阅读说明：本技术 一种新型分离装置 (Novel separation device ) 是由 谢文明 于 2021-09-02 设计创作，主要内容包括：本发明公开一种新型分离装置,包括第一容器、第二容器、密封盖和驱动机构；第一容器具有开口向上的第一容腔；第二容器活动配合在第一容腔内,其设置有开口向上的第二容腔,且第二容器的底面设置有引流管,引流管使得第二容器的底面与第二容腔连通；密封盖盖合在第一容腔的开口处；驱动机构设置在密封盖上并与第二容器传动连接,用于驱动第二容器在第一容器内进行升降运动。本发明可通过操作驱动机构使得第二容器在第一容器内进行升降运动,当第二容器下降时,可以将第一容腔内盛装的离心后的液体样本的上层液体挤入引流管,并通过引流管流至第二容腔内,实现上层液体与其他液体样本的分离,更方便抽取,不容易掺入杂质,易于单手操作。(The invention discloses a novel separation device, which comprises a first container, a second container, a sealing cover and a driving mechanism, wherein the first container is connected with the second container through a pipeline; the first container is provided with a first cavity with an upward opening; the second container is movably matched in the first cavity and is provided with a second cavity with an upward opening, the bottom surface of the second container is provided with a drainage tube, and the drainage tube enables the bottom surface of the second container to be communicated with the second cavity; the sealing cover covers the opening of the first cavity; the driving mechanism is arranged on the sealing cover, is in transmission connection with the second container and is used for driving the second container to perform lifting movement in the first container. The second container can be lifted in the first container by operating the driving mechanism, when the second container descends, the upper-layer liquid of the centrifuged liquid sample in the first containing cavity can be squeezed into the drainage tube and flows into the second containing cavity through the drainage tube, so that the upper-layer liquid is separated from other liquid samples, the extraction is more convenient, impurities are not easy to mix, and the operation is easy to realize by one hand.)

1. A novel separation device is characterized in that:

comprises a first container, a second container, a sealing cover and a driving mechanism;

the first container is provided with a first cavity with an upward opening;

the second container is movably matched in the first cavity and is provided with a second cavity with an upward opening, the bottom surface of the second container is provided with a drainage tube, and the drainage tube enables the bottom surface of the second container to be communicated with the second cavity;

the sealing cover covers the opening of the first cavity;

the driving mechanism is arranged on the sealing cover, is in transmission connection with the second container and is used for driving the second container to perform lifting movement in the first container.

2. A novel separation device as claimed in claim 1, wherein:

the first container is made of a transparent, colorless material.

3. A novel separation device as claimed in claim 1, wherein:

the bottom surface of the second containing cavity is a drainage wall which is obliquely arranged, and the lowest part of the drainage wall is a collecting part.

4. A novel separation device as claimed in claim 3, wherein:

the top end of the drainage tube is provided with an inclined cut which is inclined in the same direction as the drainage wall.

5. A novel separation device as claimed in claim 1, wherein:

the lower extreme opening part of drainage tube sets up to the bellmouth that expands outward, the bore of bellmouth is the trend of crescent from top to bottom direction.

6. A novel separation device as claimed in claim 1, wherein:

the sealing cover is provided with a mounting hole for assembling the driving mechanism, and a sealing ring is arranged between the driving mechanism and the side wall of the mounting hole.

7. A novel separation device as claimed in claim 1, wherein:

the drainage tube also comprises a first needle arranged on the sealing cover, and the first needle penetrates through the sealing cover downwards and is inserted into the drainage tube.

8. A novel separation device as claimed in claim 1, wherein:

the needle assembly further comprises a second needle arranged on the sealing cover, and the second needle penetrates through the sealing cover downwards and is inserted into the second cavity.

9. A novel separation device as claimed in claim 1, wherein:

the outer side wall of the second container is in movable sealing fit with the inner side wall of the first container.

10. A novel separation device as claimed in claim 9, wherein:

and a sealing ring is arranged at the bottom end of the outer side wall of the second container, and the sealing ring is movably matched between the first container and the second container in a sealing manner.

