阅读说明：本技术 一种高灵敏度氧指示剂及其制备方法 (A kind of high sensitivity oxygen indicator and preparation method thereof ) 是由 应丹青 于 2019-07-31 设计创作，主要内容包括：本发明提供了一种高灵敏度氧指示剂及其制备方法,涉及氧指示剂领域,包括纳米复合纤维素气凝胶以及吸附在其上的氧指示混合成分,所述氧指示混合成分由以下重量百分数的成分组成：还原剂1~1.2%,分散剂2~5%,热稳定剂0.1~0.2%,靛卡红10~15%,靛蓝二磺酸钠10~15%,环糊精余量,本发明高灵敏度氧指示剂检测时间短,显色效果明显,灵敏度搞,适于大范围推广应用于食品、药品的保存。(The present invention provides a kind of highly sensitive oxygen indicators and preparation method thereof, it is related to oxygen indicator field, oxygen including nano-composite fiber element aeroge and absorption on it indicates blending constituent, oxygen instruction blending constituent is by following weight percent at being grouped as: reducing agent 1 ~ 1.2%, dispersing agent 2 ~ 5%, heat stabilizer 0.1 ~ 0.2%, indigo carminum 10 ~ 15%, sodium indigotindisulfonate 10 ~ 15%, cyclodextrin surplus, high sensitivity oxygen indicator detection time of the invention is short, color developing effect is obvious, sensitivity is done, suitable for being applied to food on a large scale, the preservation of drug.)

1. a kind of high sensitivity oxygen indicator, which is characterized in that on it including nano-composite fiber element aeroge and absorption Oxygen indicate blending constituent.

2. high sensitivity oxygen indicator as described in claim 1, which is characterized in that the oxygen instruction blending constituent is by following heavy Amount percentage at being grouped as:

Reducing agent 1 ~ 1.2%

Dispersing agent 2 ~ 5%

Heat stabilizer 0.1 ~ 0.2%

Indigo carminum 10 ~ 15%

Sodium indigotindisulfonate 10 ~ 15%

Cyclodextrin surplus.

3. high sensitivity oxygen indicator as claimed in claim 2, which is characterized in that the reducing agent is organic reducing agent and nothing Machine reducing agent is compounded by weight 1:3 ~ 6；

The organic reducing agent is two mercapto threitols, cysteine, glucose, tyrosine, any one in fructose；

The inorganic reducing agent is sodium sulfite, sodium hydrogensulfite, sodium hypophosphite, iron powder, any one in ferrous sulfate.

4. high sensitivity oxygen indicator as claimed in claim 2, which is characterized in that the dispersing agent is oleyl amine acetic acid Salt, dodecyl quaternary ammonium salt, amino propylamine dioleate, enuatrol, carboxylate, laurilsulfate salt, dodecyl sulphur Any one in hydrochlorate.

5. high sensitivity oxygen indicator as claimed in claim 2, which is characterized in that the heat stabilizer is silicone powder and amber Sour barium is compounded by weight 1:1.

6. high sensitivity oxygen indicator as described in claim 1, which is characterized in that the nano-composite fiber element aeroge The preparation method is as follows:

(1) successively after overpickling, alkali cleaning, will be added in distilled water after wheat crushing, add a certain amount of sodium chlorite and Glacial acetic acid, stirring are warming up to 70 ~ 80 DEG C of heat and boil 2 ~ 5h of processing, filter out and be washed to neutrality, are configured after drying with a certain amount of distilled water At 0.5 ~ 1% suspension, then 30 ~ 50min is handled with ultrasonic cell disruptor ultrasonication and obtains cellulose suspension；

(2) magnesium methoxide, tetraethyl orthosilicate, glycerol are added in dehydrated alcohol, after stirring and evenly mixing, while slowly by the fiber Plain suspension and ammonium hydroxide, which are added dropwise, to be entered, and is dripped 5 ~ 10min of ultrasound after finishing and is removed bubble, reaction solution is transferred in incubator 38 ~ 45 DEG C It reacts 30 ~ 60min to take out, transfers in ultra-low temperature freezer taking-up after freezing 10 ~ 15h and obtain gel semi-finished product；

(3) by obtained gel semi-finished product be immersed in dehydrated alcohol/hexane solution replace 5 ~ 10h after, then be immersed in just oneself 5 ~ 10h is replaced in alkane solution, takes out dries pulverizing.

7. high sensitivity oxygen indicator as described in claim 1, which is characterized in that the temperature of ultra-low temperature freezer is -65 ~ - 55℃。

8. high sensitivity oxygen indicator as described in claim 1, which is characterized in that the body of dehydrated alcohol and n-hexane in solution Product is than being 1 ~ 3:1.

9. a kind of preparation method of oxygen indicator highly sensitive as described in any one of claim 1 ~ 8, which is characterized in that specific Method is as follows:

Oxygen instruction blending constituent is added in distilled water, after mixing evenly, then by the addition of nano-composite fiber element aeroge, and In water bath chader at 40 ~ 50 DEG C oscillation fix 30 ~ 60min make oxygen instruction blending constituent be attached to nano-composite fiber element airsetting On glue, reaction solution is transferred to baking oven and is evaporated water.

Technical field

The present invention relates to oxygen indicator field, and in particular to a kind of high sensitivity oxygen indicator and preparation method thereof.

