A kind of Chinese medicine composition with antidepressant effect, food and preparation method thereof

文档序号:1747187 发布日期:2019-11-29 浏览:34次 中文

阅读说明:本技术 一种具有抗抑郁作用的中药组合物、食品及其制备方法 (A kind of Chinese medicine composition with antidepressant effect, food and preparation method thereof ) 是由 刘娜 易斌 王曙宾 罗丽莲 肖艳皎 田军 于 2018-05-21 设计创作,主要内容包括:本发明提供了一种具有抗抑郁作用的食品,包括中药组合物和谷物;所述中药组合物由下列质量份的组分组成:人参1~3份;茯苓2~50份;紫苏2~30份;甘草2~10份;酸枣仁1~50份。本发明所提供的食品以中药及谷物为主要成分,对人体安全无毒副作用,且各组分间的配比合理,使本发明所提供的食品整体效果提高,能有效抗抑郁,同时口感较佳,易被人群接受,适合长期食用,解决了目前抗抑郁产品效果较差的缺陷。(The present invention provides a kind of food with antidepressant effect, including Chinese medicine composition and cereal;The Chinese medicine composition is grouped as by the group of following mass parts: 1~3 part of ginseng;2~50 parts of Poria cocos;2~30 parts of purple perilla;2~10 parts of Radix Glycyrrhizae;1~50 part of semen ziziphi spinosae.Food provided by the present invention is using Chinese medicine and cereal as main component, it is safe to the human body to have no toxic side effect, and the proportion between each component is reasonable, improve food overall effect provided by the present invention, can effective antidepression, while taste good easily receives by crowd, it is suitble to long-term consumption, solves the poor defect of current antidepressant product effect.)

1. a kind of Chinese medicine composition with antidepressant effect, is grouped as by the group of following mass parts:

2. the Chinese medicine composition according to claim 1 with antidepressant effect, which is characterized in that the content of the ginseng For 3 mass parts.

3. the Chinese medicine composition according to claim 1 with antidepressant effect, which is characterized in that the content of the Poria cocos For 15~40 mass parts.

4. the Chinese medicine composition according to claim 1 with antidepressant effect, which is characterized in that the content of the purple perilla For 10~20 mass parts.

5. the Chinese medicine composition according to claim 1 with antidepressant effect, which is characterized in that the content of the Radix Glycyrrhizae For 2~5 mass parts.

6. the Chinese medicine composition according to claim 1 with antidepressant effect, which is characterized in that the semen ziziphi spinosae contains Amount is 10~30 mass parts.

7. the Chinese medicine composition according to claim 1 with antidepressant effect, which is characterized in that by following mass parts Group is grouped as:

8. a kind of food with antidepressant effect, including the described in any item Chinese medicine compositions of claim 1~7 and cereal.

9. the food according to claim 8 with antidepressant effect, which is characterized in that the Chinese medicine composition and cereal Mass ratio be 10~70:30~90.

10. the preparation method of the described in any item food with antidepressant effect of claim 8~9, comprising the following steps:

Each raw material is uniformly mixed and crushes, and crosses 60~80 meshes, obtains uniformly mixed powder.

Technical field

The present invention relates to food technology field more particularly to a kind of Chinese medicine composition with antidepressant effect, food and Preparation method.

Background technique

Depression (Depression) is also known as depressive disorder, low for main clinical characteristics with significant and lasting mental state, It is the main Types of mood disorder.Depression is a kind of common mental disease, and according to the statistics of the World Health Organization, depression has become For the big disease in the world the 4th, it is contemplated that arrive the year two thousand twenty, be likely to become the second largest disease for being only second to coronary heart disease.Depression mainly shows For it is depressed, lose interest, pessimism, with psychomotor agitation or sluggishness, self-assessment is too low, appetite stimulator and Symptoms, the serious persons such as insomnia may occur in which suicidal thought and behavior, seriously endanger the physical and mental health of people.

The cause of disease of depression is unclear at present, but what is certain is that, biology, psychology and all many factors of social environment Take part in the pathogenic process of depression.Biological factor relates generally to heredity, neural biochemistry, neuroendocrine, nerve regneration etc. Aspect.Manhood meets with the life event of irritability, and leads to the important triggering for occurring having the paralepsy of clinical meaning Condition.However, the above factor be not the reciprocation individually to work, between nature-nurture or stress factor, And it is this it is interactive occur time point in depression generating process all have important influence.

Currently, the antidepressant clinically applied is mainly the serotonins weight such as Prozac, Paxil and Sertraline Uptake inhibitor, but since depression mechanism is complicated, induced factor is more, often difficult for the drug of a certain single link To obtain satisfactory effect, there is antidepression spectrum is narrow, side effect is big, medicine valence is high and drug withdrawal is easy to recur etc. in the antidepressants of synthesis mostly Defect.Therefore, the highly-safe efficient antidepressant product of one kind is developed to have a very important significance.

