阅读说明：本技术 一种高效混合悬浮型除草剂 (Efficient mixed suspension type herbicide ) 是由 王雷 陈玲琳 宋增涛 江文 于 2021-07-29 设计创作，主要内容包括：本发明提供了一种高效混合悬浮型除草剂,属于悬浮型除草剂技术领域。所述高效混合悬浮型除草剂的主要有效成分包括(RS)-2-(4-(6-氯-2-喹喔啉氧基)苯氧基)丙酸乙酯和甘草次酸乙酯,为了制备悬浮型除草剂乳油,还需要添加乳化剂、分散剂和溶剂、消泡剂、硅藻土等。本发明的有效成分中(RS)-2-(4-(6-氯-2-喹喔啉氧基)苯氧基)丙酸乙酯占整个除草剂的质量百分比为1～5%,甘草次酸乙酯占整个除草剂的质量百分比为3～10%。本发明的甘草次酸乙酯可以显著提高(RS)-2-(4-(6-氯-2-喹喔啉氧基)苯氧基)丙酸乙酯的除草效果,降低其用量,对环境保护和成本控制方面有深远影响。(The invention provides an efficient mixed suspension type herbicide, and belongs to the technical field of suspension type herbicides. The main effective components of the high-efficiency mixed suspension type herbicide comprise (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate and glycyrrhetinic acid ethyl ester, and in order to prepare the suspension type herbicide emulsifiable solution, an emulsifier, a dispersant, a solvent, an antifoaming agent, diatomite and the like are required to be added. In the active ingredients of the herbicide, the mass percentage of (RS) -ethyl 2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) propionate in the herbicide is 1-5%, and the mass percentage of ethyl glycyrrhetinate in the herbicide is 3-10%. The glycyrrhetinic acid ethyl ester can obviously improve the weeding effect of (RS) -2- (4- (6-chloro-2-quinoxalyloxy) phenoxy) ethyl propionate, reduce the dosage of the (RS) -2- (4- (6-chloro-2-quinoxalyloxy) phenoxy) ethyl propionate, and has profound influence on the aspects of environmental protection and cost control.)

1. A high-efficiency mixed suspension type herbicide is characterized in that: the high-efficiency mixed suspension type herbicide comprises (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate and ethyl glycyrrhetinate.

2. The highly effective mixed suspension type herbicide as claimed in claim 1, wherein: the high-efficiency mixed suspension type herbicide also comprises an emulsifier, a dispersant and a solvent.

3. The highly effective mixed suspension type herbicide as claimed in claim 1, wherein: the mass percentage of the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate in the whole herbicide is 1-5%.

4. The highly effective mixed suspension type herbicide as claimed in claim 1, wherein: the mass percentage of the glycyrrhetinic acid ethyl ester in the whole herbicide is 3-10%.

5. The highly effective mixed suspension type herbicide as claimed in claim 1, wherein: the emulsifier accounts for 5-20% of the whole herbicide by mass.

6. The highly effective mixed suspension type herbicide as claimed in claim 1, wherein: the mass percentage of the dispersing agent in the whole herbicide is 3-10%.

7. The highly effective mixed suspension type herbicide as claimed in claim 1, wherein: the emulsifier comprises an ethyoxyl mixed fatty acid emulsifier, styryl phenyl polyoxyethylene ether and calcium dodecyl benzene sulfonate.

8. The highly effective mixed suspension type herbicide as claimed in claim 1, wherein: the dispersing agent comprises fatty alcohol-polyoxyethylene ether, polyarylphenol polyoxyethylene ether and tristyryl polyoxyether phosphate dispersing agent.

9. The highly effective mixed suspension type herbicide as claimed in claim 1, wherein: the solvent is methyl oleate.

10. The application of glycyrrhiza uralensis is characterized in that: the structural formula of the glycyrrhiza ethyl ester is shown as follows,

the herbicide for synergizing the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate as the effective component reduces the dosage of the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate.

