阅读说明：本技术 一种高性能超声刀及其制备方法 (High-performance ultrasonic knife and preparation method thereof ) 是由 刘国栋 唐能 李宜雄 姚磊 李玺 于 2021-08-17 设计创作，主要内容包括：本发明涉及一种高性能超声刀及其制备方法,为了提高超声手术刀的疲劳强度,延长疲劳寿命,降低手术风险,本发明先后对超声手术刀衬底材料TC4合金进行气体渗氮处理和液氮深冷处理,研究表明,单独的气体渗氮处理可以提高TC4合金的耐腐蚀性能,但是对疲劳强度的提高不明显,通过渗氮后续的深冷处理,可对TC4合金的疲劳强度产生积极影响,通过选择合适的深冷处理时间,可使超声手术刀的疲劳循环次数提升一个数量级,进而显著延长其疲劳寿命。(The invention relates to a high-performance ultrasonic scalpel and a preparation method thereof, aiming at improving the fatigue strength of the ultrasonic scalpel, prolonging the fatigue life and reducing the operation risk, the invention carries out gas nitriding treatment and liquid nitrogen cryogenic treatment on a TC4 alloy substrate material of the ultrasonic scalpel in sequence, and researches show that the corrosion resistance of the TC4 alloy can be improved by the single gas nitriding treatment, but the improvement of the fatigue strength is not obvious, the fatigue strength of the TC4 alloy can be positively influenced by the subsequent cryogenic treatment of nitriding, and the fatigue cycle number of the ultrasonic scalpel can be improved by one order of magnitude by selecting the proper cryogenic treatment time, so that the fatigue life of the ultrasonic scalpel is obviously prolonged.)

1. A preparation method of a high-performance ultrasonic knife is characterized by comprising the following steps:

A. selecting a titanium alloy as a substrate material, and removing irregular parts on the surface of the substrate material through machining;

B. sequentially polishing, pickling, deoiling, cleaning and drying the substrate material for later use;

C. putting the dried substrate into a gas nitriding furnace, introducing ammonia decomposition gas for gas nitriding, raising the temperature to 600-650 ℃ at the speed of 10-15 ℃/min during nitriding, and then preserving heat for 8-9 h;

D. putting the nitrided substrate into a vacuum annealing furnace for vacuum annealing, wherein the annealing temperature is 350-400 ℃, the annealing time is 2-2.5h, and then cooling to room temperature along with the furnace;

E. and (3) placing the cooled substrate into liquid nitrogen at the temperature of-196 ℃ for cryogenic treatment.

2. A method of making according to claim 1, wherein: the titanium alloy is TC4 alloy.

3. A method of making according to claim 1, wherein: and the sanding is performed by using sand paper with the precision of 400#, 800# and 1200#, respectively.

4. A method of making according to claim 1, wherein: and 15% hydrochloric acid solution is selected for pickling.

5. A method of making according to claim 1, wherein: and 20% sodium carbonate solution is selected for oil removal.

6. A method of making according to claim 1, wherein: the cleaning is performed by using deionized water, and the drying is performed in a nitrogen atmosphere.

7. A method of making according to claim 1, wherein: the time of the cryogenic treatment is about 5 to 6.7 hours.

8. A high performance ultrasonic blade produced by the method of any one of claims 1 to 7.

Technical Field

The invention relates to the field of medical scalpels, in particular to a high-performance ultrasonic scalpel and a preparation method thereof.

Background

An ultrasonic scalpel is a surgical instrument commonly used in the surgical operation at present, and mainly comprises an ultrasonic electric power source and an ultrasonic vibration system. The ultrasonic vibration system comprises an ultrasonic transducer, a concentrator and a cutter head. The ultrasonic scalpel mainly utilizes ultrasonic cavitation and strong mechanical effect to cut and destroy biological tissues. Currently, there are three types of ultrasonic surgical knives, cutting type, suction type and degreasing type. In the operation process, the ultrasonic vibration is easy to destroy the cell tissue with high water content, and is not easy to damage blood vessels, lymph, nerve fibers and the like containing high collagen, so that the ultrasonic operation cutter selectively retains the advantages of important tissue structures, small wound, less bleeding, clear operative field and the like. At present, ultrasonic surgical knives have been widely used in medical scenes of liver, gallbladder and spleen operations in general surgery, brain surgery, thoracic surgery, urinary surgery, obstetrics and gynecology, and the like.

