阅读说明：本技术 一种具有减肥功效的外用复方组合物 (External compound composition with weight-losing effect ) 是由 梁珍宁 梁明 于 2021-09-24 设计创作，主要内容包括：本发明涉及一种复方组合物,尤其是对腹部肥胖具有减脂效果的外用复方组合物。本发明所述的具有减肥功效的外用复方组合物由以下重量份的成分组成：白胡椒280-320g、北五味子150-170g、红景天35-45g、红花35-45g、酒精1000-1500ml、丙二醇220-260ml。其制备方法由以下步骤组成：一、将重量配比的白胡椒、北五味子、红景天、红花粉碎至60目；二、加入酒精常温浸泡10-15日,过滤；三、在步骤二的过滤液中加入丙二醇搅拌均匀即可。临床观察结果表明本发明具有祛脂消脂,行气化滞等功效,其通过皮肤吸收,使药性直达病所。总有效率96.4％,疗效确切,无任何明显不良反应。(The invention relates to a compound composition, in particular to an external compound composition with a fat reducing effect on abdominal obesity. The external compound composition with the weight-losing effect consists of the following components in parts by weight: 320g of white pepper 280-. The preparation method comprises the following steps: firstly, grinding white pepper, fructus schisandrae chinensis, rhodiola rosea and safflower in weight ratio to 60 meshes; secondly, adding alcohol, soaking for 10-15 days at normal temperature, and filtering; and thirdly, adding propylene glycol into the filtrate obtained in the second step and uniformly stirring. Clinical observation results show that the invention has the effects of removing fat and reducing fat, promoting qi circulation and removing food retention, and the like, and the medicine can directly reach the focus of diseases by being absorbed by skin. The total effective rate is 96.4 percent, the curative effect is exact, and no obvious adverse reaction exists.)

1. An external compound composition with a weight-losing effect is characterized by comprising the following components in parts by weight: 320g of white pepper 280-.

2. The externally-applied compound composition with the weight-losing effect as claimed in claim 1, which is characterized by comprising the following components in parts by weight: 300g of white pepper, 160g of fructus schisandrae chinensis, 40g of rhodiola rosea, 40g of safflower, 1200ml of alcohol and 240ml of propylene glycol.

3. The combination composition of any one of claims 1-2, wherein the alcohol is 95 degree alcohol.

4. The compound composition for external use with the effect of losing weight according to any one of claims 1 to 2, characterized in that the preparation method thereof consists of the following steps:

firstly, grinding white pepper, fructus schisandrae chinensis, rhodiola rosea and safflower in weight ratio to 60 meshes;

secondly, adding alcohol, soaking for 10-15 days at normal temperature, and filtering;

and thirdly, adding propylene glycol into the filtrate obtained in the second step and uniformly stirring.

Technical Field

The invention relates to a compound composition, in particular to an external compound composition with a fat reducing effect on abdominal obesity.

Technical Field

Chinese patent application No. 93104348.4 discloses a camouflage tea, belonging to a health tea, which is composed of high-quality fermented tea, natural sea buckthorn tender bud leaves and traditional Chinese medicines of cinnamon, stir-fried fennel, white pepper and the like with the functions of balancing yin and yang and warming menstruation. The present invention has certain effect on eliminating off-site discomfort, promoting appetite, building body, reducing weight and giving up drugs.

The composition with the weight-losing function is an oral preparation.

Chinese patent application No. 202010379727.0 discloses an external spray containing Chinese medicinal extracts for losing weight and slimming and a preparation method thereof, which comprises the following components in percentage by volume: 6-10% of distilled water, 4-7% of glycerol, 3-5% of propylene glycol, 3-5% of ethanol, 3.0-4.5% of vanillyl butyl ether, 0.1-0.3% of methylparaben and 69-82% of a traditional Chinese medicine extract; wherein the traditional Chinese medicine extract comprises the following components in parts by weight: 5-7 parts of rheum officinale, 10-13 parts of folium artemisiae argyi, 14-17 parts of radix linderae, 15-17 parts of rhizoma atractylodis lanceae, 12-15 parts of turmeric and 12-14 parts of coptis chinensis. The external spray for losing weight is scientific in compatibility, reasonable in formula and convenient and fast to use, can act on a human body quickly, and has the purposes of dredging the channels and collaterals of the human body, strengthening the blood circulation of the human body, increasing the metabolism of the human body, promoting the detoxification and oil discharge of human intestinal tracts, and removing impurity toxins in the human body so as to achieve the purpose of losing weight.

Chinese patent application No. 202010066282.0 discloses a Chinese medicinal composition for treating abdominal obesity, and a preparation and an external preparation thereof, wherein the Chinese medicinal composition comprises 1-3 parts of rheum officinale, 1-3 parts of radix puerariae, 3-5 parts of divaricate saposhnikovia root, 3-5 parts of angelica sinensis, 0.5-1.5 parts of rhizoma alismatis, 0.5-1.5 parts of mint, 0.05-0.15 part of menthol, 0.01-0.03 part of divaricate saposhnikovia root volatile oil and 0.01-0.03 part of angelica sinensis volatile oil.

