阅读说明：本技术 基于细菌小细胞的生物药物的电离辐射灭菌以及使用方法 (Ionizing radiation sterilization of biopharmaceuticals based on bacterial minicells and methods of use ) 是由 马修·J·贾卡罗 加里·H·沃德 于 2016-08-03 设计创作，主要内容包括：本申请公开了通过暴露于电离辐射最终灭菌细菌小细胞或包含细菌小细胞的组合物的方法。还公开了最终灭菌的细菌小细胞、包含所述细菌小细胞的药物组合物、以及使用所述细菌小细胞和所述药物组合物的方法。(Disclosed herein are methods of terminally sterilizing bacterial minicells or compositions comprising bacterial minicells by exposure to ionizing radiation. Also disclosed are terminally sterilized bacterial minicells, pharmaceutical compositions comprising the bacterial minicells, and methods of using the bacterial minicells and the pharmaceutical compositions.)