However, after the material is subjected to alternating loads, fatigue failure can occur after multiple cycles of loading, even if the stress values do not exceed the strength limits of the material. Because the ultrasonic scalpel needs to work under the ultrasonic frequency of about 55kHz, the ultrasonic scalpel can experience ultrahigh cycle load circulation in a short time, and further fatigue fracture is easy to occur, and even medical accidents are caused. In view of the above, how to improve the fatigue life of the ultrasonic scalpel is a problem to be solved urgently.

Disclosure of Invention

Aiming at the problems in the prior art, the invention aims to provide a high-performance ultrasonic scalpel and a preparation method thereof.

In order to achieve the purpose, the preparation method of the high-performance ultrasonic knife provided by the invention comprises the following steps:

A. selecting a titanium alloy as a substrate material, and removing irregular parts on the surface of the substrate material through machining;

B. sequentially polishing, pickling, deoiling, cleaning and drying the substrate material for later use;

C. putting the dried substrate into a gas nitriding furnace, introducing ammonia decomposition gas for gas nitriding, raising the temperature to 600-650 ℃ at the speed of 10-15 ℃/min during nitriding, and then preserving heat for 8-9 h;

D. putting the nitrided substrate into a vacuum annealing furnace for vacuum annealing, wherein the annealing temperature is 350-400 ℃, the annealing time is 2-2.5h, and then cooling to room temperature along with the furnace;

E. and (3) placing the cooled substrate into liquid nitrogen at the temperature of-196 ℃ for cryogenic treatment.

Further, the titanium alloy is a TC4 alloy.

Further, the sanding is performed by using sand paper with the precision of 400#, 800# and 1200#, respectively.

Further, a 15% hydrochloric acid solution is selected for the acid washing.

Further, 20% sodium carbonate solution is selected for oil removal.

Further, deionized water is selected for cleaning, and drying is performed in a nitrogen atmosphere.

Further, the time of the cryogenic treatment is about 5 to 6.7 hours.

Further, the invention also provides a high-performance ultrasonic knife which is prepared by the method.

In order to improve the fatigue strength of the ultrasonic scalpel, prolong the fatigue life and reduce the operation risk, the invention carries out gas nitriding treatment and liquid nitrogen cryogenic treatment on the TC4 alloy as the substrate material of the ultrasonic scalpel in sequence, and researches show that the corrosion resistance of the TC4 alloy can be improved by the single gas nitriding treatment, but the improvement of the fatigue strength is not obvious, the fatigue strength of the TC4 alloy can be positively influenced by the subsequent cryogenic treatment of nitriding, and the fatigue cycle times of the ultrasonic scalpel can be improved by one order of magnitude by selecting the proper cryogenic treatment time, so that the fatigue life of the ultrasonic scalpel is obviously prolonged.

Detailed Description

The technical effects of the present invention are demonstrated below by specific examples, but the embodiments of the present invention are not limited thereto.

Example 1

A. Selecting TC4 alloy as a substrate material, and removing irregular parts of the surface of the substrate material by machining;

B. sequentially polishing, pickling, deoiling, cleaning and drying a substrate material for later use, wherein abrasive paper with the precision of No. 400, No. 800 and No. 1200 is selected for polishing, 15% hydrochloric acid solution is selected for pickling, 20% sodium carbonate solution is selected for deoiling, deionized water is selected for cleaning, and drying is performed in a nitrogen atmosphere;

C. putting the dried substrate into a gas nitriding furnace, introducing ammonia decomposition gas for gas nitriding, raising the temperature to 650 ℃ at the speed of 10 ℃/min during nitriding, and then preserving the temperature for 8 hours;

D. putting the nitrided substrate into a vacuum annealing furnace for vacuum annealing, wherein the annealing temperature is 400 ℃, the annealing time is 2 hours, and then cooling the substrate to room temperature along with the furnace;

E. and (3) placing the cooled substrate into liquid nitrogen at the temperature of-196 ℃ for cryogenic treatment for 5 h.