11. A novel separation device as claimed in any one of claims 1 to 10, wherein:

the driving mechanism comprises a cover body which is in running fit with the upper end of the first container, and a linkage assembly which is arranged on the sealing cover and is in transmission connection with the second container, wherein the linkage assembly converts the rotary motion of the cover body into linear motion so as to drive the second container to perform lifting motion in the first container.

12. A novel separation device as claimed in claim 11, wherein:

the linkage assembly comprises a link rod, a gear and a linkage block;

the middle part of the link rod is rotationally matched on the sealing cover;

the gear is connected to the upper end of the link rod;

the inner side wall of the cover body is provided with an inner tooth surface for meshing the gear;

one end of the linkage block is in threaded connection with the lower end of the linkage rod, and the other end of the linkage block is connected to the drainage tube.

13. A novel separation device as claimed in claim 12, wherein:

the other end of the linkage block is sleeved on the drainage tube, a limiting groove is formed in the outer wall of the drainage tube, and the linkage block is embedded in the limiting groove.

14. A novel separation device as claimed in claim 12, wherein:

and the gear is connected with the upper end of the link rod through a key.

15. A novel separation device as claimed in claim 11, wherein:

the sealing cover is characterized in that an annular flange protruding along the radial direction of the sealing cover is arranged on the circumferential surface of the sealing cover, the cover body is provided with an annular groove matched with the annular flange, and the annular groove is sleeved on the annular flange.

16. A novel separation device as claimed in any one of claims 1 to 8, wherein:

the driving mechanism is an air conveying device arranged on the sealing cover and used for injecting air into the first container; the outer side wall of the second container is in movable sealing fit with the inner side wall of the first container.

17. A novel separation device as claimed in claim 16, wherein:

the gas transmission device is an injector.

18. A novel separation device as claimed in claim 16, wherein:

the sealing cover is provided with a mounting column for assembling the gas transmission device, and the gas outlet of the gas transmission device is in threaded connection with the mounting column.

19. A novel separation device as claimed in any one of claims 1 to 10, wherein:

the driving mechanism is a push-pull rod movably arranged on the sealing cover in a penetrating mode, and the lower end of the push-pull rod is connected with the drainage tube or the inner side wall of the second container.

Technical Field

The invention relates to the technical field of biological experiment equipment, in particular to a novel separation device.

Background

In the preparation of biological materials or biological experiments, blood/tissue samples are often crushed and then centrifuged to obtain layered samples, and then a needle is inserted into a centrifugal container by means of needle tube extraction to extract target substances. When the target substance is in the intermediate layer and the target substance layer is thin, the extraction operation is difficult, and other layered impurities may be extracted by manual shaking or shaking.

The existing centrifugal container adopts the necking down design in the middle of the container, the bottom of the container is sealed by a rubber plug, and a target substance layer is pushed upwards to the necking down position by pushing the rubber plug upwards during use. However, the centrifugal container adopts a design similar to an injector, and the push rod pushes the rubber plug, so that the following disadvantages are present:

the height of the container and the length of the exposed part of the push rod are equal to the total height of the centrifugal container, the height value of the centrifugal container is larger, and the push rod is positioned at the bottom of the container, so that the integral structure is not easy to be matched with a centrifugal machine; under the condition of not using external equipment, the operation of pushing the rubber plug upwards can be carried out only by using the other hand to assist in fixing the container, and due to the pressure in the container, the position of the rubber plug can be kept unchanged (namely the position of a target substance layer is kept unchanged) only by continuously applying force, namely, an operator needs to push the push rod and the fixed container respectively by two hands, so that the centrifugal container cannot be extracted any more, and the operation of the centrifugal container is difficult for a single person to use.

Disclosure of Invention

The invention aims to provide a novel separation device, which is designed to shorten the height of the whole structure and is more labor-saving and convenient to operate by one person.