The technical field is as follows:

the invention belongs to the technical field of herbicides, and relates to a high-efficiency mixed suspension type herbicide.

Background art:

herbicides are agents that kill weeds either completely or selectively, and are a class of substances used to destroy or inhibit plant growth. In the herbicide, sodium chlorate, borax, arsenate and trichloroacetic acid have withering effect on any kind of plants, and the effect is influenced by three factors of the herbicide, the plants and environmental conditions. They are divided by action into biocidal and selective herbicides, the selective herbicides being effective in most cases, in particular derivatives of nitrophenol, chlorophenol, carbamic acid. The development of the herbicide in the world is gradually steady, the varieties with high efficiency, low toxicity, broad spectrum and low dosage are mainly developed, and the disposable treatment agent with little environmental pollution gradually becomes the mainstream.

Gramineae is a commonly used selective herbicide with a chemical formula of (RS) -ethyl 2- (4- (6-chloro-2-quinoxalyloxy) phenoxy) propionate and a molecular weight of 372.8, which can selectively control annual and perennial weeds, is mainly used for broad-leaved crops, has excellent control activity on gramineous weeds under any climatic conditions, and is safe for broad-leaved crops. After the foliar application, the weed plants become yellow, the growth stops within 2 days, the primary tissues on the tender leaves and the joints become withered after 5 to 7 days of the foliar application, and the plants die within 14 days; the weeding composition is used for preventing and killing gramineous weeds such as soybean, cotton, beet fields such as alopecurus, wild oat, barnyard grass, crab grass, eleusine indica, green bristlegrass and bermudagrass, and is sprayed at the concentration of 90-150 g/ha, 75-120 g/ha and 120-150 g/ha respectively in the 3-5 leaf period of the weeds, and 450-750 kg of water is sprayed. The diclazera has certain toxicity to human bodies and animals, and has certain safety risk.

Glycyrrhetinic acid (Glycyrrhetinic acid) molecular formula C₃₀H₄₆O₄470.68384, which is one of the main active ingredients in licorice root, and has the effects of resisting bacteria, diminishing inflammation, resisting oxidation, resisting aging, absorbing ultraviolet rays, whitening and brightening skin, removing freckles and the like; has effects in regulating skin immunity, enhancing skin disease resistance, eliminating inflammation, preventing allergy, cleaning skin, preventing melanin generation, and whitening skin. The glycyrrhetinic acid is prepared fromThe glycyrrhizic acid is formed by hydrolysis and removal of sugar acid chain, and the sweetness is 250 times that of the cane sugar. Compared with gramine, the glycyrrhetinic acid has greatly improved safety to human and animals.

At present, the graminaceous herbicide is widely used, the content of the effective component (RS) -2- (4- (6-chloro-2-quinoxalyloxy) phenoxy) ethyl propionate accounts for about 10 percent of that of the emulsifiable concentrate herbicide, and after the synergist is added, the dosage of the effective component (RS) -2- (4- (6-chloro-2-quinoxalyloxy) phenoxy) ethyl propionate is greatly reduced on the premise of not reducing the weeding effect.

The invention content is as follows:

in order to improve the utilization rate of the effective component (RS) -2- (4- (6-chloro-2-quinoxalyloxy) phenoxy) ethyl propionate in the traditional graminicide, reduce the using amount of the herbicide, protect the environment and reduce the pollution and interference of the (RS) -2- (4- (6-chloro-2-quinoxalyloxy) phenoxy) ethyl propionate to the ecological environment, the invention provides an efficient mixed suspension type herbicide which comprises (RS) -2- (4- (6-chloro-2-quinoxalyloxy) phenoxy) ethyl propionate and glycyrrhetinic acid ethyl ester.

Wherein, the high-efficiency mixed suspension type herbicide also comprises an emulsifier, a dispersant and a solvent.