Example 2

A. Selecting TC4 alloy as a substrate material, and removing irregular parts of the surface of the substrate material by machining;

B. sequentially polishing, pickling, deoiling, cleaning and drying a substrate material for later use, wherein abrasive paper with the precision of No. 400, No. 800 and No. 1200 is selected for polishing, 15% hydrochloric acid solution is selected for pickling, 20% sodium carbonate solution is selected for deoiling, deionized water is selected for cleaning, and drying is performed in a nitrogen atmosphere;

C. putting the dried substrate into a gas nitriding furnace, introducing ammonia decomposition gas for gas nitriding, raising the temperature to 650 ℃ at the speed of 10 ℃/min during nitriding, and then preserving the temperature for 8 hours;

D. putting the nitrided substrate into a vacuum annealing furnace for vacuum annealing, wherein the annealing temperature is 400 ℃, the annealing time is 2 hours, and then cooling the substrate to room temperature along with the furnace;

E. and (3) placing the cooled substrate into liquid nitrogen at the temperature of-196 ℃ for cryogenic treatment for 5.3 h.

Example 3

A. Selecting TC4 alloy as a substrate material, and removing irregular parts of the surface of the substrate material by machining;

B. sequentially polishing, pickling, deoiling, cleaning and drying a substrate material for later use, wherein abrasive paper with the precision of No. 400, No. 800 and No. 1200 is selected for polishing, 15% hydrochloric acid solution is selected for pickling, 20% sodium carbonate solution is selected for deoiling, deionized water is selected for cleaning, and drying is performed in a nitrogen atmosphere;

C. putting the dried substrate into a gas nitriding furnace, introducing ammonia decomposition gas for gas nitriding, raising the temperature to 650 ℃ at the speed of 10 ℃/min during nitriding, and then preserving the temperature for 8 hours;

D. putting the nitrided substrate into a vacuum annealing furnace for vacuum annealing, wherein the annealing temperature is 400 ℃, the annealing time is 2 hours, and then cooling the substrate to room temperature along with the furnace;

E. and (3) placing the cooled substrate into liquid nitrogen at the temperature of-196 ℃ for cryogenic treatment for 5.8 h.

Example 4

A. Selecting TC4 alloy as a substrate material, and removing irregular parts of the surface of the substrate material by machining;

B. sequentially polishing, pickling, deoiling, cleaning and drying a substrate material for later use, wherein abrasive paper with the precision of No. 400, No. 800 and No. 1200 is selected for polishing, 15% hydrochloric acid solution is selected for pickling, 20% sodium carbonate solution is selected for deoiling, deionized water is selected for cleaning, and drying is performed in a nitrogen atmosphere;

C. putting the dried substrate into a gas nitriding furnace, introducing ammonia decomposition gas for gas nitriding, raising the temperature to 650 ℃ at the speed of 10 ℃/min during nitriding, and then preserving the temperature for 8 hours;

D. putting the nitrided substrate into a vacuum annealing furnace for vacuum annealing, wherein the annealing temperature is 400 ℃, the annealing time is 2 hours, and then cooling the substrate to room temperature along with the furnace;

E. and (3) placing the cooled substrate into liquid nitrogen at the temperature of-196 ℃ for cryogenic treatment for 6.2 h.