In order to achieve the above purpose, the solution of the invention is:

a novel separation device comprises a first container, a second container, a sealing cover and a driving mechanism; the first container is provided with a first cavity with an upward opening; the second container is movably matched in the first cavity and is provided with a second cavity with an upward opening, the bottom surface of the second container is provided with a drainage tube, and the drainage tube enables the bottom surface of the second container to be communicated with the second cavity; the sealing cover covers the opening of the first cavity; the driving mechanism is arranged on the sealing cover, is in transmission connection with the second container and is used for driving the second container to perform lifting movement in the first container.

The first container is made of a transparent, colorless material.

The bottom surface of the second containing cavity is a drainage wall which is obliquely arranged, and the lowest part of the drainage wall is a collecting part.

The top end of the drainage tube is provided with an inclined cut which is inclined in the same direction as the drainage wall.

The lower extreme opening part of drainage tube sets up to the bellmouth that expands outward, the bore of bellmouth is the trend of crescent from top to bottom direction.

The sealing cover is provided with a mounting hole for assembling the driving mechanism, and a sealing ring is arranged between the driving mechanism and the side wall of the mounting hole.

The novel separation device further comprises a first needle arranged on the sealing cover, and the first needle penetrates through the sealing cover downwards and is inserted into the drainage tube.

The novel separation device further comprises a second needle arranged on the sealing cover, and the second needle penetrates through the sealing cover downwards and is inserted into the second cavity.

The outer side wall of the second container is in movable sealing fit with the inner side wall of the first container.

And a sealing ring is arranged at the bottom end of the outer side wall of the second container, and the sealing ring is movably matched between the first container and the second container in a sealing manner.

One embodiment of the drive mechanism is:

the driving mechanism comprises a cover body which is in running fit with the upper end of the first container, and a linkage assembly which is arranged on the sealing cover and is in transmission connection with the second container, wherein the linkage assembly converts the rotary motion of the cover body into linear motion so as to drive the second container to perform lifting motion in the first container.

The linkage assembly comprises a link rod, a gear and a linkage block; the middle part of the link rod is rotationally matched on the sealing cover; the gear is connected to the upper end of the link rod; the inner side wall of the cover body is provided with an inner tooth surface for meshing the gear; one end of the linkage block is in threaded connection with the lower end of the linkage rod, and the other end of the linkage block is connected to the drainage tube.

The other end of the linkage block is sleeved on the drainage tube, a limiting groove is formed in the outer wall of the drainage tube, and the linkage block is embedded in the limiting groove.

And the gear is connected with the upper end of the link rod through a key.

The sealing cover is characterized in that an annular flange protruding along the radial direction of the sealing cover is arranged on the circumferential surface of the sealing cover, the cover body is provided with an annular groove matched with the annular flange, and the annular groove is sleeved on the annular flange.

The second embodiment of the driving mechanism is:

the driving mechanism is an air conveying device arranged on the sealing cover and used for injecting air into the first container; the outer side wall of the second container is in movable sealing fit with the inner side wall of the first container.

The gas transmission device is an injector.

The sealing cover is provided with a mounting column for assembling the gas transmission device, and the gas outlet of the gas transmission device is in threaded connection with the mounting column.

The third embodiment of the driving mechanism is as follows:

the driving mechanism is a push-pull rod movably arranged on the sealing cover in a penetrating mode, and the lower end of the push-pull rod is connected with the drainage tube or the inner side wall of the second container.

After the technical scheme is adopted, the second container can be lifted in the first container by operating the driving mechanism, when the second container descends, the upper-layer liquid of the centrifuged liquid sample contained in the first containing cavity can be squeezed into the drainage tube and flows into the second containing cavity through the drainage tube, so that the separation of the upper-layer liquid and other liquid samples is realized, the extraction is more convenient, and impurities are not easy to mix; the second container is lifted in the first container all the time, the height of the whole structure is smaller, and the driving mechanism is positioned at the top of the first container, so that the final product is easier to assemble with the centrifuge; the driving mechanism is mainly used for driving the second container downwards, the force in the downward direction can enable the first container to be tightly attached to the workbench/plane, at the moment, the other hand can perform extraction action, and the operation is easier for a single person.