Background technique

When saving food, drug, the oxygen in air can make food, drug oxidation, to make the quality of food, drug It reduces, therefore, food and the drug quality in preservation reduce in order to prevent, usually by itself and deoxidier etc. together sealed package； Although being all fitted with deoxidier, deoxidizing antistaling agent etc., deoxidier therein in present food many on the market and Key works Drug packing Whether can play the role of effectively anti-oxidation, be not fully aware of for common consumer.

For this purpose, in recent years, having and being enclosed in packing container together using by oxygen indicator and deoxidier etc., by oxygen indicator pair The method for thering is no oxygen to be detected in packaging.Oxygen indicator is that one kind can be according to the variation of tone to oxygen in packing container Whether there is or not the substances for carrying out visuognosis.The tone that ordinary consumer can be presented according to oxygen indicator, directly tells in packaging Whether with the presence of oxygen.

Common oxygen indicator non-refractory on the market at present, the shelf-life is short, and perishable, indicating effect is not very clever It is quick, it is difficult to satisfy the use demand.

Summary of the invention

The object of the present invention is to provide a kind of highly sensitive oxygen indicators and preparation method thereof.

In order to achieve the above object, the present invention is achieved by the following technical programs:

A kind of high sensitivity oxygen indicator, the oxygen instruction including nano-composite fiber element aeroge and absorption on it are mixed into Point.

Further, oxygen instruction blending constituent is by following weight percent at being grouped as:

Reducing agent 1 ~ 1.2%

Dispersing agent 2 ~ 5%

Heat stabilizer 0.1 ~ 0.2%

Indigo carminum 10 ~ 15%

Sodium indigotindisulfonate 10 ~ 15%

Cyclodextrin surplus.

Further, the reducing agent is that organic reducing agent is compounded with inorganic reducing agent by weight 1:3 ~ 6；

The organic reducing agent is two mercapto threitols, cysteine, glucose, tyrosine, any one in fructose；

The inorganic reducing agent is sodium sulfite, sodium hydrogensulfite, sodium hypophosphite, iron powder, any one in ferrous sulfate.

Further, the dispersing agent is oleyl amine acetate, dodecyl quaternary ammonium salt, two oleic acid of amino propylamine Ester, enuatrol, carboxylate, laurilsulfate salt, any one in dodecane sulfonate.

Further, the heat stabilizer is that silicone powder and barium succinate are compounded by weight 1:1.

Further, the nano-composite fiber element aeroge the preparation method is as follows:

(1) successively after overpickling, alkali cleaning, will be added in distilled water after wheat crushing, add a certain amount of sodium chlorite and Glacial acetic acid, stirring are warming up to 70 ~ 80 DEG C of heat and boil 2 ~ 5h of processing, filter out and be washed to neutrality, are configured after drying with a certain amount of distilled water At 0.5 ~ 1% suspension, then 30 ~ 50min is handled with ultrasonic cell disruptor ultrasonication and obtains cellulose suspension；

(2) magnesium methoxide, tetraethyl orthosilicate, glycerol are added in dehydrated alcohol, after stirring and evenly mixing, while slowly by the fiber Plain suspension and ammonium hydroxide, which are added dropwise, to be entered, and is dripped 5 ~ 10min of ultrasound after finishing and is removed bubble, reaction solution is transferred in incubator 38 ~ 45 DEG C It reacts 30 ~ 60min to take out, transfers in ultra-low temperature freezer taking-up after freezing 10 ~ 15h and obtain gel semi-finished product；

(3) by obtained gel semi-finished product be immersed in dehydrated alcohol/hexane solution replace 5 ~ 10h after, then be immersed in just oneself 5 ~ 10h is replaced in alkane solution, takes out dries pulverizing.

Further, the temperature of ultra-low temperature freezer is -65 ~ -55 DEG C.

Further, the volume ratio of dehydrated alcohol and n-hexane is 1 ~ 3:1 in solution.

It is specific as follows the present invention also provides the preparation method of above-mentioned highly sensitive oxygen indicator:

Oxygen instruction blending constituent is added in distilled water, after mixing evenly, then by the addition of nano-composite fiber element aeroge, and In water bath chader at 40 ~ 50 DEG C oscillation fix 30 ~ 60min make oxygen instruction blending constituent be attached to nano-composite fiber element airsetting On glue, reaction solution is transferred to baking oven and is evaporated water.

The working principle of the invention and advantage are:

High sensitivity oxygen indicator of the invention is the oxygen instruction mixing by nano-composite fiber element aeroge and absorption on it At being grouped as, nano-composite fiber element aeroge has nano-porous structure, and porosity is up to 90% or more, and there is super large to compare table The network-like honeycomb of the 3 D stereo of area, each shape honeycomb can be adsorbed for oxygen indicator, make oxygen indicator can There is bigger contact area with oxygen, to have higher reaction speed and discoloration sensitivity, and oxygen of the invention Cyclodextrin is also added in instruction blending constituent, its outer rim is hydrophilic and inner cavity is hydrophobic, and oxygen indicator and airsetting on the one hand can be improved On the other hand the bond strength of glue can provide a hydrophobic binding site as enzyme, various appropriate as main body envelope Object can also improve discoloration sensitivity in conjunction with oxygen molecule and hydrone, heat stabilizer can improve the heat resistance of oxygen indicator Can, it prevents from inactivating because of heated and go bad, present invention high sensitivity oxygen indicator detection time is short, and color developing effect is obvious, sensitive Degree is done, suitable for being applied to the preservation of food, drug on a large scale.

Detailed description of the invention

Fig. 1 is the preparation method of nano-composite fiber element aeroge of the present invention.

Specific embodiment