Example 5

A. Selecting TC4 alloy as a substrate material, and removing irregular parts of the surface of the substrate material by machining;

B. sequentially polishing, pickling, deoiling, cleaning and drying a substrate material for later use, wherein abrasive paper with the precision of No. 400, No. 800 and No. 1200 is selected for polishing, 15% hydrochloric acid solution is selected for pickling, 20% sodium carbonate solution is selected for deoiling, deionized water is selected for cleaning, and drying is performed in a nitrogen atmosphere;

C. putting the dried substrate into a gas nitriding furnace, introducing ammonia decomposition gas for gas nitriding, raising the temperature to 650 ℃ at the speed of 10 ℃/min during nitriding, and then preserving the temperature for 8 hours;

D. putting the nitrided substrate into a vacuum annealing furnace for vacuum annealing, wherein the annealing temperature is 400 ℃, the annealing time is 2 hours, and then cooling the substrate to room temperature along with the furnace;

E. and (3) placing the cooled substrate into liquid nitrogen at the temperature of-196 ℃ for cryogenic treatment for 6.7 h.

Comparative example 1

A. Selecting TC4 alloy as a substrate material, and removing irregular parts of the surface of the substrate material by machining;

B. sequentially polishing, pickling, deoiling, cleaning and drying a substrate material for later use, wherein abrasive paper with the precision of No. 400, No. 800 and No. 1200 is selected for polishing, 15% hydrochloric acid solution is selected for pickling, 20% sodium carbonate solution is selected for deoiling, deionized water is selected for cleaning, and drying is performed in a nitrogen atmosphere;

C. putting the dried substrate into a gas nitriding furnace, introducing ammonia decomposition gas for gas nitriding, raising the temperature to 650 ℃ at the speed of 10 ℃/min during nitriding, and then preserving the temperature for 8 hours;

D. putting the nitrided substrate into a vacuum annealing furnace for vacuum annealing, wherein the annealing temperature is 400 ℃, the annealing time is 2 hours, and then cooling the substrate to room temperature along with the furnace;

E. and (3) placing the cooled substrate into liquid nitrogen at the temperature of-196 ℃ for cryogenic treatment for 3 h.

Comparative example 2

A. Selecting TC4 alloy as a substrate material, and removing irregular parts of the surface of the substrate material by machining;

B. sequentially polishing, pickling, deoiling, cleaning and drying a substrate material for later use, wherein abrasive paper with the precision of No. 400, No. 800 and No. 1200 is selected for polishing, 15% hydrochloric acid solution is selected for pickling, 20% sodium carbonate solution is selected for deoiling, deionized water is selected for cleaning, and drying is performed in a nitrogen atmosphere;

C. putting the dried substrate into a gas nitriding furnace, introducing ammonia decomposition gas for gas nitriding, raising the temperature to 650 ℃ at the speed of 10 ℃/min during nitriding, and then preserving the temperature for 8 hours;

D. putting the nitrided substrate into a vacuum annealing furnace for vacuum annealing, wherein the annealing temperature is 400 ℃, the annealing time is 2 hours, and then cooling the substrate to room temperature along with the furnace;

E. and (3) placing the cooled substrate into liquid nitrogen at the temperature of-196 ℃ for cryogenic treatment for 9 h.

Hereinafter, the experimental samples of examples 1 to 5 and comparative examples 1 to 2 were subjected to a fatigue test at the operating frequency (55kHz) of an ultrasonic scalpel, and the fatigue life thereof was evaluated based on the number of cycles at which fatigue fracture occurred in each sample, and specific experimental data are shown in Table 1, in which the blank group was TC4 alloy which was not subjected to nitriding treatment and cryogenic treatment.

TABLE 1 number of cycles for each experimental sample

Numbering	Number of cycles
		Example 1	3.17*109
Example 2	5.11*109
		Example 3	5.88*109
Example 4	6.96*109
		Example 5	6.13*109
Comparative example 1	3.26*108
		Comparative example 2	5.39*108
Blank group	1.21*108

The above description is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, several modifications and variations can be made without departing from the technical principle of the present invention, and these modifications and variations should also be regarded as the protection scope of the present invention.