Drawings

FIG. 1 is a perspective view of a first embodiment of the present invention;

FIG. 2 is an exploded view of the first embodiment of the present invention;

FIG. 3 is a cross-sectional view of a first embodiment of the present invention;

FIG. 4 is a schematic diagram illustrating the operation of the first embodiment of the present invention;

FIG. 5 is a perspective view of a second embodiment of the present invention;

FIG. 6 is a cross-sectional view of a second embodiment of the present invention;

FIG. 7 is a perspective view of a third embodiment of the present invention;

FIG. 8 is a cross-sectional view of a third embodiment of the present invention;

the reference numbers illustrate:

1-a first container; 11-a first cavity; 2- -a second container;

21- - -a second cavity; 211-a drainage wall; 212- -drainage;

22- -a drainage tube; 221- -oblique cut; 222- -a limiting groove;

23- -a bell mouth; 3-a sealing cover; 31-a mounting hole;

32- -an annular flange; 33-mounting a post; 4-a sealing ring;

5- -a sealing ring; 6- -a first needle; 7- -a sealing cap;

8- -a second needle; 9- -a cover; 91-an annular groove;

92- -inner tooth surface; 10- -a link; 20- -a gear;

30-a linkage block; 40- -gas transmission equipment; 401- -air outlet;

50- -a push-pull rod; 60- -non-slip cap.

Detailed Description

In order to further explain the technical solution of the present invention, the present invention is explained in detail by the following specific examples.

The invention relates to a novel separation device, which comprises a first container 1, a second container 2, a sealing cover 3 and a driving mechanism, wherein the first container is arranged on the first container;

the first container 1 is provided with a first cavity 11 with an upward opening;

the second container 2 is movably matched in the first containing cavity 11 and is provided with a second containing cavity 21 with an upward opening, a drainage tube 22 is arranged in the middle of the bottom surface of the second container 2, and the drainage tube 22 enables the bottom surface of the second container 2 to be communicated with the second containing cavity 21;

the sealing cover 3 covers the opening of the first cavity 11;

the driving mechanism is arranged on the sealing cover 3 and is in transmission connection with the second container 2, and is used for driving the second container 2 to perform lifting movement in the first container 1.

Through the technical scheme, the second container 2 can be lifted in the first container 1 by operating the driving mechanism, when the second container 2 descends, the upper-layer liquid of the centrifuged liquid sample in the first containing cavity 11 can be squeezed into the drainage tube 22 and flows into the second containing cavity 21 through the drainage tube 22, so that the upper-layer liquid is separated from other liquid samples, the extraction is more convenient, and impurities are not easy to mix; the second container 2 is lifted in the first container 1 all the time, the height of the whole structure is smaller, and the driving mechanism is positioned at the top of the first container 1, so that the final product is easier to assemble with the centrifuge; the driving mechanism is mainly used for driving the second container 2 downwards, the force of the downward direction of the driving mechanism can enable the first container 1 to be tightly attached to a workbench/plane, at the moment, the other hand can perform extraction action, and the operation is easier for a single person.

The first container 1 is made of a transparent and colorless material, and the internal condition of the first container 1 can be observed when the container is used conveniently.

In order to improve the collecting effect of the second container 2, the bottom surface of the second cavity 21 is a drainage wall 211 which is obliquely arranged, and the lowest part of the drainage wall 211 is a collecting part 212. Specifically, drainage wall 211 can be the special-shaped similar arcwall face for the bottom of second appearance chamber 21 has a low-lying and takes as collection portion 212, when realizing that the liquid that drainage tube 22 upper end was flowed out falls to second appearance chamber 21 in, flows to the collection portion 212 of low department along drainage wall 211, because the cross-section of collection portion 212 further reduces for second appearance chamber 21, the liquid height increase of this position more conveniently extracts. Further, the top end of the draft tube 22 is provided with an inclined notch 221 inclined in the same direction as the draft wall 211, and when the liquid rises in the draft tube 22 to the inclined notch 221, it more easily flows to the collecting portion 212 of the second receiving chamber 21 due to the guiding action of the inclined notch 221.

