Bao Jian), white rosin (Dian nan Ben Cao), pine gum (gang mu), yellow fragrance (Ben Cao Yuan originally) and pine gum fragrance (Cao mu Bian Fang).

[ SOURCE ] is oleoresin obtained from trunk of Pinus massoniana belonging to Pinaceae or congeneric plant, and is distilled to remove volatile oil. Plant morphology is seen in "pine knot" bars.

[ MEDICINAL HERBA ] Colophonium is in the form of irregular semitransparent blocks with different sizes. The surface is yellow, and a layer of yellowish white frost powder is usually present. It is firm and brittle at normal temperature, and has bright cross section and similar glass shape. Has turpentine odor and bitter taste. It is softened by heating and then melted, and generates brown smoke when burning. The preferred is neat, translucent, oily, and strong smell.

4. Soybean oil:

soybean oil is sweet and pungent in flavor, hot in nature and slightly toxic;

has effects in expelling intestinal parasites and moistening intestine;

it can be used for treating intestinal obstruction and constipation, and also for treating various sores, scabies, toxic stasis, etc.

5. Safflower carthamus:

carthami flos (Carthamus tinctorius) is a plant of Compositae (Compositae). Also named as safflower, mangrove, etc. Annual or biennial herbs. The leaves are in the shape of needles and have sharp teeth at the edge. The florae in the shape of a tube are all tubular flowers, yellow at the beginning of blooming and gradually become orange red. The lean fruit is white. The flowering period is 6-7 months, and the fruit period is 8-9 months. They are fond of warm and dry climate, and have certain cold resistance, drought resistance, salt tolerance and water logging intolerance. Native egypt, cultivated in europe, america, australia and china, among many other places.

Safflower is a traditional medicinal plant and has a long history of application. It has many effects, is edible, and can be used as feed, fuel, and oil. Safflower has higher medicinal value, can play the roles of activating blood and dredging channels, dissipating blood stasis and relieving pain, and has obvious effect in treating diseases such as traumatic injury, continuous lochia, chest stuffiness and pains, amenorrhea and the like.

Pungent flavor, entering heart and liver meridians, activating blood and dredging meridians, removing blood stasis and alleviating pain. Can be used for treating dysmenorrhea, amenorrhea, puerperal stagnation, traumatic injury, abdominal mass and macula. Has effects in slightly exciting heart, reducing coronary artery resistance, and increasing coronary blood flow and myocardial trophism blood flow; protecting and improving myocardial ischemia, and reducing myocardial infarction range; the red-yellow pigment isolate can resist arrhythmia; the decoction, water extract, safflower yellow, etc. can dilate peripheral blood vessel and lower blood pressure. Can inhibit platelet aggregation, enhance fibrinolysis, and reduce whole blood viscosity.

Compared with the prior similar products, the medicine for treating the discopathy and the cervical vertebra discomfort can quickly relieve the discomfort of the patient, relieve the pain, not aggravate the illness of the patient and effectively eliminate the risk.

The present invention will be further described with reference to the following examples, but the present invention is not limited to the examples.

Detailed Description

The case and treatment statistics listed in the following examples prove that the compatibility of the raw material medicines of the formula is obtained by repeated screening and proportioning. The direct effect of screening and proportioning is reflected in the treatment effect.

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