Chinese patent application No. 201911034622.5 discloses an external Chinese herbal medicine formula with weight-losing effect, which comprises the following raw materials of 18-24 parts by weight of rhubarb; 14-17 parts of salvia miltiorrhiza; 9-11 parts of wild hawthorn; 8-11 parts of semen cassiae; 14-17 parts of folium artemisiae argyi; 9-11 parts of safflower; 11-14 parts of a Sichuan aromatic hydrocarbon; 7-10 parts of pseudo-ginseng; 4-6 parts of liquorice; 8-10 parts of bunge cherry seeds; 9-13 parts of rhizoma atractylodis; 8-12 parts of rhizoma alismatis; 9-11 parts of Chinese olive; 10-14 parts of sea buckthorn; 8-11 parts of sophora flower bud; 9-11 parts of senna leaves; 9-13 parts of green tea; 8-12 parts of fructus cannabis.

Chinese patent application No. 201910972006.8 discloses an externally-applied conditioning and weight-reducing bag suitable for phlegm-dampness constitution and a use method thereof, which comprises the following components in percentage by weight: 10-30% of perilla fruit, 5-20% of rhizoma atractylodis, 5-20% of bighead atractylodes rhizome, 20-50% of lotus leaf, 15-50% of hawthorn leaf, 10-30% of poria cocos, 5-20% of rheum officinale and 5-20% of borneol; in addition, 10-30% of dried orange peel, 5-30% of gynostemma pentaphylla and 5-20% of camphor can also be added.

The external composition with the weight-losing function basically takes rhubarb and kudzu root as main components and volatile components as auxiliary components.

Disclosure of Invention

The invention aims to provide a compound composition with simple components and a weight-losing function.

The invention also aims to provide a preparation method of the compound composition.

The external compound composition with the weight-losing effect consists of the following components in parts by weight: 320g of white pepper 280-.

The alcohol is 95-degree alcohol.

The preparation method of the external compound composition with the weight-losing effect comprises the following steps:

firstly, grinding white pepper, fructus schisandrae chinensis, rhodiola rosea and safflower in weight ratio to 60 meshes;

secondly, adding alcohol, soaking for 10-15 days at normal temperature, and filtering;

and thirdly, adding propylene glycol into the filtrate obtained in the second step and uniformly stirring.

White pepper itself is a seasoning, and is widely used in life. Its main component is piperine, and also contains a certain quantity of aromatic oil, crude protein and starch, and can be used for removing fishy smell in food at ordinary times, so that it can play a certain role of promoting appetite. From the perspective of traditional Chinese medicine, pepper is warm in nature and has the efficacy of warming the middle-jiao and dispelling cold after being eaten. Has certain inhibiting effect on abdominal pain, diarrhea, nausea and vomiting caused by cold accumulation in stomach and intestine, and is favorable for absorption of nutrient substances.

The effects of the schisandra chinensis are astringing and inducing astringency, tonifying qi and promoting the production of body fluid, tonifying the kidney and calming the heart. Clinically, the actions of schisandrae are mainly seen in the following points: 1. for patients with chronic diarrhea, such as enteritis, the symptoms of enteritis can be obviously relieved by the astringency and astringency of schisandra chinensis. 2. Pulmonary diseases are mainly patients with chronic bronchitis, obstructive emphysema and other perennial diseases and asthenic asthma. 3. The heart problem is often matched with other medicines, such as radix ophiopogonis and salvia miltiorrhiza, to treat coronary heart disease and arrhythmia. 4. Sweating is commonly referred to as spontaneous sweating and night sweat. 5. Thirst due to diabetes. 6. Spermatorrhea, spermatorrhea and other kidney functions in men.

Rhodiola rosea is a traditional Chinese medicine with a very long history of traditional Chinese medicines, and is listed as a medicine top grade in the 'Shen nong herbal Jing' which is the earliest known work in traditional Chinese medicine, so that the rhodiola rosea is considered to have a very good tonifying effect and can prolong life after being taken for a long time. Rhodiola rosea has good tonifying effects on lung, kidney, spleen and stomach, can tonify qi, enrich blood and replenish essence and blood. Modern researches find that rhodiola rosea contains a great amount of amino acids and anti-aging substances, can eliminate free radicals in vivo, regulate immune function balance, inhibit abnormal immunity in vivo, and simultaneously assist in improving in vivo regulatory immunity, and has the function of improving resistance for weak people when being taken.