The opening at the lower end of the drainage tube 22 is provided with an outward-expanding bell mouth 23, and the caliber of the bell mouth 23 gradually increases from the top to the bottom, so that the plane from the bell mouth 23 to the drainage tube 22 is in a smooth transition shape. The flare 23 can realize the function similar to that of the necking in the prior art, and especially in the separated sample, when the second container 2 descends, the upper layer liquid is generally guided out from the drainage tube 22 into the second containing cavity 21, and when the position of the middle layer liquid is located at the position of the flare 23, the thickness of the middle layer liquid is increased, so that the extraction is more convenient.

In order to prevent liquid from penetrating into the gap between the first container 1 and the second container 2, the outer side wall of the second container 2 is in movable sealing fit with the inner side wall of the first container 1. When the second container 2 moves downward, the liquid in the first chamber 11 does not leak from the gap between the first container 1 and the second container 2, but is pressed toward the draft tube 22 to flow into the second chamber 21. Further, the bottom end of the outer side wall of the second container 2 is provided with a sealing ring 4, and the sealing ring 4 is movably and hermetically matched between the first container 1 and the second container 2.

The sealing cover 3 is provided with a mounting hole 31 for assembling the driving mechanism, and a sealing ring 5 is arranged between the driving mechanism and the side wall of the mounting hole 31 so as to ensure the sealing effect of the assembly of the sealing cover 3 and the driving mechanism.

The present invention may further include a first needle 6 provided on the sealing cap 3, the first needle 6 penetrating downward through the sealing cap 3 and being inserted into the drainage tube 22. According to the actual use requirement, the first needle 6 can be used for injecting the sample to be centrifuged into the first cavity 11 before centrifugation, and can also be used for extracting the middle liquid in the drainage tube 22 (bell mouth 23) after centrifugation. Further, the first needle 6 is terminated with a standard luer fitting and fitted with a sealing cap 7.

The present invention may further comprise a second needle 8 provided on the sealing cap 3, the second needle 8 penetrating downward the sealing cap 3 and being inserted into the second receptacle 21. Further, the second needle 8 is directed to the collecting portion 212 of the second cavity 21 for extracting the liquid in the second cavity 21 after centrifugation; the second needle 8 terminates in a standard luer fitting and is fitted with a sealing cap 7'.

The drive mechanism may be implemented in a variety of ways depending on the mode of operation, and will be described below in connection with a number of specific embodiments of the present invention.

Referring to fig. 1 to 4, a first embodiment of the present invention is shown.

The driving mechanism comprises a cover body 9 which is in running fit with the upper end of the first container 1, and a linkage assembly which is arranged on the sealing cover 3 and is in transmission connection with the second container 2, wherein the linkage assembly converts the rotary motion of the cover body 9 into linear motion so as to drive the second container 2 to perform lifting motion in the first container 1. Can also cover sealed lid 3 after setting up lid 9, realize preventing dirty, effect such as dustproof.

The linkage assembly comprises a link rod 10, a gear 20 and a linkage block 30; the middle part of the connecting rod 10 is rotationally matched on the sealing cover 3; the gear 20 is connected to the upper end of the link rod 10, and the inner side wall of the cover body 9 is provided with an inner tooth surface 92 for meshing of the gear 20; one end of the linkage block 30 is connected with the lower end of the linkage rod 10 by screw threads, and the other end thereof is connected to the drainage tube 22. When the gear 20 is driven by the cover 9 to rotate, the gear 20 drives the link rod 10 to rotate, and due to the threaded connection between the link rod 10 and the linkage block 30, the link rod 10 can drive the linkage block 30 to go up and down, thereby driving the second container 2 to go up and down through the drainage tube 22. Through the transmission mode that the cover body 9 is meshed with the gear 20, the gear 20 is coaxially connected with the link rod 10, and the link rod 10 is in threaded connection with the link block 30, the link block 30 can be driven to lift by rotating the cover body 9, the diameter of the cover body 9 is larger, the diameter of the link rod 10 is smaller, the gear 20 is used for realizing speed reduction transmission, the purpose of accurately controlling the lifting height of the second container 2 can be achieved, and the operation is more labor-saving and simple.