Summary of the invention

In view of this, the technical problem to be solved in the present invention is that providing a kind of Chinese traditional medicine composition with antidepressant effect Object, food and preparation method thereof, Chinese medicine composition and food provided by the present invention have preferable antidepressant effect.

In order to solve the above technical problems, the present invention provides a kind of Chinese medicine compositions with antidepressant effect, by following The group of mass parts is grouped as:

Wherein, ginseng (Panax ginseng C.A.Mey) is herbaceos perennial, and happiness is shady and cool, blade pore-free and Palisade tissue can not retain moisture, and temperature, which is higher than 32 DEG C of blades, to burn, canopy density 0.7-0.8.It blooms within usual 3 years, 5-6 As a result, the month at florescence 5-6, the fruiting period 6-9 month.The nickname of ginseng is kurarinone, Goblin, god grass, King of Herbs, is well-known " east One of northern Triratna ".Ginseng has a variety of health maintenance effects that get rid of illness, and is known as " King of Herbs ".In medical book " legendary god of farming's sheet very early Grass warp " in be considered as, ginseng has the effect of " tonifying five zang organs, soothe the nerves determine soul, stop palpitate with fear, remove pathogenic factor, the happy intelligence development of improving eyesight ", " long term usage make light of one's life by commiting suicide macrobiosis ".Li Shizhen (1518-1593 A.D.) also extremely praises highly ginseng in Compendium of Material Medica, it is believed that it " can control all chronic diseases marked by deficiency of vital energy of male woman ". Modern medicine study and assay show that it is in adjusting people containing a kind of chemical substance for being panaxoside in ginseng Pivot nervous system, heart tonifying, antifatigue, Auto-regulator metabolism etc. have obvious effect, so to treatment nervous system, cardiovascular system A variety of diseases of system, endocrine system and reproductive system have good therapeutic effect.

The content of the ginseng is 1~3 mass parts, preferably 3 mass parts.

Poria cocos is commonly called as Yun Ling, Song Ling, Fu spirit, and to colonize in the fungi plant on pine roots, crust dark brown, the inside is white Color or pink.Multiparasitization is in the root of masson pine or Japanese red pine.Originate in the ground such as Yunnan, Anhui, Hubei, Henan, Sichuan.Ancients claim Poria cocos is " god's medicine when four " because its effect is very extensive, regardless of the four seasons, by it and various compatibility of drugs, regardless of trembling with fear, temperature, wind, Wet all diseases, can play its unique effects." Bencao Jingshu " is recorded: Poria cocos " can open chest internal organs, adjust visceral-qi ... ... bushing benefit Spleen ... " Chinese medicine often improves confused and worried, palpitaition, depression, insomnia, dreaminess etc. with Poria cocos.

The content of the Poria cocos is 2~50 mass parts, preferably 15~40 mass parts, more preferably 15 mass parts.

Chinese traditional herbs of the purple perilla [Perilla frutescens (L.) Britt] as relieving exterior syndrome and dispelling cold, regulating the flow of vital energy and dispeling melancholy, extensively General to be used for clinic, the application especially in depression attracts attention.Purple perilla be Labiatae annual herb plant, leaf, stalk, Fruit can be used as medicine, wherein perilla leaf relieving exterior syndrome and dispelling cold, relieving QI stagnancy in the stomach;Caulis Perillae regulating the flow of QI to ease the stomach, miscarriage prevention and blood;Perilla seed sending down abnormally ascending disappears Phlegm, ease constipation of relievining asthma.Some researches show that the antidepressant effects and adjusting monoamine transmitters of purple perilla, anti-inflammatory anti-oxidant, adjusting inferior colliculus The mechanism such as brain-Pituitary Adrenal (HPA) s function, sedation and analgesia are related.

The content of the purple perilla is 2~30 mass parts, preferably 10~20 mass parts, more preferably 10 mass parts.

Radix Glycyrrhizae is leguminous plant Glycyrrhiza Uralensis, the dry root and rhizome of glycyrrhiza glabra or swollen fruit Radix.It is sweet in flavor, it is mild-natured, Return heart, lung, spleen, stomach meridian, have invigorate the spleen and benefit qi, be clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription and other effects, be clinical The traditional Chinese medicine being most widely used, referred to as " state is old ".Modern pharmacology research shows that Radix Glycyrrhizae has liver protection, anti-inflammatory, anti- The various actives such as bacterium, antiviral, antibechic, antimalarial, anti-oxidant, anticancer, immune regulation, hypoglycemic and anti-platelet aggregation.In Radix Glycyrrhizae Main component be triterpenes and flavonoids, wherein liquiritin is monomer reactivity ingredient important in flavone compound, is had Preferable antidepressant effect.

The content of the Radix Glycyrrhizae is 2~10 mass parts, preferably 2~5 mass parts, more preferably 5 mass parts.