Safflower, being pungent in flavor and warm in nature, has the effects of activating blood and stimulating the menstrual flow, dissipating blood stasis and relieving pain, and is clinically applied to the following symptoms: firstly, amenorrhea due to blood stagnation, dysmenorrhea, postpartum abdominal stagnant pain; second, abdominal mass; thirdly, chest stuffiness and pains, blood stasis and abdominal pain, hypochondriac pain; fourthly, the macula is dark in color due to stasis; fifthly, regurgitation, stasis headache, dizziness, apoplexy and hemiplegia, etc.

From the attributes of the above components, it seems that there is little connection to obesity, especially abdominal obesity, and most of these food materials or medicinal materials are mainly taken orally.

Obesity is roughly divided into abdominal obesity and hip obesity, wherein the abdominal obesity is serious in harm, and the main harm is to a cardiovascular system, such as cardiac load increase, blood volume increase, accelerated arteriosclerosis, cardiac dysfunction, hypertension and the like; for endocrine system, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, diabetes, liver disease, etc. are caused; for the respiratory system, sleep apnea can be caused; in other aspects, tumors, polycystic ovary syndrome, and the like can be caused. Especially women with an abdominal overweight are at higher risk of arterial embolism than those with general obesity or obesity elsewhere.

The method for reducing weight of the abdominal obesity patients comprises western medicine type or Chinese medicine type, most western medicines take medicines, the effect is possibly faster, but the problems of side effect and rebound are brought. The traditional Chinese medicine mainly adopts methods of acupuncture and cupping, running exercise, diet and delisting, and the like, and the problems of difficult insistence and rebound can also occur.

The traditional Chinese medicine of the existing external slimming preparation mainly adopts rhubarb, coptis and kudzu root, is supplemented with volatile components, and has huge and complex formula. The invention develops a new method, adopts the compatibility of white pepper, schisandra chinensis, rhodiola rosea and safflower which is not reported, has simple formula but exact and obvious effect and does not have any obvious adverse reaction. The invention mainly gives full play to the effects of promoting blood circulation, removing blood stasis and eliminating dampness of the white pepper, the fructus schisandrae, the rhodiola rosea and the safflower, and particularly the white pepper occupies the main position in the formula and is supplemented with other ingredients to play the effects of removing fat, reducing fat and promoting qi circulation and stagnation.

The clinical curative effect observation and summary of the abdomen slimming disclosed by the invention are as follows:

the weight-loss essential oil of example 1 was provided by Kunming Yumo Biotechnology, Inc.

First, clinical data

1. General data

The group had 83 women, 76 men and 7 women; age 59 years maximum and 24 years minimum. The body mass is 110kg at most and 68kg at least.

2. Inclusion criteria

(1) And calculating to obtain the object of treatment for more than 20% according to the relationship between the body mass and the body length of the normal human body. The average body mass of patients in this group exceeded 26%.

(2) The measuring and calculating method comprises the following steps: the height, waist, hip circumference and weight of the patient are determined in the early morning on an empty stomach, and the patient who meets the selection condition is listed as the treatment object. After 1 treatment course, the same weighing apparatus is used for reexamination and recording.

3. Method of treatment

(1) The external treatment method in the embodiment 1 is adopted for treatment, the whole belly is kneaded (rubbed) 3 times a day, each time lasts for 15-20 minutes, and 30 days are a treatment course.

(2) And (5) taking a matching measure. The patient can do the push-up or sit-up exercise indoors during the morning running and night. Order patients to eat high-fat and sugar foods, eat vegetables and drink tea and the like less frequently.

Second, standard of therapeutic effect

And (3) curing: recovering the normal body quality; the effect is shown: the body mass is reduced by more than 3kg, and the waist circumference is reduced by more than 5 cm; the method has the following advantages: the weight of the body is reduced by less than 2-3 kg, and the waist circumference is reduced by more than 3 cm; and (4) invalidation: the body mass is reduced by less than 2kg or no change, and the waist circumference is reduced by less than 1cm or no change.

Thirdly, observation of curative effect

83 cases are all effective, wherein 15 cases are cured and account for 18 percent; 49 cases with obvious effect, 59 percent; the effective 18 cases account for 22.8%. See table 1.

TABLE 1 therapeutic results

Fourth, adverse reaction observation

Example 1 in the process of externally treating abdominal obesity, only 3 cases of patients have skin allergy, and the rash naturally disappears after the patients stop taking the medicine for 1 day, so the use is safe.

Seven, summary

Example 1 has the effects of removing fat and reducing fat, promoting qi circulation and removing food retention, and the like, and can make the medicine directly reach the focus through skin absorption. The clinical observation result shows that the total effective rate of the example 1 is 96.4 percent, the curative effect is exact, and no obvious adverse reaction exists.

Detailed Description

Example 1:

taking 300g of white pepper, 160g of fructus schisandrae, 40g of rhodiola rosea and 40g of safflower, respectively crushing to 60 meshes, and mixing. Adding 1200ml of 95-degree alcohol, soaking at normal temperature for 10 days, filtering, adding 240ml of propylene glycol into the filtrate, stirring uniformly, and bottling.