Further, the other end of the linkage block 30 is sleeved on the drainage tube 22, the outer wall of the drainage tube 22 is provided with a limit groove 222 for the linkage block 30 to be embedded, the linkage block 30 is clamped in the limit groove 222, so that the linkage block 30 and the second container 2 are relatively fixed, and the linkage block 30 and the drainage tube 22 are separated and can be assembled after being produced by different materials and different molds; the gear 20 is in key connection with the upper end of the link rod 10, so that the detachable installation is realized.

Furthermore, an annular flange 32 protruding in the radial direction of the sealing cover 3 is disposed on the circumferential surface of the sealing cover 3, an annular groove 91 matching with the annular flange 32 is disposed on the cover body 9, the annular groove 91 is sleeved on the annular flange 32, so that the cover body 9 can be rotatably mounted on the sealing cover 3, and when the cover body 9 is rotated, the cover body 9 rotates with the annular flange 32 as a track, so as to change the relative angle with the first container 1, and realize the rotation motion of the cover body 9.

Referring to fig. 4, the working principle of the first embodiment is (the layered liquid is represented by different filling patterns in the figure, which is only an example, and not necessarily three layers):

when a centrifuged liquid sample needs to be extracted, the cover body 9 is screwed, the cover body 9 drives the gear 20 and the link rod 10 to synchronously rotate, the link rod 10 drives the link block 30, the drainage tube 22 and the second container 2 to synchronously descend, and due to the extrusion of the bottom surface of the second container 2 on the liquid sample, the liquid on the uppermost layer is extruded into the drainage tube 22, rises to the top end of the drainage tube 22, flows into the second containing cavity 21, and flows to the collecting part 212 at the lower part of the second containing cavity 21 along the drainage wall 211, so that the second needle 8 is convenient to extract. In addition, centrifugation may be performed again before the extraction of the upper liquid in the second chamber 21.

Referring to fig. 5 and 6, a second embodiment of the present invention is shown.

The driving mechanism is a gas transmission device 40 arranged on the sealing cover 3 and used for injecting air into the first container 1; the outer side wall of the second container 2 is in movable sealing fit with the inner side wall of the first container 1. When the air is injected into the first container 1, the air transmission device 40 fills the air into the second container 2 first because the space between the first container 1 and the second container 2 is sealed and the aperture of the drainage tube 22 is small, so that the air pressure above the second container 2 is greater than the air pressure below the second container 2, and the second container 2 is pushed to descend, thereby completing the liquid separation.

Further, the gas transmission device 40 is an injector, and has a simple structure and is easy to operate.

Further, the sealing cover 3 is provided with a mounting column 33 for assembling the gas transmission device 40, and the gas outlet 401 of the gas transmission device 40 is connected with the mounting column 33 by threads, so that the detachable installation is realized, and the structure is stable.

The working principle of the second embodiment is similar to that of the first embodiment, and only the driving manner is different, which is not described herein.

Referring to fig. 7 and 8, a third embodiment of the present invention is shown.

The driving mechanism is a push-pull rod 50 movably arranged through the sealing cover 3, the lower end of the push-pull rod 50 is connected with the drainage tube 22 or the inner side wall of the second container 1, and the upper end of the push-pull rod penetrates through the sealing cover 3 for operation. The push-pull rod 50 is arranged to drive the second container 2, the structure is simplest, and the cost is low.

Further, the third embodiment further includes an anti-slip cap 60 fitted over the upper end of the push-pull rod 50, so that the push-pull rod 50 is easier to handle and does not slip by hand.

Similarly, the working principle of the third embodiment is similar to that of the first embodiment, and only the driving manner is different, which is not described herein again.

In addition, other embodiments of the driving mechanism may also adopt a motor and a corresponding mechanical structure for driving, so as to realize mechanized and automated control, and the second container 2 is driven to ascend and descend more quickly and with higher precision, but the cost is also increased correspondingly.

The above embodiments and drawings are not intended to limit the form and style of the present invention, and any suitable changes or modifications thereof by those skilled in the art should be considered as not departing from the scope of the present invention.