Semen ziziphi spinosae is sour sweet mild-natured, taste sour in taste acting on the liver, color it is red enter the heart, it is sweet can help, be tonifying liver gallbladder, beneficial irritability, nourishing the liver blood, wake up Temper removes vexed, tranquilizing mind, the panacea of tranquilization and nourishing.Acid can restrain, and all medicines share, and can prevent complete just excessively pungent scattered.

The content of the semen ziziphi spinosae is 1~50 mass parts, preferably 10~30 mass parts, more preferably 15 mass parts.

In some embodiments of the invention, the Chinese medicine composition is grouped as by the group of following mass parts:

The preparation method of above-mentioned Chinese medicine composition is to be uniformly mixed each raw material grind into powder.

The present invention has good by being prepared into Chinese medicine composition for ginseng, Poria cocos, purple perilla, Radix Glycyrrhizae, semen ziziphi spinosae compatibility Antidepressant effect.

The present invention also provides a kind of food with antidepressant effect, including above-mentioned Chinese medicine composition and cereal.

The present invention mixes above-mentioned Chinese medicine composition and cereal, food is made, specially a kind of health food.

The cereal is cereal well known to those skilled in the art, including Cereal: as rice class (long-grained nonglutinous rice, japonica rice, Nuo rice), Wheat (wheat, barley, oat, rye), corn, sorghum, grain, broomcorn millet, glutinous millet, buckwheat etc.;Beans bean class: such as soybean, semen viciae fabae, pea Beans, mung bean, red bean, kidney bean etc.;Potato: such as sweet potato is also referred to as sweet potato or sweet potato, potato, Chinese yam, taro, cassava.

In some embodiments of the invention, select oat, rice, corn, millet, purple rice, soybean etc. and other Coarse cereals.

The mass ratio of the Chinese medicine composition and cereal is preferably 10~70:30~90, and more preferably 20~50:50~ 80, further preferably 30:70.

The present invention is prepared into food by combining the Chinese medicine compositions such as ginseng, Poria cocos, purple perilla, Radix Glycyrrhizae, semen ziziphi spinosae with cereal Product, not only taste is good, is suitable for usually eating to solve the problems, such as starvation, but also have good antidepressant effect.

The present invention also provides the preparation methods of the above-mentioned food with antidepressant effect, comprising the following steps:

A) each raw material is uniformly mixed and crushes, and crosses 60~80 meshes, obtains uniformly mixed powder.

For the ease of packed and transported, in some embodiments of the invention, above-mentioned uniformly mixed powder is squeezed Molding, specific:

B) above-mentioned uniformly mixed powder and the water extrusion forming in extruder.

The additive amount of the water is 15wt%~20wt% of powder.

The extruder parameter is preferably as follows:

Screw speed is set as 100-500r/min, and temperature is 100 DEG C -180 DEG C, and maximum working pressure is 0.8- in machine 1.2MPa, the residence time is 5-30s in extruder.

After extrusion forming, it is also preferable to include vacuum packaging, microwave sterilizations etc. routinely to post-process.

The above-mentioned food with antidepressant effect provided by the invention, it is preferably edible at paste with hot water stirs before eating.

The additive amount of hot water can voluntarily be adjusted according to personal taste.

As a specific embodiment, the amount of the above-mentioned food with antidepressant effect provided by the invention is preferred Are as follows: take 10~40g of this product to be added in the hot boiled water of 100~400mL (temperature is 85 DEG C), stirring into paste can take.It is recommended that every It can also once in the morning and once at night take once a day as needed.

Temperature, the dosage of above-mentioned hot water can voluntarily be adjusted according to personal taste.

Compared with prior art, the present invention provides a kind of food with antidepressant effect, including Chinese medicine composition and Cereal;The Chinese medicine composition is grouped as by the group of following mass parts: 1~3 part of ginseng;2~50 parts of Poria cocos;2~30 parts of purple perilla; 2~10 parts of Radix Glycyrrhizae;1~50 part of semen ziziphi spinosae.Food provided by the present invention is safe to the human body using Chinese medicine and cereal as main component It has no toxic side effect, and the proportion between each component is reasonable, improves food overall effect provided by the present invention, it can effectively anti-suppression It is strongly fragrant, while taste good, easily received by crowd, is suitble to long-term consumption, solves the poor defect of current antidepressant product effect.

Specific embodiment

The embodiment of the invention discloses a kind of Chinese medicine compositions with antidepressant effect, food and preparation method thereof.This Field technical staff can use for reference present disclosure, be suitably modified realization of process parameters.In particular, it should be pointed out that all similar Replace and change apparent to those skilled in the art, they are considered as being included in the present invention.Of the invention Product is described by preferred embodiment, and related personnel can obviously not depart from the content of present invention, spirit and scope It is interior product as described herein and method to be modified or appropriate changes and combinations, carry out implementation and application the technology of the present invention.

For a further understanding of the present invention, below with reference to embodiment and comparative example, the present invention is described in detail.

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