Wherein the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate accounts for 1-5% of the whole herbicide by mass.

Wherein the glycyrrhetinic acid ethyl ester accounts for 3-10% of the whole herbicide by mass.

Wherein the emulsifier accounts for 5-20% of the whole herbicide by mass.

The dispersing agent accounts for 3-10% of the whole herbicide by mass.

Wherein the emulsifier comprises an ethyoxyl mixed fatty acid emulsifier, styryl phenyl polyoxyethylene ether and calcium dodecyl benzene sulfonate.

Wherein the dispersing agent comprises fatty alcohol-polyoxyethylene ether, polyaryl phenol polyoxyethylene ether and tristyryl polyoxyether phosphate dispersing agent.

Wherein the solvent is methyl oleate.

Meanwhile, the prepared liquorice ethyl acetate is used for enhancing the herbicide taking (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate as an effective component, and the using amount of the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate is reduced.

Has the advantages that:

the invention provides a high-efficiency mixed herbicide, the main effective component of which is based on (RS) -2- (4- (6-chloro-2-quinoxalyloxy) phenoxy) ethyl propionate in the gramineous herbicide, the content of the effective component in the traditional gramineous herbicide emulsion is about 10%, and the glycyrrhetinic acid ethyl ester is added in the main component of the gramineous herbicide, so that when the dosage of the (RS) -2- (4- (6-chloro-2-quinoxalyloxy) phenoxy) ethyl propionate is reduced from 7% to 2%, the inhibition effect of the mixed herbicide on weeds is not greatly changed, namely, the utilization rate of the effective component is obviously improved. And if the glycyrrhetinic acid ethyl ester is not added, when the content of the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate alone is 2%, the control effect on weeds is remarkably reduced, and experiments prove that the glycyrrhetinic acid ethyl ester is a synergist, can enhance the utilization rate of the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate, presumably reduce the loss of the glycyrrhetinic acid ethyl ester in the environment, thereby reducing the using amount of the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate and improving the utilization effect of the glycyrrhetinic acid ethyl ester.

The glycyrrhetinic acid ethyl ester is synthesized by glycyrrhetinic acid, has simple preparation method and low cost, is easy to obtain, is an organic substance with low toxicity or no toxicity according to the inference of a chemical structure, is used for replacing part of (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate, reduces the pollution and the damage to the ecological environment, has certain significance for environmental protection, and can reduce the cost of the suspension type mixed herbicide.

Drawings

FIG. 1 is a structural view of ethyl glycyrrhetinate;

FIG. 2 is a synthetic route of glycyrrhetinic acid ethyl ester.

Detailed Description

The present invention will be described in detail with reference to specific examples.

Example 1

The embodiment provides a synergist of a graminicide, the synergist is glycyrrhetinic acid ethyl ester, the structural formula is shown in figure 1, the synergist is prepared from glycyrrhetinic acid, and the preparation method is as follows.

Firstly, completely dissolving glycyrrhetinic acid in DMF, mixing the DMF solution of glycyrrhetinic acid with concentrated sulfuric acid,

wherein the mixing volume ratio of the DMF solution of glycyrrhetinic acid to concentrated sulfuric acid is 1:1, the glycyrrhetinic acid ethyl ester is obtained by refluxing at the temperature of 150-180 ℃ after complete mixing, and the synthetic route is shown in figure 2.

The formula (mass ratio) of the graminaceous herbicide containing the glycyrrhetinic acid ethyl ester is as follows:

in order to verify the synergistic effect of ethyl glycyrrhetinate, the following three formulations are prepared in this example, specifically:

mixed herbicide a: the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate accounts for 2 percent, the glycyrrhetinic acid ethyl ester accounts for 5 percent, the emulsifier is styryl phenyl polyoxyethylene ether accounts for 10 percent, the dispersant is polyarylphenol polyoxyethylene ether accounts for 8 percent, and the methyl oleate accounts for 75 percent.

