阅读说明：本技术 Withania somnifera提取物提供针对空气污染相关疾病的保护的用途 (Use of extract of Withania SOMNIFERA for protecting against air pollution related diseases ) 是由 伊戈尔·本迪克 贝蒂娜·博兰诺夫 休伯特·保罗·哈格 伯恩德·穆斯勒 纳萨列·理查德 于 2018-04-23 设计创作，主要内容包括：本发明涉及通过使用Withaniasmnifera(南非醉茄)提取物及其Nrf2活化组分醉茄素-A、12-脱氧魏察曼陀罗内酯和Quresimine A进行全身解毒。当被摄入时,细胞内解毒途径中的关键要素转录因子Nrf2导致潜在有毒化合物的消除。与此同时,炎性细胞因子的表达降低。因此,所述提取物一般可用于减少空气污染(并且尤其是微粒空气污染)的不良作用,所述不良作用包括：心血管问题、呼吸系统疾病,以及与空气中传播的颗粒接触的组织的慢性炎症。(the present invention relates to systemic detoxification by using Withania smifera extract and its Nrf2 activating components withanolin-A, 12-deoxywideastmanninolide and Quresimine A. When ingested, the key element in the intracellular detoxification pathway, transcription factor Nrf2, leads to the elimination of potentially toxic compounds. At the same time, the expression of inflammatory cytokines is reduced. Thus, the extract is generally useful for reducing the adverse effects of air pollution (and particulate air pollution in particular), including: cardiovascular problems, respiratory diseases, and chronic inflammation of tissues in contact with airborne particles.)