Mixed herbicide B: 7% of (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate, 10% of styryl phenyl polyoxyethylene ether as an emulsifier, 8% of polyarylphenol polyoxyethylene ether as a dispersant and 75% of methyl oleate.

Mixed herbicide C: the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate accounts for 2 percent, the emulsifier is styryl phenyl polyoxyethylene ether accounts for 10 percent, the dispersant is polyarylphenol polyoxyethylene ether accounts for 8 percent, and the methyl oleate accounts for 80 percent.

Mixed herbicide D: the content of glycyrrhetinic acid ethyl ester is 7%, the content of emulsifier is styryl phenyl polyoxyethylene ether is 10%, the content of dispersant is polyarylphenol polyoxyethylene ether is 8%, and the content of methyl oleate is 75%.

The herbicide is sprayed in a rice field of different divided plots of the same test field in a stem leaf spraying mode respectively, each plot is marked as a region, before administration, the weed amount in each region is basically the same by visual observation, each herbicide is sprayed in different regions at intervals, at least 3 regions are guaranteed to be used for each herbicide, the application amount is 60 ga.i/mu, the control effect of the moleplant seed, the barnyard grass, the cyperaceae and the broadleaf weeds in each region is counted, and the results are shown in the following table.

As can be seen from field experiments of various herbicides, the dosage of the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate is reduced from 7% to 2% after the glycyrrhetinic acid ethyl ester is added, meanwhile, the weed inhibition effect is not greatly changed, and if the glycyrrhetinic acid ethyl ester is not added, the weed prevention effect is remarkably reduced when the content of the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate alone is 2%, and the defect of effective components in the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate is inferred. In the experimental group, the effect of the single use of the glycyrrhetinic acid ethyl ester on the control of the weeds is basically negligible, so that the conclusion that the glycyrrhetinic acid ethyl ester is only a synergist and can enhance the (RS) -2-

The utilization of ethyl (4- (6-chloro-2-quinoxalinyloxy) phenoxy) propionate presumably reduces its loss in the environment, thereby reducing the amount of ethyl (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) propionate used.

Example 2

This example provides suspension type mixed herbicide emulsifiable concentrates of different formulations, each as follows:

the formula I is as follows: the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate accounts for 1 percent, the glycyrrhetinic acid ethyl ester accounts for 3 percent, the emulsifier is an ethoxy mixed fatty acid emulsifier (VO/02N) accounts for 5 percent, the dispersant is a tristyryl polyoxyether phosphate dispersant (Soprophor FD) accounts for 3 percent, and the methyl oleate accounts for 88 percent.

And a second formula: 5 percent of (RS) -2- (4- (6-chloro-2-quinoxalyloxy) phenoxy) ethyl propionate, 10 percent of glycyrrhetinic acid ethyl ester, 20 percent of emulsifier which is ethoxy mixed fatty acid emulsifier (VO/02N), 10 percent of dispersant which is tristyryl polyoxyether phosphate dispersant (Soprophor FD), and 55 percent of methyl oleate.

And the formula III: the (RS) -2- (4- (6-chloro-2-quinoxalinyloxy) phenoxy) ethyl propionate accounts for 2 percent, the glycyrrhetinic acid ethyl ester accounts for 8 percent, the emulsifier is styryl phenyl polyoxyethylene ether accounts for 10 percent, the dispersant is fatty alcohol polyoxyethylene ether accounts for 5 percent, and the methyl oleate accounts for 75 percent.

The formula four: 3 percent of (RS) -2- (4- (6-chloro-2-quinoxalyloxy) phenoxy) ethyl propionate, 3 percent of glycyrrhetinic acid ethyl ester, 5 percent of dodecyl benzene sulfonic acid calcium as an emulsifier, 3 percent of polyarylphenol polyoxyethylene ether as a dispersant and 55 percent of methyl oleate.